4p1b - Revision history

OCA at 07:08, 27 September 2023

OCA — Wed, 27 Sep 2023 07:08:45 GMT

←Older revision		Revision as of 07:08, 27 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4p1b]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_mendocina Pseudomonas mendocina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P1B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4P1B FirstGlance]. <br>		<table><tr><td colspan='2'>[[4p1b]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_mendocina Pseudomonas mendocina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P1B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4P1B FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.05Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4p1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p1b OCA], [https://pdbe.org/4p1b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4p1b RCSB], [https://www.ebi.ac.uk/pdbsum/4p1b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4p1b ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4p1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p1b OCA], [https://pdbe.org/4p1b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4p1b RCSB], [https://www.ebi.ac.uk/pdbsum/4p1b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4p1b ProSAT]</span></td></tr>
	</table>		</table>

OCA at 12:36, 1 February 2023

OCA — Wed, 01 Feb 2023 12:36:49 GMT

←Older revision		Revision as of 12:36, 1 February 2023
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	<StructureSection load='4p1b' size='340' side='right'caption='[[4p1b]], [[Resolution\|resolution]] 2.05Å' scene=''>		<StructureSection load='4p1b' size='340' side='right'caption='[[4p1b]], [[Resolution\|resolution]] 2.05Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4p1b]] is a 8 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_25411 Atcc 25411~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P1B OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4P1B FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4p1b]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_mendocina Pseudomonas mendocina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P1B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4P1B FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4p1c\|4p1c]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4p1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p1b OCA], [https://pdbe.org/4p1b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4p1b RCSB], [https://www.ebi.ac.uk/pdbsum/4p1b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4p1b ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">tmoA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300 ATCC 25411]), tmoE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300 ATCC 25411]), tmoB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300 ATCC 25411]), tmoC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300 ATCC 25411])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4p1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p1b OCA], [~~http~~://pdbe.org/4p1b PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4p1b RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4p1b PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4p1b ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http://www.uniprot.org/uniprot/TMOC_PSEME TMOC_PSEME]] Probable electron transfer from NADPH, via FAD and the 2Fe-2S center, to the oxygenase activity site of the enzyme. [[http~~://www.uniprot.org/uniprot/TMOA_PSEME TMOA_PSEME]] Hydroxylase subunit of the multicomponent enzyme toluene-4-monooxygenase that hydroxylates toluene to form p-cresol.<ref>PMID:19290655</ref> <ref>PMID:19705873</ref> [[http://www.uniprot.org/uniprot/TMOB_PSEME TMOB_PSEME]] Subunit T4moB of the multicomponent enzyme toluene-4-monooxygenase that hydroxylates toluene to form p-cresol.<ref>PMID:19290655</ref> <ref>PMID:19705873</ref> [[http://www.uniprot.org/uniprot/TMOE_PSEME TMOE_PSEME]] Subunit of the multicomponent enzyme toluene-4-monooxygenase that hydroxylates toluene to form p-cresol.	+	[https://www.uniprot.org/uniprot/TMOA_PSEME TMOA_PSEME] Hydroxylase subunit of the multicomponent enzyme toluene-4-monooxygenase that hydroxylates toluene to form p-cresol.<ref>PMID:19290655</ref> <ref>PMID:19705873</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 25411]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Acheson, J F~~]]	+	[[Category: Pseudomonas mendocina]]
-	[[Category: ~~Fox, B G~~]]	+	[[Category: Acheson JF]]
-	[[Category: ~~Diiron enzyme complex]]~~	+	[[Category: Fox BG]]
-	~~[[Category: Electron-transfer complex]]~~	+
-	~~[[Category: Hydroxylase ferredoxin]]~~	+
-	~~[[Category: Iron-sulfur]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Oxygenase]]~~	+
-	~~[[Category: Reduction~~]]	+

OCA at 07:14, 27 November 2019

OCA — Wed, 27 Nov 2019 07:14:29 GMT

←Older revision		Revision as of 07:14, 27 November 2019
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	==CRYSTAL STRUCTURE OF THE TOLUENE 4-MONOOXYGENASE HYDROXYLASE-FERREDOXIN C7S E16C C84A C85A VARIANT ELECTRON-TRANSFER COMPLEX==		==CRYSTAL STRUCTURE OF THE TOLUENE 4-MONOOXYGENASE HYDROXYLASE-FERREDOXIN C7S E16C C84A C85A VARIANT ELECTRON-TRANSFER COMPLEX==
-	<StructureSection load='4p1b' size='340' side='right' caption='[[4p1b]], [[Resolution\|resolution]] 2.05Å' scene=''>	+	<StructureSection load='4p1b' size='340' side='right'caption='[[4p1b]], [[Resolution\|resolution]] 2.05Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4p1b]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_25411 Atcc 25411]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P1B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P1B FirstGlance]. <br>		<table><tr><td colspan='2'>[[4p1b]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_25411 Atcc 25411]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P1B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P1B FirstGlance]. <br>
Line 20:		Line 20:
	</div>		</div>
	<div class="pdbe-citations 4p1b" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4p1b" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Monooxygenase 3D structures\|Monooxygenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 25:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 25411]]		[[Category: Atcc 25411]]
		+	[[Category: Large Structures]]
	[[Category: Acheson, J F]]		[[Category: Acheson, J F]]
	[[Category: Fox, B G]]		[[Category: Fox, B G]]

OCA at 08:32, 22 November 2017

OCA — Wed, 22 Nov 2017 08:32:51 GMT

←Older revision		Revision as of 08:32, 22 November 2017
Line 3:		Line 3:
	<StructureSection load='4p1b' size='340' side='right' caption='[[4p1b]], [[Resolution\|resolution]] 2.05Å' scene=''>		<StructureSection load='4p1b' size='340' side='right' caption='[[4p1b]], [[Resolution\|resolution]] 2.05Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4p1b]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P1B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P1B FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4p1b]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_25411 Atcc 25411]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P1B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P1B FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4p1c\|4p1c]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">tmoA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300 ATCC 25411]), tmoE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300 ATCC 25411]), tmoB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300 ATCC 25411]), tmoC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300 ATCC 25411])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p1b OCA], [http://pdbe.org/4p1b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4p1b RCSB], [http://www.ebi.ac.uk/pdbsum/4p1b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4p1b ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p1b OCA], [http://pdbe.org/4p1b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4p1b RCSB], [http://www.ebi.ac.uk/pdbsum/4p1b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4p1b ProSAT]</span></td></tr>
	</table>		</table>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 25411]]
	[[Category: Acheson, J F]]		[[Category: Acheson, J F]]
	[[Category: Fox, B G]]		[[Category: Fox, B G]]

OCA at 07:32, 5 August 2016

OCA — Fri, 05 Aug 2016 07:32:38 GMT

←Older revision		Revision as of 07:32, 5 August 2016
Line 1:		Line 1:
		+
	==CRYSTAL STRUCTURE OF THE TOLUENE 4-MONOOXYGENASE HYDROXYLASE-FERREDOXIN C7S E16C C84A C85A VARIANT ELECTRON-TRANSFER COMPLEX==		==CRYSTAL STRUCTURE OF THE TOLUENE 4-MONOOXYGENASE HYDROXYLASE-FERREDOXIN C7S E16C C84A C85A VARIANT ELECTRON-TRANSFER COMPLEX==
	<StructureSection load='4p1b' size='340' side='right' caption='[[4p1b]], [[Resolution\|resolution]] 2.05Å' scene=''>		<StructureSection load='4p1b' size='340' side='right' caption='[[4p1b]], [[Resolution\|resolution]] 2.05Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4p1b]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P1B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P1B FirstGlance]. <br>		<table><tr><td colspan='2'>[[4p1b]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P1B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P1B FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p1b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p1b RCSB], [http://www.ebi.ac.uk/pdbsum/4p1b PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p1b OCA], [http://pdbe.org/4p1b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4p1b RCSB], [http://www.ebi.ac.uk/pdbsum/4p1b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4p1b ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4p1b" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 00:18, 25 December 2014

OCA — Thu, 25 Dec 2014 00:18:37 GMT

←Older revision		Revision as of 00:18, 25 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p1b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p1b RCSB], [http://www.ebi.ac.uk/pdbsum/4p1b PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p1b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p1b RCSB], [http://www.ebi.ac.uk/pdbsum/4p1b PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/TMOC_PSEME TMOC_PSEME]] Probable electron transfer from NADPH, via FAD and the 2Fe-2S center, to the oxygenase activity site of the enzyme. [[http://www.uniprot.org/uniprot/TMOA_PSEME TMOA_PSEME]] Hydroxylase subunit of the multicomponent enzyme toluene-4-monooxygenase that hydroxylates toluene to form p-cresol.<ref>PMID:19290655</ref> <ref>PMID:19705873</ref> [[http://www.uniprot.org/uniprot/TMOB_PSEME TMOB_PSEME]] Subunit T4moB of the multicomponent enzyme toluene-4-monooxygenase that hydroxylates toluene to form p-cresol.<ref>PMID:19290655</ref> <ref>PMID:19705873</ref> [[http://www.uniprot.org/uniprot/TMOE_PSEME TMOE_PSEME]] Subunit of the multicomponent enzyme toluene-4-monooxygenase that hydroxylates toluene to form p-cresol.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Acheson, J F.]]	+	[[Category: Acheson, J F]]
-	[[Category: Fox, B G.]]	+	[[Category: Fox, B G]]
	[[Category: Diiron enzyme complex]]		[[Category: Diiron enzyme complex]]
	[[Category: Electron-transfer complex]]		[[Category: Electron-transfer complex]]

OCA at 05:56, 8 October 2014

OCA — Wed, 08 Oct 2014 05:56:27 GMT

←Older revision		Revision as of 05:56, 8 October 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4p1b]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P1B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P1B FirstGlance]. <br>		<table><tr><td colspan='2'>[[4p1b]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P1B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P1B FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p1b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p1b RCSB], [http://www.ebi.ac.uk/pdbsum/4p1b PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p1b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p1b RCSB], [http://www.ebi.ac.uk/pdbsum/4p1b PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Productive biomolecular recognition requires exquisite control of affinity and specificity. Accordingly, nature has devised many strategies to achieve proper binding interactions. Bacterial multicomponent monooxygenases provide a fascinating example, where a diiron hydroxylase must reversibly interact with both ferredoxin and catalytic effector in order to achieve electron transfer and O2 activation during catalysis. Because these two accessory proteins have distinct structures, and because the hydroxylase-effector complex covers the entire surface closest to the hydroxylase diiron centre, how ferredoxin binds to the hydroxylase has been unclear. Here we present high-resolution structures of toluene 4-monooxygenase hydroxylase complexed with its electron transfer ferredoxin and compare them with the hydroxylase-effector structure. These structures reveal that ferredoxin or effector protein binding produce different arrangements of conserved residues and customized interfaces on the hydroxylase in order to achieve different aspects of catalysis.
		+
		+	Structural basis for biomolecular recognition in overlapping binding sites in a diiron enzyme system.,Acheson JF, Bailey LJ, Elsen NL, Fox BG Nat Commun. 2014 Sep 24;5:5009. doi: 10.1038/ncomms6009. PMID:25248368<ref>PMID:25248368</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 00:25, 2 October 2014

OCA — Thu, 02 Oct 2014 00:25:24 GMT

←Older revision		Revision as of 00:25, 2 October 2014
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==CRYSTAL STRUCTURE OF THE TOLUENE 4-MONOOXYGENASE HYDROXYLASE-FERREDOXIN C7S E16C C84A C85A VARIANT ELECTRON-TRANSFER COMPLEX==
-		+	<StructureSection load='4p1b' size='340' side='right' caption='[[4p1b]], [[Resolution\|resolution]] 2.05Å' scene=''>
-	~~The entry~~ 4p1b is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4p1b]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P1B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P1B FirstGlance]. <br>
-	~~Authors~~: Acheson, J.F., Fox, B.G.	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene><br>
-		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p1b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p1b RCSB], [http://www.ebi.ac.uk/pdbsum/4p1b PDBsum]</span></td></tr>
-	~~Description~~: ~~CRYSTAL STRUCTURE OF THE TOLUENE 4~~-~~MONOOXYGENASE HYDROXYLASE~~-~~FERREDOXIN C7S E16C C84A C85A VARIANT ELECTRON-TRANSFER COMPLEX~~	+	<table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Acheson, J F.]]
		+	[[Category: Fox, B G.]]
		+	[[Category: Diiron enzyme complex]]
		+	[[Category: Electron-transfer complex]]
		+	[[Category: Hydroxylase ferredoxin]]
		+	[[Category: Iron-sulfur]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Oxygenase]]
		+	[[Category: Reduction]]

OCA at 07:06, 14 May 2014

OCA — Wed, 14 May 2014 07:06:02 GMT

←Older revision		Revision as of 07:06, 14 May 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4p1b is ON HOLD	+	The entry 4p1b is ON HOLD until Paper Publication

	Authors: Acheson, J.F., Fox, B.G.		Authors: Acheson, J.F., Fox, B.G.

	Description: CRYSTAL STRUCTURE OF THE TOLUENE 4-MONOOXYGENASE HYDROXYLASE-FERREDOXIN C7S E16C C84A C85A VARIANT ELECTRON-TRANSFER COMPLEX		Description: CRYSTAL STRUCTURE OF THE TOLUENE 4-MONOOXYGENASE HYDROXYLASE-FERREDOXIN C7S E16C C84A C85A VARIANT ELECTRON-TRANSFER COMPLEX

OCA: Protected "4p1b" [edit=sysop:move=sysop]

OCA — Wed, 12 Mar 2014 12:27:58 GMT

Protected "4p1b" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:27, 12 March 2014