4hyy - Revision history

OCA at 15:12, 20 September 2023

OCA — Wed, 20 Sep 2023 15:12:49 GMT

←Older revision		Revision as of 15:12, 20 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4hyy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HYY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HYY FirstGlance]. <br>		<table><tr><td colspan='2'>[[4hyy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HYY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HYY FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hyy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hyy OCA], [https://pdbe.org/4hyy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hyy RCSB], [https://www.ebi.ac.uk/pdbsum/4hyy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hyy ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.603Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hyy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hyy OCA], [https://pdbe.org/4hyy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hyy RCSB], [https://www.ebi.ac.uk/pdbsum/4hyy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hyy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 08:27, 9 November 2022

OCA — Wed, 09 Nov 2022 08:27:57 GMT

←Older revision		Revision as of 08:27, 9 November 2022
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	==Filament of octameric rings of DMC1 recombinase from Homo sapiens==		==Filament of octameric rings of DMC1 recombinase from Homo sapiens==
-	<StructureSection load='4hyy' size='340' side='right' caption='[[4hyy]], [[Resolution\|resolution]] 2.60Å' scene=''>	+	<StructureSection load='4hyy' size='340' side='right'caption='[[4hyy]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4hyy]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HYY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4HYY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4hyy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HYY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HYY FirstGlance]. <br>
-	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v5w\|1v5w]]</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hyy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hyy OCA], [https://pdbe.org/4hyy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hyy RCSB], [https://www.ebi.ac.uk/pdbsum/4hyy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hyy ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DMC1, DMC1H, LIM15 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4hyy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hyy OCA], [~~http~~://pdbe.org/4hyy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4hyy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4hyy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4hyy ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/DMC1_HUMAN DMC1_HUMAN]] May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks (By similarity).	+	[https://www.uniprot.org/uniprot/DMC1_HUMAN DMC1_HUMAN] May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: ~~Du, L~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Luo, Y~~]]	+	[[Category: Du L]]
-	[[Category: ~~Dna]]~~	+	[[Category: Luo Y]]
-	~~[[Category: Dna strand exchange]]~~	+
-	~~[[Category: Nucleus]]~~	+
-	~~[[Category: Reca homolog]]~~	+
-	~~[[Category: Recombination~~]]	+

OCA at 10:56, 4 August 2016

OCA — Thu, 04 Aug 2016 10:56:37 GMT

←Older revision		Revision as of 10:56, 4 August 2016
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		+
	==Filament of octameric rings of DMC1 recombinase from Homo sapiens==		==Filament of octameric rings of DMC1 recombinase from Homo sapiens==
	<StructureSection load='4hyy' size='340' side='right' caption='[[4hyy]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='4hyy' size='340' side='right' caption='[[4hyy]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4hyy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HYY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HYY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4hyy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HYY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HYY FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v5w\|1v5w]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v5w\|1v5w]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DMC1, DMC1H, LIM15 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DMC1, DMC1H, LIM15 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hyy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hyy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hyy RCSB], [http://www.ebi.ac.uk/pdbsum/4hyy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hyy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hyy OCA], [http://pdbe.org/4hyy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hyy RCSB], [http://www.ebi.ac.uk/pdbsum/4hyy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hyy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4hyy" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Du, L]]		[[Category: Du, L]]
	[[Category: Luo, Y]]		[[Category: Luo, Y]]

OCA at 13:33, 24 December 2014

OCA — Wed, 24 Dec 2014 13:33:41 GMT

←Older revision		Revision as of 13:33, 24 December 2014
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hyy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hyy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hyy RCSB], [http://www.ebi.ac.uk/pdbsum/4hyy PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hyy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hyy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hyy RCSB], [http://www.ebi.ac.uk/pdbsum/4hyy PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/DMC1_HUMAN DMC1_HUMAN]] May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 12:01, 21 December 2014

OCA — Sun, 21 Dec 2014 12:01:58 GMT

←Older revision		Revision as of 12:01, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4hyy\| PDB=4hyy \| SCENE= }}~~	+	==Filament of octameric rings of DMC1 recombinase from Homo sapiens==
-	===Filament of octameric rings of DMC1 recombinase from Homo sapiens===	+	<StructureSection load='4hyy' size='340' side='right' caption='[[4hyy]], [[Resolution\|resolution]] 2.60Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23545642}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4hyy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HYY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HYY FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v5w\|1v5w]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DMC1, DMC1H, LIM15 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hyy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hyy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hyy RCSB], [http://www.ebi.ac.uk/pdbsum/4hyy PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Eukaryal DMC1 proteins play a central role in homologous recombination in meiosis by assembling at the sites of programmed DNA double-strand breaks and carrying out a search for allelic DNA sequences located on homologous chromatids. They are close homologs of eukaryal Rad51 and archaeal RadA proteins and are remote homologs of bacterial RecA proteins. These recombinases (also called DNA strand-exchange proteins) promote a pivotal strand-exchange reaction between homologous single-stranded and double-stranded DNA substrates. An octameric form of a truncated human DMC1 devoid of its small N-terminal domain (residues 1-83) has been crystallized. The structure of the truncated DMC1 octamer is similar to that of the previously reported full-length DMC1 octamer, which has disordered N-terminal domains. In each protomer, only the ATP cap regions (Asp317-Glu323) show a noticeable conformational difference. The truncated DMC1 octamers further stack with alternate polarity into a filament. Similar filamentous assemblies of DMC1 have been observed to form on DNA by electron microscopy.

-	~~==Function==~~	+	Structure of a filament of stacked octamers of human DMC1 recombinase.,Du L, Luo Y Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Apr 1;69(Pt 4):382-6. doi:, 10.1107/S1744309113005678. Epub 2013 Mar 28. PMID:23545642<ref>PMID:23545642</ref>
-	~~[[http://www~~.~~uniprot.org/uniprot/DMC1_HUMAN DMC1_HUMAN]] May participate in meiotic recombination~~, ~~specifically in homologous strand assimilation~~, ~~which is required for the resolution of meiotic double-strand breaks~~ (~~By similarity~~).	+

-	==~~About this Structure~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[4hyy]] is a 4 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HYY OCA].~~	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Du, L.]]	+	[[Category: Du, L]]
-	[[Category: Luo, Y.]]	+	[[Category: Luo, Y]]
	[[Category: Dna]]		[[Category: Dna]]
	[[Category: Dna strand exchange]]		[[Category: Dna strand exchange]]

OCA at 22:45, 10 April 2013

OCA — Wed, 10 Apr 2013 22:45:33 GMT

←Older revision		Revision as of 22:45, 10 April 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4hyy\| PDB=4hyy \| SCENE= }}
		+	===Filament of octameric rings of DMC1 recombinase from Homo sapiens===
		+	{{ABSTRACT_PUBMED_23545642}}

-	~~The entry 4hyy~~ is ~~ON HOLD until Paper Publication~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/DMC1_HUMAN DMC1_HUMAN]] May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks (By similarity).

-	~~Authors~~: Du, L., Luo, Y.	+	==About this Structure==
-		+	[[4hyy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HYY OCA].
-	~~Description~~: ~~Filament of octameric rings of DMC1 recombinase from Homo sapiens~~	+	[[Category: Homo sapiens]]
		+	[[Category: Du, L.]]
		+	[[Category: Luo, Y.]]
		+	[[Category: Dna]]
		+	[[Category: Dna strand exchange]]
		+	[[Category: Nucleus]]
		+	[[Category: Reca homolog]]
		+	[[Category: Recombination]]

OCA at 14:05, 28 November 2012

OCA — Wed, 28 Nov 2012 14:05:12 GMT

←Older revision		Revision as of 14:05, 28 November 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4hyy is ON HOLD	+	The entry 4hyy is ON HOLD until Paper Publication

	Authors: Du, L., Luo, Y.		Authors: Du, L., Luo, Y.

	Description: Filament of octameric rings of DMC1 recombinase from Homo sapiens		Description: Filament of octameric rings of DMC1 recombinase from Homo sapiens

OCA: Protected "4hyy" [edit=sysop:move=sysop]

OCA — Wed, 21 Nov 2012 09:10:33 GMT

Protected "4hyy" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:10, 21 November 2012

OCA: New page: '''Unreleased structure''' The entry 4hyy is ON HOLD Authors: Du, L., Luo, Y. Description: Filament of octameric rings of DMC1 recombinase from Homo sapiens

OCA — Wed, 21 Nov 2012 09:10:32 GMT

New page: '''Unreleased structure''' The entry 4hyy is ON HOLD Authors: Du, L., Luo, Y. Description: Filament of octameric rings of DMC1 recombinase from Homo sapiens

New page

'''Unreleased structure'''

The entry 4hyy is ON HOLD

Authors: Du, L., Luo, Y.

Description: Filament of octameric rings of DMC1 recombinase from Homo sapiens