4kcw - Revision history

OCA at 12:10, 1 March 2024

OCA — Fri, 01 Mar 2024 12:10:11 GMT

←Older revision		Revision as of 12:10, 1 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4kcw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KCW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KCW FirstGlance]. <br>		<table><tr><td colspan='2'>[[4kcw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KCW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KCW FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FDP:FRUCTOSE-2,6-DIPHOSPHATE'>FDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FDP:FRUCTOSE-2,6-DIPHOSPHATE'>FDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kcw OCA], [https://pdbe.org/4kcw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kcw RCSB], [https://www.ebi.ac.uk/pdbsum/4kcw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kcw ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kcw OCA], [https://pdbe.org/4kcw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kcw RCSB], [https://www.ebi.ac.uk/pdbsum/4kcw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kcw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/KPYK1_TRYBB KPYK1_TRYBB]		[https://www.uniprot.org/uniprot/KPYK1_TRYBB KPYK1_TRYBB]
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The phosphotransfer mechanism of pyruvate kinases (PYKs) has been studied in detail, but the mechanism of the intrinsic decarboxylase reaction catalysed by PYKs is still unknown. 1H NMR was used in this work to follow oxaloacetate (OAA) decarboxylation by trypanosomatid and human PYKs confirming that the decarboxylase activity is conserved across distantly related species. Crystal structures of Trypanosoma brucei PYK (TbPYK) complexed with the product of the decarboxylase reaction (pyruvate), and a series of substrate analogues (D-malate, alpha-ketoglutarate and oxalate) show that the OAA analogues bind to the kinase active site with similar binding modes, confirming that both decarboxylase and kinase activities share a common site for substrate binding and catalysis. Decarboxylation of OAA as monitored by NMR for TbPYK is relatively slow with turn-over values of 0.86 s-1 and 1.47 s-1 in the absence and presence of fructose 2,6-bisphosphate (F26BP), respectively. Human M1PYK has a measured turn-over value of 0.50 s-1. The X-ray structures explain why the decarboxylation activity is specific for OAA and is not general for alpha-keto acid analogues. Conservation of the decarboxylase reaction across divergent species is a consequence of piggybacking on the conserved kinase mechanism which requires a stabilised enol intermediate.
-
-	Pyruvate kinases have an intrinsic and conserved decarboxylase activity.,Zhong W, Morgan HP, Nowicki MW, McNae IW, Yuan M, Bella J, Michels PA, Fothergill-Gilmore LA, Walkinshaw MD Biochem J. 2013 Dec 13. PMID:24328825<ref>PMID:24328825</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4kcw" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Pyruvate kinase 3D structures\|Pyruvate kinase 3D structures]]		*[[Pyruvate kinase 3D structures\|Pyruvate kinase 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 11:52, 30 November 2022

OCA — Wed, 30 Nov 2022 11:52:34 GMT

←Older revision		Revision as of 11:52, 30 November 2022
Line 1:		Line 1:

	==Pyruvate kinase (PYK) from Trypanosoma brucei soaked with oxalate==		==Pyruvate kinase (PYK) from Trypanosoma brucei soaked with oxalate==
-	<StructureSection load='4kcw' size='340' side='right' caption='[[4kcw]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='4kcw' size='340' side='right'caption='[[4kcw]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4kcw]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Trybb Trybb~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KCW OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4KCW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4kcw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KCW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KCW FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FDP:FRUCTOSE-2,6-DIPHOSPHATE'>FDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FDP:FRUCTOSE-2,6-DIPHOSPHATE'>FDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4kct\|4kct]], [[4kcu\|4kcu]], [[4kcv\|4kcv]], [[4hyv\|4hyv]], [[4hyw\|4hyw]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kcw OCA], [https://pdbe.org/4kcw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kcw RCSB], [https://www.ebi.ac.uk/pdbsum/4kcw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kcw ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PYK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5702 TRYBB])</td></tr>~~	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_kinase Pyruvate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.40 2.7.1.40] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4kcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kcw OCA], [~~http~~://pdbe.org/4kcw PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4kcw RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4kcw PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4kcw ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/KPYK1_TRYBB KPYK1_TRYBB]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 20:

	==See Also==		==See Also==
-	*[[Pyruvate ~~Kinase~~\|Pyruvate ~~Kinase~~]]	+	*[[Pyruvate kinase 3D structures\|Pyruvate kinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Pyruvate kinase~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Trybb~~]]	+	[[Category: Trypanosoma brucei brucei]]
-	[[Category: Fothergill-Gilmore~~, L A~~]]	+	[[Category: Fothergill-Gilmore LA]]
-	[[Category: McNae~~, I W~~]]	+	[[Category: McNae IW]]
-	[[Category: Michels~~, P A.M~~]]	+	[[Category: Michels PAM]]
-	[[Category: Morgan~~, H P~~]]	+	[[Category: Morgan HP]]
-	[[Category: Walkinshaw~~, M D~~]]	+	[[Category: Walkinshaw MD]]
-	[[Category: Zhong, W]]	+	[[Category: Zhong W]]
-	~~[[Category: Decarboxylase]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 10:43, 11 August 2016

OCA — Thu, 11 Aug 2016 10:43:16 GMT

←Older revision		Revision as of 10:43, 11 August 2016
Line 1:		Line 1:
		+
	==Pyruvate kinase (PYK) from Trypanosoma brucei soaked with oxalate==		==Pyruvate kinase (PYK) from Trypanosoma brucei soaked with oxalate==
	<StructureSection load='4kcw' size='340' side='right' caption='[[4kcw]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='4kcw' size='340' side='right' caption='[[4kcw]], [[Resolution\|resolution]] 2.50Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PYK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5702 TRYBB])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PYK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5702 TRYBB])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_kinase Pyruvate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.40 2.7.1.40] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_kinase Pyruvate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.40 2.7.1.40] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kcw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kcw RCSB], [http://www.ebi.ac.uk/pdbsum/4kcw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kcw OCA], [http://pdbe.org/4kcw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4kcw RCSB], [http://www.ebi.ac.uk/pdbsum/4kcw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4kcw ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4kcw" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 12:15, 4 January 2015

OCA — Sun, 04 Jan 2015 12:15:04 GMT

←Older revision		Revision as of 12:15, 4 January 2015
Line 1:		Line 1:
-	~~{{STRUCTURE_4kcw\| PDB=4kcw \| SCENE= }}~~	+	==Pyruvate kinase (PYK) from Trypanosoma brucei soaked with oxalate==
-	===Pyruvate kinase (PYK) from Trypanosoma brucei soaked with oxalate===	+	<StructureSection load='4kcw' size='340' side='right' caption='[[4kcw]], [[Resolution\|resolution]] 2.50Å' scene=''>
-	~~{{ABSTRACT_PUBMED_24328825}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4kcw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trybb Trybb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KCW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KCW FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FDP:FRUCTOSE-2,6-DIPHOSPHATE'>FDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4kct\|4kct]], [[4kcu\|4kcu]], [[4kcv\|4kcv]], [[4hyv\|4hyv]], [[4hyw\|4hyw]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PYK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5702 TRYBB])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_kinase Pyruvate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.40 2.7.1.40] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kcw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kcw RCSB], [http://www.ebi.ac.uk/pdbsum/4kcw PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The phosphotransfer mechanism of pyruvate kinases (PYKs) has been studied in detail, but the mechanism of the intrinsic decarboxylase reaction catalysed by PYKs is still unknown. 1H NMR was used in this work to follow oxaloacetate (OAA) decarboxylation by trypanosomatid and human PYKs confirming that the decarboxylase activity is conserved across distantly related species. Crystal structures of Trypanosoma brucei PYK (TbPYK) complexed with the product of the decarboxylase reaction (pyruvate), and a series of substrate analogues (D-malate, alpha-ketoglutarate and oxalate) show that the OAA analogues bind to the kinase active site with similar binding modes, confirming that both decarboxylase and kinase activities share a common site for substrate binding and catalysis. Decarboxylation of OAA as monitored by NMR for TbPYK is relatively slow with turn-over values of 0.86 s-1 and 1.47 s-1 in the absence and presence of fructose 2,6-bisphosphate (F26BP), respectively. Human M1PYK has a measured turn-over value of 0.50 s-1. The X-ray structures explain why the decarboxylation activity is specific for OAA and is not general for alpha-keto acid analogues. Conservation of the decarboxylase reaction across divergent species is a consequence of piggybacking on the conserved kinase mechanism which requires a stabilised enol intermediate.

-	~~==About this Structure==~~	+	Pyruvate kinases have an intrinsic and conserved decarboxylase activity.,Zhong W, Morgan HP, Nowicki MW, McNae IW, Yuan M, Bella J, Michels PA, Fothergill-Gilmore LA, Walkinshaw MD Biochem J. 2013 Dec 13. PMID:24328825<ref>PMID:24328825</ref>
-	~~[[4kcw]] is a 2 chain structure~~. ~~Full crystallographic information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=4KCW OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group~~=~~"xtra">PMID:024328825</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+
		+	==See Also==
		+	*[[Pyruvate Kinase\|Pyruvate Kinase]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Pyruvate kinase]]		[[Category: Pyruvate kinase]]
-	[[Category: Fothergill-Gilmore, L A.]]	+	[[Category: Trybb]]
-	[[Category: McNae, I W.]]	+	[[Category: Fothergill-Gilmore, L A]]
-	[[Category: Michels, P A.M.]]	+	[[Category: McNae, I W]]
-	[[Category: Morgan, H P.]]	+	[[Category: Michels, P A.M]]
-	[[Category: Walkinshaw, M D.]]	+	[[Category: Morgan, H P]]
-	[[Category: Zhong, W.]]	+	[[Category: Walkinshaw, M D]]
		+	[[Category: Zhong, W]]
	[[Category: Decarboxylase]]		[[Category: Decarboxylase]]
-	[[Category: Pyruvate kinase]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 10:38, 8 January 2014

OCA — Wed, 08 Jan 2014 10:38:04 GMT

←Older revision		Revision as of 10:38, 8 January 2014
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4kcw\| PDB=4kcw \| SCENE= }}
		+	===Pyruvate kinase (PYK) from Trypanosoma brucei soaked with oxalate===
		+	{{ABSTRACT_PUBMED_24328825}}

-	~~The entry~~ 4kcw is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
		+	[[4kcw]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KCW OCA].

-	~~Authors~~: ~~Zhong~~, W.~~, Morgan, H.P.,~~ McNae, I.W., Michels, P.A.M., ~~Fothergill-Gilmore, L.A~~., Walkinshaw, M.D.	+	==Reference==
-		+	<ref group="xtra">PMID:024328825</ref><references group="xtra"/><references/>
-	~~Description~~: Pyruvate kinase ~~(PYK) from Trypanosoma brucei soaked with oxalate~~	+	[[Category: Pyruvate kinase]]
		+	[[Category: Fothergill-Gilmore, L A.]]
		+	[[Category: McNae, I W.]]
		+	[[Category: Michels, P A.M.]]
		+	[[Category: Morgan, H P.]]
		+	[[Category: Walkinshaw, M D.]]
		+	[[Category: Zhong, W.]]
		+	[[Category: Decarboxylase]]
		+	[[Category: Pyruvate kinase]]
		+	[[Category: Transferase]]

OCA at 07:20, 8 May 2013

OCA — Wed, 08 May 2013 07:20:34 GMT

←Older revision		Revision as of 07:20, 8 May 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4kcw is ON HOLD	+	The entry 4kcw is ON HOLD until Paper Publication

	Authors: Zhong, W., Morgan, H.P., McNae, I.W., Michels, P.A.M., Fothergill-Gilmore, L.A., Walkinshaw, M.D.		Authors: Zhong, W., Morgan, H.P., McNae, I.W., Michels, P.A.M., Fothergill-Gilmore, L.A., Walkinshaw, M.D.

-	Description: Pyruvate kinase (PYK) from Trypanosoma brucei soaked with oxalate.	+	Description: Pyruvate kinase (PYK) from Trypanosoma brucei soaked with oxalate

OCA: Protected "4kcw" [edit=sysop:move=sysop]

OCA — Thu, 02 May 2013 07:16:43 GMT

Protected "4kcw" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:16, 2 May 2013

OCA: New page: '''Unreleased structure''' The entry 4kcw is ON HOLD Authors: Zhong, W., Morgan, H.P., McNae, I.W., Michels, P.A.M., Fothergill-Gilmore, L.A., Walkinshaw, M.D. Description: Pyruvate ki...

OCA — Thu, 02 May 2013 07:16:42 GMT

New page: '''Unreleased structure''' The entry 4kcw is ON HOLD Authors: Zhong, W., Morgan, H.P., McNae, I.W., Michels, P.A.M., Fothergill-Gilmore, L.A., Walkinshaw, M.D. Description: Pyruvate ki...

New page

'''Unreleased structure'''

The entry 4kcw is ON HOLD

Authors: Zhong, W., Morgan, H.P., McNae, I.W., Michels, P.A.M., Fothergill-Gilmore, L.A., Walkinshaw, M.D.

Description: Pyruvate kinase (PYK) from Trypanosoma brucei soaked with oxalate.