4l5f - Revision history

OCA at 09:33, 7 December 2022

OCA — Wed, 07 Dec 2022 09:33:24 GMT

←Older revision		Revision as of 09:33, 7 December 2022
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	==Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII==		==Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII==
-	<StructureSection load='4l5f' size='340' side='right' caption='[[4l5f]], [[Resolution\|resolution]] 2.45Å' scene=''>	+	<StructureSection load='4l5f' size='340' side='right'caption='[[4l5f]], [[Resolution\|resolution]] 2.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4l5f]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Dengue_virus_1 Dengue virus 1] and [~~http~~://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L5F OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4L5F FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4l5f]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_1 Dengue virus 1] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L5F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L5F FirstGlance]. <br>
-	</td></tr>~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11053 Dengue virus 1])</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l5f OCA], [https://pdbe.org/4l5f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l5f RCSB], [https://www.ebi.ac.uk/pdbsum/4l5f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l5f ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4l5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l5f OCA], [~~http~~://pdbe.org/4l5f PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4l5f RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4l5f PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4l5f ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/Q8BE40_9FLAV Q8BE40_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]	+	[https://www.uniprot.org/uniprot/Q8BE40_9FLAV Q8BE40_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]

	==See Also==		==See Also==
-	*[[3D structures of ~~monoclonal~~ antibody\|3D structures of ~~monoclonal~~ antibody]]	+	*[[Antibody 3D structures\|Antibody 3D structures]]
		+	*[[Monoclonal Antibodies 3D structures\|Monoclonal Antibodies 3D structures]]
		+	*[[3D structures of non-human antibody\|3D structures of non-human antibody]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Dengue virus 1]]		[[Category: Dengue virus 1]]
		+	[[Category: Large Structures]]
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	~~[[Category: Structural genomic]]~~	+	[[Category: Edeling MA]]
-	[[Category: Edeling~~, M A~~]]	+	[[Category: Fremont DH]]
-	[[Category: Fremont~~, D H~~]]	+	[[Category: Nelson CA]]
-	[[Category: Nelson~~, C A]]~~	+
-	~~[[Category: Antibody]]~~	+
-	~~[[Category: Antibody epitope]]~~	+
-	~~[[Category: Envelope]]~~	+
-	~~[[Category: Fab]]~~	+
-	~~[[Category: Immune system]]~~	+
-	~~[[Category: Infectious disease]]~~	+
-	~~[[Category: National institute of allergy and infectious disease]]~~	+
-	~~[[Category: Neutralizing]]~~	+
-	~~[[Category: Niaid]]~~	+
-	~~[[Category: Viral protein]]~~	+
-	~~[[Category: Virus~~]]	+

OCA at 13:45, 4 August 2016

OCA — Thu, 04 Aug 2016 13:45:34 GMT

←Older revision		Revision as of 13:45, 4 August 2016
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		+
	==Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII==		==Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII==
	<StructureSection load='4l5f' size='340' side='right' caption='[[4l5f]], [[Resolution\|resolution]] 2.45Å' scene=''>		<StructureSection load='4l5f' size='340' side='right' caption='[[4l5f]], [[Resolution\|resolution]] 2.45Å' scene=''>
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	<table><tr><td colspan='2'>[[4l5f]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_1 Dengue virus 1] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L5F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4L5F FirstGlance]. <br>		<table><tr><td colspan='2'>[[4l5f]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_1 Dengue virus 1] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L5F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4L5F FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11053 Dengue virus 1])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11053 Dengue virus 1])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l5f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l5f RCSB], [http://www.ebi.ac.uk/pdbsum/4l5f PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l5f OCA], [http://pdbe.org/4l5f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4l5f RCSB], [http://www.ebi.ac.uk/pdbsum/4l5f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4l5f ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 10:		Line 11:

	==See Also==		==See Also==
-	*[[~~Monoclonal Antibody~~\|~~Monoclonal Antibody~~]]	+	*[[3D structures of monoclonal antibody\|3D structures of monoclonal antibody]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 09:51, 25 December 2014

OCA — Thu, 25 Dec 2014 09:51:18 GMT

←Older revision		Revision as of 09:51, 25 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l5f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l5f RCSB], [http://www.ebi.ac.uk/pdbsum/4l5f PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l5f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l5f RCSB], [http://www.ebi.ac.uk/pdbsum/4l5f PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/Q8BE40_9FLAV Q8BE40_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]

	==See Also==		==See Also==

OCA at 18:12, 21 December 2014

OCA — Sun, 21 Dec 2014 18:12:07 GMT

←Older revision		Revision as of 18:12, 21 December 2014
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-	~~{{STRUCTURE_4l5f\| PDB=4l5f \| SCENE= }}~~	+	==Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII==
-	===Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII===	+	<StructureSection load='4l5f' size='340' side='right' caption='[[4l5f]], [[Resolution\|resolution]] 2.45Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4l5f]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_1 Dengue virus 1] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L5F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4L5F FirstGlance]. <br>
		+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11053 Dengue virus 1])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l5f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l5f RCSB], [http://www.ebi.ac.uk/pdbsum/4l5f PDBsum]</span></td></tr>
		+	</table>

-	==~~Function~~==	+	==See Also==
-	[[~~http://www.uniprot.org/uniprot/Q8BE40_9FLAV Q8BE40_9FLAV~~]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]	+	*[[Monoclonal Antibody\|Monoclonal Antibody]]
-		+	__TOC__
-	~~==About this Structure==~~	+	</StructureSection>
-	[[~~4l5f]] is a 3 chain structure with sequence from [http~~:~~//en.wikipedia.org/wiki/~~ ] ~~and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L5F OCA~~].	+	[[Category: Dengue virus 1]]
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: ~~CSGID, Center for~~ Structural ~~Genomics of Infectious Diseases.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Edeling, M A.]]	+	[[Category: Edeling, M A]]
-	[[Category: Fremont, D H.]]	+	[[Category: Fremont, D H]]
-	[[Category: Nelson, C A.]]	+	[[Category: Nelson, C A]]
	[[Category: Antibody]]		[[Category: Antibody]]
	[[Category: Antibody epitope]]		[[Category: Antibody epitope]]

OCA at 13:49, 11 December 2013

OCA — Wed, 11 Dec 2013 13:49:21 GMT

←Older revision		Revision as of 13:49, 11 December 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4l5f\| PDB=4l5f \| SCENE= }}
		+	===Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII===

-	~~The entry 4l5f~~ is ~~ON HOLD~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/Q8BE40_9FLAV Q8BE40_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]

-	~~Authors~~: ~~Edeling, M~~.A.~~, Nelson, C~~.A.~~, Fremont, D~~.H., Center for Structural Genomics of Infectious Diseases ~~(CSGID)~~	+	==About this Structure==
-		+	[[4l5f]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L5F OCA].
-	~~Description~~: ~~Crystal Structure of DENV1-E106 Fab bound to DENV-1~~ Envelope protein ~~DIII~~	+	[[Category: Mus musculus]]
		+	[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
		+	[[Category: Edeling, M A.]]
		+	[[Category: Fremont, D H.]]
		+	[[Category: Nelson, C A.]]
		+	[[Category: Antibody]]
		+	[[Category: Antibody epitope]]
		+	[[Category: Envelope]]
		+	[[Category: Fab]]
		+	[[Category: Immune system]]
		+	[[Category: Infectious disease]]
		+	[[Category: National institute of allergy and infectious disease]]
		+	[[Category: Neutralizing]]
		+	[[Category: Niaid]]
		+	[[Category: Viral protein]]
		+	[[Category: Virus]]

OCA: Protected "4l5f" [edit=sysop:move=sysop]

OCA — Wed, 19 Jun 2013 12:33:22 GMT

Protected "4l5f" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:33, 19 June 2013

OCA: New page: '''Unreleased structure''' The entry 4l5f is ON HOLD Authors: Edeling, M.A., Nelson, C.A., Fremont, D.H., Center for Structural Genomics of Infectious Diseases (CSGID) Description: Cry...

OCA — Wed, 19 Jun 2013 12:33:19 GMT

New page: '''Unreleased structure''' The entry 4l5f is ON HOLD Authors: Edeling, M.A., Nelson, C.A., Fremont, D.H., Center for Structural Genomics of Infectious Diseases (CSGID) Description: Cry...

New page

'''Unreleased structure'''

The entry 4l5f is ON HOLD

Authors: Edeling, M.A., Nelson, C.A., Fremont, D.H., Center for Structural Genomics of Infectious Diseases (CSGID)

Description: Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII