4i7s - Revision history

OCA at 15:16, 20 September 2023

OCA — Wed, 20 Sep 2023 15:16:59 GMT

←Older revision		Revision as of 15:16, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4i7s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I7S FirstGlance]. <br>		<table><tr><td colspan='2'>[[4i7s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I7S FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1DV:5-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE'>1DV</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.69Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1DV:5-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE'>1DV</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i7s OCA], [https://pdbe.org/4i7s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i7s RCSB], [https://www.ebi.ac.uk/pdbsum/4i7s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i7s ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i7s OCA], [https://pdbe.org/4i7s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i7s RCSB], [https://www.ebi.ac.uk/pdbsum/4i7s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i7s ProSAT]</span></td></tr>
	</table>		</table>

OCA at 08:47, 9 November 2022

OCA — Wed, 09 Nov 2022 08:47:04 GMT

←Older revision		Revision as of 08:47, 9 November 2022
Line 1:		Line 1:

	==T4 Lysozyme L99A/M102H with 3-trifluoromethyl-5-methyl pyrazole bound==		==T4 Lysozyme L99A/M102H with 3-trifluoromethyl-5-methyl pyrazole bound==
-	<StructureSection load='4i7s' size='340' side='right' caption='[[4i7s]], [[Resolution\|resolution]] 1.69Å' scene=''>	+	<StructureSection load='4i7s' size='340' side='right'caption='[[4i7s]], [[Resolution\|resolution]] 1.69Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4i7s]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Bpt4 Bpt4~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7S OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4I7S FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4i7s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I7S FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1DV:5-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE'>1DV</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1DV:5-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE'>1DV</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4e97\|4e97]], [[4ekp\|4ekp]], [[4ekq\|4ekq]], [[4ekr\|4ekr]], [[4eks\|4eks]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i7s OCA], [https://pdbe.org/4i7s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i7s RCSB], [https://www.ebi.ac.uk/pdbsum/4i7s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i7s ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>~~	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4i7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i7s OCA], [~~http~~://pdbe.org/4i7s PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4i7s RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4i7s PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4i7s ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~LYS_BPT4 LYS_BPT4~~]~~] Helps~~ to ~~release~~ the mature ~~phage~~ particles ~~from~~ the cell ~~wall by breaking~~ down the peptidoglycan.	+	[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 28:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bpt4~~]]	+	[[Category: Escherichia virus T4]]
-	[[Category: ~~Lysozyme~~]]	+	[[Category: Large Structures]]
-	[[Category: Merski, M]]	+	[[Category: Merski M]]
-	[[Category: Shoichet~~, B K]]~~	+	[[Category: Shoichet BK]]
-	~~[[Category: Hydrolase~~]]	+

OCA at 12:43, 5 August 2016

OCA — Fri, 05 Aug 2016 12:43:09 GMT

←Older revision		Revision as of 12:43, 5 August 2016
Line 1:		Line 1:
		+
	==T4 Lysozyme L99A/M102H with 3-trifluoromethyl-5-methyl pyrazole bound==		==T4 Lysozyme L99A/M102H with 3-trifluoromethyl-5-methyl pyrazole bound==
	<StructureSection load='4i7s' size='340' side='right' caption='[[4i7s]], [[Resolution\|resolution]] 1.69Å' scene=''>		<StructureSection load='4i7s' size='340' side='right' caption='[[4i7s]], [[Resolution\|resolution]] 1.69Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4i7s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Enterobacteria_phage_t4 Enterobacteria phage t4~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I7S FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4i7s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I7S FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1DV:5-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE'>1DV</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1DV:5-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE'>1DV</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4e97\|4e97]], [[4ekp\|4ekp]], [[4ekq\|4ekq]], [[4ekr\|4ekr]], [[4eks\|4eks]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4e97\|4e97]], [[4ekp\|4ekp]], [[4ekq\|4ekq]], [[4ekr\|4ekr]], [[4eks\|4eks]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 ~~Enterobacteria phage T4~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i7s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4i7s RCSB], [http://www.ebi.ac.uk/pdbsum/4i7s PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i7s OCA], [http://pdbe.org/4i7s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4i7s RCSB], [http://www.ebi.ac.uk/pdbsum/4i7s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4i7s ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4i7s" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 26:		Line 28:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Enterobacteria phage t4~~]]	+	[[Category: Bpt4]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Merski, M]]		[[Category: Merski, M]]
	[[Category: Shoichet, B K]]		[[Category: Shoichet, B K]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 02:33, 25 December 2014

OCA — Thu, 25 Dec 2014 02:33:23 GMT

←Older revision		Revision as of 02:33, 25 December 2014
Line 9:		Line 9:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i7s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4i7s RCSB], [http://www.ebi.ac.uk/pdbsum/4i7s PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i7s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4i7s RCSB], [http://www.ebi.ac.uk/pdbsum/4i7s PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/LYS_BPT4 LYS_BPT4]] Helps to release the mature phage particles from the cell wall by breaking down the peptidoglycan.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 13:04, 21 December 2014

OCA — Sun, 21 Dec 2014 13:04:07 GMT

←Older revision		Revision as of 13:04, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4i7s\| PDB=4i7s \| SCENE= }}~~	+	==T4 Lysozyme L99A/M102H with 3-trifluoromethyl-5-methyl pyrazole bound==
-	===T4 Lysozyme L99A/M102H with 3-trifluoromethyl-5-methyl pyrazole bound===	+	<StructureSection load='4i7s' size='340' side='right' caption='[[4i7s]], [[Resolution\|resolution]] 1.69Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23473072}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4i7s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I7S FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1DV:5-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE'>1DV</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4e97\|4e97]], [[4ekp\|4ekp]], [[4ekq\|4ekq]], [[4ekr\|4ekr]], [[4eks\|4eks]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 Enterobacteria phage T4])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i7s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4i7s RCSB], [http://www.ebi.ac.uk/pdbsum/4i7s PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Simplified model binding sites allow one to isolate entangled terms in molecular energy functions. Here, we investigate the effects on ligand recognition of the introduction of a histidine into a hydrophobic cavity in lysozyme. We docked 656040 molecules and tested 26 highly and nine poorly ranked. Twenty-one highly ranked molecules bound and five were false positives, while three poorly ranked molecules were false negatives. In the 16 X-ray complexes now known, the docking predictions overlaid well with the crystallographic results. Although ligand enrichment was high, the false negatives, the false positives, and the inability to rank order illuminated weaknesses in our scoring, particularly overweighed apolar and underweighted polar terms. Adjusting these led to new problems, reflecting the entangled nature of docking scoring functions. Changes in ligand affinity relative to other lysozyme cavities speak to the subtleties of molecular recognition even in these simple sites and to their relevance for testing different models of recognition.

-	~~==Function==~~	+	The Impact of Introducing a Histidine into an Apolar Cavity Site on Docking and Ligand Recognition.,Merski M, Shoichet BK J Med Chem. 2013 Mar 20. PMID:23473072<ref>PMID:23473072</ref>
-	~~[[http://www~~.~~uniprot~~.~~org~~/~~uniprot/LYS_BPT4 LYS_BPT4]] Helps to release the mature phage particles from the cell wall by breaking down the peptidoglycan.~~	+

-	==~~About this Structure~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[~~4i7s~~]] ~~is a 2 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7S OCA].~~	+	</div>
		+
		+	==See Also==
		+	*[[Lysozyme 3D structures\|Lysozyme 3D structures]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Enterobacteria phage t4]]		[[Category: Enterobacteria phage t4]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
-	[[Category: Merski, M.]]	+	[[Category: Merski, M]]
-	[[Category: Shoichet, B K.]]	+	[[Category: Shoichet, B K]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 08:48, 27 March 2013

OCA — Wed, 27 Mar 2013 08:48:17 GMT

←Older revision		Revision as of 08:48, 27 March 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4i7s\| PDB=4i7s \| SCENE= }}
		+	===T4 Lysozyme L99A/M102H with 3-trifluoromethyl-5-methyl pyrazole bound===
		+	{{ABSTRACT_PUBMED_23473072}}

-	~~The entry 4i7s is ON HOLD until Paper Publication~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/LYS_BPT4 LYS_BPT4]] Helps to release the mature phage particles from the cell wall by breaking down the peptidoglycan.

-	~~Authors~~: Merski, M., Shoichet, B.K.	+	==About this Structure==
-		+	[[4i7s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7S OCA].
-	~~Description~~: ~~T4 Lysozyme L99A/M102H with 3-trifluoromethyl-5-methyl pyrazole bound~~	+	[[Category: Enterobacteria phage t4]]
		+	[[Category: Lysozyme]]
		+	[[Category: Merski, M.]]
		+	[[Category: Shoichet, B K.]]
		+	[[Category: Hydrolase]]

OCA at 08:53, 2 January 2013

OCA — Wed, 02 Jan 2013 08:53:39 GMT

←Older revision		Revision as of 08:53, 2 January 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4i7s is ON HOLD	+	The entry 4i7s is ON HOLD until Paper Publication

	Authors: Merski, M., Shoichet, B.K.		Authors: Merski, M., Shoichet, B.K.

	Description: T4 Lysozyme L99A/M102H with 3-trifluoromethyl-5-methyl pyrazole bound		Description: T4 Lysozyme L99A/M102H with 3-trifluoromethyl-5-methyl pyrazole bound

OCA: Protected "4i7s" [edit=sysop:move=sysop]

OCA — Wed, 12 Dec 2012 20:49:49 GMT

Protected "4i7s" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:49, 12 December 2012

OCA: New page: '''Unreleased structure''' The entry 4i7s is ON HOLD Authors: Merski, M., Shoichet, B.K. Description: T4 Lysozyme L99A/M102H with 3-trifluoromethyl-5-methyl pyrazole bound

OCA — Wed, 12 Dec 2012 20:49:48 GMT

New page: '''Unreleased structure''' The entry 4i7s is ON HOLD Authors: Merski, M., Shoichet, B.K. Description: T4 Lysozyme L99A/M102H with 3-trifluoromethyl-5-methyl pyrazole bound

New page

'''Unreleased structure'''

The entry 4i7s is ON HOLD

Authors: Merski, M., Shoichet, B.K.

Description: T4 Lysozyme L99A/M102H with 3-trifluoromethyl-5-methyl pyrazole bound