4kei - Revision history

OCA at 15:58, 20 September 2023

OCA — Wed, 20 Sep 2023 15:58:23 GMT

←Older revision		Revision as of 15:58, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4kei]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KEI FirstGlance]. <br>		<table><tr><td colspan='2'>[[4kei]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KEI FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kei OCA], [https://pdbe.org/4kei PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kei RCSB], [https://www.ebi.ac.uk/pdbsum/4kei PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kei ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.406Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kei OCA], [https://pdbe.org/4kei PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kei RCSB], [https://www.ebi.ac.uk/pdbsum/4kei PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kei ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 11:54, 30 November 2022

OCA — Wed, 30 Nov 2022 11:54:32 GMT

←Older revision		Revision as of 11:54, 30 November 2022
Line 1:		Line 1:

	==Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S==		==Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S==
-	<StructureSection load='4kei' size='340' side='right' caption='[[4kei]], [[Resolution\|resolution]] 2.41Å' scene=''>	+	<StructureSection load='4kei' size='340' side='right'caption='[[4kei]], [[Resolution\|resolution]] 2.41Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4kei]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Lk3_transgenic_mice Lk3 transgenic mice~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4KEI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4kei]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KEI FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3im5\|3im5]], [[3im6\|3im6]], [[3im7\|3im7]], [[3qr5\|3qr5]], [[4kej\|4kej]], [[4kek\|4kek]]</td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kei OCA], [https://pdbe.org/4kei PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kei RCSB], [https://www.ebi.ac.uk/pdbsum/4kei PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kei ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ryr2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4kei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kei OCA], [~~http~~://pdbe.org/4kei PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4kei RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4kei PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4kei ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/RYR2_MOUSE RYR2_MOUSE]] Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.<ref>PMID:10473538</ref> <ref>PMID:9628868</ref> <ref>PMID:21098440</ref> <ref>PMID:20431056</ref>	+	[https://www.uniprot.org/uniprot/RYR2_MOUSE RYR2_MOUSE] Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.<ref>PMID:10473538</ref> <ref>PMID:9628868</ref> <ref>PMID:21098440</ref> <ref>PMID:20431056</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 19:

	==See Also==		==See Also==
-	*[[Ryanodine receptor\|Ryanodine receptor]]	+	*[[Ryanodine receptor 3D structures\|Ryanodine receptor 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Lk3 transgenic mice~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Kimlicka, L~~]]	+	[[Category: Mus musculus]]
-	[[Category: ~~Petegem, F Van~~]]	+	[[Category: Kimlicka L]]
-	[[Category: ~~Ca2+ release]]~~	+	[[Category: Van Petegem F]]
-	~~[[Category: Er/sr membrane]]~~	+
-	~~[[Category: Ion channel]]~~	+
-	~~[[Category: Metal transport~~]]	+

OCA at 18:53, 5 August 2016

OCA — Fri, 05 Aug 2016 18:53:42 GMT

←Older revision		Revision as of 18:53, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S==		==Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S==
	<StructureSection load='4kei' size='340' side='right' caption='[[4kei]], [[Resolution\|resolution]] 2.41Å' scene=''>		<StructureSection load='4kei' size='340' side='right' caption='[[4kei]], [[Resolution\|resolution]] 2.41Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4kei]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mus_musculus Mus musculus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KEI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4kei]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KEI FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3im5\|3im5]], [[3im6\|3im6]], [[3im7\|3im7]], [[3qr5\|3qr5]], [[4kej\|4kej]], [[4kek\|4kek]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3im5\|3im5]], [[3im6\|3im6]], [[3im7\|3im7]], [[3qr5\|3qr5]], [[4kej\|4kej]], [[4kek\|4kek]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ryr2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 ~~Mus musculus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ryr2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kei OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kei RCSB], [http://www.ebi.ac.uk/pdbsum/4kei PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kei OCA], [http://pdbe.org/4kei PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4kei RCSB], [http://www.ebi.ac.uk/pdbsum/4kei PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4kei ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4kei" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Ryanodine receptor\|Ryanodine receptor]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Mus musculus~~]]	+	[[Category: Lk3 transgenic mice]]
	[[Category: Kimlicka, L]]		[[Category: Kimlicka, L]]
	[[Category: Petegem, F Van]]		[[Category: Petegem, F Van]]

OCA at 04:59, 25 December 2014

OCA — Thu, 25 Dec 2014 04:59:18 GMT

←Older revision		Revision as of 04:59, 25 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4kei\| PDB=4kei \| SCENE= }}~~	+	==Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S==
-	===Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S===	+	<StructureSection load='4kei' size='340' side='right' caption='[[4kei]], [[Resolution\|resolution]] 2.41Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23978697}}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4kei]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KEI FirstGlance]. <br>
-	==Function==	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3im5\|3im5]], [[3im6\|3im6]], [[3im7\|3im7]], [[3qr5\|3qr5]], [[4kej\|4kej]], [[4kek\|4kek]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ryr2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kei OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kei RCSB], [http://www.ebi.ac.uk/pdbsum/4kei PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
	[[http://www.uniprot.org/uniprot/RYR2_MOUSE RYR2_MOUSE]] Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.<ref>PMID:10473538</ref> <ref>PMID:9628868</ref> <ref>PMID:21098440</ref> <ref>PMID:20431056</ref>		[[http://www.uniprot.org/uniprot/RYR2_MOUSE RYR2_MOUSE]] Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.<ref>PMID:10473538</ref> <ref>PMID:9628868</ref> <ref>PMID:21098440</ref> <ref>PMID:20431056</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Ryanodine receptors (RyRs) are large tetrameric calcium (Ca2+) release channels found on the sarcoplasmic reticulum that respond to dihydropyridine receptor activity through a direct conformational interaction and/or indirect Ca2+ sensitivity, propagating sarcoplasmic reticulum luminal Ca2+ release in the process of excitation-contraction coupling. There are three human RyR subtypes, and several debilitating diseases are linked to heritable mutations in RyR1 and RyR2 including malignant hypothermia, central core disease, catecholaminergic polymorphic ventricular tachycardia (CPVT) and arrhythmogenic right ventricular dysplasia type 2 (ARVD2). Despite the recent appreciation that many disease-associated mutations within the N-terminal RyRABC domains (i.e., residues 1-559) are located in the putative interfaces mediating tetrameric channel assembly, the precise structural and dynamical consequences of the mutations are not well understood. We used solution nuclear magnetic resonance (NMR) spectroscopy and X-ray crystallography to examine the effect of ARVD2-associated (i.e., R176Q) and CPVT-associated [i.e., P164S, R169Q and delta exon 3 (Delta3)] mutations on the structure and dynamics of RyR2A. Our solution NMR data exposed a mobile alpha-helix, unique to type 2; further, this alpha2 helix rescues the beta-strand lost in RyR2A Delta3 but remains dynamic in the hot-spot loop (HS-loop) P164S, R169Q and R176Q mutant proteins. Docking of our X-ray crystal/NMR hybrid structure into the RyR1 cryo-electron microscopy map revealed that this RyR2A alpha2 helix is in close proximity to dense "columns" projecting toward the channel pore. This is in contrast to the HS-loop mutations that cause structural changes largely localized to the intersubunit interface between adjacent ABC domains. Taken together, our data suggest that ARVD2 and CPVT mutations have at least two distinct structural consequences linked to channel dysfunction: perturbation of the HS-loop (i.e., domain A):domain B intersubunit interface and disruption of the communication between the N-terminal region and the channel domain.

-	~~==About this Structure==~~	+	Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic alpha-Helix That Transitions to a beta-Strand in a Mutant Linked with a Heritable Cardiomyopathy.,Amador FJ, Kimlicka L, Stathopulos PB, Gasmi-Seabrook GM, Maclennan DH, Van Petegem F, Ikura M J Mol Biol. 2013 Aug 23. pii: S0022-2836(13)00535-4. doi:, 10.1016/j.jmb.2013.08.015. PMID:23978697<ref>PMID:23978697</ref>
-	~~[[4kei]] is~~ a ~~1 chain structure~~ with ~~sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Mus_musculus Mus musculus]~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.ac.~~il/oca-bin/ocashort?id=4KEI OCA]~~.	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:023978697</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Kimlicka, L.]]	+	[[Category: Kimlicka, L]]
-	[[Category: Petegem, F Van.]]	+	[[Category: Petegem, F Van]]
	[[Category: Ca2+ release]]		[[Category: Ca2+ release]]
	[[Category: Er/sr membrane]]		[[Category: Er/sr membrane]]
	[[Category: Ion channel]]		[[Category: Ion channel]]
	[[Category: Metal transport]]		[[Category: Metal transport]]

OCA at 05:05, 23 October 2013

OCA — Wed, 23 Oct 2013 05:05:45 GMT

←Older revision		Revision as of 05:05, 23 October 2013
Line 2:		Line 2:
	===Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S===		===Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S===
	{{ABSTRACT_PUBMED_23978697}}		{{ABSTRACT_PUBMED_23978697}}
		+
		+	==Function==
		+	[[http://www.uniprot.org/uniprot/RYR2_MOUSE RYR2_MOUSE]] Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.<ref>PMID:10473538</ref> <ref>PMID:9628868</ref> <ref>PMID:21098440</ref> <ref>PMID:20431056</ref>

	==About this Structure==		==About this Structure==

OCA at 04:02, 12 September 2013

OCA — Thu, 12 Sep 2013 04:02:24 GMT

←Older revision		Revision as of 04:02, 12 September 2013
Line 1:		Line 1:
	{{STRUCTURE_4kei\| PDB=4kei \| SCENE= }}		{{STRUCTURE_4kei\| PDB=4kei \| SCENE= }}
	===Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S===		===Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S===
		+	{{ABSTRACT_PUBMED_23978697}}

	==About this Structure==		==About this Structure==
	[[4kei]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEI OCA].		[[4kei]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEI OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:023978697</ref><references group="xtra"/><references/>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Kimlicka, L.]]		[[Category: Kimlicka, L.]]

OCA at 11:00, 4 September 2013

OCA — Wed, 04 Sep 2013 11:00:00 GMT

←Older revision		Revision as of 11:00, 4 September 2013
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_4kei\| PDB=4kei \| SCENE= }}
		+	===Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S===

-	~~The entry~~ 4kei is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
-		+	[[4kei]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEI OCA].
-	~~Authors~~: Kimlicka, L.~~, Van~~ Petegem, F.	+	[[Category: Mus musculus]]
-		+	[[Category: Kimlicka, L.]]
-	~~Description~~: ~~Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S~~	+	[[Category: Petegem, F Van.]]
		+	[[Category: Ca2+ release]]
		+	[[Category: Er/sr membrane]]
		+	[[Category: Ion channel]]
		+	[[Category: Metal transport]]

OCA at 11:35, 19 June 2013

OCA — Wed, 19 Jun 2013 11:35:07 GMT

←Older revision		Revision as of 11:35, 19 June 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4kei is ON HOLD	+	The entry 4kei is ON HOLD until Paper Publication

	Authors: Kimlicka, L., Van Petegem, F.		Authors: Kimlicka, L., Van Petegem, F.

	Description: Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S		Description: Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S

OCA: Protected "4kei" [edit=sysop:move=sysop]

OCA — Thu, 02 May 2013 07:18:46 GMT

Protected "4kei" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:18, 2 May 2013

OCA: New page: '''Unreleased structure''' The entry 4kei is ON HOLD Authors: Kimlicka, L., Van Petegem, F. Description: Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S

OCA — Thu, 02 May 2013 07:18:45 GMT

New page: '''Unreleased structure''' The entry 4kei is ON HOLD Authors: Kimlicka, L., Van Petegem, F. Description: Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S

New page

'''Unreleased structure'''

The entry 4kei is ON HOLD

Authors: Kimlicka, L., Van Petegem, F.

Description: Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S