4mvj - Revision history

OCA at 16:43, 20 September 2023

OCA — Wed, 20 Sep 2023 16:43:20 GMT

←Older revision		Revision as of 16:43, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4mvj]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_DH1 Escherichia coli DH1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MVJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MVJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[4mvj]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_DH1 Escherichia coli DH1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MVJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MVJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=SCY:S-ACETYL-CYSTEINE'>SCY</scene>, <scene name='pdbligand=UVW:ACETYLPHOSPHATE'>UVW</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.85Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=SCY:S-ACETYL-CYSTEINE'>SCY</scene>, <scene name='pdbligand=UVW:ACETYLPHOSPHATE'>UVW</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mvj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mvj OCA], [https://pdbe.org/4mvj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mvj RCSB], [https://www.ebi.ac.uk/pdbsum/4mvj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mvj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mvj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mvj OCA], [https://pdbe.org/4mvj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mvj RCSB], [https://www.ebi.ac.uk/pdbsum/4mvj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mvj ProSAT]</span></td></tr>
	</table>		</table>

OCA at 10:12, 28 December 2022

OCA — Wed, 28 Dec 2022 10:12:35 GMT

←Older revision		Revision as of 10:12, 28 December 2022
Line 1:		Line 1:
-	~~{{Large structure}}~~	+
	==2.85 Angstrom Resolution Crystal Structure of Glyceraldehyde 3-phosphate Dehydrogenase A (gapA) from Escherichia coli Modified by Acetyl Phosphate.==		==2.85 Angstrom Resolution Crystal Structure of Glyceraldehyde 3-phosphate Dehydrogenase A (gapA) from Escherichia coli Modified by Acetyl Phosphate.==
-	<StructureSection load='4mvj' size='340' side='right' caption='[[4mvj]], [[Resolution\|resolution]] 2.85Å' scene=''>	+	<StructureSection load='4mvj' size='340' side='right'caption='[[4mvj]], [[Resolution\|resolution]] 2.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4mvj]] is a 16 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Ecod1 Ecod1~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MVJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4MVJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4mvj]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_DH1 Escherichia coli DH1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MVJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MVJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP~~</scene>, <scene name='pdbligand=UVW:ACETYLPHOSPHATE'>UVW</scene></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=SCY:S-ACETYL-CYSTEINE'>SCY</scene>, <scene name='pdbligand=UVW:ACETYLPHOSPHATE'>UVW</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY~~</scene>, <scene name='pdbligand=SCY:S-ACETYL-CYSTEINE'>SCY</scene>~~</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mvj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mvj OCA], [https://pdbe.org/4mvj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mvj RCSB], [https://www.ebi.ac.uk/pdbsum/4mvj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mvj ProSAT]</span></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1s7c\|1s7c]]</td></tr>~~	+
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ECDH1ME8569_1723~~, ~~EcDH1_1863, gapA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=536056 ECOD1])~~<~~/td></tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>[http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.12 1.2.1.12] </~~span~~></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4mvj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mvj OCA], [~~http~~://pdbe.org/4mvj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4mvj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4mvj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4mvj ProSAT]</span></td></tr>	+
	</table>		</table>
-	{{Large structure}}
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 16:
	</div>		</div>
	<div class="pdbe-citations 4mvj" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4mvj" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Glyceraldehyde-3-phosphate dehydrogenase 3D structures\|Glyceraldehyde-3-phosphate dehydrogenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ecod1~~]]	+	[[Category: Escherichia coli DH1]]
-	[[Category: ~~Anderson, W F~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Structural genomic~~]]	+	[[Category: Anderson WF]]
-	[[Category: Dubrovska, I]]	+	[[Category: Dubrovska I]]
-	[[Category: Grimshaw, S]]	+	[[Category: Grimshaw S]]
-	[[Category: Kuhn, M]]	+	[[Category: Kuhn M]]
-	[[Category: Kwon, K]]	+	[[Category: Kwon K]]
-	[[Category: Minasov, G]]	+	[[Category: Minasov G]]
-	[[Category: Shuvalova, L]]	+	[[Category: Shuvalova L]]
-	[[Category: Winsor, J]]	+	[[Category: Winsor J]]
-	~~[[Category: Csgid]]~~	+
-	~~[[Category: N-terminal nad binding domain]]~~	+
-	~~[[Category: National institute of allergy and infectious disease]]~~	+
-	~~[[Category: Niaid]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 14:42, 11 August 2016

OCA — Thu, 11 Aug 2016 14:42:49 GMT

←Older revision		Revision as of 14:42, 11 August 2016
Line 1:		Line 1:
		+	{{Large structure}}
	==2.85 Angstrom Resolution Crystal Structure of Glyceraldehyde 3-phosphate Dehydrogenase A (gapA) from Escherichia coli Modified by Acetyl Phosphate.==		==2.85 Angstrom Resolution Crystal Structure of Glyceraldehyde 3-phosphate Dehydrogenase A (gapA) from Escherichia coli Modified by Acetyl Phosphate.==
	<StructureSection load='4mvj' size='340' side='right' caption='[[4mvj]], [[Resolution\|resolution]] 2.85Å' scene=''>		<StructureSection load='4mvj' size='340' side='right' caption='[[4mvj]], [[Resolution\|resolution]] 2.85Å' scene=''>
Line 8:		Line 9:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ECDH1ME8569_1723, EcDH1_1863, gapA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=536056 ECOD1])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ECDH1ME8569_1723, EcDH1_1863, gapA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=536056 ECOD1])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.12 1.2.1.12] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.12 1.2.1.12] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mvj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mvj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mvj RCSB], [http://www.ebi.ac.uk/pdbsum/4mvj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mvj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mvj OCA], [http://pdbe.org/4mvj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mvj RCSB], [http://www.ebi.ac.uk/pdbsum/4mvj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mvj ProSAT]</span></td></tr>
	</table>		</table>
		+	{{Large structure}}
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4mvj" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:58, 5 January 2015

OCA — Mon, 05 Jan 2015 08:58:23 GMT

←Older revision		Revision as of 08:58, 5 January 2015
Line 2:		Line 2:
	<StructureSection load='4mvj' size='340' side='right' caption='[[4mvj]], [[Resolution\|resolution]] 2.85Å' scene=''>		<StructureSection load='4mvj' size='340' side='right' caption='[[4mvj]], [[Resolution\|resolution]] 2.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4mvj]] is a 16 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MVJ OCA]. <br>	+	<table><tr><td colspan='2'>[[4mvj]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecod1 Ecod1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MVJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MVJ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=UVW:ACETYLPHOSPHATE'>UVW</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=UVW:ACETYLPHOSPHATE'>UVW</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=SCY:S-ACETYL-CYSTEINE'>SCY</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=SCY:S-ACETYL-CYSTEINE'>SCY</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1s7c\|1s7c]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1s7c\|1s7c]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/~~Glucokinase Glucokinase~~], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 ~~2.7~~.1.2] </span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ECDH1ME8569_1723, EcDH1_1863, gapA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=536056 ECOD1])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mvj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mvj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mvj RCSB], [http://www.ebi.ac.uk/pdbsum/4mvj PDBsum]</span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.12 1.2.1.12] </span></td></tr>
-	<table>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mvj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mvj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mvj RCSB], [http://www.ebi.ac.uk/pdbsum/4mvj PDBsum]</span></td></tr>
		+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 15:		Line 16:
	Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation.,Kuhn ML, Zemaitaitis B, Hu LI, Sahu A, Sorensen D, Minasov G, Lima BP, Scholle M, Mrksich M, Anderson WF, Gibson BW, Schilling B, Wolfe AJ PLoS One. 2014 Apr 22;9(4):e94816. doi: 10.1371/journal.pone.0094816. eCollection, 2014. PMID:24756028<ref>PMID:24756028</ref>		Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation.,Kuhn ML, Zemaitaitis B, Hu LI, Sahu A, Sorensen D, Minasov G, Lima BP, Scholle M, Mrksich M, Anderson WF, Gibson BW, Schilling B, Wolfe AJ PLoS One. 2014 Apr 22;9(4):e94816. doi: 10.1371/journal.pone.0094816. eCollection, 2014. PMID:24756028<ref>PMID:24756028</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 21:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Anderson, W F.]]	+	[[Category: Ecod1]]
-	[[Category: ~~CSGID, Center for~~ Structural ~~Genomics of Infectious Diseases.~~]]	+	[[Category: Anderson, W F]]
-	[[Category: Dubrovska, I.]]	+	[[Category: Structural genomic]]
-	[[Category: Grimshaw, S.]]	+	[[Category: Dubrovska, I]]
-	[[Category: Kuhn, M.]]	+	[[Category: Grimshaw, S]]
-	[[Category: Kwon, K.]]	+	[[Category: Kuhn, M]]
-	[[Category: Minasov, G.]]	+	[[Category: Kwon, K]]
-	[[Category: Shuvalova, L.]]	+	[[Category: Minasov, G]]
-	[[Category: Winsor, J~~.]]~~	+	[[Category: Shuvalova, L]]
-	~~[[Category: Center for structural genomics of infectious disease~~]]	+	[[Category: Winsor, J]]
	[[Category: Csgid]]		[[Category: Csgid]]
	[[Category: N-terminal nad binding domain]]		[[Category: N-terminal nad binding domain]]
Line 36:		Line 37:
	[[Category: Niaid]]		[[Category: Niaid]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
-	[[Category: Structural genomic]]

OCA at 06:59, 7 May 2014

OCA — Wed, 07 May 2014 06:59:52 GMT

←Older revision		Revision as of 06:59, 7 May 2014
Line 1:		Line 1:
-	~~{{Large structure}}~~	+	==2.85 Angstrom Resolution Crystal Structure of Glyceraldehyde 3-phosphate Dehydrogenase A (gapA) from Escherichia coli Modified by Acetyl Phosphate.==
-	~~{{STRUCTURE_4mvj\| PDB=4mvj \| SCENE= }}~~	+	<StructureSection load='4mvj' size='340' side='right' caption='[[4mvj]], [[Resolution\|resolution]] 2.85Å' scene=''>
-	===2.85 Angstrom Resolution Crystal Structure of Glyceraldehyde 3-phosphate Dehydrogenase A (gapA) from Escherichia coli Modified by Acetyl Phosphate.===	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4mvj]] is a 16 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MVJ OCA]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=UVW:ACETYLPHOSPHATE'>UVW</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=SCY:S-ACETYL-CYSTEINE'>SCY</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1s7c\|1s7c]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mvj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mvj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mvj RCSB], [http://www.ebi.ac.uk/pdbsum/4mvj PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The emerging view of Nepsilon-lysine acetylation in eukaryotes is of a relatively abundant post-translational modification (PTM) that has a major impact on the function, structure, stability and/or location of thousands of proteins involved in diverse cellular processes. This PTM is typically considered to arise by the donation of the acetyl group from acetyl-coenzyme A (acCoA) to the epsilon-amino group of a lysine residue that is reversibly catalyzed by lysine acetyltransferases and deacetylases. Here, we provide genetic, mass spectrometric, biochemical and structural evidence that Nepsilon-lysine acetylation is an equally abundant and important PTM in bacteria. Applying a recently developed, label-free and global mass spectrometric approach to an isogenic set of mutants, we detected acetylation of thousands of lysine residues on hundreds of Escherichia coli proteins that participate in diverse and often essential cellular processes, including translation, transcription and central metabolism. Many of these acetylations were regulated in an acetyl phosphate (acP)-dependent manner, providing compelling evidence for a recently reported mechanism of bacterial Nepsilon-lysine acetylation. These mass spectrometric data, coupled with observations made by crystallography, biochemistry, and additional mass spectrometry showed that this acP-dependent acetylation is both non-enzymatic and specific, with specificity determined by the accessibility, reactivity and three-dimensional microenvironment of the target lysine. Crystallographic evidence shows acP can bind to proteins in active sites and cofactor binding sites, but also potentially anywhere molecules with a phosphate moiety could bind. Finally, we provide evidence that acP-dependent acetylation can impact the function of critical enzymes, including glyceraldehyde-3-phosphate dehydrogenase, triosephosphate isomerase, and RNA polymerase.

-	~~==About this Structure==~~	+	Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation.,Kuhn ML, Zemaitaitis B, Hu LI, Sahu A, Sorensen D, Minasov G, Lima BP, Scholle M, Mrksich M, Anderson WF, Gibson BW, Schilling B, Wolfe AJ PLoS One. 2014 Apr 22;9(4):e94816. doi: 10.1371/journal.pone.0094816. eCollection, 2014. PMID:24756028<ref>PMID:24756028</ref>
-	~~[[4mvj]] is a 16 chain structure~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.ac.il/~~oca-bin~~/~~ocashort?id=4MVJ OCA]~~.	+
		+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Anderson, W F.]]		[[Category: Anderson, W F.]]
	[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]		[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]

OCA at 07:56, 23 April 2014

OCA — Wed, 23 Apr 2014 07:56:05 GMT

←Older revision		Revision as of 07:56, 23 April 2014
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	{{Large structure}}
		+	{{STRUCTURE_4mvj\| PDB=4mvj \| SCENE= }}
		+	===2.85 Angstrom Resolution Crystal Structure of Glyceraldehyde 3-phosphate Dehydrogenase A (gapA) from Escherichia coli Modified by Acetyl Phosphate.===

-	~~The entry~~ 4mvj is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
-		+	[[4mvj]] is a 16 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MVJ OCA].
-	~~Authors~~: ~~Minasov~~, G., ~~Kuhn, M~~., Dubrovska, I.~~, Winsor, J., Shuvalova, L.,~~ Grimshaw, S., Kwon, K., ~~Anderson~~, ~~W.F~~., Center for ~~Structural Genomics~~ of ~~Infectious Diseases (CSGID)~~	+	[[Category: Anderson, W F.]]
-		+	[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
-	~~Description~~: ~~2.85 Angstrom Resolution Crystal Structure of Glyceraldehyde 3~~-~~phosphate Dehydrogenase A (gapA) from Escherichia coli Modified by Acetyl Phosphate.~~	+	[[Category: Dubrovska, I.]]
		+	[[Category: Grimshaw, S.]]
		+	[[Category: Kuhn, M.]]
		+	[[Category: Kwon, K.]]
		+	[[Category: Minasov, G.]]
		+	[[Category: Shuvalova, L.]]
		+	[[Category: Winsor, J.]]
		+	[[Category: Center for structural genomics of infectious disease]]
		+	[[Category: Csgid]]
		+	[[Category: N-terminal nad binding domain]]
		+	[[Category: National institute of allergy and infectious disease]]
		+	[[Category: Niaid]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Structural genomic]]

OCA at 06:59, 6 November 2013

OCA — Wed, 06 Nov 2013 06:59:26 GMT

←Older revision		Revision as of 06:59, 6 November 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4mvj is ON HOLD	+	The entry 4mvj is ON HOLD until Paper Publication

	Authors: Minasov, G., Kuhn, M., Dubrovska, I., Winsor, J., Shuvalova, L., Grimshaw, S., Kwon, K., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)		Authors: Minasov, G., Kuhn, M., Dubrovska, I., Winsor, J., Shuvalova, L., Grimshaw, S., Kwon, K., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

	Description: 2.85 Angstrom Resolution Crystal Structure of Glyceraldehyde 3-phosphate Dehydrogenase A (gapA) from Escherichia coli Modified by Acetyl Phosphate.		Description: 2.85 Angstrom Resolution Crystal Structure of Glyceraldehyde 3-phosphate Dehydrogenase A (gapA) from Escherichia coli Modified by Acetyl Phosphate.

OCA at 07:28, 16 October 2013

OCA — Wed, 16 Oct 2013 07:28:18 GMT

←Older revision		Revision as of 07:28, 16 October 2013
Line 3:		Line 3:
	The entry 4mvj is ON HOLD		The entry 4mvj is ON HOLD

-	Authors: Minasov, G., Kuhn, M., Dubrovska, I., Winsor, J., Shuvalova, L., Grimshaw, S. , Kwon, K. , Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)	+	Authors: Minasov, G., Kuhn, M., Dubrovska, I., Winsor, J., Shuvalova, L., Grimshaw, S., Kwon, K., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

	Description: 2.85 Angstrom Resolution Crystal Structure of Glyceraldehyde 3-phosphate Dehydrogenase A (gapA) from Escherichia coli Modified by Acetyl Phosphate.		Description: 2.85 Angstrom Resolution Crystal Structure of Glyceraldehyde 3-phosphate Dehydrogenase A (gapA) from Escherichia coli Modified by Acetyl Phosphate.

OCA: Protected "4mvj" [edit=sysop:move=sysop]

OCA — Wed, 02 Oct 2013 06:56:05 GMT

Protected "4mvj" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:56, 2 October 2013

OCA: New page: '''Unreleased structure''' The entry 4mvj is ON HOLD Authors: Minasov, G., Kuhn, M., Dubrovska, I., Winsor, J., Shuvalova, L., Grimshaw, S. , Kwon, K. , Anderson, W.F., Center for Struc...

OCA — Wed, 02 Oct 2013 06:56:04 GMT

New page: '''Unreleased structure''' The entry 4mvj is ON HOLD Authors: Minasov, G., Kuhn, M., Dubrovska, I., Winsor, J., Shuvalova, L., Grimshaw, S. , Kwon, K. , Anderson, W.F., Center for Struc...

New page

'''Unreleased structure'''

The entry 4mvj is ON HOLD

Authors: Minasov, G., Kuhn, M., Dubrovska, I., Winsor, J., Shuvalova, L., Grimshaw, S. , Kwon, K. , Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

Description: 2.85 Angstrom Resolution Crystal Structure of Glyceraldehyde 3-phosphate Dehydrogenase A (gapA) from Escherichia coli Modified by Acetyl Phosphate.