4kku - Revision history

OCA at 08:56, 7 December 2022

OCA — Wed, 07 Dec 2022 08:56:45 GMT

←Older revision		Revision as of 08:56, 7 December 2022
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	==Structure of BesA (Selenomethinone derivative - P212121)==		==Structure of BesA (Selenomethinone derivative - P212121)==
-	<StructureSection load='4kku' size='340' side='right' caption='[[4kku]], [[Resolution\|resolution]] 2.35Å' scene=''>	+	<StructureSection load='4kku' size='340' side='right'caption='[[4kku]], [[Resolution\|resolution]] 2.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4kku]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Borbu Borbu~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KKU OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4KKU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4kku]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Borreliella_burgdorferi_B31 Borreliella burgdorferi B31]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KKU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KKU FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4kks\|4kks]], [[4kkt\|4kkt]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kku FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kku OCA], [https://pdbe.org/4kku PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kku RCSB], [https://www.ebi.ac.uk/pdbsum/4kku PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kku ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BB_0141 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224326 BORBU])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4kku FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kku OCA], [~~http~~://pdbe.org/4kku PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4kku RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4kku PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4kku ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/O51166_BORBU O51166_BORBU]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Borbu~~]]	+	[[Category: Borreliella burgdorferi B31]]
-	[[Category: Ababou, A]]	+	[[Category: Large Structures]]
-	[[Category: Crow, A]]	+	[[Category: Ababou A]]
-	[[Category: Greene~~, N P~~]]	+	[[Category: Crow A]]
-	[[Category: Hinchliffe, P]]	+	[[Category: Greene NP]]
-	[[Category: Hughes, C]]	+	[[Category: Hinchliffe P]]
-	[[Category: Koronakis, V]]	+	[[Category: Hughes C]]
-	~~[[Category: Membrane protein~~]]	+	[[Category: Koronakis V]]

OCA at 10:42, 11 August 2016

OCA — Thu, 11 Aug 2016 10:42:34 GMT

←Older revision		Revision as of 10:42, 11 August 2016
Line 1:		Line 1:
		+
	==Structure of BesA (Selenomethinone derivative - P212121)==		==Structure of BesA (Selenomethinone derivative - P212121)==
	<StructureSection load='4kku' size='340' side='right' caption='[[4kku]], [[Resolution\|resolution]] 2.35Å' scene=''>		<StructureSection load='4kku' size='340' side='right' caption='[[4kku]], [[Resolution\|resolution]] 2.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4kku]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Borrelia_burgdorferi_b31 Borrelia burgdorferi b31~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KKU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KKU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4kku]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Borbu Borbu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KKU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KKU FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4kks\|4kks]], [[4kkt\|4kkt]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4kks\|4kks]], [[4kkt\|4kkt]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BB_0141 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224326 ~~Borrelia burgdorferi B31~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BB_0141 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224326 BORBU])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kku FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kku OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kku RCSB], [http://www.ebi.ac.uk/pdbsum/4kku PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kku FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kku OCA], [http://pdbe.org/4kku PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4kku RCSB], [http://www.ebi.ac.uk/pdbsum/4kku PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4kku ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4kku" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Borrelia burgdorferi b31~~]]	+	[[Category: Borbu]]
	[[Category: Ababou, A]]		[[Category: Ababou, A]]
	[[Category: Crow, A]]		[[Category: Crow, A]]

OCA at 12:22, 5 January 2015

OCA — Mon, 05 Jan 2015 12:22:44 GMT

←Older revision		Revision as of 12:22, 5 January 2015
Line 1:		Line 1:
-	~~{{STRUCTURE_4kku\| PDB=4kku \| SCENE= }}~~	+	==Structure of BesA (Selenomethinone derivative - P212121)==
-	===Structure of BesA (Selenomethinone derivative - P212121)===	+	<StructureSection load='4kku' size='340' side='right' caption='[[4kku]], [[Resolution\|resolution]] 2.35Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23851070}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4kku]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Borrelia_burgdorferi_b31 Borrelia burgdorferi b31]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KKU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KKU FirstGlance]. <br>
		+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4kks\|4kks]], [[4kkt\|4kkt]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BB_0141 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224326 Borrelia burgdorferi B31])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kku FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kku OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kku RCSB], [http://www.ebi.ac.uk/pdbsum/4kku PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Periplasmic adaptor proteins are essential components of bacterial tripartite multidrug efflux pumps. Here we report the 2.35A resolution crystal structure of the BesA adaptor from the spirochete Borrelia burgdorferi solved using selenomethionine derivatized protein. BesA shows the archetypal linear, flexible, multi-domain architecture evident among proteobacteria and retains the lipoyl, beta-barrel and membrane-proximal domains that interact with the periplasmic domains of the inner membrane transporter. However, it lacks the alpha-hairpin domain shown to establish extensive coiled-coil interactions with the periplasmic entrance helices of the outer membrane-anchored TolC exit duct. This has implications for the modelling of assembled tripartite efflux pumps.

-	~~==About this~~ Structure==	+	Structure of an atypical periplasmic adaptor from a multidrug efflux pump of the spirochete Borrelia burgdorferi.,Greene NP, Hinchliffe P, Crow A, Ababou A, Hughes C, Koronakis V FEBS Lett. 2013 Jul 9. pii: S0014-5793(13)00520-6. doi:, 10.1016/j.febslet.2013.06.056. PMID:23851070<ref>PMID:23851070</ref>
-	~~[[4kku]] is~~ a ~~4 chain structure with sequence from [http://en.wikipedia.org/wiki/Borrelia_burgdorferi_b31~~ Borrelia burgdorferi ~~b31]~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=4KKU OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:023851070</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Borrelia burgdorferi b31]]		[[Category: Borrelia burgdorferi b31]]
-	[[Category: Ababou, A.]]	+	[[Category: Ababou, A]]
-	[[Category: Crow, A.]]	+	[[Category: Crow, A]]
-	[[Category: Greene, N P.]]	+	[[Category: Greene, N P]]
-	[[Category: Hinchliffe, P.]]	+	[[Category: Hinchliffe, P]]
-	[[Category: Hughes, C.]]	+	[[Category: Hughes, C]]
-	[[Category: Koronakis, V.]]	+	[[Category: Koronakis, V]]
	[[Category: Membrane protein]]		[[Category: Membrane protein]]

OCA at 03:26, 1 August 2013

OCA — Thu, 01 Aug 2013 03:26:17 GMT

←Older revision		Revision as of 03:26, 1 August 2013
Line 1:		Line 1:
	{{STRUCTURE_4kku\| PDB=4kku \| SCENE= }}		{{STRUCTURE_4kku\| PDB=4kku \| SCENE= }}
	===Structure of BesA (Selenomethinone derivative - P212121)===		===Structure of BesA (Selenomethinone derivative - P212121)===
		+	{{ABSTRACT_PUBMED_23851070}}

	==About this Structure==		==About this Structure==
	[[4kku]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Borrelia_burgdorferi_b31 Borrelia burgdorferi b31]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KKU OCA].		[[4kku]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Borrelia_burgdorferi_b31 Borrelia burgdorferi b31]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KKU OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:023851070</ref><references group="xtra"/><references/>
	[[Category: Borrelia burgdorferi b31]]		[[Category: Borrelia burgdorferi b31]]
	[[Category: Ababou, A.]]		[[Category: Ababou, A.]]

OCA at 04:01, 18 July 2013

OCA — Thu, 18 Jul 2013 04:01:39 GMT

←Older revision		Revision as of 04:01, 18 July 2013
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	[[Category: Ababou, A.]]		[[Category: Ababou, A.]]
	[[Category: Crow, A.]]		[[Category: Crow, A.]]
-	[[Category: ~~Green~~, N P.]]	+	[[Category: Greene, N P.]]
	[[Category: Hinchliffe, P.]]		[[Category: Hinchliffe, P.]]
	[[Category: Hughes, C.]]		[[Category: Hughes, C.]]
	[[Category: Koronakis, V.]]		[[Category: Koronakis, V.]]
	[[Category: Membrane protein]]		[[Category: Membrane protein]]

OCA at 15:55, 10 July 2013

OCA — Wed, 10 Jul 2013 15:55:04 GMT

←Older revision		Revision as of 15:55, 10 July 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4kku\| PDB=4kku \| SCENE= }}
		+	===Structure of BesA (Selenomethinone derivative - P212121)===

-	~~The entry~~ 4kku is ~~ON HOLD~~	+	==About this Structure==
-		+	[[4kku]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Borrelia_burgdorferi_b31 Borrelia burgdorferi b31]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KKU OCA].
-	~~Authors~~: ~~Green, N~~.P.~~, Hinchliffe, P~~., Crow, A., ~~Ababou, A~~., Hughes, C., Koronakis, V.	+	[[Category: Borrelia burgdorferi b31]]
-		+	[[Category: Ababou, A.]]
-	~~Description~~: ~~Structure of BesA (Selenomethinone derivative -P212121)~~	+	[[Category: Crow, A.]]
		+	[[Category: Green, N P.]]
		+	[[Category: Hinchliffe, P.]]
		+	[[Category: Hughes, C.]]
		+	[[Category: Koronakis, V.]]
		+	[[Category: Membrane protein]]

OCA at 11:42, 19 June 2013

OCA — Wed, 19 Jun 2013 11:42:13 GMT

←Older revision		Revision as of 11:42, 19 June 2013
Line 3:		Line 3:
	The entry 4kku is ON HOLD		The entry 4kku is ON HOLD

-	Authors: Green, N.P., ~~HInchliffe~~, P., Crow, A., Ababou, A., Hughes, C., Koronakis, V.	+	Authors: Green, N.P., Hinchliffe, P., Crow, A., Ababou, A., Hughes, C., Koronakis, V.

	Description: Structure of BesA (Selenomethinone derivative -P212121)		Description: Structure of BesA (Selenomethinone derivative -P212121)

OCA: Protected "4kku" [edit=sysop:move=sysop]

OCA — Thu, 16 May 2013 06:58:15 GMT

Protected "4kku" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:58, 16 May 2013

OCA: New page: '''Unreleased structure''' The entry 4kku is ON HOLD Authors: Green, N.P., HInchliffe, P., Crow, A., Ababou, A., Hughes, C., Koronakis, V. Description: Structure of BesA (Selenomethino...

OCA — Thu, 16 May 2013 06:58:14 GMT

New page: '''Unreleased structure''' The entry 4kku is ON HOLD Authors: Green, N.P., HInchliffe, P., Crow, A., Ababou, A., Hughes, C., Koronakis, V. Description: Structure of BesA (Selenomethino...

New page

'''Unreleased structure'''

The entry 4kku is ON HOLD

Authors: Green, N.P., HInchliffe, P., Crow, A., Ababou, A., Hughes, C., Koronakis, V.

Description: Structure of BesA (Selenomethinone derivative -P212121)