4m84 - Revision history

OCA at 16:34, 20 September 2023

OCA — Wed, 20 Sep 2023 16:34:05 GMT

←Older revision		Revision as of 16:34, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4m84]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M84 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M84 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4m84]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M84 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M84 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=21E:5-AMINO-1-TERT-BUTYL-3-(QUINOLIN-2-YL)-1H-PYRAZOLE-4-CARBOXAMIDE'>21E</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.998Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=21E:5-AMINO-1-TERT-BUTYL-3-(QUINOLIN-2-YL)-1H-PYRAZOLE-4-CARBOXAMIDE'>21E</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m84 OCA], [https://pdbe.org/4m84 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m84 RCSB], [https://www.ebi.ac.uk/pdbsum/4m84 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m84 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m84 OCA], [https://pdbe.org/4m84 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m84 RCSB], [https://www.ebi.ac.uk/pdbsum/4m84 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m84 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 11:02, 21 December 2022

OCA — Wed, 21 Dec 2022 11:02:03 GMT

←Older revision		Revision as of 11:02, 21 December 2022
Line 1:		Line 1:

	==Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1455==		==Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1455==
-	<StructureSection load='4m84' size='340' side='right' caption='[[4m84]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='4m84' size='340' side='right'caption='[[4m84]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4m84]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Toxgo Toxgo~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M84 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4M84 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4m84]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M84 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M84 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=21E:5-AMINO-1-TERT-BUTYL-3-(QUINOLIN-2-YL)-1H-PYRAZOLE-4-CARBOXAMIDE'>21E</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=21E:5-AMINO-1-TERT-BUTYL-3-(QUINOLIN-2-YL)-1H-PYRAZOLE-4-CARBOXAMIDE'>21E</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AAG53993, CDPK1, TGGT1_059880, TGVEG_042030 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5811 TOXGO])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m84 OCA], [https://pdbe.org/4m84 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m84 RCSB], [https://www.ebi.ac.uk/pdbsum/4m84 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m84 ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium/calmodulin-dependent_protein_kinase Calcium/calmodulin-dependent protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.17 2.7.11.17] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4m84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m84 OCA], [~~http~~://pdbe.org/4m84 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4m84 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4m84 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4m84 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9BJF5_TOXGO Q9BJF5_TOXGO]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Calcium/calmodulin-dependent protein kinase~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Toxgo~~]]	+	[[Category: Toxoplasma gondii]]
-	[[Category: Merritt~~, E A]]~~	+	[[Category: Merritt EA]]
-	~~[[Category: Atp-binding]]~~	+
-	~~[[Category: Bumped kinase inhibitor]]~~	+
-	~~[[Category: Calcium-binding]]~~	+
-	~~[[Category: Serine/threonine protein kinase]]~~	+
-	~~[[Category: Transferase]]~~	+
-	~~[[Category: Transferase-transferase inhibitor complex~~]]	+

OCA at 11:39, 11 August 2016

OCA — Thu, 11 Aug 2016 11:39:36 GMT

←Older revision		Revision as of 11:39, 11 August 2016
Line 1:		Line 1:
		+
	==Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1455==		==Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1455==
	<StructureSection load='4m84' size='340' side='right' caption='[[4m84]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4m84' size='340' side='right' caption='[[4m84]], [[Resolution\|resolution]] 2.00Å' scene=''>
Line 6:		Line 7:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AAG53993, CDPK1, TGGT1_059880, TGVEG_042030 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5811 TOXGO])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AAG53993, CDPK1, TGGT1_059880, TGVEG_042030 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5811 TOXGO])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium/calmodulin-dependent_protein_kinase Calcium/calmodulin-dependent protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.17 2.7.11.17] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium/calmodulin-dependent_protein_kinase Calcium/calmodulin-dependent protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.17 2.7.11.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m84 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m84 RCSB], [http://www.ebi.ac.uk/pdbsum/4m84 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m84 OCA], [http://pdbe.org/4m84 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4m84 RCSB], [http://www.ebi.ac.uk/pdbsum/4m84 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4m84 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4m84" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:18, 5 January 2015

OCA — Mon, 05 Jan 2015 09:18:21 GMT

←Older revision		Revision as of 09:18, 5 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4m84]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxgo Toxgo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M84 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M84 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4m84]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxgo Toxgo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M84 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M84 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=21E:5-AMINO-1-TERT-BUTYL-3-(QUINOLIN-2-YL)-1H-PYRAZOLE-4-CARBOXAMIDE'>21E</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=21E:5-AMINO-1-TERT-BUTYL-3-(QUINOLIN-2-YL)-1H-PYRAZOLE-4-CARBOXAMIDE'>21E</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AAG53993, CDPK1, TGGT1_059880, TGVEG_042030 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5811 TOXGO])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AAG53993, CDPK1, TGGT1_059880, TGVEG_042030 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5811 TOXGO])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium/calmodulin-dependent_protein_kinase Calcium/calmodulin-dependent protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.17 2.7.11.17] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium/calmodulin-dependent_protein_kinase Calcium/calmodulin-dependent protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.17 2.7.11.17] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m84 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m84 RCSB], [http://www.ebi.ac.uk/pdbsum/4m84 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m84 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m84 RCSB], [http://www.ebi.ac.uk/pdbsum/4m84 PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 14:		Line 14:
	Potent and selective inhibitors of CDPK1 from and based on a 5-aminopyrazole-4-carboxamide scaffold.,Zhang Z, Ojo KK, Vidadala R, Huang W, Geiger JA, Scheele S, Choi R, Reid MC, Keyloun KR, Rivas K, Siddaramaiah LK, Comess KM, Robinson KP, Merta PJ, Kifle L, Hol WG, Parsons M, Merritt EA, Maly DJ, Verlinde CL, Van Voorhis WC, Fan E ACS Med Chem Lett. 2014 Jan 9;5(1):40-44. PMID:24494061<ref>PMID:24494061</ref>		Potent and selective inhibitors of CDPK1 from and based on a 5-aminopyrazole-4-carboxamide scaffold.,Zhang Z, Ojo KK, Vidadala R, Huang W, Geiger JA, Scheele S, Choi R, Reid MC, Keyloun KR, Rivas K, Siddaramaiah LK, Comess KM, Robinson KP, Merta PJ, Kifle L, Hol WG, Parsons M, Merritt EA, Maly DJ, Verlinde CL, Van Voorhis WC, Fan E ACS Med Chem Lett. 2014 Jan 9;5(1):40-44. PMID:24494061<ref>PMID:24494061</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 22:		Line 22:
	[[Category: Calcium/calmodulin-dependent protein kinase]]		[[Category: Calcium/calmodulin-dependent protein kinase]]
	[[Category: Toxgo]]		[[Category: Toxgo]]
-	[[Category: Merritt, E A.]]	+	[[Category: Merritt, E A]]
	[[Category: Atp-binding]]		[[Category: Atp-binding]]
	[[Category: Bumped kinase inhibitor]]		[[Category: Bumped kinase inhibitor]]

OCA at 13:33, 18 May 2014

OCA — Sun, 18 May 2014 13:33:54 GMT

←Older revision		Revision as of 13:33, 18 May 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4m84\| PDB=4m84 \| SCENE= }}~~	+	==Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1455==
-	===Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1455===	+	<StructureSection load='4m84' size='340' side='right' caption='[[4m84]], [[Resolution\|resolution]] 2.00Å' scene=''>
-	~~{{ABSTRACT_PUBMED_22369268}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4m84]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxgo Toxgo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M84 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M84 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=21E:5-AMINO-1-TERT-BUTYL-3-(QUINOLIN-2-YL)-1H-PYRAZOLE-4-CARBOXAMIDE'>21E</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AAG53993, CDPK1, TGGT1_059880, TGVEG_042030 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5811 TOXGO])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium/calmodulin-dependent_protein_kinase Calcium/calmodulin-dependent protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.17 2.7.11.17] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m84 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m84 RCSB], [http://www.ebi.ac.uk/pdbsum/4m84 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	5-Aminopyrazole-4-carboxamide was used as an alternative scaffold to substitute for the pyrazolopyrimidine of a known "bumped kinase inhibitor" to create selective inhibitors of calcium-dependent protein kinase-1 from both Toxoplasma gondii and Cryptosporidium parvum. Compounds with low nanomolar inhibitory potencies against the target enzymes were obtained. The most selective inhibitors also exhibited submicromolar activities in T. gondii cell proliferation assays and were shown to be non-toxic to mammalian cells.

-	~~==About this Structure==~~	+	Potent and selective inhibitors of CDPK1 from and based on a 5-aminopyrazole-4-carboxamide scaffold.,Zhang Z, Ojo KK, Vidadala R, Huang W, Geiger JA, Scheele S, Choi R, Reid MC, Keyloun KR, Rivas K, Siddaramaiah LK, Comess KM, Robinson KP, Merta PJ, Kifle L, Hol WG, Parsons M, Merritt EA, Maly DJ, Verlinde CL, Van Voorhis WC, Fan E ACS Med Chem Lett. 2014 Jan 9;5(1):40-44. PMID:24494061<ref>PMID:24494061</ref>
-	~~[[4m84]] is~~ a 1 ~~chain structure with sequence from [http~~:~~//en~~.~~wikipedia.org/wiki/Toxgo Toxgo]. Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4M84 OCA].~~	+

-	==~~Reference~~==	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:022369268</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Calcium/calmodulin-dependent protein kinase]]		[[Category: Calcium/calmodulin-dependent protein kinase]]
	[[Category: Toxgo]]		[[Category: Toxgo]]

OCA at 08:27, 5 February 2014

OCA — Wed, 05 Feb 2014 08:27:16 GMT

←Older revision		Revision as of 08:27, 5 February 2014
Line 1:		Line 1:
	{{STRUCTURE_4m84\| PDB=4m84 \| SCENE= }}		{{STRUCTURE_4m84\| PDB=4m84 \| SCENE= }}
	===Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1455===		===Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1455===
-	{{~~ABSTRACT_PUBMED_20436472~~}}	+	{{ABSTRACT_PUBMED_22369268}}

	==About this Structure==		==About this Structure==
-	[[4m84]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Toxoplasma_gondii Toxoplasma gondii~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M84 OCA].	+	[[4m84]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxgo Toxgo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M84 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~020436472~~</ref><references group="xtra"/><references/>	+	<ref group="xtra">PMID:022369268</ref><references group="xtra"/><references/>
	[[Category: Calcium/calmodulin-dependent protein kinase]]		[[Category: Calcium/calmodulin-dependent protein kinase]]
-	[[Category: ~~Toxoplasma gondii~~]]	+	[[Category: Toxgo]]
	[[Category: Merritt, E A.]]		[[Category: Merritt, E A.]]
	[[Category: Atp-binding]]		[[Category: Atp-binding]]

OCA at 07:28, 2 October 2013

OCA — Wed, 02 Oct 2013 07:28:14 GMT

←Older revision		Revision as of 07:28, 2 October 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4m84\| PDB=4m84 \| SCENE= }}
		+	===Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1455===
		+	{{ABSTRACT_PUBMED_20436472}}

-	~~The entry~~ 4m84 is ~~ON HOLD~~	+	==About this Structure==
		+	[[4m84]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M84 OCA].

-	~~Authors~~: Merritt, E.A.	+	==Reference==
-		+	<ref group="xtra">PMID:020436472</ref><references group="xtra"/><references/>
-	~~Description~~: Calcium-~~Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with~~ inhibitor ~~UW1455~~	+	[[Category: Calcium/calmodulin-dependent protein kinase]]
		+	[[Category: Toxoplasma gondii]]
		+	[[Category: Merritt, E A.]]
		+	[[Category: Atp-binding]]
		+	[[Category: Bumped kinase inhibitor]]
		+	[[Category: Calcium-binding]]
		+	[[Category: Serine/threonine protein kinase]]
		+	[[Category: Transferase]]
		+	[[Category: Transferase-transferase inhibitor complex]]

OCA: Protected "4m84" [edit=sysop:move=sysop]

OCA — Wed, 21 Aug 2013 07:58:27 GMT

Protected "4m84" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:58, 21 August 2013

OCA: New page: '''Unreleased structure''' The entry 4m84 is ON HOLD Authors: Merritt, E.A. Description: Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor U...

OCA — Wed, 21 Aug 2013 07:58:27 GMT

New page: '''Unreleased structure''' The entry 4m84 is ON HOLD Authors: Merritt, E.A. Description: Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor U...

New page

'''Unreleased structure'''

The entry 4m84 is ON HOLD

Authors: Merritt, E.A.

Description: Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1455