4ob6 - Revision history

OCA at 14:55, 8 November 2023

OCA — Wed, 08 Nov 2023 14:55:19 GMT

←Older revision		Revision as of 14:55, 8 November 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4ob6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._ECU1011 Pseudomonas sp. ECU1011]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OB6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OB6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4ob6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._ECU1011 Pseudomonas sp. ECU1011]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OB6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OB6 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=S2T:(2S)-(ACETYLOXY)(2-CHLOROPHENYL)ETHANOIC+ACID'>S2T</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.7Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=S2T:(2S)-(ACETYLOXY)(2-CHLOROPHENYL)ETHANOIC+ACID'>S2T</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ob6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ob6 OCA], [https://pdbe.org/4ob6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ob6 RCSB], [https://www.ebi.ac.uk/pdbsum/4ob6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ob6 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ob6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ob6 OCA], [https://pdbe.org/4ob6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ob6 RCSB], [https://www.ebi.ac.uk/pdbsum/4ob6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ob6 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:15, 25 January 2023

OCA — Wed, 25 Jan 2023 07:15:26 GMT

←Older revision		Revision as of 07:15, 25 January 2023
Line 3:		Line 3:
	<StructureSection load='4ob6' size='340' side='right'caption='[[4ob6]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='4ob6' size='340' side='right'caption='[[4ob6]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ob6]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Pseudomonas_sp.~~_ecu1011~~ Pseudomonas sp. ~~ecu1011~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OB6 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4OB6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ob6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._ECU1011 Pseudomonas sp. ECU1011]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OB6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OB6 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=S2T:(2S)-(ACETYLOXY)(2-CHLOROPHENYL)ETHANOIC+ACID'>S2T</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=S2T:(2S)-(ACETYLOXY)(2-CHLOROPHENYL)ETHANOIC+ACID'>S2T</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ob7\|4ob7]], [[4ob8\|4ob8]], [[4ou4\|4ou4]], [[4ou5\|4ou5]]~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ob6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ob6 OCA], [https://pdbe.org/4ob6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ob6 RCSB], [https://www.ebi.ac.uk/pdbsum/4ob6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ob6 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ob6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ob6 OCA], [~~http~~://pdbe.org/4ob6 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4ob6 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4ob6 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4ob6 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/L7PYQ2_9PSED L7PYQ2_9PSED]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Pseudomonas sp. ~~ecu1011~~]]	+	[[Category: Pseudomonas sp. ECU1011]]
-	[[Category: Chen, Q]]	+	[[Category: Chen Q]]
-	[[Category: Dou, S]]	+	[[Category: Dou S]]
-	[[Category: Kong~~, X D~~]]	+	[[Category: Kong XD]]
-	[[Category: Ma~~, B D~~]]	+	[[Category: Ma BD]]
-	[[Category: Xu~~, J H~~]]	+	[[Category: Xu JH]]
-	[[Category: Zhou~~, J H]]~~	+	[[Category: Zhou JH]]
-	~~[[Category: A/b hydrolase fold]]~~	+
-	~~[[Category: Esterase]]~~	+
-	~~[[Category: Hsl-like family]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 05:23, 13 February 2020

OCA — Thu, 13 Feb 2020 05:23:10 GMT

←Older revision		Revision as of 05:23, 13 February 2020
Line 1:		Line 1:

	==Complex structure of esterase rPPE S159A/W187H and substrate (S)-Ac-CPA==		==Complex structure of esterase rPPE S159A/W187H and substrate (S)-Ac-CPA==
-	<StructureSection load='4ob6' size='340' side='right' caption='[[4ob6]], [[Resolution\|resolution]] 1.70Å' scene=''>	+	<StructureSection load='4ob6' size='340' side='right'caption='[[4ob6]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4ob6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_sp._ecu1011 Pseudomonas sp. ecu1011]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OB6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OB6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4ob6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_sp._ecu1011 Pseudomonas sp. ecu1011]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OB6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OB6 FirstGlance]. <br>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Pseudomonas sp. ecu1011]]		[[Category: Pseudomonas sp. ecu1011]]
	[[Category: Chen, Q]]		[[Category: Chen, Q]]

OCA at 08:23, 22 November 2017

OCA — Wed, 22 Nov 2017 08:23:07 GMT

←Older revision		Revision as of 08:23, 22 November 2017
Line 3:		Line 3:
	<StructureSection load='4ob6' size='340' side='right' caption='[[4ob6]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='4ob6' size='340' side='right' caption='[[4ob6]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ob6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OB6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OB6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ob6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_sp._ecu1011 Pseudomonas sp. ecu1011]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OB6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OB6 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=S2T:(2S)-(ACETYLOXY)(2-CHLOROPHENYL)ETHANOIC+ACID'>S2T</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=S2T:(2S)-(ACETYLOXY)(2-CHLOROPHENYL)ETHANOIC+ACID'>S2T</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ob7\|4ob7]], [[4ob8\|4ob8]], [[4ou4\|4ou4]], [[4ou5\|4ou5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ob7\|4ob7]], [[4ob8\|4ob8]], [[4ou4\|4ou4]], [[4ou5\|4ou5]]</td></tr>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Pseudomonas sp. ecu1011]]
	[[Category: Chen, Q]]		[[Category: Chen, Q]]
	[[Category: Dou, S]]		[[Category: Dou, S]]

OCA at 09:35, 11 August 2016

OCA — Thu, 11 Aug 2016 09:35:12 GMT

←Older revision		Revision as of 09:35, 11 August 2016
Line 1:		Line 1:
		+
	==Complex structure of esterase rPPE S159A/W187H and substrate (S)-Ac-CPA==		==Complex structure of esterase rPPE S159A/W187H and substrate (S)-Ac-CPA==
	<StructureSection load='4ob6' size='340' side='right' caption='[[4ob6]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='4ob6' size='340' side='right' caption='[[4ob6]], [[Resolution\|resolution]] 1.70Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=S2T:(2S)-(ACETYLOXY)(2-CHLOROPHENYL)ETHANOIC+ACID'>S2T</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=S2T:(2S)-(ACETYLOXY)(2-CHLOROPHENYL)ETHANOIC+ACID'>S2T</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ob7\|4ob7]], [[4ob8\|4ob8]], [[4ou4\|4ou4]], [[4ou5\|4ou5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ob7\|4ob7]], [[4ob8\|4ob8]], [[4ou4\|4ou4]], [[4ou5\|4ou5]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ob6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ob6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ob6 RCSB], [http://www.ebi.ac.uk/pdbsum/4ob6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ob6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ob6 OCA], [http://pdbe.org/4ob6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ob6 RCSB], [http://www.ebi.ac.uk/pdbsum/4ob6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ob6 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4ob6" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:00, 5 January 2015

OCA — Mon, 05 Jan 2015 13:00:26 GMT

←Older revision		Revision as of 13:00, 5 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4ob6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OB6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OB6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4ob6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OB6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OB6 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=S2T:(2S)-(ACETYLOXY)(2-CHLOROPHENYL)ETHANOIC+ACID'>S2T</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=S2T:(2S)-(ACETYLOXY)(2-CHLOROPHENYL)ETHANOIC+ACID'>S2T</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ob7\|4ob7]], [[4ob8\|4ob8]], [[4ou4\|4ou4]], [[4ou5\|4ou5]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ob7\|4ob7]], [[4ob8\|4ob8]], [[4ou4\|4ou4]], [[4ou5\|4ou5]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ob6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ob6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ob6 RCSB], [http://www.ebi.ac.uk/pdbsum/4ob6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ob6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ob6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ob6 RCSB], [http://www.ebi.ac.uk/pdbsum/4ob6 PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Chen, Q.]]	+	[[Category: Chen, Q]]
-	[[Category: Dou, S.]]	+	[[Category: Dou, S]]
-	[[Category: Kong, X D.]]	+	[[Category: Kong, X D]]
-	[[Category: Ma, B D.]]	+	[[Category: Ma, B D]]
-	[[Category: Xu, J H.]]	+	[[Category: Xu, J H]]
-	[[Category: Zhou, J H.]]	+	[[Category: Zhou, J H]]
	[[Category: A/b hydrolase fold]]		[[Category: A/b hydrolase fold]]
	[[Category: Esterase]]		[[Category: Esterase]]
	[[Category: Hsl-like family]]		[[Category: Hsl-like family]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 08:00, 23 July 2014

OCA — Wed, 23 Jul 2014 08:00:49 GMT

←Older revision		Revision as of 08:00, 23 July 2014
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Complex structure of esterase rPPE S159A/W187H and substrate (S)-Ac-CPA==
		+	<StructureSection load='4ob6' size='340' side='right' caption='[[4ob6]], [[Resolution\|resolution]] 1.70Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4ob6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OB6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OB6 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=S2T:(2S)-(ACETYLOXY)(2-CHLOROPHENYL)ETHANOIC+ACID'>S2T</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ob7\|4ob7]], [[4ob8\|4ob8]], [[4ou4\|4ou4]], [[4ou5\|4ou5]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ob6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ob6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ob6 RCSB], [http://www.ebi.ac.uk/pdbsum/4ob6 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	A recombinant carboxylesterase (rPPE) from Pseudomonas putida ECU1011 was previously cloned and engineered to give a potential application for resolving chiral alpha-hydroxy acids including mandelic acids and derivatives. Two variants rPPEW187H and rPPED287A showed a approximately 100-fold increase in activity towards rac-2-acetoxy-2-(2'-chlorophenyl) acetate (rac-AcO-CPA), but rPPED287A had a significant decrease in enantioselectivity (E=8.7) compared to rPPEW187H and the wild-type rPPE (rPPEWT) (E>200). Here we report the crystal structures of rPPEWT and rPPEW187H, both by themselves and in complex with the substrate, to elucidate the structural basis of this phenomenon. An inactive mutation of nucleophile residue S159A was introduced to obtain the structure of rPPES159A/W187H complexed with (S)-AcO-CPA. The structural analysis reveals that the side chain of residue Asp287 in rPPEWT would have a potential steric conflict with (S)-AcO-CPA when the substrate binds at the active site of the enzyme. However, the mutation W187H could facilitate the relocation of Asp287, while D287A directly eliminates the hindrance of Asp287, both of which offer sufficient space for the binding and hydrolysis of substrate. Moreover, Asp287 generates one site of the "three-point attachment model" as a hydrogen-bond donor that determines the excellent enantioselectivity of rPPE in chiral recognition, and D287A would obviously destroy the hydrogen bond and result in the low enantioselectivity of rPPED287A.

-	~~The entry 4ob6 is ON HOLD until Paper Publication~~	+	Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition.,Dou S, Kong XD, Ma BD, Chen Q, Zhang J, Zhou J, Xu JH Biochem Biophys Res Commun. 2014 Apr 18;446(4):1145-50. doi:, 10.1016/j.bbrc.2014.03.072. Epub 2014 Mar 27. PMID:24680822<ref>PMID:24680822</ref>

-	~~Authors~~: Dou, S., Kong, X.D., Ma, B.D.~~, Chen, Q., Zhou~~, J.H.~~, Xu~~, J.H.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Complex structure of esterase rPPE S159A~~/~~W187H and substrate (S)~~-~~Ac-CPA~~	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Chen, Q.]]
		+	[[Category: Dou, S.]]
		+	[[Category: Kong, X D.]]
		+	[[Category: Ma, B D.]]
		+	[[Category: Xu, J H.]]
		+	[[Category: Zhou, J H.]]
		+	[[Category: A/b hydrolase fold]]
		+	[[Category: Esterase]]
		+	[[Category: Hsl-like family]]
		+	[[Category: Hydrolase]]

OCA at 16:12, 19 February 2014

OCA — Wed, 19 Feb 2014 16:12:39 GMT

←Older revision		Revision as of 16:12, 19 February 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4ob6 is ON HOLD	+	The entry 4ob6 is ON HOLD until Paper Publication

	Authors: Dou, S., Kong, X.D., Ma, B.D., Chen, Q., Zhou, J.H., Xu, J.H.		Authors: Dou, S., Kong, X.D., Ma, B.D., Chen, Q., Zhou, J.H., Xu, J.H.

	Description: Complex structure of esterase rPPE S159A/W187H and substrate (S)-Ac-CPA		Description: Complex structure of esterase rPPE S159A/W187H and substrate (S)-Ac-CPA

OCA at 07:05, 29 January 2014

OCA — Wed, 29 Jan 2014 07:05:59 GMT

←Older revision		Revision as of 07:05, 29 January 2014
Line 3:		Line 3:
	The entry 4ob6 is ON HOLD		The entry 4ob6 is ON HOLD

-	Authors: Dou S., Kong X. D., Ma B. D., Chen Q., Zhou J. H., Xu J. H.	+	Authors: Dou, S., Kong, X.D., Ma, B.D., Chen, Q., Zhou, J.H., Xu, J.H.

	Description: Complex structure of esterase rPPE S159A/W187H and substrate (S)-Ac-CPA		Description: Complex structure of esterase rPPE S159A/W187H and substrate (S)-Ac-CPA

OCA: Protected "4ob6" [edit=sysop:move=sysop]

OCA — Wed, 15 Jan 2014 07:44:47 GMT

Protected "4ob6" [edit=sysop:move=sysop]

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Revision as of 07:44, 15 January 2014