4ocj - Revision history

OCA at 07:16, 25 January 2023

OCA — Wed, 25 Jan 2023 07:16:50 GMT

←Older revision		Revision as of 07:16, 25 January 2023
Line 3:		Line 3:
	<StructureSection load='4ocj' size='340' side='right'caption='[[4ocj]], [[Resolution\|resolution]] 1.57Å' scene=''>		<StructureSection load='4ocj' size='340' side='right'caption='[[4ocj]], [[Resolution\|resolution]] 1.57Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ocj]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~As_1.2186 As 1.2186~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OCJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4OCJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ocj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bifidobacterium_longum Bifidobacterium longum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OCJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ocj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ocj OCA], [https://pdbe.org/4ocj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ocj RCSB], [https://www.ebi.ac.uk/pdbsum/4ocj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ocj ProSAT]</span></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ock\|4ock]], [[4oco\|4oco]], [[4ocp\|4ocp]], [[4ocq\|4ocq]], [[4ocu\|4ocu]], [[4ocv\|4ocv]]</td></tr>	+
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mdsC, BN57_1851 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=216816 AS 1.2186])</td></tr>	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetylhexosamine_1-kinase N-acetylhexosamine 1-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.162 2.7.1.162] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ocj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ocj OCA], [~~http~~://pdbe.org/4ocj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4ocj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4ocj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4ocj ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/NAHK_BIFL2 NAHK_BIFL2] Phosphorylates both N-acetylglucosamine (GlcNAc) and N-acetylgalactosamine (GalNAc) at similar rates. Involved in the lacto-N-biose I/galacto-N-biose (LNB/GNB) degradation pathway, which is important for host intestinal colonization by bifidobacteria. Also accepts GTP and ITP as phosphate donors. In vitro, can phosphorylate several GlcNAc and GalNAc derivatives.<ref>PMID:17720833</ref> <ref>PMID:19436918</ref> <ref>PMID:19683921</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~As 1 2186~~]]	+	[[Category: Bifidobacterium longum]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: N-acetylhexosamine 1-kinase]]~~	+	[[Category: Chang CY]]
-	[[Category: Chang~~, C Y~~]]	+	[[Category: Li TL]]
-	[[Category: Li~~, T L~~]]	+	[[Category: Liu YC]]
-	[[Category: Liu~~, Y C~~]]	+	[[Category: Lyu SY]]
-	[[Category: Lyu~~, S Y~~]]	+	[[Category: Wang KC]]
-	[[Category: Wang~~, K C~~]]	+	[[Category: Wu CJ]]
-	[[Category: Wu~~, C J]]~~	+
-	~~[[Category: Atp binding]]~~	+
-	~~[[Category: Kinase]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 08:45, 10 April 2019

OCA — Wed, 10 Apr 2019 08:45:47 GMT

←Older revision		Revision as of 08:45, 10 April 2019
Line 1:		Line 1:

	==N-acetylhexosamine 1-phosphate kinase in complex with GlcNAc==		==N-acetylhexosamine 1-phosphate kinase in complex with GlcNAc==
-	<StructureSection load='4ocj' size='340' side='right' caption='[[4ocj]], [[Resolution\|resolution]] 1.57Å' scene=''>	+	<StructureSection load='4ocj' size='340' side='right'caption='[[4ocj]], [[Resolution\|resolution]] 1.57Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ocj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OCJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OCJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ocj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/As_1.2186 As 1.2186]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OCJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OCJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ock\|4ock]], [[4oco\|4oco]], [[4ocp\|4ocp]], [[4ocq\|4ocq]], [[4ocu\|4ocu]], [[4ocv\|4ocv]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ock\|4ock]], [[4oco\|4oco]], [[4ocp\|4ocp]], [[4ocq\|4ocq]], [[4ocu\|4ocu]], [[4ocv\|4ocv]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mdsC, BN57_1851 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=216816 AS 1.2186])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetylhexosamine_1-kinase N-acetylhexosamine 1-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.162 2.7.1.162] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetylhexosamine_1-kinase N-acetylhexosamine 1-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.162 2.7.1.162] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ocj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ocj OCA], [http://pdbe.org/4ocj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ocj RCSB], [http://www.ebi.ac.uk/pdbsum/4ocj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ocj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ocj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ocj OCA], [http://pdbe.org/4ocj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ocj RCSB], [http://www.ebi.ac.uk/pdbsum/4ocj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ocj ProSAT]</span></td></tr>
Line 23:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: As 1 2186]]
		+	[[Category: Large Structures]]
	[[Category: N-acetylhexosamine 1-kinase]]		[[Category: N-acetylhexosamine 1-kinase]]
	[[Category: Chang, C Y]]		[[Category: Chang, C Y]]

OCA at 18:13, 11 August 2016

OCA — Thu, 11 Aug 2016 18:13:00 GMT

←Older revision		Revision as of 18:13, 11 August 2016
Line 1:		Line 1:
		+
	==N-acetylhexosamine 1-phosphate kinase in complex with GlcNAc==		==N-acetylhexosamine 1-phosphate kinase in complex with GlcNAc==
	<StructureSection load='4ocj' size='340' side='right' caption='[[4ocj]], [[Resolution\|resolution]] 1.57Å' scene=''>		<StructureSection load='4ocj' size='340' side='right' caption='[[4ocj]], [[Resolution\|resolution]] 1.57Å' scene=''>
Line 7:		Line 8:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ock\|4ock]], [[4oco\|4oco]], [[4ocp\|4ocp]], [[4ocq\|4ocq]], [[4ocu\|4ocu]], [[4ocv\|4ocv]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ock\|4ock]], [[4oco\|4oco]], [[4ocp\|4ocp]], [[4ocq\|4ocq]], [[4ocu\|4ocu]], [[4ocv\|4ocv]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetylhexosamine_1-kinase N-acetylhexosamine 1-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.162 2.7.1.162] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetylhexosamine_1-kinase N-acetylhexosamine 1-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.162 2.7.1.162] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ocj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ocj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ocj RCSB], [http://www.ebi.ac.uk/pdbsum/4ocj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ocj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ocj OCA], [http://pdbe.org/4ocj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ocj RCSB], [http://www.ebi.ac.uk/pdbsum/4ocj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ocj ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4ocj" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:22, 20 January 2015

OCA — Tue, 20 Jan 2015 08:22:26 GMT

←Older revision		Revision as of 08:22, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4ocj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OCJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OCJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[4ocj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OCJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OCJ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ock\|4ock]], [[4oco\|4oco]], [[4ocp\|4ocp]], [[4ocq\|4ocq]], [[4ocu\|4ocu]], [[4ocv\|4ocv]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ock\|4ock]], [[4oco\|4oco]], [[4ocp\|4ocp]], [[4ocq\|4ocq]], [[4ocu\|4ocu]], [[4ocv\|4ocv]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetylhexosamine_1-kinase N-acetylhexosamine 1-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.162 2.7.1.162] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetylhexosamine_1-kinase N-acetylhexosamine 1-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.162 2.7.1.162] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ocj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ocj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ocj RCSB], [http://www.ebi.ac.uk/pdbsum/4ocj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ocj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ocj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ocj RCSB], [http://www.ebi.ac.uk/pdbsum/4ocj PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: N-acetylhexosamine 1-kinase]]		[[Category: N-acetylhexosamine 1-kinase]]
-	[[Category: Chang, C Y.]]	+	[[Category: Chang, C Y]]
-	[[Category: Li, T L.]]	+	[[Category: Li, T L]]
-	[[Category: Liu, Y C.]]	+	[[Category: Liu, Y C]]
-	[[Category: Lyu, S Y.]]	+	[[Category: Lyu, S Y]]
-	[[Category: Wang, K C.]]	+	[[Category: Wang, K C]]
-	[[Category: Wu, C J.]]	+	[[Category: Wu, C J]]
	[[Category: Atp binding]]		[[Category: Atp binding]]
	[[Category: Kinase]]		[[Category: Kinase]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 06:38, 24 September 2014

OCA — Wed, 24 Sep 2014 06:38:41 GMT

←Older revision		Revision as of 06:38, 24 September 2014
Line 2:		Line 2:
	<StructureSection load='4ocj' size='340' side='right' caption='[[4ocj]], [[Resolution\|resolution]] 1.57Å' scene=''>		<StructureSection load='4ocj' size='340' side='right' caption='[[4ocj]], [[Resolution\|resolution]] 1.57Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ocj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OCJ OCA]. <br>	+	<table><tr><td colspan='2'>[[4ocj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OCJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OCJ FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene><br>		</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene><br>
	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ock\|4ock]], [[4oco\|4oco]], [[4ocp\|4ocp]], [[4ocq\|4ocq]], [[4ocu\|4ocu]], [[4ocv\|4ocv]]</td></tr>		<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ock\|4ock]], [[4oco\|4oco]], [[4ocp\|4ocp]], [[4ocq\|4ocq]], [[4ocu\|4ocu]], [[4ocv\|4ocv]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/~~Glucokinase Glucokinase~~], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>	+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetylhexosamine_1-kinase N-acetylhexosamine 1-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.162 2.7.1.162] </span></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ocj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ocj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ocj RCSB], [http://www.ebi.ac.uk/pdbsum/4ocj PDBsum]</span></td></tr>		<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ocj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ocj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ocj RCSB], [http://www.ebi.ac.uk/pdbsum/4ocj PDBsum]</span></td></tr>
	<table>		<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Utilization of N-acetylhexosamine in bifidobacteria requires the specific lacto-N-biose/galacto-N-biose pathway, a pathway differing from the Leloir pathway while establishing symbiosis between humans and bifidobacteria. The gene lnpB in the pathway encodes a novel hexosamine kinase NahK, which catalyzes the formation of N-acetylhexosamine 1-phosphate (GlcNAc-1P/GalNAc-1P). In this report, seven three-dimensional structures of NahK in complex with GlcNAc, GalNAc, GlcNAc-1P, GlcNAc/AMPPNP and GlcNAc-1P/ADP from both Bifidobacterium longum (JCM1217) and B. infantis (ATCC15697) were solved at resolutions of 1.5-2.2 A. NahK is a monomer in solution, and its polypeptide folds in a crescent-like architecture subdivided into two domains by a deep cleft. The NahK structures presented here represent the first multiple reaction complexes of the enzyme. This structural information reveals the molecular basis for the recognition of the given substrates and products, GlcNAc/GalNAc, GlcNAc-1P/GalNAc-1P, ATP/ADP and Mg(2+), and provides insights into the catalytic mechanism, enabling NahK and mutants thereof to form a choice of biocatalysts for enzymatic and chemoenzymatic synthesis of carbohydrates.
		+
		+	Insights into the binding specificity and catalytic mechanism of N-acetylhexosamine 1-phosphate kinases through multiple reaction complexes.,Wang KC, Lyu SY, Liu YC, Chang CY, Wu CJ, Li TL Acta Crystallogr D Biol Crystallogr. 2014 May;70(Pt 5):1401-10. doi:, 10.1107/S1399004714004209. Epub 2014 Apr 30. PMID:24816108<ref>PMID:24816108</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 07:27, 14 May 2014

OCA — Wed, 14 May 2014 07:27:02 GMT

←Older revision		Revision as of 07:27, 14 May 2014
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==N-acetylhexosamine 1-phosphate kinase in complex with GlcNAc==
-		+	<StructureSection load='4ocj' size='340' side='right' caption='[[4ocj]], [[Resolution\|resolution]] 1.57Å' scene=''>
-	~~The entry~~ 4ocj is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4ocj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OCJ OCA]. <br>
-	~~Authors~~: Li, T.L., ~~Wang~~, K.C., ~~Lyu~~, S.Y., Liu, Y.C., ~~Chang, C.~~Y., Wu, C.J.	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	~~Description~~: ~~N-acetylhexosamine 1-phosphate kinase in complex with GlcNAc~~	+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ock\|4ock]], [[4oco\|4oco]], [[4ocp\|4ocp]], [[4ocq\|4ocq]], [[4ocu\|4ocu]], [[4ocv\|4ocv]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ocj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ocj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ocj RCSB], [http://www.ebi.ac.uk/pdbsum/4ocj PDBsum]</span></td></tr>
		+	<table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: N-acetylhexosamine 1-kinase]]
		+	[[Category: Chang, C Y.]]
		+	[[Category: Li, T L.]]
		+	[[Category: Liu, Y C.]]
		+	[[Category: Lyu, S Y.]]
		+	[[Category: Wang, K C.]]
		+	[[Category: Wu, C J.]]
		+	[[Category: Atp binding]]
		+	[[Category: Kinase]]
		+	[[Category: Transferase]]

OCA at 04:50, 13 February 2014

OCA — Thu, 13 Feb 2014 04:50:07 GMT

←Older revision		Revision as of 04:50, 13 February 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4ocj is ON HOLD	+	The entry 4ocj is ON HOLD until Paper Publication

	Authors: Li, T.L., Wang, K.C., Lyu, S.Y., Liu, Y.C., Chang, C.Y., Wu, C.J.		Authors: Li, T.L., Wang, K.C., Lyu, S.Y., Liu, Y.C., Chang, C.Y., Wu, C.J.

	Description: N-acetylhexosamine 1-phosphate kinase in complex with GlcNAc		Description: N-acetylhexosamine 1-phosphate kinase in complex with GlcNAc

OCA at 07:06, 29 January 2014

OCA — Wed, 29 Jan 2014 07:06:43 GMT

←Older revision		Revision as of 07:06, 29 January 2014
Line 3:		Line 3:
	The entry 4ocj is ON HOLD		The entry 4ocj is ON HOLD

-	Authors: ~~Tsung-Lin~~ Li, ~~Kuei-Chen~~ Wang, ~~Syue-Yi~~ Lyu, ~~Yu-Chen~~ Liu, ~~Chin-Yuan Chang~~, Chang~~-Jer~~ Wu	+	Authors: Li, T.L., Wang, K.C., Lyu, S.Y., Liu, Y.C., Chang, C.Y., Wu, C.J.

-	Description: N-acetylhexosamine 1-phosphate ~~kinases~~ in complex with GlcNAc	+	Description: N-acetylhexosamine 1-phosphate kinase in complex with GlcNAc

OCA: Protected "4ocj" [edit=sysop:move=sysop]

OCA — Wed, 15 Jan 2014 07:46:33 GMT

Protected "4ocj" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:46, 15 January 2014

OCA: New page: '''Unreleased structure''' The entry 4ocj is ON HOLD Authors: Tsung-Lin Li, Kuei-Chen Wang, Syue-Yi Lyu, Yu-Chen Liu, Chin-Yuan Chang, Chang-Jer Wu Description: N-acetylhexosamine 1-ph...

OCA — Wed, 15 Jan 2014 07:46:32 GMT

New page: '''Unreleased structure''' The entry 4ocj is ON HOLD Authors: Tsung-Lin Li, Kuei-Chen Wang, Syue-Yi Lyu, Yu-Chen Liu, Chin-Yuan Chang, Chang-Jer Wu Description: N-acetylhexosamine 1-ph...

New page

'''Unreleased structure'''

The entry 4ocj is ON HOLD

Authors: Tsung-Lin Li, Kuei-Chen Wang, Syue-Yi Lyu, Yu-Chen Liu, Chin-Yuan Chang, Chang-Jer Wu

Description: N-acetylhexosamine 1-phosphate kinases in complex with GlcNAc