4o6i - Revision history

OCA at 17:07, 20 September 2023

OCA — Wed, 20 Sep 2023 17:07:41 GMT

←Older revision		Revision as of 17:07, 20 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4o6i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lymphocytic_choriomeningitis_virus_(strain_Armstrong) Lymphocytic choriomeningitis virus (strain Armstrong)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O6I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O6I FirstGlance]. <br>		<table><tr><td colspan='2'>[[4o6i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lymphocytic_choriomeningitis_virus_(strain_Armstrong) Lymphocytic choriomeningitis virus (strain Armstrong)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O6I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O6I FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o6i OCA], [https://pdbe.org/4o6i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o6i RCSB], [https://www.ebi.ac.uk/pdbsum/4o6i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o6i ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o6i OCA], [https://pdbe.org/4o6i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o6i RCSB], [https://www.ebi.ac.uk/pdbsum/4o6i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o6i ProSAT]</span></td></tr>
	</table>		</table>

OCA at 08:58, 18 January 2023

OCA — Wed, 18 Jan 2023 08:58:07 GMT

←Older revision		Revision as of 08:58, 18 January 2023
Line 3:		Line 3:
	<StructureSection load='4o6i' size='340' side='right'caption='[[4o6i]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4o6i' size='340' side='right'caption='[[4o6i]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4o6i]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Lcmv Lcmv~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O6I OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4O6I FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4o6i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lymphocytic_choriomeningitis_virus_(strain_Armstrong) Lymphocytic choriomeningitis virus (strain Armstrong)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O6I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O6I FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4o6h\|4o6h]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o6i OCA], [https://pdbe.org/4o6i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o6i RCSB], [https://www.ebi.ac.uk/pdbsum/4o6i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o6i ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">N ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11624 LCMV])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4o6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o6i OCA], [~~http~~://pdbe.org/4o6i PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4o6i RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4o6i PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4o6i ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/NCAP_LYCVA NCAP_LYCVA]] Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Disables the host innate defense by interfering with beta interferon (IFNB) production through the inhibition of host IRF3 phosphorylation and activation by host IKBKE. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of IRF3, a protein involved in IFN activation pathway, leading to the inhibition of IFNB and IRF3-dependent promoters activation.<ref>PMID:12610166</ref> <ref>PMID:17804508</ref> <ref>PMID:22532683</ref>	+	[https://www.uniprot.org/uniprot/NCAP_LYCVA NCAP_LYCVA] Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Disables the host innate defense by interfering with beta interferon (IFNB) production through the inhibition of host IRF3 phosphorylation and activation by host IKBKE. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of IRF3, a protein involved in IFN activation pathway, leading to the inhibition of IFNB and IRF3-dependent promoters activation.<ref>PMID:12610166</ref> <ref>PMID:17804508</ref> <ref>PMID:22532683</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 20:

	==See Also==		==See Also==
-	*[[Nucleoprotein\|Nucleoprotein]]	+	*[[Nucleoprotein 3D structures\|Nucleoprotein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 28:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Lcmv]]~~	+	[[Category: Hastie KM]]
-	[[Category: Hastie~~, K M~~]]	+	[[Category: Saphire EO]]
-	[[Category: Saphire~~, E O~~]]	+	[[Category: West BR]]
-	[[Category: West~~, B R]]~~	+
-	~~[[Category: Exoribonuclease]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Ribonucleoprotein~~]]	+

OCA at 09:09, 10 April 2019

OCA — Wed, 10 Apr 2019 09:09:48 GMT

←Older revision		Revision as of 09:09, 10 April 2019
Line 1:		Line 1:

	==2.0A crystal structure of Lymphocytic Choriomeningitis Virus Nucleoprotein C-terminal Domain==		==2.0A crystal structure of Lymphocytic Choriomeningitis Virus Nucleoprotein C-terminal Domain==
-	<StructureSection load='4o6i' size='340' side='right' caption='[[4o6i]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='4o6i' size='340' side='right'caption='[[4o6i]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4o6i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O6I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O6I FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4o6i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lcmv Lcmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O6I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O6I FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4o6h\|4o6h]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4o6h\|4o6h]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">N ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11624 LCMV])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o6i OCA], [http://pdbe.org/4o6i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4o6i RCSB], [http://www.ebi.ac.uk/pdbsum/4o6i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4o6i ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o6i OCA], [http://pdbe.org/4o6i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4o6i RCSB], [http://www.ebi.ac.uk/pdbsum/4o6i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4o6i ProSAT]</span></td></tr>
	</table>		</table>
Line 19:		Line 20:
	</div>		</div>
	<div class="pdbe-citations 4o6i" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4o6i" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Nucleoprotein\|Nucleoprotein]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Lcmv]]
	[[Category: Hastie, K M]]		[[Category: Hastie, K M]]
	[[Category: Saphire, E O]]		[[Category: Saphire, E O]]

OCA at 15:37, 5 August 2016

OCA — Fri, 05 Aug 2016 15:37:11 GMT

←Older revision		Revision as of 15:37, 5 August 2016
Line 1:		Line 1:
		+
	==2.0A crystal structure of Lymphocytic Choriomeningitis Virus Nucleoprotein C-terminal Domain==		==2.0A crystal structure of Lymphocytic Choriomeningitis Virus Nucleoprotein C-terminal Domain==
	<StructureSection load='4o6i' size='340' side='right' caption='[[4o6i]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4o6i' size='340' side='right' caption='[[4o6i]], [[Resolution\|resolution]] 2.00Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4o6h\|4o6h]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4o6h\|4o6h]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o6i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o6i RCSB], [http://www.ebi.ac.uk/pdbsum/4o6i PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o6i OCA], [http://pdbe.org/4o6i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4o6i RCSB], [http://www.ebi.ac.uk/pdbsum/4o6i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4o6i ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4o6i" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 19:58, 25 December 2014

OCA — Thu, 25 Dec 2014 19:58:02 GMT

←Older revision		Revision as of 19:58, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4o6i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O6I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O6I FirstGlance]. <br>		<table><tr><td colspan='2'>[[4o6i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O6I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O6I FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4o6h\|4o6h]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4o6h\|4o6h]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o6i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o6i RCSB], [http://www.ebi.ac.uk/pdbsum/4o6i PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o6i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o6i RCSB], [http://www.ebi.ac.uk/pdbsum/4o6i PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NCAP_LYCVA NCAP_LYCVA]] Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Disables the host innate defense by interfering with beta interferon (IFNB) production through the inhibition of host IRF3 phosphorylation and activation by host IKBKE. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of IRF3, a protein involved in IFN activation pathway, leading to the inhibition of IFNB and IRF3-dependent promoters activation.<ref>PMID:12610166</ref> <ref>PMID:17804508</ref> <ref>PMID:22532683</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Hastie, K M.]]	+	[[Category: Hastie, K M]]
-	[[Category: Saphire, E O.]]	+	[[Category: Saphire, E O]]
-	[[Category: West, B R.]]	+	[[Category: West, B R]]
	[[Category: Exoribonuclease]]		[[Category: Exoribonuclease]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Ribonucleoprotein]]		[[Category: Ribonucleoprotein]]

OCA at 06:32, 2 July 2014

OCA — Wed, 02 Jul 2014 06:32:52 GMT

←Older revision		Revision as of 06:32, 2 July 2014
Line 7:		Line 7:
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o6i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o6i RCSB], [http://www.ebi.ac.uk/pdbsum/4o6i PDBsum]</span></td></tr>		<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o6i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o6i RCSB], [http://www.ebi.ac.uk/pdbsum/4o6i PDBsum]</span></td></tr>
	<table>		<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The X-ray crystal structure of the Lymphocytic choriomeningitis virus nucleoprotein C-terminal immunosuppressive domain (LCMV NPDelta340) was determined to 2.0 A resolution. The structure indicates that LCMV NPDelta340, like the other structurally characterized arenaviral nucleoproteins, adopts the fold of an exonuclease. This structure provides a crucial three-dimensional template for functional exploration of the replication and immunosuppression of this prototypic arenavirus.
		+
		+	Structure of the LCMV nucleoprotein provides a template for understanding arenavirus replication and immunosuppression.,West BR, Hastie KM, Saphire EO Acta Crystallogr D Biol Crystallogr. 2014 Jun;70(Pt 6):1764-9. doi:, 10.1107/S1399004714007883. Epub 2014 May 30. PMID:24914986<ref>PMID:24914986</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 08:54, 11 June 2014

OCA — Wed, 11 Jun 2014 08:54:29 GMT

←Older revision		Revision as of 08:54, 11 June 2014
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==2.0A crystal structure of Lymphocytic Choriomeningitis Virus Nucleoprotein C-terminal Domain==
-		+	<StructureSection load='4o6i' size='340' side='right' caption='[[4o6i]], [[Resolution\|resolution]] 2.00Å' scene=''>
-	~~The entry~~ 4o6i is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4o6i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O6I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O6I FirstGlance]. <br>
-	~~Authors~~: ~~West~~, B.R., Hastie, K.M., Saphire, E.O.	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4o6h\|4o6h]]</td></tr>
-	~~Description~~:	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o6i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o6i RCSB], [http://www.ebi.ac.uk/pdbsum/4o6i PDBsum]</span></td></tr>
		+	<table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Hastie, K M.]]
		+	[[Category: Saphire, E O.]]
		+	[[Category: West, B R.]]
		+	[[Category: Exoribonuclease]]
		+	[[Category: Hydrolase]]
		+	[[Category: Ribonucleoprotein]]

OCA at 08:23, 2 April 2014

OCA — Wed, 02 Apr 2014 08:23:40 GMT

←Older revision		Revision as of 08:23, 2 April 2014
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4o6i is ON HOLD	+	The entry 4o6i is ON HOLD until Paper Publication

	Authors: West, B.R., Hastie, K.M., Saphire, E.O.		Authors: West, B.R., Hastie, K.M., Saphire, E.O.

	Description:		Description:

OCA: Protected "4o6i" [edit=sysop:move=sysop]

OCA — Wed, 08 Jan 2014 09:24:39 GMT

Protected "4o6i" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:24, 8 January 2014

OCA: New page: '''Unreleased structure''' The entry 4o6i is ON HOLD Authors: West, B.R., Hastie, K.M., Saphire, E.O. Description:

OCA — Wed, 08 Jan 2014 09:24:38 GMT

New page: '''Unreleased structure''' The entry 4o6i is ON HOLD Authors: West, B.R., Hastie, K.M., Saphire, E.O. Description:

New page

'''Unreleased structure'''

The entry 4o6i is ON HOLD

Authors: West, B.R., Hastie, K.M., Saphire, E.O.

Description: