4m27 - Revision history

OCA at 14:40, 8 November 2023

OCA — Wed, 08 Nov 2023 14:40:07 GMT

←Older revision		Revision as of 14:40, 8 November 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4m27]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_lavendulae_subsp._lavendulae Streptomyces lavendulae subsp. lavendulae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M27 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M27 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4m27]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_lavendulae_subsp._lavendulae Streptomyces lavendulae subsp. lavendulae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M27 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M27 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.35Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m27 OCA], [https://pdbe.org/4m27 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m27 RCSB], [https://www.ebi.ac.uk/pdbsum/4m27 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m27 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m27 OCA], [https://pdbe.org/4m27 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m27 RCSB], [https://www.ebi.ac.uk/pdbsum/4m27 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m27 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 10:48, 21 December 2022

OCA — Wed, 21 Dec 2022 10:48:27 GMT

←Older revision		Revision as of 10:48, 21 December 2022
Line 3:		Line 3:
	<StructureSection load='4m27' size='340' side='right'caption='[[4m27]], [[Resolution\|resolution]] 2.35Å' scene=''>		<StructureSection load='4m27' size='340' side='right'caption='[[4m27]], [[Resolution\|resolution]] 2.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4m27]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Streptomyces_lavendulae_subsp._lavendulae Streptomyces lavendulae subsp. lavendulae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M27 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=4M27 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4m27]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_lavendulae_subsp._lavendulae Streptomyces lavendulae subsp. lavendulae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M27 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M27 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4m23\|4m23]], [[4m25\|4m25]], [[4m26\|4m26]], [[4m2c\|4m2c]], [[4m2e\|4m2e]], [[4m2f\|4m2f]], [[4m2g\|4m2g]], [[4m2i\|4m2i]], [[4m2j\|4m2j]], [[4m2k\|4m2k]], [[4m2m\|4m2m]]</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m27 OCA], [https://pdbe.org/4m27 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m27 RCSB], [https://www.ebi.ac.uk/pdbsum/4m27 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m27 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=4m27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m27 OCA], [~~http~~://pdbe.org/4m27 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4m27 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4m27 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4m27 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/G9MBV2_STRLA G9MBV2_STRLA]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 27:
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Streptomyces lavendulae subsp. lavendulae]]		[[Category: Streptomyces lavendulae subsp. lavendulae]]
-	[[Category: Chang~~, C Y~~]]	+	[[Category: Chang CY]]
-	[[Category: Li~~, T L~~]]	+	[[Category: Li TL]]
-	[[Category: Liu~~, Y C~~]]	+	[[Category: Liu YC]]
-	[[Category: Lyu~~, S Y~~]]	+	[[Category: Lyu SY]]
-	[[Category: Wu~~, C C]]~~	+	[[Category: Wu CC]]
-	~~[[Category: Fe binding]]~~	+
-	~~[[Category: Hydroxylase]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 06:38, 22 April 2020

OCA — Wed, 22 Apr 2020 06:38:07 GMT

←Older revision		Revision as of 06:38, 22 April 2020
Line 1:		Line 1:

	==Crystal structure of non-heme iron oxygenase OrfP in complex with Fe and L-Arg==		==Crystal structure of non-heme iron oxygenase OrfP in complex with Fe and L-Arg==
-	<StructureSection load='4m27' size='340' side='right' caption='[[4m27]], [[Resolution\|resolution]] 2.35Å' scene=''>	+	<StructureSection load='4m27' size='340' side='right'caption='[[4m27]], [[Resolution\|resolution]] 2.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4m27]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_lavendulae_subsp._lavendulae Streptomyces lavendulae subsp. lavendulae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M27 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4M27 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4m27]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_lavendulae_subsp._lavendulae Streptomyces lavendulae subsp. lavendulae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M27 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4M27 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4m23\|4m23]], [[4m25\|4m25]], [[4m26\|4m26]], [[4m2c\|4m2c]], [[4m2e\|4m2e]], [[4m2f\|4m2f]], [[4m2g\|4m2g]], [[4m2i\|4m2i]], [[4m2j\|4m2j]], [[4m2k\|4m2k]], [[4m2m\|4m2m]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4m23\|4m23]], [[4m25\|4m25]], [[4m26\|4m26]], [[4m2c\|4m2c]], [[4m2e\|4m2e]], [[4m2f\|4m2f]], [[4m2g\|4m2g]], [[4m2i\|4m2i]], [[4m2j\|4m2j]], [[4m2k\|4m2k]], [[4m2m\|4m2m]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4m27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m27 OCA], [http://pdbe.org/4m27 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4m27 RCSB], [http://www.ebi.ac.uk/pdbsum/4m27 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4m27 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4m27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m27 OCA], [http://pdbe.org/4m27 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4m27 RCSB], [http://www.ebi.ac.uk/pdbsum/4m27 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4m27 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 17:		Line 17:
	</div>		</div>
	<div class="pdbe-citations 4m27" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4m27" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Hydroxylases 3D structures\|Hydroxylases 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Streptomyces lavendulae subsp. lavendulae]]		[[Category: Streptomyces lavendulae subsp. lavendulae]]
	[[Category: Chang, C Y]]		[[Category: Chang, C Y]]

OCA at 08:33, 18 July 2018

OCA — Wed, 18 Jul 2018 08:33:03 GMT

←Older revision		Revision as of 08:33, 18 July 2018
Line 3:		Line 3:
	<StructureSection load='4m27' size='340' side='right' caption='[[4m27]], [[Resolution\|resolution]] 2.35Å' scene=''>		<StructureSection load='4m27' size='340' side='right' caption='[[4m27]], [[Resolution\|resolution]] 2.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4m27]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M27 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M27 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4m27]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_lavendulae_subsp._lavendulae Streptomyces lavendulae subsp. lavendulae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M27 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M27 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4m23\|4m23]], [[4m25\|4m25]], [[4m26\|4m26]], [[4m2c\|4m2c]], [[4m2e\|4m2e]], [[4m2f\|4m2f]], [[4m2g\|4m2g]], [[4m2i\|4m2i]], [[4m2j\|4m2j]], [[4m2k\|4m2k]], [[4m2m\|4m2m]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4m23\|4m23]], [[4m25\|4m25]], [[4m26\|4m26]], [[4m2c\|4m2c]], [[4m2e\|4m2e]], [[4m2f\|4m2f]], [[4m2g\|4m2g]], [[4m2i\|4m2i]], [[4m2j\|4m2j]], [[4m2k\|4m2k]], [[4m2m\|4m2m]]</td></tr>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Streptomyces lavendulae subsp. lavendulae]]
	[[Category: Chang, C Y]]		[[Category: Chang, C Y]]
	[[Category: Li, T L]]		[[Category: Li, T L]]

OCA at 07:50, 11 August 2016

OCA — Thu, 11 Aug 2016 07:50:21 GMT

←Older revision		Revision as of 07:50, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of non-heme iron oxygenase OrfP in complex with Fe and L-Arg==		==Crystal structure of non-heme iron oxygenase OrfP in complex with Fe and L-Arg==
	<StructureSection load='4m27' size='340' side='right' caption='[[4m27]], [[Resolution\|resolution]] 2.35Å' scene=''>		<StructureSection load='4m27' size='340' side='right' caption='[[4m27]], [[Resolution\|resolution]] 2.35Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4m23\|4m23]], [[4m25\|4m25]], [[4m26\|4m26]], [[4m2c\|4m2c]], [[4m2e\|4m2e]], [[4m2f\|4m2f]], [[4m2g\|4m2g]], [[4m2i\|4m2i]], [[4m2j\|4m2j]], [[4m2k\|4m2k]], [[4m2m\|4m2m]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4m23\|4m23]], [[4m25\|4m25]], [[4m26\|4m26]], [[4m2c\|4m2c]], [[4m2e\|4m2e]], [[4m2f\|4m2f]], [[4m2g\|4m2g]], [[4m2i\|4m2i]], [[4m2j\|4m2j]], [[4m2k\|4m2k]], [[4m2m\|4m2m]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m27 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m27 RCSB], [http://www.ebi.ac.uk/pdbsum/4m27 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m27 OCA], [http://pdbe.org/4m27 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4m27 RCSB], [http://www.ebi.ac.uk/pdbsum/4m27 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4m27 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4m27" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:00, 5 January 2015

OCA — Mon, 05 Jan 2015 09:00:26 GMT

←Older revision		Revision as of 09:00, 5 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4m27]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M27 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M27 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4m27]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M27 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M27 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4m23\|4m23]], [[4m25\|4m25]], [[4m26\|4m26]], [[4m2c\|4m2c]], [[4m2e\|4m2e]], [[4m2f\|4m2f]], [[4m2g\|4m2g]], [[4m2i\|4m2i]], [[4m2j\|4m2j]], [[4m2k\|4m2k]], [[4m2m\|4m2m]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4m23\|4m23]], [[4m25\|4m25]], [[4m26\|4m26]], [[4m2c\|4m2c]], [[4m2e\|4m2e]], [[4m2f\|4m2f]], [[4m2g\|4m2g]], [[4m2i\|4m2i]], [[4m2j\|4m2j]], [[4m2k\|4m2k]], [[4m2m\|4m2m]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m27 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m27 RCSB], [http://www.ebi.ac.uk/pdbsum/4m27 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m27 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m27 RCSB], [http://www.ebi.ac.uk/pdbsum/4m27 PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Chang, C Y.]]	+	[[Category: Chang, C Y]]
-	[[Category: Li, T L.]]	+	[[Category: Li, T L]]
-	[[Category: Liu, Y C.]]	+	[[Category: Liu, Y C]]
-	[[Category: Lyu, S Y.]]	+	[[Category: Lyu, S Y]]
-	[[Category: Wu, C C.]]	+	[[Category: Wu, C C]]
	[[Category: Fe binding]]		[[Category: Fe binding]]
	[[Category: Hydroxylase]]		[[Category: Hydroxylase]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 06:27, 25 June 2014

OCA — Wed, 25 Jun 2014 06:27:51 GMT

←Older revision		Revision as of 06:27, 25 June 2014
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-	'''~~Unreleased~~ structure'''	+	==Crystal structure of non-heme iron oxygenase OrfP in complex with Fe and L-Arg==
		+	<StructureSection load='4m27' size='340' side='right' caption='[[4m27]], [[Resolution\|resolution]] 2.35Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4m27]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M27 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M27 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4m23\|4m23]], [[4m25\|4m25]], [[4m26\|4m26]], [[4m2c\|4m2c]], [[4m2e\|4m2e]], [[4m2f\|4m2f]], [[4m2g\|4m2g]], [[4m2i\|4m2i]], [[4m2j\|4m2j]], [[4m2k\|4m2k]], [[4m2m\|4m2m]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m27 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m27 RCSB], [http://www.ebi.ac.uk/pdbsum/4m27 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Streptothricin-F (STT-F), one of the early-discovered antibiotics, consists of three components, a beta-lysine homopolymer, an aminosugar D-gulosamine, and an unusual bicyclic streptolidine. The biosynthesis of streptolidine is a long-lasting but unresolved puzzle. Herein, a combination of genetic/biochemical/structural approaches was used to unravel this problem. The STT gene cluster was first sequenced from a Streptomyces variant BCRC 12163, wherein two gene products OrfP and OrfR were characterized in vitro to be a dihydroxylase and a cyclase, respectively. Thirteen high-resolution crystal structures for both enzymes in different reaction intermediate states were snapshotted to help elucidate their catalytic mechanisms. OrfP catalyzes an Fe(II) -dependent double hydroxylation reaction converting L-Arg into (3R,4R)-(OH)2 -L-Arg via (3S)-OH-L-Arg, while OrfR catalyzes an unusual PLP-dependent elimination/addition reaction cyclizing (3R,4R)-(OH)2 -L-Arg to the six-membered (4R)-OH-capreomycidine. The biosynthetic mystery finally comes to light as the latter product was incorporation into STT-F by a feeding experiment.

-	~~The entry 4m27 is ON HOLD until Paper Publication~~	+	Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.,Chang CY, Lyu SY, Liu YC, Hsu NS, Wu CC, Tang CF, Lin KH, Ho JY, Wu CJ, Tsai MD, Li TL Angew Chem Int Ed Engl. 2014 Feb 10;53(7):1943-8. doi: 10.1002/anie.201307989., Epub 2014 Jan 21. PMID:24505011<ref>PMID:24505011</ref>

-	~~Authors~~: Chang, C.Y., Liu, Y.C., Lyu, S.Y., Wu, C.C.~~, Li, T.L.~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Crystal structure of non-heme iron oxygenase OrfP in complex with~~ Fe ~~and L-Arg~~	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Chang, C Y.]]
		+	[[Category: Li, T L.]]
		+	[[Category: Liu, Y C.]]
		+	[[Category: Lyu, S Y.]]
		+	[[Category: Wu, C C.]]
		+	[[Category: Fe binding]]
		+	[[Category: Hydroxylase]]
		+	[[Category: Oxidoreductase]]

OCA at 04:46, 12 September 2013

OCA — Thu, 12 Sep 2013 04:46:49 GMT

←Older revision		Revision as of 04:46, 12 September 2013
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4m27 is ON HOLD	+	The entry 4m27 is ON HOLD until Paper Publication

	Authors: Chang, C.Y., Liu, Y.C., Lyu, S.Y., Wu, C.C., Li, T.L.		Authors: Chang, C.Y., Liu, Y.C., Lyu, S.Y., Wu, C.C., Li, T.L.

	Description: Crystal structure of non-heme iron oxygenase OrfP in complex with Fe and L-Arg		Description: Crystal structure of non-heme iron oxygenase OrfP in complex with Fe and L-Arg

OCA: Protected "4m27" [edit=sysop:move=sysop]

OCA — Wed, 14 Aug 2013 07:23:05 GMT

Protected "4m27" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:23, 14 August 2013

OCA: New page: '''Unreleased structure''' The entry 4m27 is ON HOLD Authors: Chang, C.Y., Liu, Y.C., Lyu, S.Y., Wu, C.C., Li, T.L. Description: Crystal structure of non-heme iron oxygenase OrfP in co...

OCA — Wed, 14 Aug 2013 07:23:03 GMT

New page: '''Unreleased structure''' The entry 4m27 is ON HOLD Authors: Chang, C.Y., Liu, Y.C., Lyu, S.Y., Wu, C.C., Li, T.L. Description: Crystal structure of non-heme iron oxygenase OrfP in co...

New page

'''Unreleased structure'''

The entry 4m27 is ON HOLD

Authors: Chang, C.Y., Liu, Y.C., Lyu, S.Y., Wu, C.C., Li, T.L.

Description: Crystal structure of non-heme iron oxygenase OrfP in complex with Fe and L-Arg