4mso - Revision history

OCA at 16:41, 20 September 2023

OCA — Wed, 20 Sep 2023 16:41:47 GMT

←Older revision		Revision as of 16:41, 20 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4mso]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_cenocepacia_J2315 Burkholderia cenocepacia J2315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MSO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MSO FirstGlance]. <br>		<table><tr><td colspan='2'>[[4mso]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_cenocepacia_J2315 Burkholderia cenocepacia J2315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MSO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MSO FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.4Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mso OCA], [https://pdbe.org/4mso PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mso RCSB], [https://www.ebi.ac.uk/pdbsum/4mso PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mso ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mso OCA], [https://pdbe.org/4mso PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mso RCSB], [https://www.ebi.ac.uk/pdbsum/4mso PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mso ProSAT]</span></td></tr>
	</table>		</table>

OCA at 10:05, 28 December 2022

OCA — Wed, 28 Dec 2022 10:05:40 GMT

←Older revision		Revision as of 10:05, 28 December 2022
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	==X-ray crystal structure of a serine hydroxymethyl transferase in apo form from Burkholderia cenocepacia==		==X-ray crystal structure of a serine hydroxymethyl transferase in apo form from Burkholderia cenocepacia==
-	<StructureSection load='4mso' size='340' side='right' caption='[[4mso]], [[Resolution\|resolution]] 1.40Å' scene=''>	+	<StructureSection load='4mso' size='340' side='right'caption='[[4mso]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4mso]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Burcj Burcj~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MSO OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4MSO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4mso]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_cenocepacia_J2315 Burkholderia cenocepacia J2315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MSO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MSO FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glyA, glyA1, BceJ2315_31420, BCAL3197 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=216591 BURCJ])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mso OCA], [https://pdbe.org/4mso PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mso RCSB], [https://www.ebi.ac.uk/pdbsum/4mso PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mso ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycine_hydroxymethyltransferase Glycine hydroxymethyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.2.1 2.1.2.1] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4mso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mso OCA], [~~http~~://pdbe.org/4mso PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4mso RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4mso PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4mso ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/B4ECY9_BURCJ B4ECY9_BURCJ]] Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity).[HAMAP-Rule:MF_00051]	+	[https://www.uniprot.org/uniprot/B4ECY9_BURCJ B4ECY9_BURCJ] Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity).[HAMAP-Rule:MF_00051]

	==See Also==		==See Also==
-	*[[Serine hydroxymethyltransferase\|Serine hydroxymethyltransferase]]	+	*[[Serine hydroxymethyltransferase 3D structures\|Serine hydroxymethyltransferase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Burcj~~]]	+	[[Category: Burkholderia cenocepacia J2315]]
-	[[Category: ~~Glycine hydroxymethyltransferase]]~~	+	[[Category: Large Structures]]
-	~~[[Category: Structural genomic]]~~	+
-	~~[[Category: National institute of allergy and infectious disease]]~~	+
-	~~[[Category: Niaid]]~~	+
-	~~[[Category: Pyridoxal phosphate]]~~	+
-	~~[[Category: Serine hydroxymethyl transferase]]~~	+
-	~~[[Category: Ssgcid]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 05:25, 5 August 2016

OCA — Fri, 05 Aug 2016 05:25:29 GMT

←Older revision		Revision as of 05:25, 5 August 2016
Line 1:		Line 1:
		+
	==X-ray crystal structure of a serine hydroxymethyl transferase in apo form from Burkholderia cenocepacia==		==X-ray crystal structure of a serine hydroxymethyl transferase in apo form from Burkholderia cenocepacia==
	<StructureSection load='4mso' size='340' side='right' caption='[[4mso]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='4mso' size='340' side='right' caption='[[4mso]], [[Resolution\|resolution]] 1.40Å' scene=''>
Line 6:		Line 7:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glyA, glyA1, BceJ2315_31420, BCAL3197 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=216591 BURCJ])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glyA, glyA1, BceJ2315_31420, BCAL3197 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=216591 BURCJ])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycine_hydroxymethyltransferase Glycine hydroxymethyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.2.1 2.1.2.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycine_hydroxymethyltransferase Glycine hydroxymethyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.2.1 2.1.2.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mso OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mso RCSB], [http://www.ebi.ac.uk/pdbsum/4mso PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mso OCA], [http://pdbe.org/4mso PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mso RCSB], [http://www.ebi.ac.uk/pdbsum/4mso PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mso ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 16:07, 25 December 2014

OCA — Thu, 25 Dec 2014 16:07:07 GMT

←Older revision		Revision as of 16:07, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mso OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mso RCSB], [http://www.ebi.ac.uk/pdbsum/4mso PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mso OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mso RCSB], [http://www.ebi.ac.uk/pdbsum/4mso PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/B4ECY9_BURCJ B4ECY9_BURCJ]] Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity).[HAMAP-Rule:MF_00051]

	==See Also==		==See Also==

OCA at 16:23, 21 December 2014

OCA — Sun, 21 Dec 2014 16:23:49 GMT

←Older revision		Revision as of 16:23, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4mso\| PDB=4mso \| SCENE= }}~~	+	==X-ray crystal structure of a serine hydroxymethyl transferase in apo form from Burkholderia cenocepacia==
-	===X-ray crystal structure of a serine hydroxymethyl transferase in apo form from Burkholderia cenocepacia===	+	<StructureSection load='4mso' size='340' side='right' caption='[[4mso]], [[Resolution\|resolution]] 1.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4mso]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Burcj Burcj]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MSO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MSO FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glyA, glyA1, BceJ2315_31420, BCAL3197 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=216591 BURCJ])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycine_hydroxymethyltransferase Glycine hydroxymethyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.2.1 2.1.2.1] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mso OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mso RCSB], [http://www.ebi.ac.uk/pdbsum/4mso PDBsum]</span></td></tr>
		+	</table>

-	==~~Function~~==	+	==See Also==
-	[[~~http://www.uniprot.org/uniprot/B4ECY9_BURCJ B4ECY9_BURCJ~~]] Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity).[HAMAP-Rule:MF_00051]	+	*[[Serine hydroxymethyltransferase\|Serine hydroxymethyltransferase]]
-		+	__TOC__
-	~~==About this Structure==~~	+	</StructureSection>
-	[[~~4mso~~]] ~~is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MSO OCA].~~	+	[[Category: Burcj]]
	[[Category: Glycine hydroxymethyltransferase]]		[[Category: Glycine hydroxymethyltransferase]]
-	[[Category: ~~SSGCID, Seattle~~ Structural ~~Genomics Center for Infectious Disease.~~]]	+	[[Category: Structural genomic]]
	[[Category: National institute of allergy and infectious disease]]		[[Category: National institute of allergy and infectious disease]]
	[[Category: Niaid]]		[[Category: Niaid]]
	[[Category: Pyridoxal phosphate]]		[[Category: Pyridoxal phosphate]]
-	[[Category: Seattle structural genomics center for infectious disease]]
	[[Category: Serine hydroxymethyl transferase]]		[[Category: Serine hydroxymethyl transferase]]
	[[Category: Ssgcid]]		[[Category: Ssgcid]]
-	[[Category: Structural genomic]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 13:52, 11 December 2013

OCA — Wed, 11 Dec 2013 13:52:23 GMT

←Older revision		Revision as of 13:52, 11 December 2013
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_4mso\| PDB=4mso \| SCENE= }}
		+	===X-ray crystal structure of a serine hydroxymethyl transferase in apo form from Burkholderia cenocepacia===

-	~~The entry 4mso is ON HOLD~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/B4ECY9_BURCJ B4ECY9_BURCJ]] Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity).[HAMAP-Rule:MF_00051]

-	~~Authors~~: Seattle Structural Genomics Center for Infectious Disease ~~(SSGCID)~~	+	==About this Structure==
-		+	[[4mso]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MSO OCA].
-	~~Description~~: ~~X-ray crystal structure~~ of ~~a serine~~ hydroxymethyl transferase ~~in apo form from Burkholderia cenocepacia~~	+	[[Category: Glycine hydroxymethyltransferase]]
		+	[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]]
		+	[[Category: National institute of allergy and infectious disease]]
		+	[[Category: Niaid]]
		+	[[Category: Pyridoxal phosphate]]
		+	[[Category: Seattle structural genomics center for infectious disease]]
		+	[[Category: Serine hydroxymethyl transferase]]
		+	[[Category: Ssgcid]]
		+	[[Category: Structural genomic]]
		+	[[Category: Transferase]]

OCA: Protected "4mso" [edit=sysop:move=sysop]

OCA — Sun, 29 Sep 2013 07:44:03 GMT

Protected "4mso" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:44, 29 September 2013

OCA: New page: '''Unreleased structure''' The entry 4mso is ON HOLD Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Description: X-ray crystal structure of a serine hydrox...

OCA — Sun, 29 Sep 2013 07:44:02 GMT

New page: '''Unreleased structure''' The entry 4mso is ON HOLD Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Description: X-ray crystal structure of a serine hydrox...

New page

'''Unreleased structure'''

The entry 4mso is ON HOLD

Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Description: X-ray crystal structure of a serine hydroxymethyl transferase in apo form from Burkholderia cenocepacia