4p05 - Revision history

OCA at 07:07, 27 September 2023

OCA — Wed, 27 Sep 2023 07:07:53 GMT

←Older revision		Revision as of 07:07, 27 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4p05]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_CFT073 Escherichia coli CFT073]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P05 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4P05 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4p05]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_CFT073 Escherichia coli CFT073]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P05 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4P05 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4NS:4-NITROPHENYL+SULFATE'>4NS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.05Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4NS:4-NITROPHENYL+SULFATE'>4NS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4p05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p05 OCA], [https://pdbe.org/4p05 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4p05 RCSB], [https://www.ebi.ac.uk/pdbsum/4p05 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4p05 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4p05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p05 OCA], [https://pdbe.org/4p05 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4p05 RCSB], [https://www.ebi.ac.uk/pdbsum/4p05 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4p05 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 12:34, 1 February 2023

OCA — Wed, 01 Feb 2023 12:34:48 GMT

←Older revision		Revision as of 12:34, 1 February 2023
Line 1:		Line 1:

	==Bacterial arylsulfate sulfotransferase (ASST) H436N mutant with 4-nitrophenyl sulfate (PNS) in the active site==		==Bacterial arylsulfate sulfotransferase (ASST) H436N mutant with 4-nitrophenyl sulfate (PNS) in the active site==
-	<StructureSection load='4p05' size='340' side='right' caption='[[4p05]], [[Resolution\|resolution]] 2.05Å' scene=''>	+	<StructureSection load='4p05' size='340' side='right'caption='[[4p05]], [[Resolution\|resolution]] 2.05Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4p05]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Ecol6 Ecol6~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P05 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4P05 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4p05]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_CFT073 Escherichia coli CFT073]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P05 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4P05 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4NS:4-NITROPHENYL+SULFATE'>4NS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4NS:4-NITROPHENYL+SULFATE'>4NS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ets\|3ets]], [[3ett\|3ett]], [[3elq\|3elq]], [[4p04\|4p04]], [[4p06\|4p06]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4p05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p05 OCA], [https://pdbe.org/4p05 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4p05 RCSB], [https://www.ebi.ac.uk/pdbsum/4p05 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4p05 ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">assT, LF82_506 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=199310 ECOL6])</td></tr>	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aryl-sulfate_sulfotransferase Aryl-sulfate sulfotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.2.22 2.8.2.22] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4p05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p05 OCA], [~~http~~://pdbe.org/4p05 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4p05 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4p05 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4p05 ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~E2QE64_ECOLX E2QE64_ECOLX]~~] Catalyzes the transfer of sulfuryl groups between phenolic compounds ~~(By similarity)~~.[HAMAP-Rule:MF_00933]	+	[https://www.uniprot.org/uniprot/A0A0D6H805_ECOLX A0A0D6H805_ECOLX] Catalyzes the transfer of sulfuryl groups between phenolic compounds.[HAMAP-Rule:MF_00933]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 4p05" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4p05" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Sulfotransferase 3D structures\|Sulfotransferase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Aryl-sulfate sulfotransferase~~]]	+	[[Category: Escherichia coli CFT073]]
-	[[Category: ~~Ecol6~~]]	+	[[Category: Large Structures]]
-	[[Category: Glockshuber, R]]	+	[[Category: Glockshuber R]]
-	[[Category: Malojcic, G]]	+	[[Category: Malojcic G]]
-	[[Category: Owen~~, R L]]~~	+	[[Category: Owen RL]]
-	~~[[Category: Active site mutant]]~~	+
-	~~[[Category: Beta propeller]]~~	+
-	~~[[Category: Sulfotransferase]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 09:03, 1 November 2017

OCA — Wed, 01 Nov 2017 09:03:52 GMT

←Older revision		Revision as of 09:03, 1 November 2017
Line 21:		Line 21:
	</div>		</div>
	<div class="pdbe-citations 4p05" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4p05" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Sulfotransferase\|Sulfotransferase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 23:49, 4 August 2016

OCA — Thu, 04 Aug 2016 23:49:34 GMT

←Older revision		Revision as of 23:49, 4 August 2016
Line 1:		Line 1:
		+
	==Bacterial arylsulfate sulfotransferase (ASST) H436N mutant with 4-nitrophenyl sulfate (PNS) in the active site==		==Bacterial arylsulfate sulfotransferase (ASST) H436N mutant with 4-nitrophenyl sulfate (PNS) in the active site==
	<StructureSection load='4p05' size='340' side='right' caption='[[4p05]], [[Resolution\|resolution]] 2.05Å' scene=''>		<StructureSection load='4p05' size='340' side='right' caption='[[4p05]], [[Resolution\|resolution]] 2.05Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">assT, LF82_506 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=199310 ECOL6])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">assT, LF82_506 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=199310 ECOL6])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aryl-sulfate_sulfotransferase Aryl-sulfate sulfotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.2.22 2.8.2.22] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aryl-sulfate_sulfotransferase Aryl-sulfate sulfotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.2.22 2.8.2.22] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p05 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p05 RCSB], [http://www.ebi.ac.uk/pdbsum/4p05 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p05 OCA], [http://pdbe.org/4p05 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4p05 RCSB], [http://www.ebi.ac.uk/pdbsum/4p05 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4p05 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4p05" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 20:52, 24 December 2014

OCA — Wed, 24 Dec 2014 20:52:27 GMT

←Older revision		Revision as of 20:52, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4p05]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecol6 Ecol6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P05 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P05 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4p05]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecol6 Ecol6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P05 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P05 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4NS:4-NITROPHENYL+SULFATE'>4NS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4NS:4-NITROPHENYL+SULFATE'>4NS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ets\|3ets]], [[3ett\|3ett]], [[3elq\|3elq]], [[4p04\|4p04]], [[4p06\|4p06]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ets\|3ets]], [[3ett\|3ett]], [[3elq\|3elq]], [[4p04\|4p04]], [[4p06\|4p06]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">assT, LF82_506 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=199310 ECOL6])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">assT, LF82_506 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=199310 ECOL6])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aryl-sulfate_sulfotransferase Aryl-sulfate sulfotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.2.22 2.8.2.22] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aryl-sulfate_sulfotransferase Aryl-sulfate sulfotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.2.22 2.8.2.22] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p05 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p05 RCSB], [http://www.ebi.ac.uk/pdbsum/4p05 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p05 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p05 RCSB], [http://www.ebi.ac.uk/pdbsum/4p05 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/E2QE64_ECOLX E2QE64_ECOLX]] Catalyzes the transfer of sulfuryl groups between phenolic compounds (By similarity).[HAMAP-Rule:MF_00933]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 28:
	[[Category: Aryl-sulfate sulfotransferase]]		[[Category: Aryl-sulfate sulfotransferase]]
	[[Category: Ecol6]]		[[Category: Ecol6]]
-	[[Category: Glockshuber, R.]]	+	[[Category: Glockshuber, R]]
-	[[Category: Malojcic, G.]]	+	[[Category: Malojcic, G]]
-	[[Category: Owen, R L.]]	+	[[Category: Owen, R L]]
	[[Category: Active site mutant]]		[[Category: Active site mutant]]
	[[Category: Beta propeller]]		[[Category: Beta propeller]]
	[[Category: Sulfotransferase]]		[[Category: Sulfotransferase]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 22:34, 1 October 2014

OCA — Wed, 01 Oct 2014 22:34:04 GMT

←Older revision		Revision as of 22:34, 1 October 2014
Line 32:		Line 32:
	[[Category: Beta propeller]]		[[Category: Beta propeller]]
	[[Category: Sulfotransferase]]		[[Category: Sulfotransferase]]
		+	[[Category: Transferase]]

OCA at 07:14, 11 June 2014

OCA — Wed, 11 Jun 2014 07:14:37 GMT

←Older revision		Revision as of 07:14, 11 June 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4p05\| PDB=4p05 \| SCENE= }}~~	+	==Bacterial arylsulfate sulfotransferase (ASST) H436N mutant with 4-nitrophenyl sulfate (PNS) in the active site==
-	===Bacterial arylsulfate sulfotransferase (ASST) H436N mutant with 4-nitrophenyl sulfate (PNS) in the active site===	+	<StructureSection load='4p05' size='340' side='right' caption='[[4p05]], [[Resolution\|resolution]] 2.05Å' scene=''>
-	~~{{ABSTRACT_PUBMED_24601529}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4p05]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecol6 Ecol6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P05 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P05 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4NS:4-NITROPHENYL+SULFATE'>4NS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ets\|3ets]], [[3ett\|3ett]], [[3elq\|3elq]], [[4p04\|4p04]], [[4p06\|4p06]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">assT, LF82_506 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=199310 ECOL6])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aryl-sulfate_sulfotransferase Aryl-sulfate sulfotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.2.22 2.8.2.22] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p05 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p05 RCSB], [http://www.ebi.ac.uk/pdbsum/4p05 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Bacterial aryl sulfotransferases (ASSTs) catalyze sulfotransfer from a phenolic sulfate to a phenol. These enzymes are frequently found in pathogens and upregulated during infection. Their mechanistic understanding is very limited, and their natural substrates are unknown. Here, the crystal structures of Escherichia coli CFT073 ASST trapped in its presulfurylation state with model donor substrates bound in the active site are reported, which reveal the molecular interactions governing substrate recognition. Furthermore, spectroscopic titrations with donor substrates and sulfurylation kinetics of ASST illustrate that this enzyme binds substrates in a 1:1 stoichiometry and that the active sites of the ASST homooligomer act independently. Mass spectrometry and crystallographic experiments of ASST incubated with human urine demonstrate that urine contains a sulfuryl donor substrate. In addition, we examined the capability of the two paralogous dithiol oxidases present in uropathogenic E. coli CFT073, DsbA, and the ASST-specific enzyme DsbL, to introduce the single, conserved disulfide bond into ASST. We show that DsbA and DsbL introduce the disulfide bond into unfolded ASST at similar rates. Hence, a chaperone effect of DsbL, not present in DsbA, appears to be responsible for the dependence of efficient ASST folding on DsbL in vivo. The conservation of paralogous dithiol oxidases with different substrate specificities in certain bacterial strains may therefore be a consequence of the complex folding pathways of their substrate proteins.

-	~~==Function==~~	+	Structural and Mechanistic Insights into the PAPS-Independent Sulfotransfer Catalyzed by Bacterial Aryl Sulfotransferase and the Role of the DsbL/DsbI System in Its Folding.,Malojcic G, Owen RL, Glockshuber R Biochemistry. 2014 Mar 25;53(11):1870-7. doi: 10.1021/bi401725j. Epub 2014 Mar, 13. PMID:24601529<ref>PMID:24601529</ref>
-	~~[[http:~~/~~/www~~.~~uniprot~~.~~org/uniprot/E2QE64_ECOLX E2QE64_ECOLX]] Catalyzes the transfer of sulfuryl groups between phenolic compounds~~ (~~By similarity~~)~~.[HAMAP~~-~~Rule~~:~~MF_00933]~~	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[4p05]] is~~ a ~~2 chain structure~~. ~~Full crystallographic information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=4P05 OCA].~~	+	</div>

-	==~~Reference~~==	+	==See Also==
-	~~<ref group~~=~~"xtra">PMID:024601529</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	*[[Sulfotransferase\|Sulfotransferase]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Aryl-sulfate sulfotransferase]]		[[Category: Aryl-sulfate sulfotransferase]]
		+	[[Category: Ecol6]]
	[[Category: Glockshuber, R.]]		[[Category: Glockshuber, R.]]
	[[Category: Malojcic, G.]]		[[Category: Malojcic, G.]]

OCA at 09:25, 26 March 2014

OCA — Wed, 26 Mar 2014 09:25:59 GMT

←Older revision		Revision as of 09:25, 26 March 2014
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4p05\| PDB=4p05 \| SCENE= }}
		+	===Bacterial arylsulfate sulfotransferase (ASST) H436N mutant with 4-nitrophenyl sulfate (PNS) in the active site===
		+	{{ABSTRACT_PUBMED_24601529}}

-	~~The entry 4p05 is ON HOLD~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/E2QE64_ECOLX E2QE64_ECOLX]] Catalyzes the transfer of sulfuryl groups between phenolic compounds (By similarity).[HAMAP-Rule:MF_00933]

-	~~Authors~~: ~~Malojcic, G~~.~~, Owen, R~~.L.~~, Glockshuber, R~~.	+	==About this Structure==
		+	[[4p05]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P05 OCA].

-	~~Description~~: ~~Bacterial arylsulfate sulfotransferase (ASST) H436N mutant with 4~~-~~nitrophenyl~~ sulfate ~~(PNS) in the active~~ site	+	==Reference==
		+	<ref group="xtra">PMID:024601529</ref><references group="xtra"/><references/>
		+	[[Category: Aryl-sulfate sulfotransferase]]
		+	[[Category: Glockshuber, R.]]
		+	[[Category: Malojcic, G.]]
		+	[[Category: Owen, R L.]]
		+	[[Category: Active site mutant]]
		+	[[Category: Beta propeller]]
		+	[[Category: Sulfotransferase]]

OCA: Protected "4p05" [edit=sysop:move=sysop]

OCA — Mon, 03 Mar 2014 16:57:39 GMT

Protected "4p05" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:57, 3 March 2014

OCA: New page: '''Unreleased structure''' The entry 4p05 is ON HOLD Authors: Malojcic, G., Owen, R.L., Glockshuber, R. Description: Bacterial arylsulfate sulfotransferase (ASST) H436N mutant with 4-n...

OCA — Mon, 03 Mar 2014 16:57:38 GMT

New page: '''Unreleased structure''' The entry 4p05 is ON HOLD Authors: Malojcic, G., Owen, R.L., Glockshuber, R. Description: Bacterial arylsulfate sulfotransferase (ASST) H436N mutant with 4-n...

New page

'''Unreleased structure'''

The entry 4p05 is ON HOLD

Authors: Malojcic, G., Owen, R.L., Glockshuber, R.

Description: Bacterial arylsulfate sulfotransferase (ASST) H436N mutant with 4-nitrophenyl sulfate (PNS) in the active site