4kfa - Revision history

OCA at 15:58, 20 September 2023

OCA — Wed, 20 Sep 2023 15:58:34 GMT

←Older revision		Revision as of 15:58, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4kfa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KFA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KFA FirstGlance]. <br>		<table><tr><td colspan='2'>[[4kfa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KFA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KFA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZOL:ZOLEDRONIC+ACID'>ZOL</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.98Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZOL:ZOLEDRONIC+ACID'>ZOL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kfa OCA], [https://pdbe.org/4kfa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kfa RCSB], [https://www.ebi.ac.uk/pdbsum/4kfa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kfa ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kfa OCA], [https://pdbe.org/4kfa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kfa RCSB], [https://www.ebi.ac.uk/pdbsum/4kfa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kfa ProSAT]</span></td></tr>
	</table>		</table>

OCA at 11:55, 30 November 2022

OCA — Wed, 30 Nov 2022 11:55:25 GMT

←Older revision		Revision as of 11:55, 30 November 2022
Line 1:		Line 1:

	==Crystal structure of human farnesyl pyrophosphate synthase (t201a mutant) complexed with mg and zoledronate==		==Crystal structure of human farnesyl pyrophosphate synthase (t201a mutant) complexed with mg and zoledronate==
-	<StructureSection load='4kfa' size='340' side='right' caption='[[4kfa]], [[Resolution\|resolution]] 1.98Å' scene=''>	+	<StructureSection load='4kfa' size='340' side='right'caption='[[4kfa]], [[Resolution\|resolution]] 1.98Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4kfa]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KFA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4KFA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4kfa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KFA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KFA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZOL:ZOLEDRONIC+ACID'>ZOL</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZOL:ZOLEDRONIC+ACID'>ZOL</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zw5\|1zw5]], [[2vf6\|2vf6]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kfa OCA], [https://pdbe.org/4kfa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kfa RCSB], [https://www.ebi.ac.uk/pdbsum/4kfa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kfa ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FDPS, FPS, KIAA1293 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4kfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kfa OCA], [~~http~~://pdbe.org/4kfa PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4kfa RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4kfa PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4kfa ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/FPPS_HUMAN FPPS_HUMAN]] Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.	+	[https://www.uniprot.org/uniprot/FPPS_HUMAN FPPS_HUMAN] Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.

	==See Also==		==See Also==
-	*[[Farnesyl diphosphate synthase\|Farnesyl diphosphate synthase]]	+	*[[Farnesyl diphosphate synthase 3D structures\|Farnesyl diphosphate synthase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: ~~Barnett, B L~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Muniz, J R.C~~]]	+	[[Category: Barnett BL]]
-	[[Category: ~~Tsoumpra, M K~~]]	+	[[Category: Muniz JRC]]
-	[[Category: ~~Walter, R L~~]]	+	[[Category: Tsoumpra MK]]
-	[[Category: ~~Bisphosphonate]]~~	+	[[Category: Walter RL]]
-	~~[[Category: Cholesterol synthesis]]~~	+
-	~~[[Category: Isopentyl pyrophosphate and dimethylallyl pyrophosphate]]~~	+
-	~~[[Category: Isoprene biosynthesis]]~~	+
-	~~[[Category: Isoprenoid pathway]]~~	+
-	~~[[Category: Lipid synthesis]]~~	+
-	~~[[Category: Steroid biosynthesis]]~~	+
-	~~[[Category: Transferase]]~~	+
-	~~[[Category: Transferase-transferase inhibitor complex~~]]	+

OCA at 21:45, 4 August 2016

OCA — Thu, 04 Aug 2016 21:45:14 GMT

←Older revision		Revision as of 21:45, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of human farnesyl pyrophosphate synthase (t201a mutant) complexed with mg and zoledronate==		==Crystal structure of human farnesyl pyrophosphate synthase (t201a mutant) complexed with mg and zoledronate==
	<StructureSection load='4kfa' size='340' side='right' caption='[[4kfa]], [[Resolution\|resolution]] 1.98Å' scene=''>		<StructureSection load='4kfa' size='340' side='right' caption='[[4kfa]], [[Resolution\|resolution]] 1.98Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zw5\|1zw5]], [[2vf6\|2vf6]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zw5\|1zw5]], [[2vf6\|2vf6]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FDPS, FPS, KIAA1293 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FDPS, FPS, KIAA1293 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kfa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kfa RCSB], [http://www.ebi.ac.uk/pdbsum/4kfa PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kfa OCA], [http://pdbe.org/4kfa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4kfa RCSB], [http://www.ebi.ac.uk/pdbsum/4kfa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4kfa ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/FPPS_HUMAN FPPS_HUMAN]] Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.		[[http://www.uniprot.org/uniprot/FPPS_HUMAN FPPS_HUMAN]] Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
		+
		+	==See Also==
		+	*[[Farnesyl diphosphate synthase\|Farnesyl diphosphate synthase]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 19:56, 24 December 2014

OCA — Wed, 24 Dec 2014 19:56:23 GMT

←Older revision		Revision as of 19:56, 24 December 2014
Line 2:		Line 2:
	<StructureSection load='4kfa' size='340' side='right' caption='[[4kfa]], [[Resolution\|resolution]] 1.98Å' scene=''>		<StructureSection load='4kfa' size='340' side='right' caption='[[4kfa]], [[Resolution\|resolution]] 1.98Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4kfa]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KFA OCA]. <br>	+	<table><tr><td colspan='2'>[[4kfa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KFA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KFA FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZOL:ZOLEDRONIC+ACID'>ZOL</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZOL:ZOLEDRONIC+ACID'>ZOL</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zw5\|1zw5]], [[2vf6\|2vf6]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zw5\|1zw5]], [[2vf6\|2vf6]]</td></tr>
-	<tr><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat">~~<span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase]~~, ~~with EC number~~ [http://www.~~brenda-enzymes~~.~~info~~/~~php~~/~~result_flat~~.~~php4~~?~~ecno~~=~~2.7.1.2 2.7.1.2~~] ~~</span>~~</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FDPS, FPS, KIAA1293 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kfa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kfa RCSB], [http://www.ebi.ac.uk/pdbsum/4kfa PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kfa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kfa RCSB], [http://www.ebi.ac.uk/pdbsum/4kfa PDBsum]</span></td></tr>
-	<table>	+	</table>
-	== ~~References~~ ==	+	== Function ==
-	~~<references~~/>	+	[[http://www.uniprot.org/uniprot/FPPS_HUMAN FPPS_HUMAN]] Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Barnett, B L.]]	+	[[Category: Human]]
-	[[Category: Muniz, J R.C.]]	+	[[Category: Barnett, B L]]
-	[[Category: Tsoumpra, M K.]]	+	[[Category: Muniz, J R.C]]
-	[[Category: Walter, R L.]]	+	[[Category: Tsoumpra, M K]]
		+	[[Category: Walter, R L]]
	[[Category: Bisphosphonate]]		[[Category: Bisphosphonate]]
	[[Category: Cholesterol synthesis]]		[[Category: Cholesterol synthesis]]

OCA at 09:25, 1 May 2014

OCA — Thu, 01 May 2014 09:25:57 GMT

←Older revision		Revision as of 09:25, 1 May 2014
Line 2:		Line 2:
	<StructureSection load='4kfa' size='340' side='right' caption='[[4kfa]], [[Resolution\|resolution]] 1.98Å' scene=''>		<StructureSection load='4kfa' size='340' side='right' caption='[[4kfa]], [[Resolution\|resolution]] 1.98Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	[[4kfa]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KFA OCA]. <br>	+	<table><tr><td colspan='2'>[[4kfa]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KFA OCA]. <br>
-	<b>[[Ligand\|Ligands:]]</b> <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZOL:ZOLEDRONIC+ACID'>ZOL</scene><br>	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZOL:ZOLEDRONIC+ACID'>ZOL</scene><br>
-	<b>[[Related_structure\|Related:]]</b> [[1zw5\|1zw5]], [[2vf6\|2vf6]]<br>	+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zw5\|1zw5]], [[2vf6\|2vf6]]</td></tr>
-	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>	+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
-	<b>Resources:</b> <span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kfa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kfa RCSB], [http://www.ebi.ac.uk/pdbsum/4kfa PDBsum]</span><br>	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kfa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kfa RCSB], [http://www.ebi.ac.uk/pdbsum/4kfa PDBsum]</span></td></tr>
		+	<table>
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:55, 30 April 2014

OCA — Wed, 30 Apr 2014 09:55:55 GMT

←Older revision		Revision as of 09:55, 30 April 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	[[4kfa]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KFA OCA]. <br>		[[4kfa]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KFA OCA]. <br>
-	<b>Related:</b> [[1zw5\|1zw5]], [[2vf6\|2vf6]]<br>	+	<b>[[Ligand\|Ligands:]]</b> <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZOL:ZOLEDRONIC+ACID'>ZOL</scene><br>
		+	<b>[[Related_structure\|Related:]]</b> [[1zw5\|1zw5]], [[2vf6\|2vf6]]<br>
	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>		<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
		+	<b>Resources:</b> <span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kfa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kfa RCSB], [http://www.ebi.ac.uk/pdbsum/4kfa PDBsum]</span><br>
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:59, 30 April 2014

OCA — Wed, 30 Apr 2014 07:59:57 GMT

←Older revision		Revision as of 07:59, 30 April 2014
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Crystal structure of human farnesyl pyrophosphate synthase (t201a mutant) complexed with mg and zoledronate==
-		+	<StructureSection load='4kfa' size='340' side='right' caption='[[4kfa]], [[Resolution\|resolution]] 1.98Å' scene=''>
-	~~The entry~~ 4kfa is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	[[4kfa]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KFA OCA]. <br>
-	~~Authors~~: ~~Barnett~~, B.L., ~~Tsoumpra, M~~.K., Muniz, J.R.C., Walter, R.L.	+	<b>Related:</b> [[1zw5\|1zw5]], [[2vf6\|2vf6]]<br>
-		+	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
-	~~Description~~: ~~Crystal structure of human farnesyl~~ pyrophosphate ~~synthase (t201a mutant) complexed with mg~~ and ~~zoledronate~~	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Barnett, B L.]]
		+	[[Category: Muniz, J R.C.]]
		+	[[Category: Tsoumpra, M K.]]
		+	[[Category: Walter, R L.]]
		+	[[Category: Bisphosphonate]]
		+	[[Category: Cholesterol synthesis]]
		+	[[Category: Isopentyl pyrophosphate and dimethylallyl pyrophosphate]]
		+	[[Category: Isoprene biosynthesis]]
		+	[[Category: Isoprenoid pathway]]
		+	[[Category: Lipid synthesis]]
		+	[[Category: Steroid biosynthesis]]
		+	[[Category: Transferase]]
		+	[[Category: Transferase-transferase inhibitor complex]]

OCA at 06:55, 16 May 2013

OCA — Thu, 16 May 2013 06:55:14 GMT

←Older revision		Revision as of 06:55, 16 May 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4kfa is ON HOLD	+	The entry 4kfa is ON HOLD until Paper Publication

	Authors: Barnett, B.L., Tsoumpra, M.K., Muniz, J.R.C., Walter, R.L.		Authors: Barnett, B.L., Tsoumpra, M.K., Muniz, J.R.C., Walter, R.L.

-	Description: Crystal structure of human farnesyl pyrophosphate synthase (t201a mutant) complexed with mg and ~~biphosphonate~~	+	Description: Crystal structure of human farnesyl pyrophosphate synthase (t201a mutant) complexed with mg and zoledronate

OCA: Protected "4kfa" [edit=sysop:move=sysop]

OCA — Wed, 08 May 2013 07:21:37 GMT

Protected "4kfa" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:21, 8 May 2013

OCA: New page: '''Unreleased structure''' The entry 4kfa is ON HOLD Authors: Barnett, B.L., Tsoumpra, M.K., Muniz, J.R.C., Walter, R.L. Description: Crystal structure of human farnesyl pyrophosphate ...

OCA — Wed, 08 May 2013 07:21:35 GMT

New page: '''Unreleased structure''' The entry 4kfa is ON HOLD Authors: Barnett, B.L., Tsoumpra, M.K., Muniz, J.R.C., Walter, R.L. Description: Crystal structure of human farnesyl pyrophosphate ...

New page

'''Unreleased structure'''

The entry 4kfa is ON HOLD

Authors: Barnett, B.L., Tsoumpra, M.K., Muniz, J.R.C., Walter, R.L.

Description: Crystal structure of human farnesyl pyrophosphate synthase (t201a mutant) complexed with mg and biphosphonate