4pbq - Revision history

OCA at 00:42, 28 December 2023

OCA — Thu, 28 Dec 2023 00:42:28 GMT

←Older revision		Revision as of 00:42, 28 December 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4pbq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae_RdAW Haemophilus influenzae RdAW]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PBQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PBQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[4pbq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae_RdAW Haemophilus influenzae RdAW]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PBQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PBQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2UF:L-GULONATE'>2UF</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.65Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2UF:L-GULONATE'>2UF</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pbq OCA], [https://pdbe.org/4pbq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pbq RCSB], [https://www.ebi.ac.uk/pdbsum/4pbq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pbq ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pbq OCA], [https://pdbe.org/4pbq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pbq RCSB], [https://www.ebi.ac.uk/pdbsum/4pbq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pbq ProSAT]</span></td></tr>
	</table>		</table>

OCA at 12:50, 1 February 2023

OCA — Wed, 01 Feb 2023 12:50:56 GMT

←Older revision		Revision as of 12:50, 1 February 2023
Line 3:		Line 3:
	<StructureSection load='4pbq' size='340' side='right'caption='[[4pbq]], [[Resolution\|resolution]] 1.65Å' scene=''>		<StructureSection load='4pbq' size='340' side='right'caption='[[4pbq]], [[Resolution\|resolution]] 1.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4pbq]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Haemophilus_influenzae_rdaw~~ Haemophilus influenzae ~~rdaw~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PBQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4PBQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4pbq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae_RdAW Haemophilus influenzae RdAW]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PBQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PBQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2UF:L-GULONATE'>2UF</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=~~PEG~~:~~DI(HYDROXYETHYL)ETHER~~'>~~PEG~~</scene>, <scene name='pdbligand=~~SO4~~:~~SULFATE+ION~~'>~~SO4~~</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2UF:L-GULONATE'>2UF</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=~~MSE~~:~~SELENOMETHIONINE~~'>~~MSE~~</scene>~~</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pbq OCA], [https://pdbe.org/4pbq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pbq RCSB], [https://www.ebi.ac.uk/pdbsum/4pbq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pbq ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HICG_00826 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=656912 Haemophilus influenzae RdAW])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4pbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pbq OCA], [~~http~~://pdbe.org/4pbq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4pbq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4pbq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4pbq ProSAT]</span></td></tr>	+
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 22:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Haemophilus influenzae ~~rdaw~~]]	+	[[Category: Haemophilus influenzae RdAW]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Almo, S C~~]]	+	[[Category: Al Obaidi NF]]
-	[[Category: ~~Attonito, J D~~]]	+	[[Category: Almo SC]]
-	[[Category: ~~Chowdhury, S~~]]	+	[[Category: Attonito JD]]
-	[[Category: ~~EFI, Enzyme Function Initiative~~]]	+	[[Category: Chowdhury S]]
-	[[Category: Evans, B]]	+	[[Category: Evans B]]
-	[[Category: Gerlt~~, J A]]~~	+	[[Category: Gerlt JA]]
-	~~[[Category: Glenn, A Scott~~]]	+	[[Category: Hillerich B]]
-	[[Category: Hillerich, B]]	+	[[Category: Love J]]
-	[[Category: Love, J]]	+	[[Category: Morisco LL]]
-	[[Category: Morisco~~, L L~~]]	+	[[Category: Scott Glenn A]]
-	[[Category: ~~Obaidi, N F.Al~~]]	+	[[Category: Seidel RD]]
-	[[Category: Seidel~~, R D~~]]	+	[[Category: Stead M]]
-	[[Category: Stead, M]]	+	[[Category: Vetting MW]]
-	[[Category: Vetting~~, M W~~]]	+	[[Category: Wasserman SR]]
-	[[Category: Wasserman~~, S R~~]]	+	[[Category: Whalen KL]]
-	[[Category: Whalen~~, K L]]~~	+
-	~~[[Category: Efi]]~~	+
-	~~[[Category: Enzyme function initiative]]~~	+
-	~~[[Category: Solute-binding protein]]~~	+
-	~~[[Category: Structural genomic]]~~	+
-	~~[[Category: Trap periplasmic solute binding family~~]]	+

OCA at 10:11, 25 December 2019

OCA — Wed, 25 Dec 2019 10:11:02 GMT

←Older revision		Revision as of 10:11, 25 December 2019
Line 1:		Line 1:

	==CRYSTAL STRUCTURE OF A TRAP PERIPLASMIC SOLUTE BINDING PROTEIN FROM HAEMOPHILUS INFLUENZAE RdAW (HICG_00826, TARGET EFI-510123) WITH BOUND L-GULONATE==		==CRYSTAL STRUCTURE OF A TRAP PERIPLASMIC SOLUTE BINDING PROTEIN FROM HAEMOPHILUS INFLUENZAE RdAW (HICG_00826, TARGET EFI-510123) WITH BOUND L-GULONATE==
-	<StructureSection load='4pbq' size='340' side='right' caption='[[4pbq]], [[Resolution\|resolution]] 1.65Å' scene=''>	+	<StructureSection load='4pbq' size='340' side='right'caption='[[4pbq]], [[Resolution\|resolution]] 1.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4pbq]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae_rdaw Haemophilus influenzae rdaw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PBQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PBQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[4pbq]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae_rdaw Haemophilus influenzae rdaw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PBQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PBQ FirstGlance]. <br>
Line 23:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Haemophilus influenzae rdaw]]		[[Category: Haemophilus influenzae rdaw]]
		+	[[Category: Large Structures]]
	[[Category: Almo, S C]]		[[Category: Almo, S C]]
	[[Category: Attonito, J D]]		[[Category: Attonito, J D]]

OCA at 11:58, 6 November 2017

OCA — Mon, 06 Nov 2017 11:58:30 GMT

←Older revision		Revision as of 11:58, 6 November 2017
Line 1:		Line 1:
		+
	==CRYSTAL STRUCTURE OF A TRAP PERIPLASMIC SOLUTE BINDING PROTEIN FROM HAEMOPHILUS INFLUENZAE RdAW (HICG_00826, TARGET EFI-510123) WITH BOUND L-GULONATE==		==CRYSTAL STRUCTURE OF A TRAP PERIPLASMIC SOLUTE BINDING PROTEIN FROM HAEMOPHILUS INFLUENZAE RdAW (HICG_00826, TARGET EFI-510123) WITH BOUND L-GULONATE==
	<StructureSection load='4pbq' size='340' side='right' caption='[[4pbq]], [[Resolution\|resolution]] 1.65Å' scene=''>		<StructureSection load='4pbq' size='340' side='right' caption='[[4pbq]], [[Resolution\|resolution]] 1.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4pbq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PBQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PBQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4pbq]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae_rdaw Haemophilus influenzae rdaw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PBQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PBQ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2UF:L-GULONATE'>2UF</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2UF:L-GULONATE'>2UF</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pbq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pbq RCSB], [http://www.ebi.ac.uk/pdbsum/4pbq PDBsum]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HICG_00826 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=656912 Haemophilus influenzae RdAW])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pbq OCA], [http://pdbe.org/4pbq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pbq RCSB], [http://www.ebi.ac.uk/pdbsum/4pbq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pbq ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4pbq" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Haemophilus influenzae rdaw]]
	[[Category: Almo, S C]]		[[Category: Almo, S C]]
	[[Category: Attonito, J D]]		[[Category: Attonito, J D]]

OCA at 08:16, 25 February 2015

OCA — Wed, 25 Feb 2015 08:16:46 GMT

←Older revision		Revision as of 08:16, 25 February 2015
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pbq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pbq RCSB], [http://www.ebi.ac.uk/pdbsum/4pbq PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pbq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pbq RCSB], [http://www.ebi.ac.uk/pdbsum/4pbq PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The rate at which genome sequencing data is accruing demands enhanced methods for functional annotation and metabolism discovery. Solute binding proteins (SBPs) facilitate the transport of the first reactant in a metabolic pathway, thereby constraining the regions of chemical space and the chemistries that must be considered for pathway reconstruction. We describe high-throughput protein production and differential scanning fluorimetry platforms, which enabled the screening of 158 SBPs against a 189 component library specifically tailored for this class of proteins. Like all screening efforts, this approach is limited by the practical constraints imposed by construction of the library, i.e., we can study only those metabolites that are known to exist and which can be made in sufficient quantities for experimentation. To move beyond these inherent limitations, we illustrate the promise of crystallographic- and mass spectrometric-based approaches for the unbiased use of entire metabolomes as screening libraries. Together, our approaches identified 40 new SBP ligands, generated experiment-based annotations for 2084 SBPs in 71 isofunctional clusters, and defined numerous metabolic pathways, including novel catabolic pathways for the utilization of ethanolamine as sole nitrogen source and the use of d-Ala-d-Ala as sole carbon source. These efforts begin to define an integrated strategy for realizing the full value of amassing genome sequence data.
		+
		+	Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.,Vetting MW, Al-Obaidi N, Zhao S, San Francisco B, Kim J, Wichelecki DJ, Bouvier JT, Solbiati JO, Vu H, Zhang X, Rodionov DA, Love JD, Hillerich BS, Seidel RD, Quinn RJ, Osterman AL, Cronan JE, Jacobson MP, Gerlt JA, Almo SC Biochemistry. 2015 Jan 27;54(3):909-31. doi: 10.1021/bi501388y. Epub 2015 Jan 16. PMID:25540822<ref>PMID:25540822</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 09:48, 5 January 2015

OCA — Mon, 05 Jan 2015 09:48:10 GMT

←Older revision		Revision as of 09:48, 5 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4pbq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PBQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PBQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[4pbq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PBQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PBQ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2UF:L-GULONATE'>2UF</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2UF:L-GULONATE'>2UF</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pbq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pbq RCSB], [http://www.ebi.ac.uk/pdbsum/4pbq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pbq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pbq RCSB], [http://www.ebi.ac.uk/pdbsum/4pbq PDBsum]</span></td></tr>
-	<table>	+	</table>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Almo, S C.]]	+	[[Category: Almo, S C]]
-	[[Category: Attonito, J D.]]	+	[[Category: Attonito, J D]]
-	[[Category: Chowdhury, S.]]	+	[[Category: Chowdhury, S]]
-	[[Category: EFI, Enzyme Function Initiative.]]	+	[[Category: EFI, Enzyme Function Initiative]]
-	[[Category: Evans, B.]]	+	[[Category: Evans, B]]
-	[[Category: Gerlt, J A.]]	+	[[Category: Gerlt, J A]]
-	[[Category: Glenn, A Scott.]]	+	[[Category: Glenn, A Scott]]
-	[[Category: Hillerich, B.]]	+	[[Category: Hillerich, B]]
-	[[Category: Love, J.]]	+	[[Category: Love, J]]
-	[[Category: Morisco, L L.]]	+	[[Category: Morisco, L L]]
-	[[Category: Obaidi, N F.Al.]]	+	[[Category: Obaidi, N F.Al]]
-	[[Category: Seidel, R D.]]	+	[[Category: Seidel, R D]]
-	[[Category: Stead, M.]]	+	[[Category: Stead, M]]
-	[[Category: Vetting, M W.]]	+	[[Category: Vetting, M W]]
-	[[Category: Wasserman, S R.]]	+	[[Category: Wasserman, S R]]
-	[[Category: Whalen, K L.]]	+	[[Category: Whalen, K L]]
	[[Category: Efi]]		[[Category: Efi]]
	[[Category: Enzyme function initiative]]		[[Category: Enzyme function initiative]]

OCA at 07:10, 11 June 2014

OCA — Wed, 11 Jun 2014 07:10:32 GMT

←Older revision		Revision as of 07:10, 11 June 2014
Line 2:		Line 2:
	<StructureSection load='4pbq' size='340' side='right' caption='[[4pbq]], [[Resolution\|resolution]] 1.65Å' scene=''>		<StructureSection load='4pbq' size='340' side='right' caption='[[4pbq]], [[Resolution\|resolution]] 1.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4pbq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PBQ OCA]. <br>	+	<table><tr><td colspan='2'>[[4pbq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PBQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PBQ FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2UF:L-GULONATE'>2UF</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>		</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2UF:L-GULONATE'>2UF</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pbq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pbq RCSB], [http://www.ebi.ac.uk/pdbsum/4pbq PDBsum]</span></td></tr>		<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pbq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pbq RCSB], [http://www.ebi.ac.uk/pdbsum/4pbq PDBsum]</span></td></tr>
	<table>		<table>

OCA at 07:36, 14 May 2014

OCA — Wed, 14 May 2014 07:36:05 GMT

←Older revision		Revision as of 07:36, 14 May 2014
Line 8:		Line 8:
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pbq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pbq RCSB], [http://www.ebi.ac.uk/pdbsum/4pbq PDBsum]</span></td></tr>		<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pbq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pbq RCSB], [http://www.ebi.ac.uk/pdbsum/4pbq PDBsum]</span></td></tr>
	<table>		<table>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 06:53, 14 May 2014

OCA — Wed, 14 May 2014 06:53:50 GMT

←Older revision		Revision as of 06:53, 14 May 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4pbq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PBQ OCA]. <br>		<table><tr><td colspan='2'>[[4pbq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PBQ OCA]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG~~</scene>, <scene name='pdbligand=REL:D-GLUCURONIC+ACID'>REL~~</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2UF:L-GULONATE'>2UF</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>		<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>

OCA at 08:23, 7 May 2014

OCA — Wed, 07 May 2014 08:23:45 GMT

←Older revision		Revision as of 08:23, 7 May 2014
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==CRYSTAL STRUCTURE OF A TRAP PERIPLASMIC SOLUTE BINDING PROTEIN FROM HAEMOPHILUS INFLUENZAE RdAW (HICG_00826, TARGET EFI-510123) WITH BOUND L-GULONATE==
-		+	<StructureSection load='4pbq' size='340' side='right' caption='[[4pbq]], [[Resolution\|resolution]] 1.65Å' scene=''>
-	~~The entry~~ 4pbq is ~~ON HOLD~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4pbq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PBQ OCA]. <br>
-	~~Authors~~: ~~Vetting~~, M.W., ~~Al Obaidi, N~~.F., ~~Morisco, L~~.L., ~~Wasserman, S~~.R., ~~Stead, M~~., Attonito, J.D.~~, Scott Glenn, A.,~~ Chowdhury, S., Evans, B., Hillerich, B., Love, J., Seidel, R.D., ~~Whalen, K.L~~., ~~Gerlt, J~~.~~A., Almo~~, S.C., ~~Enzyme Function Initiative (EFI)~~	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=REL:D-GLUCURONIC+ACID'>REL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	~~Description~~: ~~CRYSTAL STRUCTURE OF A TRAP PERIPLASMIC SOLUTE BINDING PROTEIN FROM HAEMOPHILUS INFLUENZAE RdAW (HICG_00826, TARGET EFI~~-~~510123) WITH BOUND L-GULONATE~~	+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pbq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pbq RCSB], [http://www.ebi.ac.uk/pdbsum/4pbq PDBsum]</span></td></tr>
		+	<table>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Almo, S C.]]
		+	[[Category: Attonito, J D.]]
		+	[[Category: Chowdhury, S.]]
		+	[[Category: EFI, Enzyme Function Initiative.]]
		+	[[Category: Evans, B.]]
		+	[[Category: Gerlt, J A.]]
		+	[[Category: Glenn, A Scott.]]
		+	[[Category: Hillerich, B.]]
		+	[[Category: Love, J.]]
		+	[[Category: Morisco, L L.]]
		+	[[Category: Obaidi, N F.Al.]]
		+	[[Category: Seidel, R D.]]
		+	[[Category: Stead, M.]]
		+	[[Category: Vetting, M W.]]
		+	[[Category: Wasserman, S R.]]
		+	[[Category: Whalen, K L.]]
		+	[[Category: Efi]]
		+	[[Category: Enzyme function initiative]]
		+	[[Category: Solute-binding protein]]
		+	[[Category: Structural genomic]]
		+	[[Category: Trap periplasmic solute binding family]]