4i7h - Revision history

OCA at 11:51, 1 March 2024

OCA — Fri, 01 Mar 2024 11:51:18 GMT

←Older revision		Revision as of 11:51, 1 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4i7h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes_MGAS315 Streptococcus pyogenes MGAS315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I7H FirstGlance]. <br>		<table><tr><td colspan='2'>[[4i7h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes_MGAS315 Streptococcus pyogenes MGAS315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I7H FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i7h OCA], [https://pdbe.org/4i7h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i7h RCSB], [https://www.ebi.ac.uk/pdbsum/4i7h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i7h ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i7h OCA], [https://pdbe.org/4i7h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i7h RCSB], [https://www.ebi.ac.uk/pdbsum/4i7h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i7h ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/A0A0H2UT39_STRP3 A0A0H2UT39_STRP3]		[https://www.uniprot.org/uniprot/A0A0H2UT39_STRP3 A0A0H2UT39_STRP3]
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Regulation of oxidative stress responses by peroxide stress regulator (PerR) is critical for the in vivo fitness and virulence of group A Streptococcus (GAS). To elucidate the molecular mechanism of DNA binding, peroxide sensing, and gene regulation by PerR, we performed biochemical and structural characterization of PerR. Sequence-specific DNA binding by PerR does not require regulatory metal occupancy. However, metal binding promotes higher affinity PerR-DNA interactions. PerR metallated with iron directly senses peroxide stress and dissociates from operator sequences. The crystal structure revealed that PerR exists as a homodimer with two metal binding sites per subunit: a structural zinc site and a regulatory metal site that is occupied in the crystals by nickel. The regulatory metal-binding site in PerR involves a previously unobserved H-X-H motif located in its unique N-terminal extension. Mutational analysis of the regulatory site showed that the PerR metal ligands are involved in regulatory metal binding and integrity of this site is critical for GAS virulence. Interestingly, the metal-binding H-X-H motif is not present in the structurally characterized members of Ferric uptake regulator (Fur) family but fully conserved among PerR from the genus Streptococcus. Thus, it is likely that the PerR orthologs from streptococci share a common mechanism of metal binding, peroxide sensing, and gene regulation that is different from that of well-characterized PerR from Bacillus subtilis. Together, our findings provide key insights into the peroxide sensing and regulation of the oxidative stress adaptive responses by the streptococcal subfamily of PerR.
-
-	Crystal structure of peroxide stress regulator (PerR) from Streptococcus pyogenes provides functional insights into the mechanism of oxidative stress sensing.,Makthal N, Rastegari S, Sanson M, Ma Z, Olsen RJ, Helmann JD, Musser JM, Kumaraswami M J Biol Chem. 2013 May 3. PMID:23645680<ref>PMID:23645680</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4i7h" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 08:46, 9 November 2022

OCA — Wed, 09 Nov 2022 08:46:40 GMT

←Older revision		Revision as of 08:46, 9 November 2022
Line 3:		Line 3:
	<StructureSection load='4i7h' size='340' side='right'caption='[[4i7h]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4i7h' size='340' side='right'caption='[[4i7h]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4i7h]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Strp3 Strp3~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7H OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4I7H FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4i7h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes_MGAS315 Streptococcus pyogenes MGAS315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I7H FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">spf, SpyM3_0147 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=198466 STRP3])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i7h OCA], [https://pdbe.org/4i7h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i7h RCSB], [https://www.ebi.ac.uk/pdbsum/4i7h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i7h ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4i7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i7h OCA], [~~http~~://pdbe.org/4i7h PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4i7h RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4i7h PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4i7h ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A0H2UT39_STRP3 A0A0H2UT39_STRP3]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Strp3~~]]	+	[[Category: Streptococcus pyogenes MGAS315]]
-	[[Category: Kumaraswami, M]]	+	[[Category: Kumaraswami M]]
-	~~[[Category: Dna]]~~	+
-	~~[[Category: Metal homeostasis]]~~	+
-	~~[[Category: Oxidative stress sensing]]~~	+
-	~~[[Category: Transcription]]~~	+
-	~~[[Category: Winged helix-turn-helix motif~~]]	+

OCA at 11:59, 17 July 2019

OCA — Wed, 17 Jul 2019 11:59:28 GMT

←Older revision		Revision as of 11:59, 17 July 2019
Line 1:		Line 1:

	==Structural basis for peroxide sensing and gene regulation by PerR from Streptococcus pyogenes==		==Structural basis for peroxide sensing and gene regulation by PerR from Streptococcus pyogenes==
-	<StructureSection load='4i7h' size='340' side='right' caption='[[4i7h]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='4i7h' size='340' side='right'caption='[[4i7h]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4i7h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Strp3 Strp3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I7H FirstGlance]. <br>		<table><tr><td colspan='2'>[[4i7h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Strp3 Strp3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I7H FirstGlance]. <br>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Strp3]]		[[Category: Strp3]]
	[[Category: Kumaraswami, M]]		[[Category: Kumaraswami, M]]

OCA at 17:47, 5 August 2016

OCA — Fri, 05 Aug 2016 17:47:00 GMT

←Older revision		Revision as of 17:47, 5 August 2016
Line 1:		Line 1:
		+
	==Structural basis for peroxide sensing and gene regulation by PerR from Streptococcus pyogenes==		==Structural basis for peroxide sensing and gene regulation by PerR from Streptococcus pyogenes==
	<StructureSection load='4i7h' size='340' side='right' caption='[[4i7h]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4i7h' size='340' side='right' caption='[[4i7h]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4i7h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptococcus_pyogenes_mgas315 Streptococcus pyogenes mgas315~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I7H FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4i7h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Strp3 Strp3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I7H FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">spf, SpyM3_0147 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=198466 ~~Streptococcus pyogenes MGAS315~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">spf, SpyM3_0147 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=198466 STRP3])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i7h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4i7h RCSB], [http://www.ebi.ac.uk/pdbsum/4i7h PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i7h OCA], [http://pdbe.org/4i7h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4i7h RCSB], [http://www.ebi.ac.uk/pdbsum/4i7h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4i7h ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4i7h" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Streptococcus pyogenes mgas315~~]]	+	[[Category: Strp3]]
	[[Category: Kumaraswami, M]]		[[Category: Kumaraswami, M]]
	[[Category: Dna]]		[[Category: Dna]]

OCA at 12:51, 21 December 2014

OCA — Sun, 21 Dec 2014 12:51:50 GMT

←Older revision		Revision as of 12:51, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4i7h\| PDB=4i7h \| SCENE= }}~~	+	==Structural basis for peroxide sensing and gene regulation by PerR from Streptococcus pyogenes==
-	===Structural basis for peroxide sensing and gene regulation by PerR from Streptococcus pyogenes===	+	<StructureSection load='4i7h' size='340' side='right' caption='[[4i7h]], [[Resolution\|resolution]] 2.00Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23645680}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4i7h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes_mgas315 Streptococcus pyogenes mgas315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I7H FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">spf, SpyM3_0147 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=198466 Streptococcus pyogenes MGAS315])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i7h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4i7h RCSB], [http://www.ebi.ac.uk/pdbsum/4i7h PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Regulation of oxidative stress responses by peroxide stress regulator (PerR) is critical for the in vivo fitness and virulence of group A Streptococcus (GAS). To elucidate the molecular mechanism of DNA binding, peroxide sensing, and gene regulation by PerR, we performed biochemical and structural characterization of PerR. Sequence-specific DNA binding by PerR does not require regulatory metal occupancy. However, metal binding promotes higher affinity PerR-DNA interactions. PerR metallated with iron directly senses peroxide stress and dissociates from operator sequences. The crystal structure revealed that PerR exists as a homodimer with two metal binding sites per subunit: a structural zinc site and a regulatory metal site that is occupied in the crystals by nickel. The regulatory metal-binding site in PerR involves a previously unobserved H-X-H motif located in its unique N-terminal extension. Mutational analysis of the regulatory site showed that the PerR metal ligands are involved in regulatory metal binding and integrity of this site is critical for GAS virulence. Interestingly, the metal-binding H-X-H motif is not present in the structurally characterized members of Ferric uptake regulator (Fur) family but fully conserved among PerR from the genus Streptococcus. Thus, it is likely that the PerR orthologs from streptococci share a common mechanism of metal binding, peroxide sensing, and gene regulation that is different from that of well-characterized PerR from Bacillus subtilis. Together, our findings provide key insights into the peroxide sensing and regulation of the oxidative stress adaptive responses by the streptococcal subfamily of PerR.

-	~~==About this Structure==~~	+	Crystal structure of peroxide stress regulator (PerR) from Streptococcus pyogenes provides functional insights into the mechanism of oxidative stress sensing.,Makthal N, Rastegari S, Sanson M, Ma Z, Olsen RJ, Helmann JD, Musser JM, Kumaraswami M J Biol Chem. 2013 May 3. PMID:23645680<ref>PMID:23645680</ref>
-	~~[[4i7h]] is a 2 chain~~ structure ~~with sequence~~ from ~~[http://en.wikipedia.org/wiki/Streptococcus_pyogenes_mgas315~~ Streptococcus pyogenes ~~mgas315]~~. ~~Full crystallographic information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=4I7H OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:023645680</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Streptococcus pyogenes mgas315]]		[[Category: Streptococcus pyogenes mgas315]]
-	[[Category: Kumaraswami, M.]]	+	[[Category: Kumaraswami, M]]
	[[Category: Dna]]		[[Category: Dna]]
	[[Category: Metal homeostasis]]		[[Category: Metal homeostasis]]

OCA at 15:53, 19 June 2013

OCA — Wed, 19 Jun 2013 15:53:52 GMT

←Older revision		Revision as of 15:53, 19 June 2013
Line 1:		Line 1:
	{{STRUCTURE_4i7h\| PDB=4i7h \| SCENE= }}		{{STRUCTURE_4i7h\| PDB=4i7h \| SCENE= }}
	===Structural basis for peroxide sensing and gene regulation by PerR from Streptococcus pyogenes===		===Structural basis for peroxide sensing and gene regulation by PerR from Streptococcus pyogenes===
		+	{{ABSTRACT_PUBMED_23645680}}

	==About this Structure==		==About this Structure==
	[[4i7h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes_mgas315 Streptococcus pyogenes mgas315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7H OCA].		[[4i7h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes_mgas315 Streptococcus pyogenes mgas315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7H OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:023645680</ref><references group="xtra"/><references/>
	[[Category: Streptococcus pyogenes mgas315]]		[[Category: Streptococcus pyogenes mgas315]]
	[[Category: Kumaraswami, M.]]		[[Category: Kumaraswami, M.]]

OCA at 07:54, 8 May 2013

OCA — Wed, 08 May 2013 07:54:57 GMT

←Older revision		Revision as of 07:54, 8 May 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4i7h\| PDB=4i7h \| SCENE= }}
		+	===Structural basis for peroxide sensing and gene regulation by PerR from Streptococcus pyogenes===

-	~~The entry~~ 4i7h is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
-		+	[[4i7h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes_mgas315 Streptococcus pyogenes mgas315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7H OCA].
-	~~Authors~~: Kumaraswami, M.	+	[[Category: Streptococcus pyogenes mgas315]]
-		+	[[Category: Kumaraswami, M.]]
-	~~Description~~: ~~Structural basis for peroxide~~ sensing ~~and gene regulation by PerR from Streptococcus pyogenes~~	+	[[Category: Dna]]
		+	[[Category: Metal homeostasis]]
		+	[[Category: Oxidative stress sensing]]
		+	[[Category: Transcription]]
		+	[[Category: Winged helix-turn-helix motif]]

OCA at 13:22, 20 February 2013

OCA — Wed, 20 Feb 2013 13:22:46 GMT

←Older revision		Revision as of 13:22, 20 February 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4i7h is ON HOLD	+	The entry 4i7h is ON HOLD until Paper Publication

	Authors: Kumaraswami, M.		Authors: Kumaraswami, M.

	Description: Structural basis for peroxide sensing and gene regulation by PerR from Streptococcus pyogenes		Description: Structural basis for peroxide sensing and gene regulation by PerR from Streptococcus pyogenes

OCA at 08:53, 2 January 2013

OCA — Wed, 02 Jan 2013 08:53:23 GMT

←Older revision		Revision as of 08:53, 2 January 2013
Line 3:		Line 3:
	The entry 4i7h is ON HOLD		The entry 4i7h is ON HOLD

-	Authors: Kumaraswami. M.	+	Authors: Kumaraswami, M.

	Description: Structural basis for peroxide sensing and gene regulation by PerR from Streptococcus pyogenes		Description: Structural basis for peroxide sensing and gene regulation by PerR from Streptococcus pyogenes

OCA: Protected "4i7h" [edit=sysop:move=sysop]

OCA — Wed, 12 Dec 2012 20:49:28 GMT

Protected "4i7h" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:49, 12 December 2012