4nem - Revision history

OCA at 08:25, 11 January 2023

OCA — Wed, 11 Jan 2023 08:25:23 GMT

←Older revision		Revision as of 08:25, 11 January 2023
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	<StructureSection load='4nem' size='340' side='right'caption='[[4nem]], [[Resolution\|resolution]] 1.93Å' scene=''>		<StructureSection load='4nem' size='340' side='right'caption='[[4nem]], [[Resolution\|resolution]] 1.93Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4nem]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NEM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4NEM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4nem]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NEM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NEM FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2JY:5-[(2,3-DICHLOROPHENOXY)METHYL]FURAN-2-CARBOXYLIC+ACID'>2JY</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2JY:5-[(2,3-DICHLOROPHENOXY)METHYL]FURAN-2-CARBOXYLIC+ACID'>2JY</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4nej\|4nej]]~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nem OCA], [https://pdbe.org/4nem PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nem RCSB], [https://www.ebi.ac.uk/pdbsum/4nem PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nem ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4nem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nem OCA], [~~http~~://pdbe.org/4nem PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4nem RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4nem PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4nem ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Disease ==
		+	[https://www.uniprot.org/uniprot/IL2_HUMAN IL2_HUMAN] Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/IL2_HUMAN IL2_HUMAN] Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.

	==See Also==		==See Also==
-	*[[Interleukin\|Interleukin]]	+	*[[Interleukin 3D structures\|Interleukin 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Allen~~, K N~~]]	+	[[Category: Allen KN]]
-	[[Category: Brenke, R]]	+	[[Category: Brenke R]]
-	[[Category: Jehle, S]]	+	[[Category: Jehle S]]
-	[[Category: Kozakov, D]]	+	[[Category: Kozakov D]]
-	[[Category: Vajda, S]]	+	[[Category: Vajda S]]
-	~~[[Category: Cd25]]~~	+
-	~~[[Category: Crystal contact]]~~	+
-	~~[[Category: Cytokine]]~~	+
-	~~[[Category: Extracellular]]~~	+
-	~~[[Category: Fragment mapping]]~~	+
-	~~[[Category: Helixbundle]]~~	+
-	~~[[Category: Immune system]]~~	+
-	~~[[Category: Interleukin-2~~]]	+

OCA at 08:07, 10 April 2019

OCA — Wed, 10 Apr 2019 08:07:06 GMT

←Older revision		Revision as of 08:07, 10 April 2019
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	==Small molecular fragment bound to crystal contact interface of Interleukin-2==		==Small molecular fragment bound to crystal contact interface of Interleukin-2==
-	<StructureSection load='4nem' size='340' side='right' caption='[[4nem]], [[Resolution\|resolution]] 1.93Å' scene=''>	+	<StructureSection load='4nem' size='340' side='right'caption='[[4nem]], [[Resolution\|resolution]] 1.93Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4nem]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NEM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NEM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4nem]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NEM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NEM FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2JY:5-[(2,3-DICHLOROPHENOXY)METHYL]FURAN-2-CARBOXYLIC+ACID'>2JY</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2JY:5-[(2,3-DICHLOROPHENOXY)METHYL]FURAN-2-CARBOXYLIC+ACID'>2JY</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4nej\|4nej]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4nej\|4nej]]</td></tr>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Allen, K N]]		[[Category: Allen, K N]]
	[[Category: Brenke, R]]		[[Category: Brenke, R]]

OCA at 13:15, 11 August 2016

OCA — Thu, 11 Aug 2016 13:15:40 GMT

←Older revision		Revision as of 13:15, 11 August 2016
Line 1:		Line 1:
		+
	==Small molecular fragment bound to crystal contact interface of Interleukin-2==		==Small molecular fragment bound to crystal contact interface of Interleukin-2==
	<StructureSection load='4nem' size='340' side='right' caption='[[4nem]], [[Resolution\|resolution]] 1.93Å' scene=''>		<StructureSection load='4nem' size='340' side='right' caption='[[4nem]], [[Resolution\|resolution]] 1.93Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2JY:5-[(2,3-DICHLOROPHENOXY)METHYL]FURAN-2-CARBOXYLIC+ACID'>2JY</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2JY:5-[(2,3-DICHLOROPHENOXY)METHYL]FURAN-2-CARBOXYLIC+ACID'>2JY</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4nej\|4nej]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4nej\|4nej]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nem OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nem RCSB], [http://www.ebi.ac.uk/pdbsum/4nem PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nem OCA], [http://pdbe.org/4nem PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4nem RCSB], [http://www.ebi.ac.uk/pdbsum/4nem PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4nem ProSAT]</span></td></tr>
	</table>		</table>
		+
		+	==See Also==
		+	*[[Interleukin\|Interleukin]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 12:49, 19 November 2014

OCA — Wed, 19 Nov 2014 12:49:16 GMT

←Older revision		Revision as of 12:49, 19 November 2014
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-	'''~~Unreleased structure~~'''	+	==Small molecular fragment bound to crystal contact interface of Interleukin-2==
-		+	<StructureSection load='4nem' size='340' side='right' caption='[[4nem]], [[Resolution\|resolution]] 1.93Å' scene=''>
-	~~The entry~~ 4nem is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4nem]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NEM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NEM FirstGlance]. <br>
-	~~Authors~~: ~~Jehle~~, S., ~~Brenke, R~~., ~~Vajda, S~~., Allen, K.N., Kozakov, D.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2JY:5-[(2,3-DICHLOROPHENOXY)METHYL]FURAN-2-CARBOXYLIC+ACID'>2JY</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4nej\|4nej]]</td></tr>
-	~~Description~~: ~~Small molecular fragment bound to crystal~~ contact ~~interface of~~ Interleukin-2	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nem OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nem RCSB], [http://www.ebi.ac.uk/pdbsum/4nem PDBsum]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Allen, K N]]
		+	[[Category: Brenke, R]]
		+	[[Category: Jehle, S]]
		+	[[Category: Kozakov, D]]
		+	[[Category: Vajda, S]]
		+	[[Category: Cd25]]
		+	[[Category: Crystal contact]]
		+	[[Category: Cytokine]]
		+	[[Category: Extracellular]]
		+	[[Category: Fragment mapping]]
		+	[[Category: Helixbundle]]
		+	[[Category: Immune system]]
		+	[[Category: Interleukin-2]]

OCA at 09:12, 8 January 2014

OCA — Wed, 08 Jan 2014 09:12:31 GMT

←Older revision		Revision as of 09:12, 8 January 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4nem is ON HOLD	+	The entry 4nem is ON HOLD until Paper Publication

	Authors: Jehle, S., Brenke, R., Vajda, S., Allen, K.N., Kozakov, D.		Authors: Jehle, S., Brenke, R., Vajda, S., Allen, K.N., Kozakov, D.

	Description: Small molecular fragment bound to crystal contact interface of Interleukin-2		Description: Small molecular fragment bound to crystal contact interface of Interleukin-2

OCA: Protected "4nem" [edit=sysop:move=sysop]

OCA — Wed, 13 Nov 2013 07:45:38 GMT

Protected "4nem" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:45, 13 November 2013

OCA: New page: '''Unreleased structure''' The entry 4nem is ON HOLD Authors: Jehle, S., Brenke, R., Vajda, S., Allen, K.N., Kozakov, D. Description: Small molecular fragment bound to crystal contact ...

OCA — Wed, 13 Nov 2013 07:45:37 GMT

New page: '''Unreleased structure''' The entry 4nem is ON HOLD Authors: Jehle, S., Brenke, R., Vajda, S., Allen, K.N., Kozakov, D. Description: Small molecular fragment bound to crystal contact ...

New page

'''Unreleased structure'''

The entry 4nem is ON HOLD

Authors: Jehle, S., Brenke, R., Vajda, S., Allen, K.N., Kozakov, D.

Description: Small molecular fragment bound to crystal contact interface of Interleukin-2