4huq - Revision history

OCA at 11:44, 1 March 2024

OCA — Fri, 01 Mar 2024 11:44:55 GMT

←Older revision		Revision as of 11:44, 1 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4huq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Levilactobacillus_brevis_ATCC_367 Levilactobacillus brevis ATCC 367]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HUQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[4huq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Levilactobacillus_brevis_ATCC_367 Levilactobacillus brevis ATCC 367]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HUQ FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4huq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4huq OCA], [https://pdbe.org/4huq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4huq RCSB], [https://www.ebi.ac.uk/pdbsum/4huq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4huq ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.998Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4huq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4huq OCA], [https://pdbe.org/4huq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4huq RCSB], [https://www.ebi.ac.uk/pdbsum/4huq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4huq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/ECFA2_LEVBA ECFA2_LEVBA] ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.[HAMAP-Rule:MF_01710]		[https://www.uniprot.org/uniprot/ECFA2_LEVBA ECFA2_LEVBA] ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.[HAMAP-Rule:MF_01710]
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	ATP-binding cassette (ABC) transporters, composed of importers and exporters, form one of the biggest protein superfamilies that transport a variety of substrates across the membrane, powered by ATP hydrolysis. Most ABC transporters are composed of two transmembrane domains and two cytoplasmic nucleotide-binding domains. Also, importers from prokaryotes usually have extra solute-binding proteins in the periplasm that are responsible for the binding of substrates. Structures of importers have been reported that suggested a two-state model for the transport mechanism. Energy-coupling factor (ECF) transporters belong to a new class of ATP-binding cassette importers. Each ECF transporter comprises an energy-coupling module consisting of a transmembrane T protein (EcfT), two nucleotide-binding proteins (EcfA and EcfA'), and another transmembrane substrate-specific binding S protein (EcfS). Despite the similarities with ABC transporters, ECF transporters have different organizational and functional properties. The lack of solute-binding proteins in ECF transporters differentiates them clearly from the canonical ABC importers. Previously reported structures of the EcfS proteins RibU and ThiT clearly demonstrated the binding site of substrate riboflavin and thiamine, respectively. However, the organization of the four different components and the transport mechanism of ECF transporters remain unknown. Here we present the structure of an intact folate ECF transporter from Lactobacillus brevis at a resolution of 3 A. This structure was captured in an inward-facing, nucleotide-free conformation with no bound substrate. The folate-binding protein FolT is nearly parallel to the membrane and is bound almost entirely by EcfT, which adopts an L shape and connects to EcfA and EcfA' through two coupling helices. Two conserved XRX motifs from the coupling helices of EcfT have a vital role in energy coupling by docking into EcfA-EcfA'. We propose a transport model that involves a substantial conformational change of FolT.
-
-	Crystal structure of a folate energy-coupling factor transporter from Lactobacillus brevis.,Xu K, Zhang M, Zhao Q, Yu F, Guo H, Wang C, He F, Ding J, Zhang P Nature. 2013 Apr 14. doi: 10.1038/nature12046. PMID:23584589<ref>PMID:23584589</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4huq" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 08:16, 9 November 2022

OCA — Wed, 09 Nov 2022 08:16:54 GMT

←Older revision		Revision as of 08:16, 9 November 2022
Line 1:		Line 1:

	==Crystal Structure of a transporter==		==Crystal Structure of a transporter==
-	<StructureSection load='4huq' size='340' side='right' caption='[[4huq]], [[Resolution\|resolution]] 3.00Å' scene=''>	+	<StructureSection load='4huq' size='340' side='right'caption='[[4huq]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4huq]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Lacba Lacba~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4HUQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4huq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Levilactobacillus_brevis_ATCC_367 Levilactobacillus brevis ATCC 367]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HUQ FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cbiO1, ecfA1, LVIS_1661, unknown transporter ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=387344 LACBA]), ecfA2, cbiO2, LVIS_1662 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=387344 LACBA]), LVIS_0823 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=387344 LACBA]), ecfT, LVIS_1660 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=387344 LACBA])</td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4huq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4huq OCA], [https://pdbe.org/4huq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4huq RCSB], [https://www.ebi.ac.uk/pdbsum/4huq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4huq ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4huq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4huq OCA], [~~http~~://pdbe.org/4huq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4huq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4huq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4huq ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~ECFT_LACBA ECFT_LACBA~~]~~] Transmembrane~~ (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity). [[http://www.uniprot.org/uniprot/ECFA1_LACBA ECFA1_LACBA]] Part of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ~~(By similarity)~~. [~~[http~~:~~//www.uniprot.org/uniprot/ECFA2_LACBA ECFA2_LACBA~~]] Part of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity).	+	[https://www.uniprot.org/uniprot/ECFA2_LEVBA ECFA2_LEVBA] ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.[HAMAP-Rule:MF_01710]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Lacba~~]]	+	[[Category: Large Structures]]
-	[[Category: Xu, K]]	+	[[Category: Levilactobacillus brevis ATCC 367]]
-	[[Category: Yu, F]]	+	[[Category: Xu K]]
-	[[Category: Zhang, M]]	+	[[Category: Yu F]]
-	[[Category: Zhang, P]]	+	[[Category: Zhang M]]
-	[[Category: Zhao, Q]]	+	[[Category: Zhang P]]
-	~~[[Category: Hydrolase]]~~	+	[[Category: Zhao Q]]
-	~~[[Category: Transporter~~]]	+

OCA at 07:50, 4 August 2016

OCA — Thu, 04 Aug 2016 07:50:35 GMT

←Older revision		Revision as of 07:50, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal Structure of a transporter==		==Crystal Structure of a transporter==
	<StructureSection load='4huq' size='340' side='right' caption='[[4huq]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='4huq' size='340' side='right' caption='[[4huq]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4huq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Lactobacillus_brevis_atcc_367 Lactobacillus brevis atcc 367~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HUQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4huq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lacba Lacba]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HUQ FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cbiO1, ecfA1, LVIS_1661, unknown transporter ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=387344 ~~Lactobacillus brevis ATCC 367~~]), ecfA2, cbiO2, LVIS_1662 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=387344 ~~Lactobacillus brevis ATCC 367~~]), LVIS_0823 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=387344 ~~Lactobacillus brevis ATCC 367~~]), ecfT, LVIS_1660 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=387344 ~~Lactobacillus brevis ATCC 367~~])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cbiO1, ecfA1, LVIS_1661, unknown transporter ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=387344 LACBA]), ecfA2, cbiO2, LVIS_1662 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=387344 LACBA]), LVIS_0823 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=387344 LACBA]), ecfT, LVIS_1660 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=387344 LACBA])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4huq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4huq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4huq RCSB], [http://www.ebi.ac.uk/pdbsum/4huq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4huq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4huq OCA], [http://pdbe.org/4huq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4huq RCSB], [http://www.ebi.ac.uk/pdbsum/4huq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4huq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4huq" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Lactobacillus brevis atcc 367~~]]	+	[[Category: Lacba]]
	[[Category: Xu, K]]		[[Category: Xu, K]]
	[[Category: Yu, F]]		[[Category: Yu, F]]

OCA at 07:04, 25 December 2014

OCA — Thu, 25 Dec 2014 07:04:26 GMT

←Older revision		Revision as of 07:04, 25 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4huq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4huq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4huq RCSB], [http://www.ebi.ac.uk/pdbsum/4huq PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4huq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4huq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4huq RCSB], [http://www.ebi.ac.uk/pdbsum/4huq PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ECFT_LACBA ECFT_LACBA]] Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity). [[http://www.uniprot.org/uniprot/ECFA1_LACBA ECFA1_LACBA]] Part of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity). [[http://www.uniprot.org/uniprot/ECFA2_LACBA ECFA2_LACBA]] Part of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 12:40, 21 December 2014

OCA — Sun, 21 Dec 2014 12:40:25 GMT

←Older revision		Revision as of 12:40, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4huq\| PDB~~=4huq \| ~~SCENE~~= }}	+	==Crystal Structure of a transporter==
-	===~~Crystal Structure of~~ a transporter===	+	<StructureSection load='4huq' size='340' side='right' caption='[[4huq]], [[Resolution\|resolution]] 3.00Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23584589}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4huq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_brevis_atcc_367 Lactobacillus brevis atcc 367]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HUQ FirstGlance]. <br>
		+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cbiO1, ecfA1, LVIS_1661, unknown transporter ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=387344 Lactobacillus brevis ATCC 367]), ecfA2, cbiO2, LVIS_1662 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=387344 Lactobacillus brevis ATCC 367]), LVIS_0823 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=387344 Lactobacillus brevis ATCC 367]), ecfT, LVIS_1660 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=387344 Lactobacillus brevis ATCC 367])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4huq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4huq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4huq RCSB], [http://www.ebi.ac.uk/pdbsum/4huq PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	ATP-binding cassette (ABC) transporters, composed of importers and exporters, form one of the biggest protein superfamilies that transport a variety of substrates across the membrane, powered by ATP hydrolysis. Most ABC transporters are composed of two transmembrane domains and two cytoplasmic nucleotide-binding domains. Also, importers from prokaryotes usually have extra solute-binding proteins in the periplasm that are responsible for the binding of substrates. Structures of importers have been reported that suggested a two-state model for the transport mechanism. Energy-coupling factor (ECF) transporters belong to a new class of ATP-binding cassette importers. Each ECF transporter comprises an energy-coupling module consisting of a transmembrane T protein (EcfT), two nucleotide-binding proteins (EcfA and EcfA'), and another transmembrane substrate-specific binding S protein (EcfS). Despite the similarities with ABC transporters, ECF transporters have different organizational and functional properties. The lack of solute-binding proteins in ECF transporters differentiates them clearly from the canonical ABC importers. Previously reported structures of the EcfS proteins RibU and ThiT clearly demonstrated the binding site of substrate riboflavin and thiamine, respectively. However, the organization of the four different components and the transport mechanism of ECF transporters remain unknown. Here we present the structure of an intact folate ECF transporter from Lactobacillus brevis at a resolution of 3 A. This structure was captured in an inward-facing, nucleotide-free conformation with no bound substrate. The folate-binding protein FolT is nearly parallel to the membrane and is bound almost entirely by EcfT, which adopts an L shape and connects to EcfA and EcfA' through two coupling helices. Two conserved XRX motifs from the coupling helices of EcfT have a vital role in energy coupling by docking into EcfA-EcfA'. We propose a transport model that involves a substantial conformational change of FolT.

-	~~==Function==~~	+	Crystal structure of a folate energy-coupling factor transporter from Lactobacillus brevis.,Xu K, Zhang M, Zhao Q, Yu F, Guo H, Wang C, He F, Ding J, Zhang P Nature. 2013 Apr 14. doi: 10.1038/nature12046. PMID:23584589<ref>PMID:23584589</ref>
-	~~[[http://www.uniprot.org/uniprot/ECFT_LACBA ECFT_LACBA]] Transmembrane (T) component~~ of an energy-coupling factor ~~(ECF) ABC-~~transporter ~~complex~~. ~~Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)~~. ~~[[http~~:~~//www.uniprot~~.~~org~~/uniprot/ECFA1_LACBA ECFA1_LACBA]] Part of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity). ~~[[http~~://www.uniprot.org/uniprot/ECFA2_LACBA ECFA2_LACBA]] Part of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity).	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[4huq]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Lactobacillus_brevis_atcc_367 Lactobacillus brevis atcc 367]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4HUQ OCA].~~	+	</div>
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:023584589</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Lactobacillus brevis atcc 367]]		[[Category: Lactobacillus brevis atcc 367]]
-	[[Category: Xu, K.]]	+	[[Category: Xu, K]]
-	[[Category: Yu, F.]]	+	[[Category: Yu, F]]
-	[[Category: Zhang, M.]]	+	[[Category: Zhang, M]]
-	[[Category: Zhang, P.]]	+	[[Category: Zhang, P]]
-	[[Category: Zhao, Q.]]	+	[[Category: Zhao, Q]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Transporter]]		[[Category: Transporter]]

OCA at 06:37, 20 June 2013

OCA — Thu, 20 Jun 2013 06:37:04 GMT

←Older revision		Revision as of 06:37, 20 June 2013
Line 8:		Line 8:
	==About this Structure==		==About this Structure==
	[[4huq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_brevis_atcc_367 Lactobacillus brevis atcc 367]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUQ OCA].		[[4huq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_brevis_atcc_367 Lactobacillus brevis atcc 367]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUQ OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:023584589</ref><references group="xtra"/><references/>
	[[Category: Lactobacillus brevis atcc 367]]		[[Category: Lactobacillus brevis atcc 367]]
	[[Category: Xu, K.]]		[[Category: Xu, K.]]

OCA at 06:48, 2 May 2013

OCA — Thu, 02 May 2013 06:48:56 GMT

←Older revision		Revision as of 06:48, 2 May 2013
Line 1:		Line 1:
	{{STRUCTURE_4huq\| PDB=4huq \| SCENE= }}		{{STRUCTURE_4huq\| PDB=4huq \| SCENE= }}
	===Crystal Structure of a transporter===		===Crystal Structure of a transporter===
		+	{{ABSTRACT_PUBMED_23584589}}

	==Function==		==Function==

OCA at 20:34, 17 April 2013

OCA — Wed, 17 Apr 2013 20:34:11 GMT

←Older revision		Revision as of 20:34, 17 April 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4huq\| PDB=4huq \| SCENE= }}
		+	===Crystal Structure of a transporter===

-	~~The entry 4huq is ON HOLD until Paper Publication~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/ECFT_LACBA ECFT_LACBA]] Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity). [[http://www.uniprot.org/uniprot/ECFA1_LACBA ECFA1_LACBA]] Part of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity). [[http://www.uniprot.org/uniprot/ECFA2_LACBA ECFA2_LACBA]] Part of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity).

-	~~Authors~~: ~~Zhang, P~~., Xu, K., Zhang, M., Zhao, Q.~~, Yu, F.~~	+	==About this Structure==
-		+	[[4huq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_brevis_atcc_367 Lactobacillus brevis atcc 367]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUQ OCA].
-	~~Description~~: ~~Crystal Structure of a transporter~~	+	[[Category: Lactobacillus brevis atcc 367]]
		+	[[Category: Xu, K.]]
		+	[[Category: Yu, F.]]
		+	[[Category: Zhang, M.]]
		+	[[Category: Zhang, P.]]
		+	[[Category: Zhao, Q.]]
		+	[[Category: Hydrolase]]
		+	[[Category: Transporter]]

OCA at 20:45, 12 December 2012

OCA — Wed, 12 Dec 2012 20:45:10 GMT

←Older revision		Revision as of 20:45, 12 December 2012
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4huq is ON HOLD	+	The entry 4huq is ON HOLD until Paper Publication

	Authors: Zhang, P., Xu, K., Zhang, M., Zhao, Q., Yu, F.		Authors: Zhang, P., Xu, K., Zhang, M., Zhao, Q., Yu, F.

	Description: Crystal Structure of a transporter		Description: Crystal Structure of a transporter

OCA at 09:07, 21 November 2012

OCA — Wed, 21 Nov 2012 09:07:23 GMT

←Older revision		Revision as of 09:07, 21 November 2012
Line 3:		Line 3:
	The entry 4huq is ON HOLD		The entry 4huq is ON HOLD

-	Authors: Zhang, ~~Peng~~, Xu, Ke, Zhang, ~~Minhua~~, Zhao, ~~Qin~~, Yu, ~~Fang~~	+	Authors: Zhang, P., Xu, K., Zhang, M., Zhao, Q., Yu, F.

	Description: Crystal Structure of a transporter		Description: Crystal Structure of a transporter