4jiu - Revision history

OCA at 08:53, 20 March 2024

OCA — Wed, 20 Mar 2024 08:53:52 GMT

←Older revision		Revision as of 08:53, 20 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4jiu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_abyssi_GE5 Pyrococcus abyssi GE5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JIU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JIU FirstGlance]. <br>		<table><tr><td colspan='2'>[[4jiu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_abyssi_GE5 Pyrococcus abyssi GE5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JIU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JIU FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.15Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jiu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jiu OCA], [https://pdbe.org/4jiu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jiu RCSB], [https://www.ebi.ac.uk/pdbsum/4jiu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jiu ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jiu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jiu OCA], [https://pdbe.org/4jiu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jiu RCSB], [https://www.ebi.ac.uk/pdbsum/4jiu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jiu ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/Q9V1Y2_PYRAB Q9V1Y2_PYRAB]		[https://www.uniprot.org/uniprot/Q9V1Y2_PYRAB Q9V1Y2_PYRAB]
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	In the search for structural models of integral-membrane metallopeptidases (MPs), we discovered three related proteins from thermophilic prokaryotes, which we grouped into a novel family called "minigluzincins." We determined the crystal structures of the zymogens of two of these (Pyrococcus abyssi proabylysin and Methanocaldococcus jannaschii projannalysin), which are soluble and, with approximately 100 residues, constitute the shortest structurally characterized MPs to date. Despite relevant sequence and structural similarity, the structures revealed two unique mechanisms of latency maintenance through the C-terminal segments previously unseen in MPs as follows: intramolecular, through an extended tail, in proabylysin, and crosswise intermolecular, through a helix swap, in projannalysin. In addition, structural and sequence comparisons revealed large similarity with MPs of the gluzincin tribe such as thermolysin, leukotriene A4 hydrolase relatives, and cowrins. Noteworthy, gluzincins mostly contain a glutamate as third characteristic zinc ligand, whereas minigluzincins have a histidine. Sequence and structural similarity further allowed us to ascertain that minigluzincins are very similar to the catalytic domains of integral membrane MPs of the MEROPS database families M48 and M56, such as FACE1, HtpX, Oma1, and BlaR1/MecR1, which are provided with trans-membrane helices flanking or inserted into a minigluzincin-like catalytic domain. In a time where structural biochemistry of integral-membrane proteins in general still faces formidable challenges, the minigluzincin soluble minimal scaffold may contribute to our understanding of the working mechanisms of these membrane MPs and to the design of novel inhibitors through structure-aided rational drug design approaches.
-
-	A novel family of soluble minimal scaffolds provides structural insight into the catalytic domains of integral membrane metallopeptidases.,Lopez-Pelegrin M, Cerda-Costa N, Martinez-Jimenez F, Cintas-Pedrola A, Canals A, Peinado JR, Marti-Renom MA, Lopez-Otin C, Arolas JL, Gomis-Ruth FX J Biol Chem. 2013 Jul 19;288(29):21279-94. doi: 10.1074/jbc.M113.476580. Epub, 2013 Jun 3. PMID:23733187<ref>PMID:23733187</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4jiu" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 11:15, 24 November 2022

OCA — Thu, 24 Nov 2022 11:15:29 GMT

←Older revision		Revision as of 11:15, 24 November 2022
Line 1:		Line 1:

	==Crystal structure of the metallopeptidase zymogen of Pyrococcus abyssi abylysin==		==Crystal structure of the metallopeptidase zymogen of Pyrococcus abyssi abylysin==
-	<StructureSection load='4jiu' size='340' side='right' caption='[[4jiu]], [[Resolution\|resolution]] 1.15Å' scene=''>	+	<StructureSection load='4jiu' size='340' side='right'caption='[[4jiu]], [[Resolution\|resolution]] 1.15Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4jiu]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Pyrab Pyrab~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JIU OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4JIU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4jiu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_abyssi_GE5 Pyrococcus abyssi GE5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JIU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JIU FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4jix\|4jix]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jiu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jiu OCA], [https://pdbe.org/4jiu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jiu RCSB], [https://www.ebi.ac.uk/pdbsum/4jiu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jiu ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PAB3079, PYRAB02920 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272844 PYRAB])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4jiu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jiu OCA], [~~http~~://pdbe.org/4jiu PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4jiu RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4jiu PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4jiu ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9V1Y2_PYRAB Q9V1Y2_PYRAB]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Pyrab~~]]	+	[[Category: Large Structures]]
-	[[Category: Arolas~~, J L~~]]	+	[[Category: Pyrococcus abyssi GE5]]
-	[[Category: Canals, A]]	+	[[Category: Arolas JL]]
-	[[Category: Cerda-Costa, N]]	+	[[Category: Canals A]]
-	[[Category: Cintas-Pedrola, A]]	+	[[Category: Cerda-Costa N]]
-	[[Category: Gomis-Ruth~~, F X~~]]	+	[[Category: Cintas-Pedrola A]]
-	[[Category: Lopez-Otin, C]]	+	[[Category: Gomis-Ruth FX]]
-	[[Category: Lopez-Pelegrin, M]]	+	[[Category: Lopez-Otin C]]
-	[[Category: Marti-Renom~~, M A~~]]	+	[[Category: Lopez-Pelegrin M]]
-	[[Category: Martinez-Jimenez, F]]	+	[[Category: Marti-Renom MA]]
-	[[Category: Peinado~~, J R]]~~	+	[[Category: Martinez-Jimenez F]]
-	~~[[Category: Hydrolase]]~~	+	[[Category: Peinado JR]]
-	~~[[Category: Metallopeptidase zymogen]]~~	+
-	~~[[Category: Minigluzincin~~]]	+

OCA at 16:09, 11 August 2016

OCA — Thu, 11 Aug 2016 16:09:06 GMT

←Older revision		Revision as of 16:09, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of the metallopeptidase zymogen of Pyrococcus abyssi abylysin==		==Crystal structure of the metallopeptidase zymogen of Pyrococcus abyssi abylysin==
	<StructureSection load='4jiu' size='340' side='right' caption='[[4jiu]], [[Resolution\|resolution]] 1.15Å' scene=''>		<StructureSection load='4jiu' size='340' side='right' caption='[[4jiu]], [[Resolution\|resolution]] 1.15Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4jiu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pyrococcus_abyssi_ge5 Pyrococcus abyssi ge5~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JIU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JIU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4jiu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrab Pyrab]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JIU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JIU FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4jix\|4jix]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4jix\|4jix]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PAB3079, PYRAB02920 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272844 ~~Pyrococcus abyssi GE5~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PAB3079, PYRAB02920 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272844 PYRAB])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jiu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jiu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jiu RCSB], [http://www.ebi.ac.uk/pdbsum/4jiu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jiu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jiu OCA], [http://pdbe.org/4jiu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4jiu RCSB], [http://www.ebi.ac.uk/pdbsum/4jiu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4jiu ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4jiu" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Pyrococcus abyssi ge5~~]]	+	[[Category: Pyrab]]
	[[Category: Arolas, J L]]		[[Category: Arolas, J L]]
	[[Category: Canals, A]]		[[Category: Canals, A]]

OCA at 12:40, 5 January 2015

OCA — Mon, 05 Jan 2015 12:40:39 GMT

←Older revision		Revision as of 12:40, 5 January 2015
Line 1:		Line 1:
-	~~{{STRUCTURE_4jiu\| PDB=4jiu \| SCENE= }}~~	+	==Crystal structure of the metallopeptidase zymogen of Pyrococcus abyssi abylysin==
-	===Crystal structure of the metallopeptidase zymogen of Pyrococcus abyssi abylysin===	+	<StructureSection load='4jiu' size='340' side='right' caption='[[4jiu]], [[Resolution\|resolution]] 1.15Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23733187}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4jiu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_abyssi_ge5 Pyrococcus abyssi ge5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JIU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JIU FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4jix\|4jix]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PAB3079, PYRAB02920 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272844 Pyrococcus abyssi GE5])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jiu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jiu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jiu RCSB], [http://www.ebi.ac.uk/pdbsum/4jiu PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In the search for structural models of integral-membrane metallopeptidases (MPs), we discovered three related proteins from thermophilic prokaryotes, which we grouped into a novel family called "minigluzincins." We determined the crystal structures of the zymogens of two of these (Pyrococcus abyssi proabylysin and Methanocaldococcus jannaschii projannalysin), which are soluble and, with approximately 100 residues, constitute the shortest structurally characterized MPs to date. Despite relevant sequence and structural similarity, the structures revealed two unique mechanisms of latency maintenance through the C-terminal segments previously unseen in MPs as follows: intramolecular, through an extended tail, in proabylysin, and crosswise intermolecular, through a helix swap, in projannalysin. In addition, structural and sequence comparisons revealed large similarity with MPs of the gluzincin tribe such as thermolysin, leukotriene A4 hydrolase relatives, and cowrins. Noteworthy, gluzincins mostly contain a glutamate as third characteristic zinc ligand, whereas minigluzincins have a histidine. Sequence and structural similarity further allowed us to ascertain that minigluzincins are very similar to the catalytic domains of integral membrane MPs of the MEROPS database families M48 and M56, such as FACE1, HtpX, Oma1, and BlaR1/MecR1, which are provided with trans-membrane helices flanking or inserted into a minigluzincin-like catalytic domain. In a time where structural biochemistry of integral-membrane proteins in general still faces formidable challenges, the minigluzincin soluble minimal scaffold may contribute to our understanding of the working mechanisms of these membrane MPs and to the design of novel inhibitors through structure-aided rational drug design approaches.

-	~~==About this Structure==~~	+	A novel family of soluble minimal scaffolds provides structural insight into the catalytic domains of integral membrane metallopeptidases.,Lopez-Pelegrin M, Cerda-Costa N, Martinez-Jimenez F, Cintas-Pedrola A, Canals A, Peinado JR, Marti-Renom MA, Lopez-Otin C, Arolas JL, Gomis-Ruth FX J Biol Chem. 2013 Jul 19;288(29):21279-94. doi: 10.1074/jbc.M113.476580. Epub, 2013 Jun 3. PMID:23733187<ref>PMID:23733187</ref>
-	~~[[4jiu]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Pyrococcus_abyssi_ge5 Pyrococcus abyssi ge5]~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.ac.~~il/oca-bin/ocashort?id=4JIU OCA]~~.	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:023733187</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Pyrococcus abyssi ge5]]		[[Category: Pyrococcus abyssi ge5]]
-	[[Category: Arolas, J L.]]	+	[[Category: Arolas, J L]]
-	[[Category: Canals, A.]]	+	[[Category: Canals, A]]
-	[[Category: Cerda-Costa, N.]]	+	[[Category: Cerda-Costa, N]]
-	[[Category: Cintas-Pedrola, A.]]	+	[[Category: Cintas-Pedrola, A]]
-	[[Category: Gomis-Ruth, F X.]]	+	[[Category: Gomis-Ruth, F X]]
-	[[Category: Lopez-Otin, C.]]	+	[[Category: Lopez-Otin, C]]
-	[[Category: Lopez-Pelegrin, M.]]	+	[[Category: Lopez-Pelegrin, M]]
-	[[Category: Marti-Renom, M A.]]	+	[[Category: Marti-Renom, M A]]
-	[[Category: Martinez-Jimenez, F.]]	+	[[Category: Martinez-Jimenez, F]]
-	[[Category: Peinado, J R.]]	+	[[Category: Peinado, J R]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Metallopeptidase zymogen]]		[[Category: Metallopeptidase zymogen]]
	[[Category: Minigluzincin]]		[[Category: Minigluzincin]]

OCA at 09:03, 4 September 2013

OCA — Wed, 04 Sep 2013 09:03:18 GMT

←Older revision		Revision as of 09:03, 4 September 2013
Line 1:		Line 1:
	{{STRUCTURE_4jiu\| PDB=4jiu \| SCENE= }}		{{STRUCTURE_4jiu\| PDB=4jiu \| SCENE= }}
	===Crystal structure of the metallopeptidase zymogen of Pyrococcus abyssi abylysin===		===Crystal structure of the metallopeptidase zymogen of Pyrococcus abyssi abylysin===
		+	{{ABSTRACT_PUBMED_23733187}}

	==About this Structure==		==About this Structure==
	[[4jiu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_abyssi_ge5 Pyrococcus abyssi ge5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JIU OCA].		[[4jiu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_abyssi_ge5 Pyrococcus abyssi ge5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JIU OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:023733187</ref><references group="xtra"/><references/>
	[[Category: Pyrococcus abyssi ge5]]		[[Category: Pyrococcus abyssi ge5]]
	[[Category: Arolas, J L.]]		[[Category: Arolas, J L.]]

OCA at 21:04, 19 June 2013

OCA — Wed, 19 Jun 2013 21:04:30 GMT

←Older revision		Revision as of 21:04, 19 June 2013
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_4jiu\| PDB=4jiu \| SCENE= }}
		+	===Crystal structure of the metallopeptidase zymogen of Pyrococcus abyssi abylysin===

-	~~The entry~~ 4jiu is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
-		+	[[4jiu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_abyssi_ge5 Pyrococcus abyssi ge5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JIU OCA].
-	~~Authors~~: ~~Lopez-Pelegrin~~, M., Cerda-Costa, N.~~, Martinez, F.,~~ Cintas, A., ~~Canals, A~~., ~~Peinado, J.R~~., Marti-Renom, M.A.~~, Lopez~~-~~Otin~~, C.~~, Arolas~~, J.~~L., Gomis-Ruth, F.X.~~	+	[[Category: Pyrococcus abyssi ge5]]
-		+	[[Category: Arolas, J L.]]
-	~~Description~~: ~~Crystal structure of a metallopeptidase~~ zymogen	+	[[Category: Canals, A.]]
		+	[[Category: Cerda-Costa, N.]]
		+	[[Category: Cintas-Pedrola, A.]]
		+	[[Category: Gomis-Ruth, F X.]]
		+	[[Category: Lopez-Otin, C.]]
		+	[[Category: Lopez-Pelegrin, M.]]
		+	[[Category: Marti-Renom, M A.]]
		+	[[Category: Martinez-Jimenez, F.]]
		+	[[Category: Peinado, J R.]]
		+	[[Category: Hydrolase]]
		+	[[Category: Metallopeptidase zymogen]]
		+	[[Category: Minigluzincin]]

OCA at 19:54, 17 April 2013

OCA — Wed, 17 Apr 2013 19:54:51 GMT

←Older revision		Revision as of 19:54, 17 April 2013
Line 3:		Line 3:
	The entry 4jiu is ON HOLD until Paper Publication		The entry 4jiu is ON HOLD until Paper Publication

-	Authors: Lopez-Pelegrin, M., Cerda-Costa, N., Martinez, F., Cintas, A., Canals, A., Peinado, J.R., Marti-Renom, M.A., Arolas, J.L., Gomis-Ruth, F.X~~., Lopez-Otin, C~~.	+	Authors: Lopez-Pelegrin, M., Cerda-Costa, N., Martinez, F., Cintas, A., Canals, A., Peinado, J.R., Marti-Renom, M.A., Lopez-Otin, C., Arolas, J.L., Gomis-Ruth, F.X.

	Description: Crystal structure of a metallopeptidase zymogen		Description: Crystal structure of a metallopeptidase zymogen

OCA at 00:54, 4 April 2013

OCA — Thu, 04 Apr 2013 00:54:36 GMT

←Older revision		Revision as of 00:54, 4 April 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4jiu is ON HOLD	+	The entry 4jiu is ON HOLD until Paper Publication

-	Authors: Lopez-Pelegrin, M., Cerda-Costa, N., Martinez, F., Cintas, A., Canals, A., Peinado, J.R., Marti-Renom, M.A., Arolas, J.L., Gomis-Ruth, F.X.	+	Authors: Lopez-Pelegrin, M., Cerda-Costa, N., Martinez, F., Cintas, A., Canals, A., Peinado, J.R., Marti-Renom, M.A., Arolas, J.L., Gomis-Ruth, F.X., Lopez-Otin, C.

	Description: Crystal structure of a metallopeptidase zymogen		Description: Crystal structure of a metallopeptidase zymogen

OCA: Protected "4jiu" [edit=sysop:move=sysop]

OCA — Wed, 13 Mar 2013 10:03:20 GMT

Protected "4jiu" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:03, 13 March 2013

OCA: New page: '''Unreleased structure''' The entry 4jiu is ON HOLD Authors: Lopez-Pelegrin, M., Cerda-Costa, N., Martinez, F., Cintas, A., Canals, A., Peinado, J.R., Marti-Renom, M.A., Arolas, J.L., ...

OCA — Wed, 13 Mar 2013 10:03:19 GMT

New page: '''Unreleased structure''' The entry 4jiu is ON HOLD Authors: Lopez-Pelegrin, M., Cerda-Costa, N., Martinez, F., Cintas, A., Canals, A., Peinado, J.R., Marti-Renom, M.A., Arolas, J.L., ...

New page

'''Unreleased structure'''

The entry 4jiu is ON HOLD

Authors: Lopez-Pelegrin, M., Cerda-Costa, N., Martinez, F., Cintas, A., Canals, A., Peinado, J.R., Marti-Renom, M.A., Arolas, J.L., Gomis-Ruth, F.X.

Description: Crystal structure of a metallopeptidase zymogen