4ott - Revision history

OCA at 17:18, 20 September 2023

OCA — Wed, 20 Sep 2023 17:18:48 GMT

←Older revision		Revision as of 17:18, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4ott]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis] and [https://en.wikipedia.org/wiki/Bacillus_licheniformis_DSM_13_=_ATCC_14580 Bacillus licheniformis DSM 13 = ATCC 14580]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OTT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OTT FirstGlance]. <br>		<table><tr><td colspan='2'>[[4ott]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis] and [https://en.wikipedia.org/wiki/Bacillus_licheniformis_DSM_13_=_ATCC_14580 Bacillus licheniformis DSM 13 = ATCC 14580]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OTT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OTT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.98Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ott FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ott OCA], [https://pdbe.org/4ott PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ott RCSB], [https://www.ebi.ac.uk/pdbsum/4ott PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ott ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ott FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ott OCA], [https://pdbe.org/4ott PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ott RCSB], [https://www.ebi.ac.uk/pdbsum/4ott PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ott ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:45, 25 January 2023

OCA — Wed, 25 Jan 2023 07:45:25 GMT

←Older revision		Revision as of 07:45, 25 January 2023
Line 3:		Line 3:
	<StructureSection load='4ott' size='340' side='right'caption='[[4ott]], [[Resolution\|resolution]] 2.98Å' scene=''>		<StructureSection load='4ott' size='340' side='right'caption='[[4ott]], [[Resolution\|resolution]] 2.98Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ott]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"clostridium_licheniforme"_weigmann_1898 "clostridium licheniforme" weigmann 1898~~] and [~~http~~://en.wikipedia.org/wiki/~~Bacld Bacld~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OTT OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4OTT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ott]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis] and [https://en.wikipedia.org/wiki/Bacillus_licheniformis_DSM_13_=_ATCC_14580 Bacillus licheniformis DSM 13 = ATCC 14580]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OTT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OTT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4otu\|4otu]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ott FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ott OCA], [https://pdbe.org/4ott PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ott RCSB], [https://www.ebi.ac.uk/pdbsum/4ott PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ott ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ggt, BL03798, BLi01364 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=279010 BACLD])</td></tr>	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Gamma-glutamyltransferase Gamma-glutamyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.2 2.3.2.2] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ott FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ott OCA], [~~http~~://pdbe.org/4ott PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4ott RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4ott PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4ott ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A9YTT0_BACLI A9YTT0_BACLI]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Clostridium licheniforme weigmann 1898~~]]	+	[[Category: Bacillus licheniformis]]
-	[[Category: ~~Bacld]]~~	+	[[Category: Bacillus licheniformis DSM 13 = ATCC 14580]]
-	~~[[Category: Gamma-glutamyltransferase~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Merlino, A]]	+	[[Category: Merlino A]]
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Ntn hydrolase~~]]	+

OCA at 08:16, 17 April 2019

OCA — Wed, 17 Apr 2019 08:16:23 GMT

←Older revision		Revision as of 08:16, 17 April 2019
Line 1:		Line 1:

	==Crystal structure of the gamma-glutamyltranspeptidase from Bacillus licheniformis.==		==Crystal structure of the gamma-glutamyltranspeptidase from Bacillus licheniformis.==
-	<StructureSection load='4ott' size='340' side='right' caption='[[4ott]], [[Resolution\|resolution]] 2.98Å' scene=''>	+	<StructureSection load='4ott' size='340' side='right'caption='[[4ott]], [[Resolution\|resolution]] 2.98Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ott]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OTT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OTT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ott]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"clostridium_licheniforme"_weigmann_1898 "clostridium licheniforme" weigmann 1898] and [http://en.wikipedia.org/wiki/Bacld Bacld]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OTT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OTT FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4otu\|4otu]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4otu\|4otu]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ggt, BL03798, BLi01364 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=279010 BACLD])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Gamma-glutamyltransferase Gamma-glutamyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.2 2.3.2.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Gamma-glutamyltransferase Gamma-glutamyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.2 2.3.2.2] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ott FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ott OCA], [http://pdbe.org/4ott PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ott RCSB], [http://www.ebi.ac.uk/pdbsum/4ott PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ott ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ott FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ott OCA], [http://pdbe.org/4ott PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ott RCSB], [http://www.ebi.ac.uk/pdbsum/4ott PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ott ProSAT]</span></td></tr>
Line 22:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Clostridium licheniforme weigmann 1898]]
		+	[[Category: Bacld]]
	[[Category: Gamma-glutamyltransferase]]		[[Category: Gamma-glutamyltransferase]]
		+	[[Category: Large Structures]]
	[[Category: Merlino, A]]		[[Category: Merlino, A]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Ntn hydrolase]]		[[Category: Ntn hydrolase]]

OCA at 21:21, 11 August 2016

OCA — Thu, 11 Aug 2016 21:21:31 GMT

←Older revision		Revision as of 21:21, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of the gamma-glutamyltranspeptidase from Bacillus licheniformis.==		==Crystal structure of the gamma-glutamyltranspeptidase from Bacillus licheniformis.==
	<StructureSection load='4ott' size='340' side='right' caption='[[4ott]], [[Resolution\|resolution]] 2.98Å' scene=''>		<StructureSection load='4ott' size='340' side='right' caption='[[4ott]], [[Resolution\|resolution]] 2.98Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4otu\|4otu]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4otu\|4otu]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Gamma-glutamyltransferase Gamma-glutamyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.2 2.3.2.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Gamma-glutamyltransferase Gamma-glutamyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.2 2.3.2.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ott FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ott OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ott RCSB], [http://www.ebi.ac.uk/pdbsum/4ott PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ott FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ott OCA], [http://pdbe.org/4ott PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ott RCSB], [http://www.ebi.ac.uk/pdbsum/4ott PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ott ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4ott" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:12, 5 January 2015

OCA — Mon, 05 Jan 2015 13:12:35 GMT

←Older revision		Revision as of 13:12, 5 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4ott]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OTT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OTT FirstGlance]. <br>		<table><tr><td colspan='2'>[[4ott]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OTT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OTT FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4otu\|4otu]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4otu\|4otu]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Gamma-glutamyltransferase Gamma-glutamyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.2 2.3.2.2] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Gamma-glutamyltransferase Gamma-glutamyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.2 2.3.2.2] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ott FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ott OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ott RCSB], [http://www.ebi.ac.uk/pdbsum/4ott PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ott FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ott OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ott RCSB], [http://www.ebi.ac.uk/pdbsum/4ott PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Gamma-glutamyltransferase]]		[[Category: Gamma-glutamyltransferase]]
-	[[Category: Merlino, A.]]	+	[[Category: Merlino, A]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Ntn hydrolase]]		[[Category: Ntn hydrolase]]

OCA at 07:59, 23 July 2014

OCA — Wed, 23 Jul 2014 07:59:06 GMT

←Older revision		Revision as of 07:59, 23 July 2014
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal structure of the gamma-glutamyltranspeptidase from Bacillus licheniformis.==
		+	<StructureSection load='4ott' size='340' side='right' caption='[[4ott]], [[Resolution\|resolution]] 2.98Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4ott]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OTT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OTT FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4otu\|4otu]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Gamma-glutamyltransferase Gamma-glutamyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.2 2.3.2.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ott FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ott OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ott RCSB], [http://www.ebi.ac.uk/pdbsum/4ott PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	gamma-Glutamyltranspeptidases (gamma-GTs) cleave the gamma-glutamyl amide bond of glutathione and transfer the released gamma-glutamyl group to water (hydrolysis) or acceptor amino acids (transpeptidation). These ubiquitous enzymes play a key role in the biosynthesis and degradation of glutathione, and in xenobiotic detoxification. Here we report the 3A resolution crystal structure of Bacillus licheniformis gamma-GT (BlGT) and that of its complex with l-Glu. X-ray structures confirm that BlGT belongs to the N-terminal nucleophilic hydrolase superfamily and reveal that the protein possesses an opened active site cleft similar to that reported for the homologous enzyme from Bacillus subtilis, but different from those observed for human gamma-GT and for gamma-GTs from other microorganisms. Data suggest that the binding of l-Glu induces a reordering of the C-terminal tail of BlGT large subunit and allow the identification of a cluster of acid residues that are potentially involved in the recognition of a metal ion. The role of these residues on the conformational stability of BlGT has been studied by characterizing the autoprocessing, enzymatic activity, chemical and thermal denaturation of four new Ala single mutants. The results show that replacement of Asp568 with an Ala affects both the autoprocessing and structural stability of the protein.

-	~~The entry 4ott is ON HOLD until Paper Publication~~	+	Low resolution X-ray structure of gamma-glutamyltranspeptidase from Bacillus licheniformis: Opened active site cleft and a cluster of acid residues potentially involved in the recognition of a metal ion.,Lin LL, Chen YY, Chi MC, Merlino A Biochim Biophys Acta. 2014 Apr 26;1844(9):1523-1529. doi:, 10.1016/j.bbapap.2014.04.016. PMID:24780583<ref>PMID:24780583</ref>

-	~~Authors~~: Merlino, A.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Crystal structure of the gamma-glutamyltranspeptidase from Bacillus licheniformis.~~	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Gamma-glutamyltransferase]]
		+	[[Category: Merlino, A.]]
		+	[[Category: Hydrolase]]
		+	[[Category: Ntn hydrolase]]

OCA at 12:21, 12 March 2014

OCA — Wed, 12 Mar 2014 12:21:21 GMT

←Older revision		Revision as of 12:21, 12 March 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4ott is ON HOLD	+	The entry 4ott is ON HOLD until Paper Publication

	Authors: Merlino, A.		Authors: Merlino, A.

	Description: Crystal structure of the gamma-glutamyltranspeptidase from Bacillus licheniformis.		Description: Crystal structure of the gamma-glutamyltranspeptidase from Bacillus licheniformis.

OCA: Protected "4ott" [edit=sysop:move=sysop]

OCA — Mon, 03 Mar 2014 16:51:35 GMT

Protected "4ott" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:51, 3 March 2014

OCA: New page: '''Unreleased structure''' The entry 4ott is ON HOLD Authors: Merlino, A. Description: Crystal structure of the gamma-glutamyltranspeptidase from Bacillus licheniformis.

OCA — Mon, 03 Mar 2014 16:51:34 GMT

New page: '''Unreleased structure''' The entry 4ott is ON HOLD Authors: Merlino, A. Description: Crystal structure of the gamma-glutamyltranspeptidase from Bacillus licheniformis.

New page

'''Unreleased structure'''

The entry 4ott is ON HOLD

Authors: Merlino, A.

Description: Crystal structure of the gamma-glutamyltranspeptidase from Bacillus licheniformis.