4jgu - Revision history

OCA at 14:23, 8 November 2023

OCA — Wed, 08 Nov 2023 14:23:39 GMT

←Older revision		Revision as of 14:23, 8 November 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4jgu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Hathewaya_histolytica Hathewaya histolytica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JGU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JGU FirstGlance]. <br>		<table><tr><td colspan='2'>[[4jgu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Hathewaya_histolytica Hathewaya histolytica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JGU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JGU FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.42Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jgu OCA], [https://pdbe.org/4jgu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jgu RCSB], [https://www.ebi.ac.uk/pdbsum/4jgu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jgu ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jgu OCA], [https://pdbe.org/4jgu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jgu RCSB], [https://www.ebi.ac.uk/pdbsum/4jgu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jgu ProSAT]</span></td></tr>
	</table>		</table>

OCA at 11:12, 24 November 2022

OCA — Thu, 24 Nov 2022 11:12:24 GMT

←Older revision		Revision as of 11:12, 24 November 2022
Line 3:		Line 3:
	<StructureSection load='4jgu' size='340' side='right'caption='[[4jgu]], [[Resolution\|resolution]] 1.42Å' scene=''>		<StructureSection load='4jgu' size='340' side='right'caption='[[4jgu]], [[Resolution\|resolution]] 1.42Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4jgu]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_histolyticus"_weinberg_and_seguin_1916 "bacillus histolyticus" weinberg and seguin 1916~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JGU OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4JGU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4jgu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Hathewaya_histolytica Hathewaya histolytica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JGU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JGU FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y72\|2y72]], [[3jqu\|3jqu]], [[3js7\|3js7]], [[3jqw\|3jqw]], [[3jqx\|3jqx]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jgu OCA], [https://pdbe.org/4jgu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jgu RCSB], [https://www.ebi.ac.uk/pdbsum/4jgu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jgu ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">colH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1498 "Bacillus histolyticus" Weinberg and Seguin 1916])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4jgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jgu OCA], [~~http~~://pdbe.org/4jgu PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4jgu RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4jgu PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4jgu ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/COLH_HATHI COLH_HATHI] Clostridial collagenases are among the most efficient degraders of eukaryotic collagen known; saprophytes use collagen as a carbon source while pathogens additionally digest collagen to aid in host colonization. Has both tripeptidylcarboxypeptidase on Gly-X-Y and endopeptidase activities; the endopeptidase cuts within the triple helix region of collagen while tripeptidylcarboxypeptidase successively digests the exposed ends, thus clostridial collagenases can digest large sections of collagen (PubMed:3002446). The full-length protein has collagenase activity, while both the 116 kDa and 98 kDa forms act on gelatin (PubMed:7961400). In vitro digestion of soluble calf skin collagen fibrils requires both ColG and ColH; ColG forms missing the second collagen-binding domain is also synergistic with ColH, although their overall efficiency is decreased (PubMed:18374061, PubMed:22099748). Digestion of collagen requires Ca(2+) and is inhibited by EDTA (PubMed:9452493). The activator domain (residues 119-388) and catalytic subdomain (330-601) open and close around substrate allowing digestion when the protein is closed (PubMed:23703618).<ref>PMID:18374061</ref> <ref>PMID:18937627</ref> <ref>PMID:22099748</ref> <ref>PMID:23703618</ref> <ref>PMID:24125730</ref> <ref>PMID:28820255</ref> <ref>PMID:3002446</ref> <ref>PMID:7961400</ref> <ref>PMID:9452493</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus histolyticus weinberg and seguin 1916~~]]	+	[[Category: Hathewaya histolytica]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bauer, R]]	+	[[Category: Bauer R]]
-	[[Category: Matsushita, O]]	+	[[Category: Matsushita O]]
-	[[Category: Sakon, J]]	+	[[Category: Sakon J]]
-	~~[[Category: Beta-sandwich]]~~	+
-	~~[[Category: Calcium binding protein]]~~	+
-	~~[[Category: Ig-like fold]]~~	+
-	~~[[Category: Metal binding protein~~]]	+

OCA at 10:02, 25 December 2019

OCA — Wed, 25 Dec 2019 10:02:24 GMT

←Older revision		Revision as of 10:02, 25 December 2019
Line 1:		Line 1:

	==Crystal structure of Clostridium histolyticum ColH collagenase polycystic kidney-disease-like domain 2b at 1.4 Angstrom resolution in the presence of calcium==		==Crystal structure of Clostridium histolyticum ColH collagenase polycystic kidney-disease-like domain 2b at 1.4 Angstrom resolution in the presence of calcium==
-	<StructureSection load='4jgu' size='340' side='right' caption='[[4jgu]], [[Resolution\|resolution]] 1.42Å' scene=''>	+	<StructureSection load='4jgu' size='340' side='right'caption='[[4jgu]], [[Resolution\|resolution]] 1.42Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4jgu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_histolyticus"_weinberg_and_seguin_1916 "bacillus histolyticus" weinberg and seguin 1916]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JGU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JGU FirstGlance]. <br>		<table><tr><td colspan='2'>[[4jgu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_histolyticus"_weinberg_and_seguin_1916 "bacillus histolyticus" weinberg and seguin 1916]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JGU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JGU FirstGlance]. <br>
Line 9:		Line 9:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jgu OCA], [http://pdbe.org/4jgu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4jgu RCSB], [http://www.ebi.ac.uk/pdbsum/4jgu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4jgu ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jgu OCA], [http://pdbe.org/4jgu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4jgu RCSB], [http://www.ebi.ac.uk/pdbsum/4jgu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4jgu ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Clostridium histolyticum collagenases ColG and ColH are segmental enzymes that are thought to be activated by Ca(2+)-triggered domain reorientation to cause extensive tissue destruction. The collagenases consist of a collagenase module (s1), a variable number of polycystic kidney disease-like (PKD-like) domains (s2a and s2b in ColH and s2 in ColG) and a variable number of collagen-binding domains (s3 in ColH and s3a and s3b in ColG). The X-ray crystal structures of Ca(2+)-bound holo s2b (1.4 A resolution, R = 15.0%, Rfree = 19.1%) and holo s2a (1.9 A resolution, R = 16.3%, Rfree = 20.7%), as well as of Ca(2+)-free apo s2a (1.8 A resolution, R = 20.7%, Rfree = 27.2%) and two new forms of N-terminally truncated apo s2 (1.4 A resolution, R = 16.9%, Rfree = 21.2%; 1.6 A resolution, R = 16.2%, Rfree = 19.2%), are reported. The structurally similar PKD-like domains resemble the V-set Ig fold. In addition to a conserved beta-bulge, the PKD-like domains feature a second bulge that also changes the allegiance of the subsequent beta-strand. This beta-bulge and the genesis of a Ca(2+) pocket in the archaeal PKD-like domain suggest a close kinship between bacterial and archaeal PKD-like domains. Different surface properties and indications of different dynamics suggest unique roles for the PKD-like domains in ColG and in ColH. Surface aromatic residues found on ColH s2a-s2b, but not on ColG s2, may provide the weak interaction in the biphasic collagen-binding mode previously found in s2b-s3. B-factor analyses suggest that in the presence of Ca(2+) the midsection of s2 becomes more flexible but the midsections of s2a and s2b stay rigid. The different surface properties and dynamics of the domains suggest that the PKD-like domains of M9B bacterial collagenase can be grouped into either a ColG subset or a ColH subset. The conserved properties of PKD-like domains in ColG and in ColH include Ca(2+) binding. Conserved residues not only interact with Ca(2+), but also position the Ca(2+)-interacting water molecule. Ca(2+) aligns the N-terminal linker approximately parallel to the major axis of the domain. Ca(2+) binding also increases stability against heat and guanidine hydrochloride, and may improve the longevity in the extracellular matrix. The results of this study will further assist in developing collagen-targeting vehicles for various signal molecules.
		+
		+	Structures of three polycystic kidney disease-like domains from Clostridium histolyticum collagenases ColG and ColH.,Bauer R, Janowska K, Taylor K, Jordan B, Gann S, Janowski T, Latimer EC, Matsushita O, Sakon J Acta Crystallogr D Biol Crystallogr. 2015 Mar 1;71(Pt 3):565-77. doi:, 10.1107/S1399004714027722. Epub 2015 Feb 26. PMID:25760606<ref>PMID:25760606</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 4jgu" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
-	*[[Collagenase ~~(non-MMP)~~\|Collagenase ~~(non-MMP)~~]]	+	*[[Collagenase 3D structures\|Collagenase 3D structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Bacillus histolyticus weinberg and seguin 1916]]		[[Category: Bacillus histolyticus weinberg and seguin 1916]]
		+	[[Category: Large Structures]]
	[[Category: Bauer, R]]		[[Category: Bauer, R]]
	[[Category: Matsushita, O]]		[[Category: Matsushita, O]]

OCA at 17:00, 2 January 2017

OCA — Mon, 02 Jan 2017 17:00:11 GMT

←Older revision		Revision as of 17:00, 2 January 2017
Line 1:		Line 1:
		+
	==Crystal structure of Clostridium histolyticum ColH collagenase polycystic kidney-disease-like domain 2b at 1.4 Angstrom resolution in the presence of calcium==		==Crystal structure of Clostridium histolyticum ColH collagenase polycystic kidney-disease-like domain 2b at 1.4 Angstrom resolution in the presence of calcium==
	<StructureSection load='4jgu' size='340' side='right' caption='[[4jgu]], [[Resolution\|resolution]] 1.42Å' scene=''>		<StructureSection load='4jgu' size='340' side='right' caption='[[4jgu]], [[Resolution\|resolution]] 1.42Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y72\|2y72]], [[3jqu\|3jqu]], [[3js7\|3js7]], [[3jqw\|3jqw]], [[3jqx\|3jqx]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y72\|2y72]], [[3jqu\|3jqu]], [[3js7\|3js7]], [[3jqw\|3jqw]], [[3jqx\|3jqx]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">colH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1498 "Bacillus histolyticus" Weinberg and Seguin 1916])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">colH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1498 "Bacillus histolyticus" Weinberg and Seguin 1916])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jgu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jgu RCSB], [http://www.ebi.ac.uk/pdbsum/4jgu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jgu OCA], [http://pdbe.org/4jgu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4jgu RCSB], [http://www.ebi.ac.uk/pdbsum/4jgu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4jgu ProSAT]</span></td></tr>
	</table>		</table>

OCA at 12:25, 18 March 2015

OCA — Wed, 18 Mar 2015 12:25:48 GMT

←Older revision		Revision as of 12:25, 18 March 2015
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jgu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jgu RCSB], [http://www.ebi.ac.uk/pdbsum/4jgu PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jgu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jgu RCSB], [http://www.ebi.ac.uk/pdbsum/4jgu PDBsum]</span></td></tr>
	</table>		</table>
		+
		+	==See Also==
		+	*[[Collagenase (non-MMP)\|Collagenase (non-MMP)]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 08:06, 25 February 2015

OCA — Wed, 25 Feb 2015 08:06:21 GMT

←Older revision		Revision as of 08:06, 25 February 2015
Line 1:		Line 1:
-	==Crystal structure of Clostridium histolyticum ~~colH~~ collagenase ~~collagen~~-~~binding~~ domain 2b at 1.4 Angstrom resolution in presence of calcium==	+	==Crystal structure of Clostridium histolyticum ColH collagenase polycystic kidney-disease-like domain 2b at 1.4 Angstrom resolution in the presence of calcium==
	<StructureSection load='4jgu' size='340' side='right' caption='[[4jgu]], [[Resolution\|resolution]] 1.42Å' scene=''>		<StructureSection load='4jgu' size='340' side='right' caption='[[4jgu]], [[Resolution\|resolution]] 1.42Å' scene=''>
	== Structural highlights ==		== Structural highlights ==

OCA at 12:34, 4 January 2015

OCA — Sun, 04 Jan 2015 12:34:20 GMT

←Older revision		Revision as of 12:34, 4 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4jgu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_histolyticus"_weinberg_and_seguin_1916 "bacillus histolyticus" weinberg and seguin 1916]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JGU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JGU FirstGlance]. <br>		<table><tr><td colspan='2'>[[4jgu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_histolyticus"_weinberg_and_seguin_1916 "bacillus histolyticus" weinberg and seguin 1916]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JGU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JGU FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y72\|2y72]], [[3jqu\|3jqu]], [[3js7\|3js7]], [[3jqw\|3jqw]], [[3jqx\|3jqx]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y72\|2y72]], [[3jqu\|3jqu]], [[3js7\|3js7]], [[3jqw\|3jqw]], [[3jqx\|3jqx]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">colH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1498 "Bacillus histolyticus" Weinberg and Seguin 1916])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">colH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1498 "Bacillus histolyticus" Weinberg and Seguin 1916])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jgu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jgu RCSB], [http://www.ebi.ac.uk/pdbsum/4jgu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jgu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jgu RCSB], [http://www.ebi.ac.uk/pdbsum/4jgu PDBsum]</span></td></tr>
-	<table>	+	</table>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Bacillus histolyticus weinberg and seguin 1916]]		[[Category: Bacillus histolyticus weinberg and seguin 1916]]
-	[[Category: Bauer, R.]]	+	[[Category: Bauer, R]]
-	[[Category: Matsushita, O.]]	+	[[Category: Matsushita, O]]
-	[[Category: Sakon, J.]]	+	[[Category: Sakon, J]]
	[[Category: Beta-sandwich]]		[[Category: Beta-sandwich]]
	[[Category: Calcium binding protein]]		[[Category: Calcium binding protein]]
	[[Category: Ig-like fold]]		[[Category: Ig-like fold]]
	[[Category: Metal binding protein]]		[[Category: Metal binding protein]]

OCA at 12:09, 18 May 2014

OCA — Sun, 18 May 2014 12:09:30 GMT

←Older revision		Revision as of 12:09, 18 May 2014
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Crystal structure of Clostridium histolyticum colH collagenase collagen-binding domain 2b at 1.4 Angstrom resolution in presence of calcium==
-		+	<StructureSection load='4jgu' size='340' side='right' caption='[[4jgu]], [[Resolution\|resolution]] 1.42Å' scene=''>
-	~~The entry~~ 4jgu is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4jgu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_histolyticus"_weinberg_and_seguin_1916 "bacillus histolyticus" weinberg and seguin 1916]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JGU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JGU FirstGlance]. <br>
-	~~Authors~~: Bauer, R., Matsushita, O., Sakon, J.	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y72\|2y72]], [[3jqu\|3jqu]], [[3js7\|3js7]], [[3jqw\|3jqw]], [[3jqx\|3jqx]]</td></tr>
-	~~Description~~: ~~Crystal structure of Clostridium histolyticum colH collagenase collagen~~-binding ~~domain 2b at 1.4 Angstrom resolution in presence of calcium~~	+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">colH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1498 "Bacillus histolyticus" Weinberg and Seguin 1916])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jgu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jgu RCSB], [http://www.ebi.ac.uk/pdbsum/4jgu PDBsum]</span></td></tr>
		+	<table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Bacillus histolyticus weinberg and seguin 1916]]
		+	[[Category: Bauer, R.]]
		+	[[Category: Matsushita, O.]]
		+	[[Category: Sakon, J.]]
		+	[[Category: Beta-sandwich]]
		+	[[Category: Calcium binding protein]]
		+	[[Category: Ig-like fold]]
		+	[[Category: Metal binding protein]]

OCA at 08:16, 27 March 2013

OCA — Wed, 27 Mar 2013 08:16:58 GMT

←Older revision		Revision as of 08:16, 27 March 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4jgu is ON HOLD	+	The entry 4jgu is ON HOLD until Paper Publication

	Authors: Bauer, R., Matsushita, O., Sakon, J.		Authors: Bauer, R., Matsushita, O., Sakon, J.

	Description: Crystal structure of Clostridium histolyticum colH collagenase collagen-binding domain 2b at 1.4 Angstrom resolution in presence of calcium		Description: Crystal structure of Clostridium histolyticum colH collagenase collagen-binding domain 2b at 1.4 Angstrom resolution in presence of calcium

OCA at 16:19, 20 March 2013

OCA — Wed, 20 Mar 2013 16:19:18 GMT

←Older revision		Revision as of 16:19, 20 March 2013
Line 3:		Line 3:
	The entry 4jgu is ON HOLD		The entry 4jgu is ON HOLD

-	Authors: Bauer, R, Matsushita, O, Sakon, J	+	Authors: Bauer, R., Matsushita, O., Sakon, J.

	Description: Crystal structure of Clostridium histolyticum colH collagenase collagen-binding domain 2b at 1.4 Angstrom resolution in presence of calcium		Description: Crystal structure of Clostridium histolyticum colH collagenase collagen-binding domain 2b at 1.4 Angstrom resolution in presence of calcium