4k3k - Revision history

OCA at 14:27, 8 November 2023

OCA — Wed, 08 Nov 2023 14:27:23 GMT

←Older revision		Revision as of 14:27, 8 November 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4k3k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K3K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K3K FirstGlance]. <br>		<table><tr><td colspan='2'>[[4k3k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K3K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K3K FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SFK:N-(4-METHYLPENTANOYL)-L-PHENYLALANINE'>SFK</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.85Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SFK:N-(4-METHYLPENTANOYL)-L-PHENYLALANINE'>SFK</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k3k OCA], [https://pdbe.org/4k3k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k3k RCSB], [https://www.ebi.ac.uk/pdbsum/4k3k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k3k ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k3k OCA], [https://pdbe.org/4k3k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k3k RCSB], [https://www.ebi.ac.uk/pdbsum/4k3k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k3k ProSAT]</span></td></tr>
	</table>		</table>
Line 18:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 4k3k" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4k3k" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[DNA polymerase 3D structures\|DNA polymerase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:38, 30 November 2022

OCA — Wed, 30 Nov 2022 11:38:35 GMT

←Older revision		Revision as of 11:38, 30 November 2022
Line 1:		Line 1:

	==E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid==		==E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid==
-	<StructureSection load='4k3k' size='340' side='right' caption='[[4k3k]], [[Resolution\|resolution]] 1.85Å' scene=''>	+	<StructureSection load='4k3k' size='340' side='right'caption='[[4k3k]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4k3k]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K3K OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4K3K FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4k3k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K3K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K3K FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SFK:N-(4-METHYLPENTANOYL)-L-PHENYLALANINE'>SFK</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SFK:N-(4-METHYLPENTANOYL)-L-PHENYLALANINE'>SFK</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1mmi\|1mmi]], [[4k3l\|4k3l]], [[4k3m\|4k3m]], [[4k3o\|4k3o]], [[4k3p\|4k3p]], [[4k3q\|4k3q]], [[4k3r\|4k3r]], [[4k3s\|4k3s]]</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k3k OCA], [https://pdbe.org/4k3k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k3k RCSB], [https://www.ebi.ac.uk/pdbsum/4k3k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k3k ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dnaN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>~~	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4k3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k3k OCA], [~~http~~://pdbe.org/4k3k PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4k3k RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4k3k PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4k3k ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/DPO3B_ECOLI DPO3B_ECOLI]] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.	+	[https://www.uniprot.org/uniprot/DPO3B_ECOLI DPO3B_ECOLI] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4k3k" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4k3k" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[DNA polymerase\|DNA polymerase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~DNA~~-~~directed DNA polymerase~~]]	+	[[Category: Escherichia coli K-12]]
-	[[Category: ~~Ecoli~~]]	+	[[Category: Large Structures]]
-	[[Category: Oakley~~, A J~~]]	+	[[Category: Oakley AJ]]
-	[[Category: Yin, Z]]	+	[[Category: Yin Z]]
-	~~[[Category: Dnan]]~~	+
-	~~[[Category: Poliii beta]]~~	+
-	~~[[Category: Sliding clamp]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 15:59, 5 August 2016

OCA — Fri, 05 Aug 2016 15:59:56 GMT

←Older revision		Revision as of 15:59, 5 August 2016
Line 1:		Line 1:
		+
	==E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid==		==E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid==
	<StructureSection load='4k3k' size='340' side='right' caption='[[4k3k]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='4k3k' size='340' side='right' caption='[[4k3k]], [[Resolution\|resolution]] 1.85Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dnaN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dnaN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k3k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k3k RCSB], [http://www.ebi.ac.uk/pdbsum/4k3k PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k3k OCA], [http://pdbe.org/4k3k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4k3k RCSB], [http://www.ebi.ac.uk/pdbsum/4k3k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4k3k ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4k3k" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 03:47, 25 December 2014

OCA — Thu, 25 Dec 2014 03:47:50 GMT

←Older revision		Revision as of 03:47, 25 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4k3k\| PDB=4k3k \| SCENE= }}~~	+	==E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid==
-	===E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid===	+	<StructureSection load='4k3k' size='340' side='right' caption='[[4k3k]], [[Resolution\|resolution]] 1.85Å' scene=''>
-	~~{{ABSTRACT_PUBMED_24090409}}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4k3k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K3K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K3K FirstGlance]. <br>
-	==Function==	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SFK:N-(4-METHYLPENTANOYL)-L-PHENYLALANINE'>SFK</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1mmi\|1mmi]], [[4k3l\|4k3l]], [[4k3m\|4k3m]], [[4k3o\|4k3o]], [[4k3p\|4k3p]], [[4k3q\|4k3q]], [[4k3r\|4k3r]], [[4k3s\|4k3s]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dnaN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k3k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k3k RCSB], [http://www.ebi.ac.uk/pdbsum/4k3k PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
	[[http://www.uniprot.org/uniprot/DPO3B_ECOLI DPO3B_ECOLI]] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.		[[http://www.uniprot.org/uniprot/DPO3B_ECOLI DPO3B_ECOLI]] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Protein-protein interactions based on linear motif (LM) recognition play roles in many cell regulatory processes. The E. coli sliding clamp is a protein mediator of replisome formation, which uses a common surface pocket composed of two subsites (I and II) to interact with LMs in multiple binding partners. A structural and thermodynamic dissection of sliding clamp-LM recognition has been performed, providing support for a sequential binding model. According to the model, a hydrophobic C-terminal LM dipeptide submotif acts as an anchor to establish initial contacts within subsite I, and this is followed by formation of a stabilizing hydrogen-bonding network between the flanking LM residues and subsite II. Differential solvation/desolvation during positioning of the submotifs is proposed as a driver for the sequential binding. Our model provides general insights into linear motif recognition and should guide the design of small-molecule inhibitors of the E. coli sliding clamp, an emerging antibacterial target.
		+
		+	Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp.,Yin Z, Kelso MJ, Beck JL, Oakley AJ J Med Chem. 2013 Nov 14;56(21):8665-73. doi: 10.1021/jm401118f. Epub 2013 Oct 22. PMID:24090409<ref>PMID:24090409</ref>

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[4k3k]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Ecoli Ecoli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4K3K OCA].~~	+	</div>

-	==~~Reference~~==	+	==See Also==
-	~~<ref group~~=~~"xtra">PMID:024090409</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	*[[DNA polymerase\|DNA polymerase]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: DNA-directed DNA polymerase]]		[[Category: DNA-directed DNA polymerase]]
	[[Category: Ecoli]]		[[Category: Ecoli]]
-	[[Category: Oakley, A J.]]	+	[[Category: Oakley, A J]]
-	[[Category: Yin, Z.]]	+	[[Category: Yin, Z]]
	[[Category: Dnan]]		[[Category: Dnan]]
	[[Category: Poliii beta]]		[[Category: Poliii beta]]
	[[Category: Sliding clamp]]		[[Category: Sliding clamp]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 07:01, 15 January 2014

OCA — Wed, 15 Jan 2014 07:01:56 GMT

←Older revision		Revision as of 07:01, 15 January 2014
Line 1:		Line 1:
	{{STRUCTURE_4k3k\| PDB=4k3k \| SCENE= }}		{{STRUCTURE_4k3k\| PDB=4k3k \| SCENE= }}
	===E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid===		===E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid===
		+	{{ABSTRACT_PUBMED_24090409}}

	==Function==		==Function==
Line 6:		Line 7:

	==About this Structure==		==About this Structure==
-	[[4k3k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli_k-12 Escherichia coli k-12~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K3K OCA].	+	[[4k3k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K3K OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:024090409</ref><references group="xtra"/><references/>
	[[Category: DNA-directed DNA polymerase]]		[[Category: DNA-directed DNA polymerase]]
-	[[Category: ~~Escherichia coli k-12~~]]	+	[[Category: Ecoli]]
	[[Category: Oakley, A J.]]		[[Category: Oakley, A J.]]
	[[Category: Yin, Z.]]		[[Category: Yin, Z.]]

OCA at 07:57, 2 May 2013

OCA — Thu, 02 May 2013 07:57:41 GMT

←Older revision		Revision as of 07:57, 2 May 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4k3k\| PDB=4k3k \| SCENE= }}
		+	===E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid===

-	The ~~entry 4k3k~~ is ~~ON HOLD~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/DPO3B_ECOLI DPO3B_ECOLI]] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.

-	~~Authors~~: ~~Yin, Z~~., Oakley, A.J.	+	==About this Structure==
-		+	[[4k3k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K3K OCA].
-	~~Description~~: E. ~~Coli sliding~~ clamp ~~in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid~~	+	[[Category: DNA-directed DNA polymerase]]
		+	[[Category: Escherichia coli k-12]]
		+	[[Category: Oakley, A J.]]
		+	[[Category: Yin, Z.]]
		+	[[Category: Dnan]]
		+	[[Category: Poliii beta]]
		+	[[Category: Sliding clamp]]
		+	[[Category: Transferase]]

OCA at 10:58, 24 April 2013

OCA — Wed, 24 Apr 2013 10:58:22 GMT

←Older revision		Revision as of 10:58, 24 April 2013
Line 3:		Line 3:
	The entry 4k3k is ON HOLD		The entry 4k3k is ON HOLD

-	Authors: Yin, Z., Oakley, A.J	+	Authors: Yin, Z., Oakley, A.J.

	Description: E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid		Description: E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid

OCA: Protected "4k3k" [edit=sysop:move=sysop]

OCA — Wed, 17 Apr 2013 20:07:57 GMT

Protected "4k3k" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:07, 17 April 2013

OCA: New page: '''Unreleased structure''' The entry 4k3k is ON HOLD Authors: Yin, Z., Oakley, A.J Description: E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid

OCA — Wed, 17 Apr 2013 20:07:55 GMT

New page: '''Unreleased structure''' The entry 4k3k is ON HOLD Authors: Yin, Z., Oakley, A.J Description: E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid

New page

'''Unreleased structure'''

The entry 4k3k is ON HOLD

Authors: Yin, Z., Oakley, A.J

Description: E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid