4m9w - Revision history

OCA at 16:34, 20 September 2023

OCA — Wed, 20 Sep 2023 16:34:46 GMT

←Older revision		Revision as of 16:34, 20 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4m9w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arachis_hypogaea Arachis hypogaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M9W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M9W FirstGlance]. <br>		<table><tr><td colspan='2'>[[4m9w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arachis_hypogaea Arachis hypogaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M9W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M9W FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.95Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m9w OCA], [https://pdbe.org/4m9w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m9w RCSB], [https://www.ebi.ac.uk/pdbsum/4m9w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m9w ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m9w OCA], [https://pdbe.org/4m9w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m9w RCSB], [https://www.ebi.ac.uk/pdbsum/4m9w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m9w ProSAT]</span></td></tr>
	</table>		</table>

OCA at 11:05, 21 December 2022

OCA — Wed, 21 Dec 2022 11:05:13 GMT

←Older revision		Revision as of 11:05, 21 December 2022
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	<StructureSection load='4m9w' size='340' side='right'caption='[[4m9w]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='4m9w' size='340' side='right'caption='[[4m9w]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4m9w]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Arahy Arahy~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M9W OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4M9W FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4m9w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arachis_hypogaea Arachis hypogaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M9W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M9W FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4m9b\|4m9b]], [[4map\|4map]], [[4ma6\|4ma6]]~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m9w OCA], [https://pdbe.org/4m9w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m9w RCSB], [https://www.ebi.ac.uk/pdbsum/4m9w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m9w ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4m9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m9w OCA], [~~http~~://pdbe.org/4m9w PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4m9w RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4m9w PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4m9w ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q6VT83_ARAHY Q6VT83_ARAHY]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arahy~~]]	+	[[Category: Arachis hypogaea]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Chruszcz, M]]	+	[[Category: Chruszcz M]]
-	[[Category: Hurlburt~~, B K~~]]	+	[[Category: Hurlburt BK]]
-	[[Category: Majorek~~, K A~~]]	+	[[Category: Majorek KA]]
-	[[Category: Maleki~~, S J~~]]	+	[[Category: Maleki SJ]]
-	[[Category: McBride~~, J K~~]]	+	[[Category: McBride JK]]
-	[[Category: Offermann~~, L R]]~~	+	[[Category: Offermann LR]]
-	~~[[Category: Bet v 1 like]]~~	+
-	~~[[Category: Plant protein]]~~	+
-	~~[[Category: Small molecule carrier~~]]	+

OCA at 09:07, 3 April 2019

OCA — Wed, 03 Apr 2019 09:07:34 GMT

←Older revision		Revision as of 09:07, 3 April 2019
Line 1:		Line 1:

	==Crystal Structure of Ara h 8 with MES bound==		==Crystal Structure of Ara h 8 with MES bound==
-	<StructureSection load='4m9w' size='340' side='right' caption='[[4m9w]], [[Resolution\|resolution]] 1.95Å' scene=''>	+	<StructureSection load='4m9w' size='340' side='right'caption='[[4m9w]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4m9w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arahy Arahy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M9W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M9W FirstGlance]. <br>		<table><tr><td colspan='2'>[[4m9w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arahy Arahy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M9W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M9W FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Arahy]]		[[Category: Arahy]]
		+	[[Category: Large Structures]]
	[[Category: Chruszcz, M]]		[[Category: Chruszcz, M]]
	[[Category: Hurlburt, B K]]		[[Category: Hurlburt, B K]]

OCA at 10:13, 11 August 2016

OCA — Thu, 11 Aug 2016 10:13:39 GMT

←Older revision		Revision as of 10:13, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal Structure of Ara h 8 with MES bound==		==Crystal Structure of Ara h 8 with MES bound==
	<StructureSection load='4m9w' size='340' side='right' caption='[[4m9w]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='4m9w' size='340' side='right' caption='[[4m9w]], [[Resolution\|resolution]] 1.95Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4m9b\|4m9b]], [[4map\|4map]], [[4ma6\|4ma6]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4m9b\|4m9b]], [[4map\|4map]], [[4ma6\|4ma6]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m9w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m9w RCSB], [http://www.ebi.ac.uk/pdbsum/4m9w PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m9w OCA], [http://pdbe.org/4m9w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4m9w RCSB], [http://www.ebi.ac.uk/pdbsum/4m9w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4m9w ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4m9w" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:29, 5 January 2015

OCA — Mon, 05 Jan 2015 09:29:47 GMT

←Older revision		Revision as of 09:29, 5 January 2015
Line 1:		Line 1:
-	~~{{STRUCTURE_4m9w\| PDB=4m9w \| SCENE= }}~~	+	==Crystal Structure of Ara h 8 with MES bound==
-	===Crystal Structure of Ara h 8 with MES bound===	+	<StructureSection load='4m9w' size='340' side='right' caption='[[4m9w]], [[Resolution\|resolution]] 1.95Å' scene=''>
-	~~{{ABSTRACT_PUBMED_24253038}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4m9w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arahy Arahy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M9W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M9W FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4m9b\|4m9b]], [[4map\|4map]], [[4ma6\|4ma6]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m9w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m9w RCSB], [http://www.ebi.ac.uk/pdbsum/4m9w PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The incidence of peanut allergy continues to rise in the United States and Europe. Whereas exposure to the major allergens Ara h 1, 2, 3, and 6 can cause fatal anaphylaxis, exposure to the minor allergens usually does not. Ara h 8 is a minor allergen. Importantly, it is the minor food allergens that are thought to be responsible for oral allergy syndrome (OAS), in which sensitization to airborne allergens causes a Type 2 allergic reaction to ingested foods. Furthermore, it is believed that similar protein structure rather than a similar linear sequence is the cause of OAS. Bet v 1 from birch pollen is a common sensitizing agent, and OAS results when patients consume certain fruits, vegetables, tree nuts, and peanuts. Here, we report the three-dimensional structure of Ara h 8, a Bet v 1 homolog. The overall fold is very similar to that of Bet v 1, Api g 1 (celery), Gly m 4 (soy), and Pru av 1 (cherry). Ara h 8 binds the isoflavones quercetin and apigenin as well as resveratrol avidly.

-	~~==About this~~ Structure==	+	Structure and Function of the Peanut Panallergen Ara h 8.,Hurlburt BK, Offermann LR, McBride JK, Majorek KA, Maleki SJ, Chruszcz M J Biol Chem. 2013 Dec 27;288(52):36890-901. doi: 10.1074/jbc.M113.517797. Epub, 2013 Nov 19. PMID:24253038<ref>PMID:24253038</ref>
-	~~[[4m9w]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Arahy Arahy]~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=4M9W OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:024253038</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Arahy]]		[[Category: Arahy]]
-	[[Category: Chruszcz, M.]]	+	[[Category: Chruszcz, M]]
-	[[Category: Hurlburt, B K.]]	+	[[Category: Hurlburt, B K]]
-	[[Category: Majorek, K A.]]	+	[[Category: Majorek, K A]]
-	[[Category: Maleki, S J.]]	+	[[Category: Maleki, S J]]
-	[[Category: McBride, J K.]]	+	[[Category: McBride, J K]]
-	[[Category: Offermann, L R.]]	+	[[Category: Offermann, L R]]
	[[Category: Bet v 1 like]]		[[Category: Bet v 1 like]]
	[[Category: Plant protein]]		[[Category: Plant protein]]
	[[Category: Small molecule carrier]]		[[Category: Small molecule carrier]]

OCA at 07:15, 15 January 2014

OCA — Wed, 15 Jan 2014 07:15:07 GMT

←Older revision		Revision as of 07:15, 15 January 2014
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	{{STRUCTURE_4m9w\| PDB=4m9w \| SCENE= }}		{{STRUCTURE_4m9w\| PDB=4m9w \| SCENE= }}
	===Crystal Structure of Ara h 8 with MES bound===		===Crystal Structure of Ara h 8 with MES bound===
		+	{{ABSTRACT_PUBMED_24253038}}

	==About this Structure==		==About this Structure==
-	[[4m9w]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M9W OCA].	+	[[4m9w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arahy Arahy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M9W OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:024253038</ref><references group="xtra"/><references/>
		+	[[Category: Arahy]]
	[[Category: Chruszcz, M.]]		[[Category: Chruszcz, M.]]
	[[Category: Hurlburt, B K.]]		[[Category: Hurlburt, B K.]]

OCA at 10:34, 27 November 2013

OCA — Wed, 27 Nov 2013 10:34:51 GMT

←Older revision		Revision as of 10:34, 27 November 2013
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-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4m9w\| PDB=4m9w \| SCENE= }}
		+	===Crystal Structure of Ara h 8 with MES bound===

-	~~The entry~~ 4m9w is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
-		+	[[4m9w]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M9W OCA].
-	~~Authors~~: ~~Offermann, L~~.R., Hurlburt, B.K., Majorek, K.A., McBride, J.K., ~~Maleki, S.J., Chruszcz, M~~.	+	[[Category: Chruszcz, M.]]
-		+	[[Category: Hurlburt, B K.]]
-	~~Description~~: ~~Crystal Structure of Ara h 8 with MES bound~~	+	[[Category: Majorek, K A.]]
		+	[[Category: Maleki, S J.]]
		+	[[Category: McBride, J K.]]
		+	[[Category: Offermann, L R.]]
		+	[[Category: Bet v 1 like]]
		+	[[Category: Plant protein]]
		+	[[Category: Small molecule carrier]]

OCA at 03:36, 20 September 2013

OCA — Fri, 20 Sep 2013 03:36:19 GMT

←Older revision		Revision as of 03:36, 20 September 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4m9w is ON HOLD	+	The entry 4m9w is ON HOLD until Paper Publication

	Authors: Offermann, L.R., Hurlburt, B.K., Majorek, K.A., McBride, J.K., Maleki, S.J., Chruszcz, M.		Authors: Offermann, L.R., Hurlburt, B.K., Majorek, K.A., McBride, J.K., Maleki, S.J., Chruszcz, M.

	Description: Crystal Structure of Ara h 8 with MES bound		Description: Crystal Structure of Ara h 8 with MES bound

OCA: Protected "4m9w" [edit=sysop:move=sysop]

OCA — Wed, 21 Aug 2013 08:00:28 GMT

Protected "4m9w" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:00, 21 August 2013

OCA: New page: '''Unreleased structure''' The entry 4m9w is ON HOLD Authors: Offermann, L.R., Hurlburt, B.K., Majorek, K.A., McBride, J.K., Maleki, S.J., Chruszcz, M. Description: Crystal Structure o...

OCA — Wed, 21 Aug 2013 08:00:27 GMT

New page: '''Unreleased structure''' The entry 4m9w is ON HOLD Authors: Offermann, L.R., Hurlburt, B.K., Majorek, K.A., McBride, J.K., Maleki, S.J., Chruszcz, M. Description: Crystal Structure o...

New page

'''Unreleased structure'''

The entry 4m9w is ON HOLD

Authors: Offermann, L.R., Hurlburt, B.K., Majorek, K.A., McBride, J.K., Maleki, S.J., Chruszcz, M.

Description: Crystal Structure of Ara h 8 with MES bound