4kpd - Revision history

OCA at 16:03, 20 September 2023

OCA — Wed, 20 Sep 2023 16:03:18 GMT

←Older revision		Revision as of 16:03, 20 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4kpd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KPD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KPD FirstGlance]. <br>		<table><tr><td colspan='2'>[[4kpd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KPD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KPD FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPE:3-METHYLBUT-3-ENYL+TRIHYDROGEN+DIPHOSPHATE'>IPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RIS:1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE+BIS-PHOSPHONIC+ACID'>RIS</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.96Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPE:3-METHYLBUT-3-ENYL+TRIHYDROGEN+DIPHOSPHATE'>IPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RIS:1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE+BIS-PHOSPHONIC+ACID'>RIS</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kpd OCA], [https://pdbe.org/4kpd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kpd RCSB], [https://www.ebi.ac.uk/pdbsum/4kpd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kpd ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kpd OCA], [https://pdbe.org/4kpd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kpd RCSB], [https://www.ebi.ac.uk/pdbsum/4kpd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kpd ProSAT]</span></td></tr>
	</table>		</table>

OCA at 09:04, 7 December 2022

OCA — Wed, 07 Dec 2022 09:04:57 GMT

←Older revision		Revision as of 09:04, 7 December 2022
Line 1:		Line 1:

	==Crystal Structure of Human Farnesyl Pyrophosphate Synthase (Y204F) Mutant Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate==		==Crystal Structure of Human Farnesyl Pyrophosphate Synthase (Y204F) Mutant Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate==
-	<StructureSection load='4kpd' size='340' side='right' caption='[[4kpd]], [[Resolution\|resolution]] 1.96Å' scene=''>	+	<StructureSection load='4kpd' size='340' side='right'caption='[[4kpd]], [[Resolution\|resolution]] 1.96Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4kpd]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KPD OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4KPD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4kpd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KPD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KPD FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IPE:3-METHYLBUT-3-ENYL+TRIHYDROGEN+DIPHOSPHATE'>IPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RIS:1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE+BIS-PHOSPHONIC+ACID'>RIS</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPE:3-METHYLBUT-3-ENYL+TRIHYDROGEN+DIPHOSPHATE'>IPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RIS:1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE+BIS-PHOSPHONIC+ACID'>RIS</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4kfa\|4kfa]], [[4kpj\|4kpj]], [[4kq5\|4kq5]], [[4kqs\|4kqs]], [[4kqu\|4kqu]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kpd OCA], [https://pdbe.org/4kpd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kpd RCSB], [https://www.ebi.ac.uk/pdbsum/4kpd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kpd ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FDPS, FPS, KIAA1293 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4kpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kpd OCA], [~~http~~://pdbe.org/4kpd PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4kpd RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4kpd PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4kpd ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/FPPS_HUMAN FPPS_HUMAN]] Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.	+	[https://www.uniprot.org/uniprot/FPPS_HUMAN FPPS_HUMAN] Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.

	==See Also==		==See Also==
-	*[[Farnesyl diphosphate synthase\|Farnesyl diphosphate synthase]]	+	*[[Farnesyl diphosphate synthase 3D structures\|Farnesyl diphosphate synthase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: ~~Barnett, B L~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Muniz, J R.C~~]]	+	[[Category: Barnett BL]]
-	[[Category: ~~Tsoumpra, M K~~]]	+	[[Category: Muniz JRC]]
-	[[Category: ~~Walter, R L~~]]	+	[[Category: Tsoumpra MK]]
-	[[Category: ~~Bisphosphonate]]~~	+	[[Category: Walter RL]]
-	~~[[Category: Cholesterol synthesis]]~~	+
-	~~[[Category: Dimethylallyl pyrophosphate]]~~	+
-	~~[[Category: Isoprene biosynthesis]]~~	+
-	~~[[Category: Isoprenoid pathway]]~~	+
-	~~[[Category: Lipid synthesis]]~~	+
-	~~[[Category: Steroid biosynthesis]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 11:58, 4 August 2016

OCA — Thu, 04 Aug 2016 11:58:08 GMT

←Older revision		Revision as of 11:58, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal Structure of Human Farnesyl Pyrophosphate Synthase (Y204F) Mutant Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate==		==Crystal Structure of Human Farnesyl Pyrophosphate Synthase (Y204F) Mutant Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate==
	<StructureSection load='4kpd' size='340' side='right' caption='[[4kpd]], [[Resolution\|resolution]] 1.96Å' scene=''>		<StructureSection load='4kpd' size='340' side='right' caption='[[4kpd]], [[Resolution\|resolution]] 1.96Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4kfa\|4kfa]], [[4kpj\|4kpj]], [[4kq5\|4kq5]], [[4kqs\|4kqs]], [[4kqu\|4kqu]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4kfa\|4kfa]], [[4kpj\|4kpj]], [[4kq5\|4kq5]], [[4kqs\|4kqs]], [[4kqu\|4kqu]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FDPS, FPS, KIAA1293 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FDPS, FPS, KIAA1293 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kpd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kpd RCSB], [http://www.ebi.ac.uk/pdbsum/4kpd PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kpd OCA], [http://pdbe.org/4kpd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4kpd RCSB], [http://www.ebi.ac.uk/pdbsum/4kpd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4kpd ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/FPPS_HUMAN FPPS_HUMAN]] Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.		[[http://www.uniprot.org/uniprot/FPPS_HUMAN FPPS_HUMAN]] Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
		+
		+	==See Also==
		+	*[[Farnesyl diphosphate synthase\|Farnesyl diphosphate synthase]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 09:05, 25 December 2014

OCA — Thu, 25 Dec 2014 09:05:55 GMT

←Older revision		Revision as of 09:05, 25 December 2014
Line 2:		Line 2:
	<StructureSection load='4kpd' size='340' side='right' caption='[[4kpd]], [[Resolution\|resolution]] 1.96Å' scene=''>		<StructureSection load='4kpd' size='340' side='right' caption='[[4kpd]], [[Resolution\|resolution]] 1.96Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4kpd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KPD OCA]. <br>	+	<table><tr><td colspan='2'>[[4kpd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KPD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KPD FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IPE:3-METHYLBUT-3-ENYL+TRIHYDROGEN+DIPHOSPHATE'>IPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RIS:1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE+BIS-PHOSPHONIC+ACID'>RIS</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IPE:3-METHYLBUT-3-ENYL+TRIHYDROGEN+DIPHOSPHATE'>IPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RIS:1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE+BIS-PHOSPHONIC+ACID'>RIS</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4kfa\|4kfa]], [[4kpj\|4kpj]], [[4kq5\|4kq5]], [[4kqs\|4kqs]], [[4kqu\|4kqu]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4kfa\|4kfa]], [[4kpj\|4kpj]], [[4kq5\|4kq5]], [[4kqs\|4kqs]], [[4kqu\|4kqu]]</td></tr>
-	<tr><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat">~~<span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase]~~, ~~with EC number~~ [http://www.~~brenda-enzymes~~.~~info~~/~~php~~/~~result_flat~~.~~php4~~?~~ecno~~=~~2.7.1.2 2.7.1.2~~] ~~</span>~~</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FDPS, FPS, KIAA1293 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kpd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kpd RCSB], [http://www.ebi.ac.uk/pdbsum/4kpd PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kpd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kpd RCSB], [http://www.ebi.ac.uk/pdbsum/4kpd PDBsum]</span></td></tr>
-	<table>	+	</table>
-	== ~~References~~ ==	+	== Function ==
-	~~<references~~/>	+	[[http://www.uniprot.org/uniprot/FPPS_HUMAN FPPS_HUMAN]] Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Barnett, B L.]]	+	[[Category: Human]]
-	[[Category: Muniz, J R.C.]]	+	[[Category: Barnett, B L]]
-	[[Category: Tsoumpra, M K.]]	+	[[Category: Muniz, J R.C]]
-	[[Category: Walter, R L.]]	+	[[Category: Tsoumpra, M K]]
		+	[[Category: Walter, R L]]
	[[Category: Bisphosphonate]]		[[Category: Bisphosphonate]]
	[[Category: Cholesterol synthesis]]		[[Category: Cholesterol synthesis]]

OCA at 09:26, 1 May 2014

OCA — Thu, 01 May 2014 09:26:22 GMT

←Older revision		Revision as of 09:26, 1 May 2014
Line 2:		Line 2:
	<StructureSection load='4kpd' size='340' side='right' caption='[[4kpd]], [[Resolution\|resolution]] 1.96Å' scene=''>		<StructureSection load='4kpd' size='340' side='right' caption='[[4kpd]], [[Resolution\|resolution]] 1.96Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	[[4kpd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KPD OCA]. <br>	+	<table><tr><td colspan='2'>[[4kpd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KPD OCA]. <br>
-	<b>[[Ligand\|Ligands:]]</b> <scene name='pdbligand=IPE:3-METHYLBUT-3-ENYL+TRIHYDROGEN+DIPHOSPHATE'>IPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RIS:1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE+BIS-PHOSPHONIC+ACID'>RIS</scene><br>	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IPE:3-METHYLBUT-3-ENYL+TRIHYDROGEN+DIPHOSPHATE'>IPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RIS:1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE+BIS-PHOSPHONIC+ACID'>RIS</scene><br>
-	<b>[[Related_structure\|Related:]]</b> [[4kfa\|4kfa]], [[4kpj\|4kpj]], [[4kq5\|4kq5]], [[4kqs\|4kqs]], [[4kqu\|4kqu]]<br>	+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4kfa\|4kfa]], [[4kpj\|4kpj]], [[4kq5\|4kq5]], [[4kqs\|4kqs]], [[4kqu\|4kqu]]</td></tr>
-	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>	+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
-	<b>Resources:</b> <span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kpd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kpd RCSB], [http://www.ebi.ac.uk/pdbsum/4kpd PDBsum]</span><br>	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kpd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kpd RCSB], [http://www.ebi.ac.uk/pdbsum/4kpd PDBsum]</span></td></tr>
		+	<table>
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:56, 30 April 2014

OCA — Wed, 30 Apr 2014 09:56:39 GMT

←Older revision		Revision as of 09:56, 30 April 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	[[4kpd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KPD OCA]. <br>		[[4kpd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KPD OCA]. <br>
-	<b>Related:</b> [[4kfa\|4kfa]], [[4kpj\|4kpj]], [[4kq5\|4kq5]], [[4kqs\|4kqs]], [[4kqu\|4kqu]]<br>	+	<b>[[Ligand\|Ligands:]]</b> <scene name='pdbligand=IPE:3-METHYLBUT-3-ENYL+TRIHYDROGEN+DIPHOSPHATE'>IPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RIS:1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE+BIS-PHOSPHONIC+ACID'>RIS</scene><br>
		+	<b>[[Related_structure\|Related:]]</b> [[4kfa\|4kfa]], [[4kpj\|4kpj]], [[4kq5\|4kq5]], [[4kqs\|4kqs]], [[4kqu\|4kqu]]<br>
	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>		<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
		+	<b>Resources:</b> <span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kpd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kpd RCSB], [http://www.ebi.ac.uk/pdbsum/4kpd PDBsum]</span><br>
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:00, 30 April 2014

OCA — Wed, 30 Apr 2014 08:00:31 GMT

←Older revision		Revision as of 08:00, 30 April 2014
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Crystal Structure of Human Farnesyl Pyrophosphate Synthase (Y204F) Mutant Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate==
-		+	<StructureSection load='4kpd' size='340' side='right' caption='[[4kpd]], [[Resolution\|resolution]] 1.96Å' scene=''>
-	~~The entry~~ 4kpd is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	[[4kpd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KPD OCA]. <br>
-	~~Authors~~: ~~Barnett~~, B.L., ~~Tsoumpra, M~~.K., Muniz, J.R.C., Walter, R.L.	+	<b>Related:</b> [[4kfa\|4kfa]], [[4kpj\|4kpj]], [[4kq5\|4kq5]], [[4kqs\|4kqs]], [[4kqu\|4kqu]]<br>
-		+	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
-	~~Description~~: ~~Crystal Structure of Human Farnesyl Pyrophosphate Synthase (Y204F) Mutant Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate~~	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Barnett, B L.]]
		+	[[Category: Muniz, J R.C.]]
		+	[[Category: Tsoumpra, M K.]]
		+	[[Category: Walter, R L.]]
		+	[[Category: Bisphosphonate]]
		+	[[Category: Cholesterol synthesis]]
		+	[[Category: Dimethylallyl pyrophosphate]]
		+	[[Category: Isoprene biosynthesis]]
		+	[[Category: Isoprenoid pathway]]
		+	[[Category: Lipid synthesis]]
		+	[[Category: Steroid biosynthesis]]
		+	[[Category: Transferase]]

OCA at 07:31, 15 January 2014

OCA — Wed, 15 Jan 2014 07:31:44 GMT

←Older revision		Revision as of 07:31, 15 January 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4kpd is ON HOLD	+	The entry 4kpd is ON HOLD until Paper Publication

	Authors: Barnett, B.L., Tsoumpra, M.K., Muniz, J.R.C., Walter, R.L.		Authors: Barnett, B.L., Tsoumpra, M.K., Muniz, J.R.C., Walter, R.L.

	Description: Crystal Structure of Human Farnesyl Pyrophosphate Synthase (Y204F) Mutant Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate		Description: Crystal Structure of Human Farnesyl Pyrophosphate Synthase (Y204F) Mutant Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate

OCA: Protected "4kpd" [edit=sysop:move=sysop]

OCA — Wed, 19 Jun 2013 11:51:53 GMT

Protected "4kpd" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:51, 19 June 2013

OCA: New page: '''Unreleased structure''' The entry 4kpd is ON HOLD Authors: Barnett, B.L., Tsoumpra, M.K., Muniz, J.R.C., Walter, R.L. Description: Crystal Structure of Human Farnesyl Pyrophosphate ...

OCA — Wed, 19 Jun 2013 11:51:52 GMT

New page: '''Unreleased structure''' The entry 4kpd is ON HOLD Authors: Barnett, B.L., Tsoumpra, M.K., Muniz, J.R.C., Walter, R.L. Description: Crystal Structure of Human Farnesyl Pyrophosphate ...

New page

'''Unreleased structure'''

The entry 4kpd is ON HOLD

Authors: Barnett, B.L., Tsoumpra, M.K., Muniz, J.R.C., Walter, R.L.

Description: Crystal Structure of Human Farnesyl Pyrophosphate Synthase (Y204F) Mutant Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate