4n1k - Revision history

OCA at 12:30, 1 March 2024

OCA — Fri, 01 Mar 2024 12:30:41 GMT

←Older revision		Revision as of 12:30, 1 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4n1k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N1K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N1K FirstGlance]. <br>		<table><tr><td colspan='2'>[[4n1k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N1K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N1K FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n1k OCA], [https://pdbe.org/4n1k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n1k RCSB], [https://www.ebi.ac.uk/pdbsum/4n1k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n1k ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n1k OCA], [https://pdbe.org/4n1k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n1k RCSB], [https://www.ebi.ac.uk/pdbsum/4n1k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n1k ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/NAL14_HUMAN NAL14_HUMAN] May be involved in inflammation and spermatogenesis.		[https://www.uniprot.org/uniprot/NAL14_HUMAN NAL14_HUMAN] May be involved in inflammation and spermatogenesis.
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The cytosolic tripartite NLR receptors serve as important signalling platforms in innate immunity. While the C-terminal domains act as sensor and activation modules, the N-terminal death-like domain, e.g. the CARD or pyrin domain, is thought to recruit downstream effector molecules by homotypic interactions. Such homotypic complexes have been determined for all members of the death-domain superfamily except for pyrin domains. Here, crystal structures of human NLRP14 pyrin-domain variants are reported. The wild-type protein as well as the clinical D86V mutant reveal an unexpected rearrangement of the C-terminal helix alpha6, resulting in an extended alpha5/6 stem-helix. This reordering mediates a novel symmetric pyrin-domain dimerization mode. The conformational switching is controlled by a charge-relay system with a drastic impact on protein stability. How the identified charge relay allows classification of NLRP receptors with respect to distinct recruitment mechanisms is discussed.
-
-	Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions.,Eibl C, Hessenberger M, Wenger J, Brandstetter H Acta Crystallogr D Biol Crystallogr. 2014 Jul;70(Pt 7):2007-18. doi:, 10.1107/S1399004714010311. Epub 2014 Jun 29. PMID:25004977<ref>PMID:25004977</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4n1k" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Pyrin domain\|Pyrin domain]]		*[[Pyrin domain\|Pyrin domain]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 10:26, 28 December 2022

OCA — Wed, 28 Dec 2022 10:26:32 GMT

←Older revision		Revision as of 10:26, 28 December 2022
Line 1:		Line 1:

	==Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions==		==Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions==
-	<StructureSection load='4n1k' size='340' side='right' caption='[[4n1k]], [[Resolution\|resolution]] 3.00Å' scene=''>	+	<StructureSection load='4n1k' size='340' side='right'caption='[[4n1k]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4n1k]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N1K OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4N1K FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4n1k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N1K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N1K FirstGlance]. <br>
-	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4n1j\|4n1j]], [[4n1l\|4n1l]]</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n1k OCA], [https://pdbe.org/4n1k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n1k RCSB], [https://www.ebi.ac.uk/pdbsum/4n1k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n1k ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NLRP14, NALP14, NOD5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4n1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n1k OCA], [~~http~~://pdbe.org/4n1k PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4n1k RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4n1k PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4n1k ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/NAL14_HUMAN NAL14_HUMAN]] May be involved in inflammation and spermatogenesis.	+	[https://www.uniprot.org/uniprot/NAL14_HUMAN NAL14_HUMAN] May be involved in inflammation and spermatogenesis.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 17:
	</div>		</div>
	<div class="pdbe-citations 4n1k" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4n1k" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Pyrin domain\|Pyrin domain]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: Brandstetter, H]]	+	[[Category: Large Structures]]
-	[[Category: Eibl, C]]	+	[[Category: Brandstetter H]]
-	[[Category: Hessenberger, M]]	+	[[Category: Eibl C]]
-	[[Category: Wenger, J]]	+	[[Category: Hessenberger M]]
-	~~[[Category: Death domain fold]]~~	+	[[Category: Wenger J]]
-	~~[[Category: Innate immunity]]~~	+
-	~~[[Category: Nod-like receptor]]~~	+
-	~~[[Category: Protein binding]]~~	+
-	~~[[Category: Pyrin domain]]~~	+
-	~~[[Category: Signaling protein]]~~	+
-	~~[[Category: Spermatogenesis~~]]	+

OCA at 10:00, 15 November 2017

OCA — Wed, 15 Nov 2017 10:00:24 GMT

←Older revision		Revision as of 10:00, 15 November 2017
Line 3:		Line 3:
	<StructureSection load='4n1k' size='340' side='right' caption='[[4n1k]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='4n1k' size='340' side='right' caption='[[4n1k]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4n1k]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N1K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4N1K FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4n1k]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N1K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4N1K FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4n1j\|4n1j]], [[4n1l\|4n1l]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4n1j\|4n1j]], [[4n1l\|4n1l]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NLRP14, NALP14, NOD5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n1k OCA], [http://pdbe.org/4n1k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4n1k RCSB], [http://www.ebi.ac.uk/pdbsum/4n1k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4n1k ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n1k OCA], [http://pdbe.org/4n1k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4n1k RCSB], [http://www.ebi.ac.uk/pdbsum/4n1k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4n1k ProSAT]</span></td></tr>
	</table>		</table>
Line 22:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Brandstetter, H]]		[[Category: Brandstetter, H]]
	[[Category: Eibl, C]]		[[Category: Eibl, C]]

OCA at 05:51, 5 August 2016

OCA — Fri, 05 Aug 2016 05:51:38 GMT

←Older revision		Revision as of 05:51, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions==		==Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions==
	<StructureSection load='4n1k' size='340' side='right' caption='[[4n1k]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='4n1k' size='340' side='right' caption='[[4n1k]], [[Resolution\|resolution]] 3.00Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4n1k]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N1K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4N1K FirstGlance]. <br>		<table><tr><td colspan='2'>[[4n1k]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N1K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4N1K FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4n1j\|4n1j]], [[4n1l\|4n1l]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4n1j\|4n1j]], [[4n1l\|4n1l]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n1k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4n1k RCSB], [http://www.ebi.ac.uk/pdbsum/4n1k PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n1k OCA], [http://pdbe.org/4n1k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4n1k RCSB], [http://www.ebi.ac.uk/pdbsum/4n1k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4n1k ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4n1k" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 23:33, 24 December 2014

OCA — Wed, 24 Dec 2014 23:33:19 GMT

←Older revision		Revision as of 23:33, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4n1k]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N1K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4N1K FirstGlance]. <br>		<table><tr><td colspan='2'>[[4n1k]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N1K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4N1K FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4n1j\|4n1j]], [[4n1l\|4n1l]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4n1j\|4n1j]], [[4n1l\|4n1l]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n1k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4n1k RCSB], [http://www.ebi.ac.uk/pdbsum/4n1k PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n1k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4n1k RCSB], [http://www.ebi.ac.uk/pdbsum/4n1k PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NAL14_HUMAN NAL14_HUMAN]] May be involved in inflammation and spermatogenesis.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Brandstetter, H.]]	+	[[Category: Brandstetter, H]]
-	[[Category: Eibl, C.]]	+	[[Category: Eibl, C]]
-	[[Category: Hessenberger, M.]]	+	[[Category: Hessenberger, M]]
-	[[Category: Wenger, J.]]	+	[[Category: Wenger, J]]
	[[Category: Death domain fold]]		[[Category: Death domain fold]]
	[[Category: Innate immunity]]		[[Category: Innate immunity]]

OCA at 06:19, 24 September 2014

OCA — Wed, 24 Sep 2014 06:19:27 GMT

←Older revision		Revision as of 06:19, 24 September 2014
Line 6:		Line 6:
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n1k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4n1k RCSB], [http://www.ebi.ac.uk/pdbsum/4n1k PDBsum]</span></td></tr>		<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n1k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4n1k RCSB], [http://www.ebi.ac.uk/pdbsum/4n1k PDBsum]</span></td></tr>
	<table>		<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The cytosolic tripartite NLR receptors serve as important signalling platforms in innate immunity. While the C-terminal domains act as sensor and activation modules, the N-terminal death-like domain, e.g. the CARD or pyrin domain, is thought to recruit downstream effector molecules by homotypic interactions. Such homotypic complexes have been determined for all members of the death-domain superfamily except for pyrin domains. Here, crystal structures of human NLRP14 pyrin-domain variants are reported. The wild-type protein as well as the clinical D86V mutant reveal an unexpected rearrangement of the C-terminal helix alpha6, resulting in an extended alpha5/6 stem-helix. This reordering mediates a novel symmetric pyrin-domain dimerization mode. The conformational switching is controlled by a charge-relay system with a drastic impact on protein stability. How the identified charge relay allows classification of NLRP receptors with respect to distinct recruitment mechanisms is discussed.
		+
		+	Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions.,Eibl C, Hessenberger M, Wenger J, Brandstetter H Acta Crystallogr D Biol Crystallogr. 2014 Jul;70(Pt 7):2007-18. doi:, 10.1107/S1399004714010311. Epub 2014 Jun 29. PMID:25004977<ref>PMID:25004977</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 10:29, 16 July 2014

OCA — Wed, 16 Jul 2014 10:29:05 GMT

←Older revision		Revision as of 10:29, 16 July 2014
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions==
-		+	<StructureSection load='4n1k' size='340' side='right' caption='[[4n1k]], [[Resolution\|resolution]] 3.00Å' scene=''>
-	~~The entry~~ 4n1k is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4n1k]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N1K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4N1K FirstGlance]. <br>
-	~~Authors~~: Eibl, C., Hessenberger, M., Wenger, J.~~, Brandstetter, H.~~	+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4n1j\|4n1j]], [[4n1l\|4n1l]]</td></tr>
-		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n1k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4n1k RCSB], [http://www.ebi.ac.uk/pdbsum/4n1k PDBsum]</span></td></tr>
-	~~Description~~: ~~Crystal structures of NLRP14 pyrin~~ domain ~~reveal a conformational switch mechanism, regulating its molecular interactions~~	+	<table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Brandstetter, H.]]
		+	[[Category: Eibl, C.]]
		+	[[Category: Hessenberger, M.]]
		+	[[Category: Wenger, J.]]
		+	[[Category: Death domain fold]]
		+	[[Category: Innate immunity]]
		+	[[Category: Nod-like receptor]]
		+	[[Category: Protein binding]]
		+	[[Category: Pyrin domain]]
		+	[[Category: Signaling protein]]
		+	[[Category: Spermatogenesis]]

OCA: Protected "4n1k" [edit=sysop:move=sysop]

OCA — Wed, 16 Oct 2013 07:31:11 GMT

Protected "4n1k" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:31, 16 October 2013

OCA: New page: '''Unreleased structure''' The entry 4n1k is ON HOLD until Paper Publication Authors: Eibl, C., Hessenberger, M., Wenger, J., Brandstetter, H. Description: Crystal structures of NLRP14...

OCA — Wed, 16 Oct 2013 07:31:10 GMT

New page: '''Unreleased structure''' The entry 4n1k is ON HOLD until Paper Publication Authors: Eibl, C., Hessenberger, M., Wenger, J., Brandstetter, H. Description: Crystal structures of NLRP14...

New page

'''Unreleased structure'''

The entry 4n1k is ON HOLD until Paper Publication

Authors: Eibl, C., Hessenberger, M., Wenger, J., Brandstetter, H.

Description: Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions