4m5d - Revision history

OCA at 08:55, 20 March 2024

OCA — Wed, 20 Mar 2024 08:55:57 GMT

←Older revision		Revision as of 08:55, 20 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4m5d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M5D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M5D FirstGlance]. <br>		<table><tr><td colspan='2'>[[4m5d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M5D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M5D FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.97Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m5d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m5d OCA], [https://pdbe.org/4m5d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m5d RCSB], [https://www.ebi.ac.uk/pdbsum/4m5d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m5d ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m5d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m5d OCA], [https://pdbe.org/4m5d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m5d RCSB], [https://www.ebi.ac.uk/pdbsum/4m5d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m5d ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/UTP22_YEAST UTP22_YEAST] Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.<ref>PMID:15590835</ref>		[https://www.uniprot.org/uniprot/UTP22_YEAST UTP22_YEAST] Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.<ref>PMID:15590835</ref>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	A multitude of proteins and small nucleolar RNAs transiently associate with eukaryotic ribosomal RNAs to direct their modification and processing and the assembly of ribosomal proteins. Utp22 and Rrp7, two interacting proteins with no recognizable domain, are components of the 90S preribosome or the small subunit processome that conducts early processing of 18S rRNA. Here, we determine the cocrystal structure of Utp22 and Rrp7 complex at 1.97 A resolution and the NMR structure of a C-terminal fragment of Rrp7, which is not visible in the crystal structure. The structure reveals that Utp22 surprisingly resembles a dimeric class I tRNA CCA-adding enzyme yet with degenerate active sites, raising an interesting evolutionary connection between tRNA and rRNA processing machineries. Rrp7 binds extensively to Utp22 using a deviant RNA recognition motif and an extended linker. Functional sites on the two proteins were identified by structure-based mutagenesis in yeast. We show that Rrp7 contains a flexible RNA-binding C-terminal tail that is essential for association with preribosomes. RNA-protein crosslinking shows that Rrp7 binds at the central domain of 18S rRNA and shares a neighborhood with two processing H/ACA snoRNAs snR30 and snR10. Depletion of snR30 prevents the stable assembly of Rrp7 into preribosomes. Our results provide insight into the evolutionary origin and functional context of Utp22 and Rrp7.
-
-	An RNA-Binding Complex Involved in Ribosome Biogenesis Contains a Protein with Homology to tRNA CCA-Adding Enzyme.,Lin J, Lu J, Feng Y, Sun M, Ye K PLoS Biol. 2013 Oct;11(10):e1001669. doi: 10.1371/journal.pbio.1001669. Epub 2013, Oct 1. PMID:24130456<ref>PMID:24130456</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4m5d" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:57, 21 December 2022

OCA — Wed, 21 Dec 2022 10:57:06 GMT

←Older revision		Revision as of 10:57, 21 December 2022
Line 1:		Line 1:

	==Crystal structure of the Utp22 and Rrp7 complex from Saccharomyces cerevisiae==		==Crystal structure of the Utp22 and Rrp7 complex from Saccharomyces cerevisiae==
-	<StructureSection load='4m5d' size='340' side='right' caption='[[4m5d]], [[Resolution\|resolution]] 1.97Å' scene=''>	+	<StructureSection load='4m5d' size='340' side='right'caption='[[4m5d]], [[Resolution\|resolution]] 1.97Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4m5d]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Baker's_yeast Baker's yeast~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M5D OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4M5D FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4m5d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M5D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M5D FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">UTP22, YGR090W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast]), RRP7, YCL031C, YCL184, YCL31C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m5d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m5d OCA], [https://pdbe.org/4m5d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m5d RCSB], [https://www.ebi.ac.uk/pdbsum/4m5d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m5d ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4m5d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m5d OCA], [~~http~~://pdbe.org/4m5d PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4m5d RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4m5d PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4m5d ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/UTP22_YEAST UTP22_YEAST]] Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.<ref>PMID:15590835</ref> [[http://www.uniprot.org/uniprot/RRP7_YEAST RRP7_YEAST]] Plays an important role in the synthesis of 18S rRNA but is not required for the 5.8S and 25S pathway. Is necessary for the cleavage at site A2. Is required for efficient association of RPS27 with the pre-ribosomal particle.	+	[https://www.uniprot.org/uniprot/UTP22_YEAST UTP22_YEAST] Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.<ref>PMID:15590835</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Baker's yeast~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Lin, J~~]]	+	[[Category: Saccharomyces cerevisiae S288C]]
-	[[Category: ~~Ye, K~~]]	+	[[Category: Lin J]]
-	[[Category: ~~Nucleolus]]~~	+	[[Category: Ye K]]
-	~~[[Category: Rna binding protein~~]]	+

OCA at 22:07, 5 August 2016

OCA — Fri, 05 Aug 2016 22:07:14 GMT

←Older revision		Revision as of 22:07, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of the Utp22 and Rrp7 complex from Saccharomyces cerevisiae==		==Crystal structure of the Utp22 and Rrp7 complex from Saccharomyces cerevisiae==
	<StructureSection load='4m5d' size='340' side='right' caption='[[4m5d]], [[Resolution\|resolution]] 1.97Å' scene=''>		<StructureSection load='4m5d' size='340' side='right' caption='[[4m5d]], [[Resolution\|resolution]] 1.97Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4m5d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M5D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M5D FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4m5d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M5D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M5D FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">UTP22, YGR090W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 ~~Saccharomyces cerevisiae S288c~~]), RRP7, YCL031C, YCL184, YCL31C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 ~~Saccharomyces cerevisiae S288c~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">UTP22, YGR090W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast]), RRP7, YCL031C, YCL184, YCL31C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m5d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m5d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m5d RCSB], [http://www.ebi.ac.uk/pdbsum/4m5d PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m5d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m5d OCA], [http://pdbe.org/4m5d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4m5d RCSB], [http://www.ebi.ac.uk/pdbsum/4m5d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4m5d ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4m5d" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Saccharomyces cerevisiae s288c~~]]	+	[[Category: Baker's yeast]]
	[[Category: Lin, J]]		[[Category: Lin, J]]
	[[Category: Ye, K]]		[[Category: Ye, K]]
	[[Category: Nucleolus]]		[[Category: Nucleolus]]
	[[Category: Rna binding protein]]		[[Category: Rna binding protein]]

OCA at 06:15, 25 December 2014

OCA — Thu, 25 Dec 2014 06:15:09 GMT

←Older revision		Revision as of 06:15, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m5d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m5d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m5d RCSB], [http://www.ebi.ac.uk/pdbsum/4m5d PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m5d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m5d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m5d RCSB], [http://www.ebi.ac.uk/pdbsum/4m5d PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/UTP22_YEAST UTP22_YEAST]] Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.<ref>PMID:15590835</ref> [[http://www.uniprot.org/uniprot/RRP7_YEAST RRP7_YEAST]] Plays an important role in the synthesis of 18S rRNA but is not required for the 5.8S and 25S pathway. Is necessary for the cleavage at site A2. Is required for efficient association of RPS27 with the pre-ribosomal particle.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 15:01, 21 December 2014

OCA — Sun, 21 Dec 2014 15:01:59 GMT

←Older revision		Revision as of 15:01, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4m5d\| PDB=4m5d \| SCENE= }}~~	+	==Crystal structure of the Utp22 and Rrp7 complex from Saccharomyces cerevisiae==
-	===Crystal structure of the Utp22 and Rrp7 complex from Saccharomyces cerevisiae===	+	<StructureSection load='4m5d' size='340' side='right' caption='[[4m5d]], [[Resolution\|resolution]] 1.97Å' scene=''>
-	~~{{ABSTRACT_PUBMED_24130456}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4m5d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M5D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M5D FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">UTP22, YGR090W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Saccharomyces cerevisiae S288c]), RRP7, YCL031C, YCL184, YCL31C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Saccharomyces cerevisiae S288c])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m5d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m5d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m5d RCSB], [http://www.ebi.ac.uk/pdbsum/4m5d PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	A multitude of proteins and small nucleolar RNAs transiently associate with eukaryotic ribosomal RNAs to direct their modification and processing and the assembly of ribosomal proteins. Utp22 and Rrp7, two interacting proteins with no recognizable domain, are components of the 90S preribosome or the small subunit processome that conducts early processing of 18S rRNA. Here, we determine the cocrystal structure of Utp22 and Rrp7 complex at 1.97 A resolution and the NMR structure of a C-terminal fragment of Rrp7, which is not visible in the crystal structure. The structure reveals that Utp22 surprisingly resembles a dimeric class I tRNA CCA-adding enzyme yet with degenerate active sites, raising an interesting evolutionary connection between tRNA and rRNA processing machineries. Rrp7 binds extensively to Utp22 using a deviant RNA recognition motif and an extended linker. Functional sites on the two proteins were identified by structure-based mutagenesis in yeast. We show that Rrp7 contains a flexible RNA-binding C-terminal tail that is essential for association with preribosomes. RNA-protein crosslinking shows that Rrp7 binds at the central domain of 18S rRNA and shares a neighborhood with two processing H/ACA snoRNAs snR30 and snR10. Depletion of snR30 prevents the stable assembly of Rrp7 into preribosomes. Our results provide insight into the evolutionary origin and functional context of Utp22 and Rrp7.

-	~~==Function==~~	+	An RNA-Binding Complex Involved in Ribosome Biogenesis Contains a Protein with Homology to tRNA CCA-Adding Enzyme.,Lin J, Lu J, Feng Y, Sun M, Ye K PLoS Biol. 2013 Oct;11(10):e1001669. doi: 10.1371/journal.pbio.1001669. Epub 2013, Oct 1. PMID:24130456<ref>PMID:24130456</ref>
-	~~[[http~~:~~//www~~.~~uniprot~~.~~org~~/~~uniprot/UTP22_YEAST UTP22_YEAST]] Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly~~.<ref>PMID:~~15590835~~</ref> [[http://www.uniprot.org/uniprot/RRP7_YEAST RRP7_YEAST]] Plays an important role in the synthesis of 18S rRNA but is not required for the 5.8S and 25S pathway. Is necessary for the cleavage at site A2. Is required for efficient association of RPS27 with the pre-ribosomal particle.	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[4m5d]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4M5D OCA].~~	+	</div>
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:024130456</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Saccharomyces cerevisiae s288c]]		[[Category: Saccharomyces cerevisiae s288c]]
-	[[Category: Lin, J.]]	+	[[Category: Lin, J]]
-	[[Category: Ye, K.]]	+	[[Category: Ye, K]]
	[[Category: Nucleolus]]		[[Category: Nucleolus]]
	[[Category: Rna binding protein]]		[[Category: Rna binding protein]]

OCA at 07:52, 6 November 2013

OCA — Wed, 06 Nov 2013 07:52:31 GMT

←Older revision		Revision as of 07:52, 6 November 2013
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_4m5d\| PDB=4m5d \| SCENE= }}
		+	===Crystal structure of the Utp22 and Rrp7 complex from Saccharomyces cerevisiae===
		+	{{ABSTRACT_PUBMED_24130456}}

-	~~The entry 4m5d is ON HOLD~~ ~~until Paper Publication~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/UTP22_YEAST UTP22_YEAST]] Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.<ref>PMID:15590835</ref> [[http://www.uniprot.org/uniprot/RRP7_YEAST RRP7_YEAST]] Plays an important role in the synthesis of 18S rRNA but is not required for the 5.8S and 25S pathway. Is necessary for the cleavage at site A2. Is required for efficient association of RPS27 with the pre-ribosomal particle.

-	~~Authors~~: ~~Lin, J~~.~~, Ye, K~~.	+	==About this Structure==
		+	[[4m5d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M5D OCA].

-	~~Description~~: ~~Crystal structure of the Utp22 and Rrp7 complex from~~ Saccharomyces cerevisiae	+	==Reference==
		+	<ref group="xtra">PMID:024130456</ref><references group="xtra"/><references/>
		+	[[Category: Saccharomyces cerevisiae s288c]]
		+	[[Category: Lin, J.]]
		+	[[Category: Ye, K.]]
		+	[[Category: Nucleolus]]
		+	[[Category: Rna binding protein]]

OCA at 07:33, 29 September 2013

OCA — Sun, 29 Sep 2013 07:33:34 GMT

←Older revision		Revision as of 07:33, 29 September 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4m5d is ON HOLD	+	The entry 4m5d is ON HOLD until Paper Publication

	Authors: Lin, J., Ye, K.		Authors: Lin, J., Ye, K.

	Description: Crystal structure of the Utp22 and Rrp7 complex from Saccharomyces cerevisiae		Description: Crystal structure of the Utp22 and Rrp7 complex from Saccharomyces cerevisiae

OCA: Protected "4m5d" [edit=sysop:move=sysop]

OCA — Wed, 14 Aug 2013 07:27:21 GMT

Protected "4m5d" [edit=sysop:move=sysop]

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Revision as of 07:27, 14 August 2013

OCA: New page: '''Unreleased structure''' The entry 4m5d is ON HOLD Authors: Lin, J., Ye, K. Description: Crystal structure of the Utp22 and Rrp7 complex from Saccharomyces cerevisiae

OCA — Wed, 14 Aug 2013 07:27:20 GMT

New page: '''Unreleased structure''' The entry 4m5d is ON HOLD Authors: Lin, J., Ye, K. Description: Crystal structure of the Utp22 and Rrp7 complex from Saccharomyces cerevisiae

New page

'''Unreleased structure'''

The entry 4m5d is ON HOLD

Authors: Lin, J., Ye, K.

Description: Crystal structure of the Utp22 and Rrp7 complex from Saccharomyces cerevisiae