4k3r - Revision history

OCA at 14:27, 8 November 2023

OCA — Wed, 08 Nov 2023 14:27:40 GMT

←Older revision		Revision as of 14:27, 8 November 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4k3r]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K3R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K3R FirstGlance]. <br>		<table><tr><td colspan='2'>[[4k3r]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K3R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K3R FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.86Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k3r OCA], [https://pdbe.org/4k3r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k3r RCSB], [https://www.ebi.ac.uk/pdbsum/4k3r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k3r ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k3r OCA], [https://pdbe.org/4k3r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k3r RCSB], [https://www.ebi.ac.uk/pdbsum/4k3r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k3r ProSAT]</span></td></tr>
	</table>		</table>
Line 18:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 4k3r" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4k3r" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[DNA polymerase 3D structures\|DNA polymerase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:38, 30 November 2022

OCA — Wed, 30 Nov 2022 11:38:45 GMT

←Older revision		Revision as of 11:38, 30 November 2022
Line 1:		Line 1:

	==E. coli sliding clamp in complex with AcQLDLA==		==E. coli sliding clamp in complex with AcQLDLA==
-	<StructureSection load='4k3r' size='340' side='right' caption='[[4k3r]], [[Resolution\|resolution]] 1.86Å' scene=''>	+	<StructureSection load='4k3r' size='340' side='right'caption='[[4k3r]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4k3r]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K3R OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4K3R FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4k3r]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K3R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K3R FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k3r OCA], [https://pdbe.org/4k3r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k3r RCSB], [https://www.ebi.ac.uk/pdbsum/4k3r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k3r ProSAT]</span></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1mmi\|1mmi]], [[4k3k\|4k3k]], [[4k3l\|4k3l]], [[4k3m\|4k3m]], [[4k3o\|4k3o]], [[4k3p\|4k3p]], [[4k3q\|4k3q]], [[4k3s\|4k3s]]</td></tr>	+
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DnaN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>~~	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4k3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k3r OCA], [~~http~~://pdbe.org/4k3r PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4k3r RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4k3r PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4k3r ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/DPO3B_ECOLI DPO3B_ECOLI]] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.	+	[https://www.uniprot.org/uniprot/DPO3B_ECOLI DPO3B_ECOLI] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4k3r" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4k3r" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[DNA polymerase\|DNA polymerase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~DNA~~-~~directed DNA polymerase~~]]	+	[[Category: Escherichia coli K-12]]
-	[[Category: ~~Ecoli~~]]	+	[[Category: Large Structures]]
-	[[Category: Oakley~~, A J~~]]	+	[[Category: Oakley AJ]]
-	[[Category: Yin, Z]]	+	[[Category: Yin Z]]
-	~~[[Category: E. coli sliding clamp]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 19:17, 4 August 2016

OCA — Thu, 04 Aug 2016 19:17:39 GMT

←Older revision		Revision as of 19:17, 4 August 2016
Line 1:		Line 1:
		+
	==E. coli sliding clamp in complex with AcQLDLA==		==E. coli sliding clamp in complex with AcQLDLA==
	<StructureSection load='4k3r' size='340' side='right' caption='[[4k3r]], [[Resolution\|resolution]] 1.86Å' scene=''>		<StructureSection load='4k3r' size='340' side='right' caption='[[4k3r]], [[Resolution\|resolution]] 1.86Å' scene=''>
Line 8:		Line 9:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DnaN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DnaN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k3r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k3r RCSB], [http://www.ebi.ac.uk/pdbsum/4k3r PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k3r OCA], [http://pdbe.org/4k3r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4k3r RCSB], [http://www.ebi.ac.uk/pdbsum/4k3r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4k3r ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 20:		Line 21:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4k3r" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 12:20, 25 December 2014

OCA — Thu, 25 Dec 2014 12:20:08 GMT

←Older revision		Revision as of 12:20, 25 December 2014
Line 10:		Line 10:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k3r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k3r RCSB], [http://www.ebi.ac.uk/pdbsum/4k3r PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k3r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k3r RCSB], [http://www.ebi.ac.uk/pdbsum/4k3r PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/DPO3B_ECOLI DPO3B_ECOLI]] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 16:38, 21 December 2014

OCA — Sun, 21 Dec 2014 16:38:37 GMT

←Older revision		Revision as of 16:38, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4k3r\| PDB=4k3r \| SCENE= }}~~	+	==E. coli sliding clamp in complex with AcQLDLA==
-	===E. coli sliding clamp in complex with AcQLDLA===	+	<StructureSection load='4k3r' size='340' side='right' caption='[[4k3r]], [[Resolution\|resolution]] 1.86Å' scene=''>
-	~~{{ABSTRACT_PUBMED_24090409}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4k3r]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K3R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K3R FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1mmi\|1mmi]], [[4k3k\|4k3k]], [[4k3l\|4k3l]], [[4k3m\|4k3m]], [[4k3o\|4k3o]], [[4k3p\|4k3p]], [[4k3q\|4k3q]], [[4k3s\|4k3s]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DnaN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k3r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k3r RCSB], [http://www.ebi.ac.uk/pdbsum/4k3r PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Protein-protein interactions based on linear motif (LM) recognition play roles in many cell regulatory processes. The E. coli sliding clamp is a protein mediator of replisome formation, which uses a common surface pocket composed of two subsites (I and II) to interact with LMs in multiple binding partners. A structural and thermodynamic dissection of sliding clamp-LM recognition has been performed, providing support for a sequential binding model. According to the model, a hydrophobic C-terminal LM dipeptide submotif acts as an anchor to establish initial contacts within subsite I, and this is followed by formation of a stabilizing hydrogen-bonding network between the flanking LM residues and subsite II. Differential solvation/desolvation during positioning of the submotifs is proposed as a driver for the sequential binding. Our model provides general insights into linear motif recognition and should guide the design of small-molecule inhibitors of the E. coli sliding clamp, an emerging antibacterial target.

-	~~==Function==~~	+	Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp.,Yin Z, Kelso MJ, Beck JL, Oakley AJ J Med Chem. 2013 Nov 14;56(21):8665-73. doi: 10.1021/jm401118f. Epub 2013 Oct 22. PMID:24090409<ref>PMID:24090409</ref>
-	~~[[http://www.uniprot.org/uniprot/DPO3B_ECOLI DPO3B_ECOLI]] DNA polymerase III is a complex, multichain enzyme responsible for most~~ of the ~~replicative synthesis in bacteria~~. ~~This DNA polymerase also exhibits 3' to 5' exonuclease activity~~. ~~The beta chain is required for initiation of replication once it is clamped onto DNA~~, ~~it slides freely~~ (~~bidirectional and ATP-independent~~) ~~along duplex DNA~~.	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[4k3r]] is~~ a ~~3 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Ecoli Ecoli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4K3R OCA].~~	+	</div>

-	==~~Reference~~==	+	==See Also==
-	~~<ref group~~=~~"xtra">PMID:024090409</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	*[[DNA polymerase\|DNA polymerase]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: DNA-directed DNA polymerase]]		[[Category: DNA-directed DNA polymerase]]
	[[Category: Ecoli]]		[[Category: Ecoli]]
-	[[Category: Oakley, A J.]]	+	[[Category: Oakley, A J]]
-	[[Category: Yin, Z.]]	+	[[Category: Yin, Z]]
	[[Category: E. coli sliding clamp]]		[[Category: E. coli sliding clamp]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 07:02, 15 January 2014

OCA — Wed, 15 Jan 2014 07:02:41 GMT

←Older revision		Revision as of 07:02, 15 January 2014
Line 1:		Line 1:
	{{STRUCTURE_4k3r\| PDB=4k3r \| SCENE= }}		{{STRUCTURE_4k3r\| PDB=4k3r \| SCENE= }}
	===E. coli sliding clamp in complex with AcQLDLA===		===E. coli sliding clamp in complex with AcQLDLA===
		+	{{ABSTRACT_PUBMED_24090409}}

	==Function==		==Function==
Line 6:		Line 7:

	==About this Structure==		==About this Structure==
-	[[4k3r]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli_k-12 Escherichia coli k-12~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K3R OCA].	+	[[4k3r]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K3R OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:024090409</ref><references group="xtra"/><references/>
	[[Category: DNA-directed DNA polymerase]]		[[Category: DNA-directed DNA polymerase]]
-	[[Category: ~~Escherichia coli k-12~~]]	+	[[Category: Ecoli]]
	[[Category: Oakley, A J.]]		[[Category: Oakley, A J.]]
	[[Category: Yin, Z.]]		[[Category: Yin, Z.]]
	[[Category: E. coli sliding clamp]]		[[Category: E. coli sliding clamp]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 07:58, 2 May 2013

OCA — Thu, 02 May 2013 07:58:07 GMT

←Older revision		Revision as of 07:58, 2 May 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4k3r\| PDB=4k3r \| SCENE= }}
		+	===E. coli sliding clamp in complex with AcQLDLA===

-	The ~~entry 4k3r~~ is ~~ON HOLD~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/DPO3B_ECOLI DPO3B_ECOLI]] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.

-	~~Authors~~: ~~Yin, Z~~., Oakley, A.J.	+	==About this Structure==
-		+	[[4k3r]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K3R OCA].
-	~~Description~~: E. coli sliding clamp ~~in complex with AcQLDLA~~	+	[[Category: DNA-directed DNA polymerase]]
		+	[[Category: Escherichia coli k-12]]
		+	[[Category: Oakley, A J.]]
		+	[[Category: Yin, Z.]]
		+	[[Category: E. coli sliding clamp]]
		+	[[Category: Transferase]]

OCA: Protected "4k3r" [edit=sysop:move=sysop]

OCA — Wed, 17 Apr 2013 20:08:09 GMT

Protected "4k3r" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:08, 17 April 2013

OCA: New page: '''Unreleased structure''' The entry 4k3r is ON HOLD Authors: Yin, Z., Oakley, A.J. Description: E. coli sliding clamp in complex with AcQLDLA

OCA — Wed, 17 Apr 2013 20:08:08 GMT

New page: '''Unreleased structure''' The entry 4k3r is ON HOLD Authors: Yin, Z., Oakley, A.J. Description: E. coli sliding clamp in complex with AcQLDLA

New page

'''Unreleased structure'''

The entry 4k3r is ON HOLD

Authors: Yin, Z., Oakley, A.J.

Description: E. coli sliding clamp in complex with AcQLDLA