4khy - Revision history

OCA at 15:59, 20 September 2023

OCA — Wed, 20 Sep 2023 15:59:52 GMT

←Older revision		Revision as of 15:59, 20 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4khy]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_RB69 Escherichia phage RB69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KHY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KHY FirstGlance]. <br>		<table><tr><td colspan='2'>[[4khy]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_RB69 Escherichia phage RB69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KHY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KHY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.25Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4khy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4khy OCA], [https://pdbe.org/4khy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4khy RCSB], [https://www.ebi.ac.uk/pdbsum/4khy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4khy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4khy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4khy OCA], [https://pdbe.org/4khy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4khy RCSB], [https://www.ebi.ac.uk/pdbsum/4khy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4khy ProSAT]</span></td></tr>
	</table>		</table>
Line 18:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 4khy" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4khy" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[DNA polymerase 3D structures\|DNA polymerase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:53, 7 December 2022

OCA — Wed, 07 Dec 2022 08:53:17 GMT

←Older revision		Revision as of 08:53, 7 December 2022
Line 1:		Line 1:

	==Ternary complex of rb69 mutant L415F with ribonucleotide at -3 position==		==Ternary complex of rb69 mutant L415F with ribonucleotide at -3 position==
-	<StructureSection load='4khy' size='340' side='right' caption='[[4khy]], [[Resolution\|resolution]] 2.25Å' scene=''>	+	<StructureSection load='4khy' size='340' side='right'caption='[[4khy]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4khy]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Bpr69 Bpr69~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KHY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4KHY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4khy]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_RB69 Escherichia phage RB69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KHY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KHY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4khq\|4khq]], [[4khs\|4khs]], [[4khu\|4khu]], [[4khw\|4khw]], [[4ki4\|4ki4]], [[4ki6\|4ki6]]</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4khy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4khy OCA], [https://pdbe.org/4khy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4khy RCSB], [https://www.ebi.ac.uk/pdbsum/4khy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4khy ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">43 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12353 BPR69])</td></tr>~~	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4khy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4khy OCA], [~~http~~://pdbe.org/4khy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4khy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4khy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4khy ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/DPOL_BPR69 DPOL_BPR69]] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.	+	[https://www.uniprot.org/uniprot/DPOL_BPR69 DPOL_BPR69] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4khy" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4khy" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[DNA polymerase\|DNA polymerase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bpr69~~]]	+	[[Category: Escherichia phage RB69]]
-	[[Category: ~~DNA-directed DNA polymerase~~]]	+	[[Category: Large Structures]]
-	[[Category: Clausen~~, A R~~]]	+	[[Category: Clausen AR]]
-	[[Category: Pedersen~~, L C]]~~	+	[[Category: Pedersen LC]]
-	~~[[Category: Ribonucleotide]]~~	+
-	~~[[Category: Transferase-dna complex~~]]	+

OCA at 18:31, 5 August 2016

OCA — Fri, 05 Aug 2016 18:31:14 GMT

←Older revision		Revision as of 18:31, 5 August 2016
Line 1:		Line 1:
		+
	==Ternary complex of rb69 mutant L415F with ribonucleotide at -3 position==		==Ternary complex of rb69 mutant L415F with ribonucleotide at -3 position==
	<StructureSection load='4khy' size='340' side='right' caption='[[4khy]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='4khy' size='340' side='right' caption='[[4khy]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4khy]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Enterobacteria_phage_rb69 Enterobacteria phage rb69~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KHY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KHY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4khy]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpr69 Bpr69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KHY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KHY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4khq\|4khq]], [[4khs\|4khs]], [[4khu\|4khu]], [[4khw\|4khw]], [[4ki4\|4ki4]], [[4ki6\|4ki6]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4khq\|4khq]], [[4khs\|4khs]], [[4khu\|4khu]], [[4khw\|4khw]], [[4ki4\|4ki4]], [[4ki6\|4ki6]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">43 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12353 ~~Enterobacteria phage RB69~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">43 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12353 BPR69])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4khy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4khy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4khy RCSB], [http://www.ebi.ac.uk/pdbsum/4khy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4khy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4khy OCA], [http://pdbe.org/4khy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4khy RCSB], [http://www.ebi.ac.uk/pdbsum/4khy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4khy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4khy" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 26:		Line 28:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bpr69]]
	[[Category: DNA-directed DNA polymerase]]		[[Category: DNA-directed DNA polymerase]]
-	[[Category: Enterobacteria phage rb69]]
	[[Category: Clausen, A R]]		[[Category: Clausen, A R]]
	[[Category: Pedersen, L C]]		[[Category: Pedersen, L C]]
	[[Category: Ribonucleotide]]		[[Category: Ribonucleotide]]
	[[Category: Transferase-dna complex]]		[[Category: Transferase-dna complex]]

OCA at 04:50, 25 December 2014

OCA — Thu, 25 Dec 2014 04:50:19 GMT

←Older revision		Revision as of 04:50, 25 December 2014
Line 9:		Line 9:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4khy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4khy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4khy RCSB], [http://www.ebi.ac.uk/pdbsum/4khy PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4khy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4khy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4khy RCSB], [http://www.ebi.ac.uk/pdbsum/4khy PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/DPOL_BPR69 DPOL_BPR69]] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 14:38, 21 December 2014

OCA — Sun, 21 Dec 2014 14:38:51 GMT

←Older revision		Revision as of 14:38, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4khy\| PDB=4khy \| SCENE= }}~~	+	==Ternary complex of rb69 mutant L415F with ribonucleotide at -3 position==
-	===Ternary complex of rb69 mutant L415F with ribonucleotide at -3 position===	+	<StructureSection load='4khy' size='340' side='right' caption='[[4khy]], [[Resolution\|resolution]] 2.25Å' scene=''>
-	~~{{ABSTRACT_PUBMED_24082122}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4khy]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_rb69 Enterobacteria phage rb69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KHY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KHY FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4khq\|4khq]], [[4khs\|4khs]], [[4khu\|4khu]], [[4khw\|4khw]], [[4ki4\|4ki4]], [[4ki6\|4ki6]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">43 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12353 Enterobacteria phage RB69])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4khy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4khy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4khy RCSB], [http://www.ebi.ac.uk/pdbsum/4khy PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Ribonucleotides are frequently incorporated into DNA during replication, they are normally removed, and failure to remove them results in replication stress. This stress correlates with DNA polymerase (Pol) stalling during bypass of ribonucleotides in DNA templates. Here we demonstrate that stalling by yeast replicative Pols delta and epsilon increases as the number of consecutive template ribonucleotides increases from one to four. The homologous bacteriophage RB69 Pol also stalls during ribonucleotide bypass, with a pattern most similar to that of Pol epsilon. Crystal structures of an exonuclease-deficient variant of RB69 Pol corresponding to multiple steps in single ribonucleotide bypass reveal that increased stalling is associated with displacement of Tyr391 and an unpreferred C2'-endo conformation for the ribose. Even less efficient bypass of two consecutive ribonucleotides in DNA correlates with similar movements of Tyr391 and displacement of one of the ribonucleotides along with the primer-strand DNA backbone. These structure-function studies have implications for cellular signaling by ribonucleotides, and they may be relevant to replication stress in cells defective in ribonucleotide excision repair, including humans suffering from autoimmune disease associated with RNase H2 defects.

-	~~==Function==~~	+	Structure-function analysis of ribonucleotide bypass by B family DNA replicases.,Clausen AR, Murray MS, Passer AR, Pedersen LC, Kunkel TA Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16802-7. doi:, 10.1073/pnas.1309119110. Epub 2013 Sep 30. PMID:24082122<ref>PMID:24082122</ref>
-	~~[[http://www~~.~~uniprot~~.~~org/uniprot/DPOL_BPR69 DPOL_BPR69]] This polymerase possesses two enzymatic activities: DNA synthesis~~ (~~polymerase~~) ~~and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'~~-~~direction~~.	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[4khy]] is~~ a ~~3 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Enterobacteria_phage_rb69 Enterobacteria phage rb69]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4KHY OCA].~~	+	</div>

-	==~~Reference~~==	+	==See Also==
-	~~<ref group~~=~~"xtra">PMID:024082122</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	*[[DNA polymerase\|DNA polymerase]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: DNA-directed DNA polymerase]]		[[Category: DNA-directed DNA polymerase]]
	[[Category: Enterobacteria phage rb69]]		[[Category: Enterobacteria phage rb69]]
-	[[Category: Clausen, A R.]]	+	[[Category: Clausen, A R]]
-	[[Category: Pedersen, L C.]]	+	[[Category: Pedersen, L C]]
	[[Category: Ribonucleotide]]		[[Category: Ribonucleotide]]
	[[Category: Transferase-dna complex]]		[[Category: Transferase-dna complex]]

OCA at 08:25, 30 October 2013

OCA — Wed, 30 Oct 2013 08:25:41 GMT

←Older revision		Revision as of 08:25, 30 October 2013
Line 1:		Line 1:
	{{STRUCTURE_4khy\| PDB=4khy \| SCENE= }}		{{STRUCTURE_4khy\| PDB=4khy \| SCENE= }}
	===Ternary complex of rb69 mutant L415F with ribonucleotide at -3 position===		===Ternary complex of rb69 mutant L415F with ribonucleotide at -3 position===
		+	{{ABSTRACT_PUBMED_24082122}}

	==Function==		==Function==
Line 7:		Line 8:
	==About this Structure==		==About this Structure==
	[[4khy]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_rb69 Enterobacteria phage rb69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KHY OCA].		[[4khy]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_rb69 Enterobacteria phage rb69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KHY OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:024082122</ref><references group="xtra"/><references/>
	[[Category: DNA-directed DNA polymerase]]		[[Category: DNA-directed DNA polymerase]]
	[[Category: Enterobacteria phage rb69]]		[[Category: Enterobacteria phage rb69]]

OCA at 06:40, 10 October 2013

OCA — Thu, 10 Oct 2013 06:40:13 GMT

←Older revision		Revision as of 06:40, 10 October 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4khy\| PDB=4khy \| SCENE= }}
		+	===Ternary complex of rb69 mutant L415F with ribonucleotide at -3 position===

-	~~The entry 4khy is ON HOLD until Paper Publication~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/DPOL_BPR69 DPOL_BPR69]] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.

-	~~Authors~~: Clausen, A.R., Pedersen, L.C.	+	==About this Structure==
-		+	[[4khy]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_rb69 Enterobacteria phage rb69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KHY OCA].
-	~~Description~~: ~~Ternary complex of rb69 mutant L415F with ribonucleotide at~~ -~~3 position~~	+	[[Category: DNA-directed DNA polymerase]]
		+	[[Category: Enterobacteria phage rb69]]
		+	[[Category: Clausen, A R.]]
		+	[[Category: Pedersen, L C.]]
		+	[[Category: Ribonucleotide]]
		+	[[Category: Transferase-dna complex]]

OCA at 11:39, 19 June 2013

OCA — Wed, 19 Jun 2013 11:39:26 GMT

←Older revision		Revision as of 11:39, 19 June 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4khy is ON HOLD	+	The entry 4khy is ON HOLD until Paper Publication

	Authors: Clausen, A.R., Pedersen, L.C.		Authors: Clausen, A.R., Pedersen, L.C.

	Description: Ternary complex of rb69 mutant L415F with ribonucleotide at -3 position		Description: Ternary complex of rb69 mutant L415F with ribonucleotide at -3 position

OCA: Protected "4khy" [edit=sysop:move=sysop]

OCA — Wed, 08 May 2013 07:24:17 GMT

Protected "4khy" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:24, 8 May 2013

OCA: New page: '''Unreleased structure''' The entry 4khy is ON HOLD Authors: Clausen, A.R., Pedersen, L.C. Description: Ternary complex of rb69 mutant L415F with ribonucleotide at -3 position

OCA — Wed, 08 May 2013 07:24:16 GMT

New page: '''Unreleased structure''' The entry 4khy is ON HOLD Authors: Clausen, A.R., Pedersen, L.C. Description: Ternary complex of rb69 mutant L415F with ribonucleotide at -3 position

New page

'''Unreleased structure'''

The entry 4khy is ON HOLD

Authors: Clausen, A.R., Pedersen, L.C.

Description: Ternary complex of rb69 mutant L415F with ribonucleotide at -3 position