4lwl - Revision history

OCA at 14:38, 8 November 2023

OCA — Wed, 08 Nov 2023 14:38:57 GMT

←Older revision		Revision as of 14:38, 8 November 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4lwl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkaliphilus_oremlandii_OhILAs Alkaliphilus oremlandii OhILAs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LWL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LWL FirstGlance]. <br>		<table><tr><td colspan='2'>[[4lwl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkaliphilus_oremlandii_OhILAs Alkaliphilus oremlandii OhILAs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LWL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LWL FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lwl OCA], [https://pdbe.org/4lwl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lwl RCSB], [https://www.ebi.ac.uk/pdbsum/4lwl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lwl ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lwl OCA], [https://pdbe.org/4lwl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lwl RCSB], [https://www.ebi.ac.uk/pdbsum/4lwl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lwl ProSAT]</span></td></tr>
	</table>		</table>

OCA at 10:37, 21 December 2022

OCA — Wed, 21 Dec 2022 10:37:58 GMT

←Older revision		Revision as of 10:37, 21 December 2022
Line 3:		Line 3:
	<StructureSection load='4lwl' size='340' side='right'caption='[[4lwl]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='4lwl' size='340' side='right'caption='[[4lwl]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4lwl]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Alkoo Alkoo~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LWL OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4LWL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4lwl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkaliphilus_oremlandii_OhILAs Alkaliphilus oremlandii OhILAs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LWL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LWL FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene~~></td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lwl OCA], [https://pdbe.org/4lwl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lwl RCSB], [https://www.ebi.ac.uk/pdbsum/4lwl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lwl ProSAT]</span></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4lwj\|4lwj]], [[4lwk\|4lwk]], [[4lwm\|4lwm]], [[4lwn\|4lwn]]</td></tr>~~	+
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">msrA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=350688 ALKOO])</td></tr>~~	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide-methionine_(S)-S-oxide_reductase Peptide-methionine (S)-S-oxide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.4.11 1.8.4.11] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4lwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lwl OCA], [~~http~~://pdbe.org/4lwl PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4lwl RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4lwl PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4lwl ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/A8MI53_ALKOO A8MI53_ALKOO]] Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).[HAMAP-Rule:MF_01401]	+	[https://www.uniprot.org/uniprot/A8MI53_ALKOO A8MI53_ALKOO] Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).[HAMAP-Rule:MF_01401]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Alkoo~~]]	+	[[Category: Alkaliphilus oremlandii OhILAs]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Hwang~~, K Y~~]]	+	[[Category: Hwang KY]]
-	[[Category: Lee~~, E H]]~~	+	[[Category: Lee EH]]
-	~~[[Category: Alpha/beta fold]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 06:07, 7 August 2019

OCA — Wed, 07 Aug 2019 06:07:58 GMT

←Older revision		Revision as of 06:07, 7 August 2019
Line 1:		Line 1:

	==Crystal structure of methionine sulfoxide reductase U16C/E55A from clostridium oremlandii==		==Crystal structure of methionine sulfoxide reductase U16C/E55A from clostridium oremlandii==
-	<StructureSection load='4lwl' size='340' side='right' caption='[[4lwl]], [[Resolution\|resolution]] 1.60Å' scene=''>	+	<StructureSection load='4lwl' size='340' side='right'caption='[[4lwl]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4lwl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Alkoo Alkoo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LWL FirstGlance]. <br>		<table><tr><td colspan='2'>[[4lwl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Alkoo Alkoo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LWL FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
-	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=CSE:SELENOCYSTEINE'>CSE</scene>,~~ <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4lwj\|4lwj]], [[4lwk\|4lwk]], [[4lwm\|4lwm]], [[4lwn\|4lwn]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4lwj\|4lwj]], [[4lwk\|4lwk]], [[4lwm\|4lwm]], [[4lwn\|4lwn]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">msrA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=350688 ALKOO])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">msrA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=350688 ALKOO])</td></tr>
Line 27:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Alkoo]]		[[Category: Alkoo]]
		+	[[Category: Large Structures]]
	[[Category: Hwang, K Y]]		[[Category: Hwang, K Y]]
	[[Category: Lee, E H]]		[[Category: Lee, E H]]
	[[Category: Alpha/beta fold]]		[[Category: Alpha/beta fold]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 09:44, 15 November 2017

OCA — Wed, 15 Nov 2017 09:44:16 GMT

←Older revision		Revision as of 09:44, 15 November 2017
Line 3:		Line 3:
	<StructureSection load='4lwl' size='340' side='right' caption='[[4lwl]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='4lwl' size='340' side='right' caption='[[4lwl]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4lwl]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LWL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4lwl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Alkoo Alkoo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LWL FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
-	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSE:SELENOCYSTEINE'>CSE</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4lwj\|4lwj]], [[4lwk\|4lwk]], [[4lwm\|4lwm]], [[4lwn\|4lwn]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4lwj\|4lwj]], [[4lwk\|4lwk]], [[4lwm\|4lwm]], [[4lwn\|4lwn]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">msrA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=350688 ALKOO])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide-methionine_(S)-S-oxide_reductase Peptide-methionine (S)-S-oxide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.4.11 1.8.4.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide-methionine_(S)-S-oxide_reductase Peptide-methionine (S)-S-oxide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.4.11 1.8.4.11] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lwl OCA], [http://pdbe.org/4lwl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lwl RCSB], [http://www.ebi.ac.uk/pdbsum/4lwl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lwl ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lwl OCA], [http://pdbe.org/4lwl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lwl RCSB], [http://www.ebi.ac.uk/pdbsum/4lwl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lwl ProSAT]</span></td></tr>
Line 25:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Alkoo]]
	[[Category: Hwang, K Y]]		[[Category: Hwang, K Y]]
	[[Category: Lee, E H]]		[[Category: Lee, E H]]
	[[Category: Alpha/beta fold]]		[[Category: Alpha/beta fold]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 21:43, 4 August 2016

OCA — Thu, 04 Aug 2016 21:43:01 GMT

←Older revision		Revision as of 21:43, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of methionine sulfoxide reductase U16C/E55A from clostridium oremlandii==		==Crystal structure of methionine sulfoxide reductase U16C/E55A from clostridium oremlandii==
	<StructureSection load='4lwl' size='340' side='right' caption='[[4lwl]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='4lwl' size='340' side='right' caption='[[4lwl]], [[Resolution\|resolution]] 1.60Å' scene=''>
Line 7:		Line 8:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4lwj\|4lwj]], [[4lwk\|4lwk]], [[4lwm\|4lwm]], [[4lwn\|4lwn]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4lwj\|4lwj]], [[4lwk\|4lwk]], [[4lwm\|4lwm]], [[4lwn\|4lwn]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide-methionine_(S)-S-oxide_reductase Peptide-methionine (S)-S-oxide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.4.11 1.8.4.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide-methionine_(S)-S-oxide_reductase Peptide-methionine (S)-S-oxide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.4.11 1.8.4.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lwl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lwl RCSB], [http://www.ebi.ac.uk/pdbsum/4lwl PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lwl OCA], [http://pdbe.org/4lwl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lwl RCSB], [http://www.ebi.ac.uk/pdbsum/4lwl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lwl ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4lwl" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:23, 25 December 2014

OCA — Thu, 25 Dec 2014 13:23:43 GMT

←Older revision		Revision as of 13:23, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4lwl]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LWL FirstGlance]. <br>		<table><tr><td colspan='2'>[[4lwl]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LWL FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4lwj\|4lwj]], [[4lwk\|4lwk]], [[4lwm\|4lwm]], [[4lwn\|4lwn]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4lwj\|4lwj]], [[4lwk\|4lwk]], [[4lwm\|4lwm]], [[4lwn\|4lwn]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide-methionine_(S)-S-oxide_reductase Peptide-methionine (S)-S-oxide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.4.11 1.8.4.11] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide-methionine_(S)-S-oxide_reductase Peptide-methionine (S)-S-oxide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.4.11 1.8.4.11] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lwl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lwl RCSB], [http://www.ebi.ac.uk/pdbsum/4lwl PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lwl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lwl RCSB], [http://www.ebi.ac.uk/pdbsum/4lwl PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/A8MI53_ALKOO A8MI53_ALKOO]] Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).[HAMAP-Rule:MF_01401]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Hwang, K Y.]]	+	[[Category: Hwang, K Y]]
-	[[Category: Lee, E H.]]	+	[[Category: Lee, E H]]
	[[Category: Alpha/beta fold]]		[[Category: Alpha/beta fold]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 08:46, 11 June 2014

OCA — Wed, 11 Jun 2014 08:46:52 GMT

←Older revision		Revision as of 08:46, 11 June 2014
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal structure of methionine sulfoxide reductase U16C/E55A from clostridium oremlandii==
		+	<StructureSection load='4lwl' size='340' side='right' caption='[[4lwl]], [[Resolution\|resolution]] 1.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4lwl]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LWL FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4lwj\|4lwj]], [[4lwk\|4lwk]], [[4lwm\|4lwm]], [[4lwn\|4lwn]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide-methionine_(S)-S-oxide_reductase Peptide-methionine (S)-S-oxide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.4.11 1.8.4.11] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lwl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lwl RCSB], [http://www.ebi.ac.uk/pdbsum/4lwl PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Methionine sulfoxide reductase A (MsrA) reduces free and protein-based methionine-S-sulfoxide to methionine. Structures of 1-Cys MsrAs lacking a resolving Cys, which interacts with catalytic Cys, are unknown. In addition, no structural information on selenocysteine (Sec)-containing MsrA enzymes has been reported. In this work, we determined the crystal structures of 1-Cys type selenoprotein MsrA from Clostridium oremlandii at 1.6-1.8A, including the reduced, oxidized (sulfenic acid), and substrate-bound forms. The overall structure of Clostridium MsrA, consisting of ten alpha-helices and six beta-strands, folds into a catalytic domain and a novel helical domain absent from other known MsrA structures. The helical domain, containing five helices, tightly interacts with the catalytic domain, and is likely critical for catalytic activity due to its association with organizing the active site. This helical domain is also conserved in several selenoprotein MsrAs. Our structural analysis reveals that the side chain length of Glu55 is critical for the proton donor function of this residue. Our structures also provide insights into the architecture of the 1-Cys MsrA active site and the roles of active site residues in substrate recognition and catalysis.

-	~~The entry 4lwl is ON HOLD until Paper Publication~~	+	Structural analysis of 1-Cys type selenoprotein methionine sulfoxide reductase A.,Lee EH, Kwak GH, Kim MJ, Kim HY, Hwang KY Arch Biochem Biophys. 2014 Mar 1;545:1-8. doi: 10.1016/j.abb.2013.12.024. Epub, 2014 Jan 8. PMID:24412203<ref>PMID:24412203</ref>

-	~~Authors~~: Hwang, K.Y., Lee, E.H.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Crystal structure of methionine sulfoxide reductase U16C~~/~~E55A from clostridium oremlandii~~	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Hwang, K Y.]]
		+	[[Category: Lee, E H.]]
		+	[[Category: Alpha/beta fold]]
		+	[[Category: Oxidoreductase]]

OCA at 07:20, 14 August 2013

OCA — Wed, 14 Aug 2013 07:20:18 GMT

←Older revision		Revision as of 07:20, 14 August 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4lwl is ON HOLD	+	The entry 4lwl is ON HOLD until Paper Publication

	Authors: Hwang, K.Y., Lee, E.H.		Authors: Hwang, K.Y., Lee, E.H.

-	Description: ~~CRYSTAL STRUCTURE OF METHIONINE SULFOXIDE REDUCTASE~~ U16C/E55A ~~FROM CLOSTRIDIUM OREMLANDII~~	+	Description: Crystal structure of methionine sulfoxide reductase U16C/E55A from clostridium oremlandii

OCA: Protected "4lwl" [edit=sysop:move=sysop]

OCA — Wed, 07 Aug 2013 20:18:16 GMT

Protected "4lwl" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:18, 7 August 2013

OCA: New page: '''Unreleased structure''' The entry 4lwl is ON HOLD Authors: Hwang, K.Y., Lee, E.H. Description: CRYSTAL STRUCTURE OF METHIONINE SULFOXIDE REDUCTASE U16C/E55A FROM CLOSTRIDIUM OREMLAN...

OCA — Wed, 07 Aug 2013 20:18:15 GMT

New page: '''Unreleased structure''' The entry 4lwl is ON HOLD Authors: Hwang, K.Y., Lee, E.H. Description: CRYSTAL STRUCTURE OF METHIONINE SULFOXIDE REDUCTASE U16C/E55A FROM CLOSTRIDIUM OREMLAN...

New page

'''Unreleased structure'''

The entry 4lwl is ON HOLD

Authors: Hwang, K.Y., Lee, E.H.

Description: CRYSTAL STRUCTURE OF METHIONINE SULFOXIDE REDUCTASE U16C/E55A FROM CLOSTRIDIUM OREMLANDII