4i0n - Revision history

OCA at 08:52, 20 March 2024

OCA — Wed, 20 Mar 2024 08:52:27 GMT

←Older revision		Revision as of 08:52, 20 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4i0n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I0N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I0N FirstGlance]. <br>		<table><tr><td colspan='2'>[[4i0n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I0N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I0N FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i0n OCA], [https://pdbe.org/4i0n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i0n RCSB], [https://www.ebi.ac.uk/pdbsum/4i0n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i0n ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i0n OCA], [https://pdbe.org/4i0n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i0n RCSB], [https://www.ebi.ac.uk/pdbsum/4i0n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i0n ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/A8ULG6_CLOPF A8ULG6_CLOPF]		[https://www.uniprot.org/uniprot/A8ULG6_CLOPF A8ULG6_CLOPF]
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Clostridium perfringens is an anaerobic bacterium that causes numerous important human and animal diseases, primarily as a result of its ability to produce many different protein toxins. In chickens, C. perfringens causes necrotic enteritis, a disease of economic importance to the worldwide poultry industry. The secreted pore-forming toxin NetB is a key virulence factor in the pathogenesis of avian necrotic enteritis and is similar to alpha-hemolysin, a beta-barrel pore-forming toxin from Staphylococcus aureus. To address the molecular mechanisms underlying NetB-mediated tissue damage, we determined the crystal structure of the monomeric form of NetB to 1.8 A. Structural comparisons with other members of the alpha-hemolysin family revealed significant differences in the conformation of the membrane binding domain. These data suggested that NetB may recognize different membrane receptors or use a different mechanism for membrane-protein interactions. Consistent with this idea, electrophysiological experiments with planar lipid bilayers revealed that NetB formed pores with much larger single-channel conductance than alpha-hemolysin. Channel conductance varied with phospholipid net charge. Furthermore, NetB differed in its ion selectivity, preferring cations over anions. Using hemolysis as a screen, we carried out a random-mutagenesis study that identified several residues that are critical for NetB-induced cell lysis. Mapping of these residues onto the crystal structure revealed that they were clustered in regions predicted to be required for oligomerization or membrane binding. Together these data provide an insight into the mechanism of NetB-mediated pore formation and will contribute to our understanding of the mode of action of this important toxin. IMPORTANCE Necrotic enteritis is an economically important disease of the worldwide poultry industry and is mediated by Clostridium perfringens strains that produce NetB, a beta-pore-forming toxin. We carried out structural and functional studies of NetB to provide a mechanistic insight into its mode of action and to assist in the development of a necrotic enteritis vaccine. We determined the structure of the monomeric form of NetB to 1.8 A, used both site-directed and random mutagenesis to identify key residues that are required for its biological activity, and analyzed pore formation by NetB and its substitution-containing derivatives in planar lipid bilayers.
-
-	Structural and functional analysis of the pore-forming toxin NetB from Clostridium perfringens.,Yan XX, Porter CJ, Hardy SP, Steer D, Smith AI, Quinsey NS, Hughes V, Cheung JK, Keyburn AL, Kaldhusdal M, Moore RJ, Bannam TL, Whisstock JC, Rood JI MBio. 2013 Feb 5;4(1):e00019-13. doi: 10.1128/mBio.00019-13. PMID:23386432<ref>PMID:23386432</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4i0n" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 08:31, 9 November 2022

OCA — Wed, 09 Nov 2022 08:31:25 GMT

←Older revision		Revision as of 08:31, 9 November 2022
Line 1:		Line 1:

	==Pore forming protein==		==Pore forming protein==
-	<StructureSection load='4i0n' size='340' side='right' caption='[[4i0n]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='4i0n' size='340' side='right'caption='[[4i0n]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4i0n]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_perfringens"_veillon_and_zuber_1898 "bacillus~~ perfringens~~" veillon and zuber 1898~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I0N OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4I0N FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4i0n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I0N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I0N FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">netB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1502 "Bacillus perfringens" Veillon and Zuber 1898])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i0n OCA], [https://pdbe.org/4i0n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i0n RCSB], [https://www.ebi.ac.uk/pdbsum/4i0n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i0n ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4i0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i0n OCA], [~~http~~://pdbe.org/4i0n PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4i0n RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4i0n PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4i0n ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A8ULG6_CLOPF A8ULG6_CLOPF]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ perfringens ~~veillon and zuber 1898~~]]	+	[[Category: Clostridium perfringens]]
-	[[Category: Bannam~~, T L~~]]	+	[[Category: Large Structures]]
-	[[Category: Cheung~~, J K~~]]	+	[[Category: Bannam TL]]
-	[[Category: Hardy~~, S P~~]]	+	[[Category: Cheung JK]]
-	[[Category: Hughes, V]]	+	[[Category: Hardy SP]]
-	[[Category: Kaldhusdal, M]]	+	[[Category: Hughes V]]
-	[[Category: Keyburn~~, A L~~]]	+	[[Category: Kaldhusdal M]]
-	[[Category: Moore~~, R J~~]]	+	[[Category: Keyburn AL]]
-	[[Category: Porter~~, C J~~]]	+	[[Category: Moore RJ]]
-	[[Category: Quinset, N]]	+	[[Category: Porter CJ]]
-	[[Category: Rood~~, J I~~]]	+	[[Category: Quinset N]]
-	[[Category: Smith~~, A I~~]]	+	[[Category: Rood JI]]
-	[[Category: Steer, D]]	+	[[Category: Smith AI]]
-	[[Category: Whisstock~~, J C~~]]	+	[[Category: Steer D]]
-	[[Category: Yan, X]]	+	[[Category: Whisstock JC]]
-	~~[[Category: Alpha-hemolysin fold]]~~	+	[[Category: Yan X]]
-	~~[[Category: Pore forming protein]]~~	+
-	~~[[Category: Toxin~~]]	+

OCA at 07:21, 23 December 2016

OCA — Fri, 23 Dec 2016 07:21:17 GMT

←Older revision		Revision as of 07:21, 23 December 2016
Line 1:		Line 1:
		+
	==Pore forming protein==		==Pore forming protein==
	<StructureSection load='4i0n' size='340' side='right' caption='[[4i0n]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='4i0n' size='340' side='right' caption='[[4i0n]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4i0n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptomyces_aureorectus Streptomyces aureorectus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I0N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I0N FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4i0n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_perfringens"_veillon_and_zuber_1898 "bacillus perfringens" veillon and zuber 1898]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I0N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I0N FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">netB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~285571 Streptomyces aureorectus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">netB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1502 "Bacillus perfringens" Veillon and Zuber 1898])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i0n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4i0n RCSB], [http://www.ebi.ac.uk/pdbsum/4i0n PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i0n OCA], [http://pdbe.org/4i0n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4i0n RCSB], [http://www.ebi.ac.uk/pdbsum/4i0n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4i0n ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4i0n" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Streptomyces aureorectus~~]]	+	[[Category: Bacillus perfringens veillon and zuber 1898]]
	[[Category: Bannam, T L]]		[[Category: Bannam, T L]]
	[[Category: Cheung, J K]]		[[Category: Cheung, J K]]

OCA at 07:18, 15 February 2015

OCA — Sun, 15 Feb 2015 07:18:52 GMT

←Older revision		Revision as of 07:18, 15 February 2015
Line 1:		Line 1:
-	~~{{STRUCTURE_4i0n~~\| ~~PDB~~=4i0n \| ~~SCENE~~= }}	+	==Pore forming protein==
-	===~~Pore forming protein~~===	+	<StructureSection load='4i0n' size='340' side='right' caption='[[4i0n]], [[Resolution\|resolution]] 1.80Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23386432}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4i0n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_aureorectus Streptomyces aureorectus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I0N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I0N FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">netB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=285571 Streptomyces aureorectus])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i0n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4i0n RCSB], [http://www.ebi.ac.uk/pdbsum/4i0n PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Clostridium perfringens is an anaerobic bacterium that causes numerous important human and animal diseases, primarily as a result of its ability to produce many different protein toxins. In chickens, C. perfringens causes necrotic enteritis, a disease of economic importance to the worldwide poultry industry. The secreted pore-forming toxin NetB is a key virulence factor in the pathogenesis of avian necrotic enteritis and is similar to alpha-hemolysin, a beta-barrel pore-forming toxin from Staphylococcus aureus. To address the molecular mechanisms underlying NetB-mediated tissue damage, we determined the crystal structure of the monomeric form of NetB to 1.8 A. Structural comparisons with other members of the alpha-hemolysin family revealed significant differences in the conformation of the membrane binding domain. These data suggested that NetB may recognize different membrane receptors or use a different mechanism for membrane-protein interactions. Consistent with this idea, electrophysiological experiments with planar lipid bilayers revealed that NetB formed pores with much larger single-channel conductance than alpha-hemolysin. Channel conductance varied with phospholipid net charge. Furthermore, NetB differed in its ion selectivity, preferring cations over anions. Using hemolysis as a screen, we carried out a random-mutagenesis study that identified several residues that are critical for NetB-induced cell lysis. Mapping of these residues onto the crystal structure revealed that they were clustered in regions predicted to be required for oligomerization or membrane binding. Together these data provide an insight into the mechanism of NetB-mediated pore formation and will contribute to our understanding of the mode of action of this important toxin. IMPORTANCE Necrotic enteritis is an economically important disease of the worldwide poultry industry and is mediated by Clostridium perfringens strains that produce NetB, a beta-pore-forming toxin. We carried out structural and functional studies of NetB to provide a mechanistic insight into its mode of action and to assist in the development of a necrotic enteritis vaccine. We determined the structure of the monomeric form of NetB to 1.8 A, used both site-directed and random mutagenesis to identify key residues that are required for its biological activity, and analyzed pore formation by NetB and its substitution-containing derivatives in planar lipid bilayers.

-	~~==About this Structure==~~	+	Structural and functional analysis of the pore-forming toxin NetB from Clostridium perfringens.,Yan XX, Porter CJ, Hardy SP, Steer D, Smith AI, Quinsey NS, Hughes V, Cheung JK, Keyburn AL, Kaldhusdal M, Moore RJ, Bannam TL, Whisstock JC, Rood JI MBio. 2013 Feb 5;4(1):e00019-13. doi: 10.1128/mBio.00019-13. PMID:23386432<ref>PMID:23386432</ref>
-	~~[[4i0n]] is a 1 chain structure with sequence~~ from ~~[http~~:~~//en~~.~~wikipedia~~.~~org~~/~~wiki/Streptomyces_aureorectus Streptomyces aureorectus]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id~~=~~4I0N OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Streptomyces aureorectus]]		[[Category: Streptomyces aureorectus]]
-	[[Category: Bannam, T L.]]	+	[[Category: Bannam, T L]]
-	[[Category: Cheung, J K.]]	+	[[Category: Cheung, J K]]
-	[[Category: Hardy, S P.]]	+	[[Category: Hardy, S P]]
-	[[Category: Hughes, V.]]	+	[[Category: Hughes, V]]
-	[[Category: Kaldhusdal, M.]]	+	[[Category: Kaldhusdal, M]]
-	[[Category: Keyburn, A L.]]	+	[[Category: Keyburn, A L]]
-	[[Category: Moore, R J.]]	+	[[Category: Moore, R J]]
-	[[Category: Porter, C J.]]	+	[[Category: Porter, C J]]
-	[[Category: Quinset, N.]]	+	[[Category: Quinset, N]]
-	[[Category: Rood, J I.]]	+	[[Category: Rood, J I]]
-	[[Category: Smith, A I.]]	+	[[Category: Smith, A I]]
-	[[Category: Steer, D.]]	+	[[Category: Steer, D]]
-	[[Category: Whisstock, J C.]]	+	[[Category: Whisstock, J C]]
-	[[Category: Yan, X.]]	+	[[Category: Yan, X]]
	[[Category: Alpha-hemolysin fold]]		[[Category: Alpha-hemolysin fold]]
	[[Category: Pore forming protein]]		[[Category: Pore forming protein]]
	[[Category: Toxin]]		[[Category: Toxin]]

OCA at 22:00, 10 April 2013

OCA — Wed, 10 Apr 2013 22:00:36 GMT

←Older revision		Revision as of 22:00, 10 April 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4i0n\| PDB=4i0n \| SCENE= }}
		+	===Pore forming protein===
		+	{{ABSTRACT_PUBMED_23386432}}

-	~~The entry~~ 4i0n is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
-		+	[[4i0n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_aureorectus Streptomyces aureorectus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I0N OCA].
-	~~Authors~~: ~~Yan~~, X., ~~Porter, C.~~J., Hardy, S.P.~~, Steer, D., Smith, A.I., Quinset, N.,~~ Hughes, V., ~~Cheung, J~~.~~K.,~~ Keyburn, A.L.~~, Kaldhusdal, M.,~~ Moore, R.J., ~~Bannam~~, T.L., Whisstock, J.C., ~~Rood, J.I~~.	+	[[Category: Streptomyces aureorectus]]
-		+	[[Category: Bannam, T L.]]
-	~~Description~~: Pore forming protein	+	[[Category: Cheung, J K.]]
		+	[[Category: Hardy, S P.]]
		+	[[Category: Hughes, V.]]
		+	[[Category: Kaldhusdal, M.]]
		+	[[Category: Keyburn, A L.]]
		+	[[Category: Moore, R J.]]
		+	[[Category: Porter, C J.]]
		+	[[Category: Quinset, N.]]
		+	[[Category: Rood, J I.]]
		+	[[Category: Smith, A I.]]
		+	[[Category: Steer, D.]]
		+	[[Category: Whisstock, J C.]]
		+	[[Category: Yan, X.]]
		+	[[Category: Alpha-hemolysin fold]]
		+	[[Category: Pore forming protein]]
		+	[[Category: Toxin]]

OCA at 10:31, 5 December 2012

OCA — Wed, 05 Dec 2012 10:31:14 GMT

←Older revision		Revision as of 10:31, 5 December 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4i0n is ON HOLD	+	The entry 4i0n is ON HOLD until Paper Publication

	Authors: Yan, X., Porter, C.J., Hardy, S.P., Steer, D., Smith, A.I., Quinset, N., Hughes, V., Cheung, J.K., Keyburn, A.L., Kaldhusdal, M., Moore, R.J., Bannam, T.L., Whisstock, J.C., Rood, J.I.		Authors: Yan, X., Porter, C.J., Hardy, S.P., Steer, D., Smith, A.I., Quinset, N., Hughes, V., Cheung, J.K., Keyburn, A.L., Kaldhusdal, M., Moore, R.J., Bannam, T.L., Whisstock, J.C., Rood, J.I.

	Description: Pore forming protein		Description: Pore forming protein

OCA: Protected "4i0n" [edit=sysop:move=sysop]

OCA — Wed, 28 Nov 2012 14:06:27 GMT

Protected "4i0n" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:06, 28 November 2012

OCA: New page: '''Unreleased structure''' The entry 4i0n is ON HOLD Authors: Yan, X., Porter, C.J., Hardy, S.P., Steer, D., Smith, A.I., Quinset, N., Hughes, V., Cheung, J.K., Keyburn, A.L., Kaldhusda...

OCA — Wed, 28 Nov 2012 14:06:26 GMT

New page: '''Unreleased structure''' The entry 4i0n is ON HOLD Authors: Yan, X., Porter, C.J., Hardy, S.P., Steer, D., Smith, A.I., Quinset, N., Hughes, V., Cheung, J.K., Keyburn, A.L., Kaldhusda...

New page

'''Unreleased structure'''

The entry 4i0n is ON HOLD

Authors: Yan, X., Porter, C.J., Hardy, S.P., Steer, D., Smith, A.I., Quinset, N., Hughes, V., Cheung, J.K., Keyburn, A.L., Kaldhusdal, M., Moore, R.J., Bannam, T.L., Whisstock, J.C., Rood, J.I.

Description: Pore forming protein