4pgy - Revision history

OCA at 00:43, 28 December 2023

OCA — Thu, 28 Dec 2023 00:43:46 GMT

←Older revision		Revision as of 00:43, 28 December 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4pgy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PGY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PGY FirstGlance]. <br>		<table><tr><td colspan='2'>[[4pgy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PGY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PGY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.26Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pgy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pgy OCA], [https://pdbe.org/4pgy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pgy RCSB], [https://www.ebi.ac.uk/pdbsum/4pgy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pgy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pgy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pgy OCA], [https://pdbe.org/4pgy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pgy RCSB], [https://www.ebi.ac.uk/pdbsum/4pgy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pgy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/DPOLB_HUMAN DPOLB_HUMAN] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<ref>PMID:9207062</ref> <ref>PMID:9572863</ref> <ref>PMID:11805079</ref> <ref>PMID:21362556</ref>		[https://www.uniprot.org/uniprot/DPOLB_HUMAN DPOLB_HUMAN] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<ref>PMID:9207062</ref> <ref>PMID:9572863</ref> <ref>PMID:11805079</ref> <ref>PMID:21362556</ref>
		+
		+	==See Also==
		+	*[[DNA polymerase 3D structures\|DNA polymerase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:01, 1 February 2023

OCA — Wed, 01 Feb 2023 13:01:39 GMT

←Older revision		Revision as of 13:01, 1 February 2023
Line 3:		Line 3:
	<StructureSection load='4pgy' size='340' side='right'caption='[[4pgy]], [[Resolution\|resolution]] 2.26Å' scene=''>		<StructureSection load='4pgy' size='340' side='right'caption='[[4pgy]], [[Resolution\|resolution]] 2.26Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4pgy]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PGY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=4PGY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4pgy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PGY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PGY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">POLB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pgy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pgy OCA], [https://pdbe.org/4pgy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pgy RCSB], [https://www.ebi.ac.uk/pdbsum/4pgy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pgy ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=4pgy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pgy OCA], [~~http~~://pdbe.org/4pgy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4pgy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4pgy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4pgy ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/DPOLB_HUMAN DPOLB_HUMAN]] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<ref>PMID:9207062</ref> <ref>PMID:9572863</ref> <ref>PMID:11805079</ref> <ref>PMID:21362556</ref>	+	[https://www.uniprot.org/uniprot/DPOLB_HUMAN DPOLB_HUMAN] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<ref>PMID:9207062</ref> <ref>PMID:9572863</ref> <ref>PMID:11805079</ref> <ref>PMID:21362556</ref>
-		+
-	~~==See Also==~~	+
-	*[[DNA polymerase 3D structures\|DNA polymerase 3D structures]]	+
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Koag, M C~~]]	+	[[Category: Synthetic construct]]
-	[[Category: ~~Lee, S~~]]	+	[[Category: Koag MC]]
-	[[Category: ~~Human dna polymerase beta]]~~	+	[[Category: Lee S]]
-	~~[[Category: Lyase-dna complex]]~~	+
-	~~[[Category: Nucleotidyl transfer]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 08:15, 20 January 2021

OCA — Wed, 20 Jan 2021 08:15:54 GMT

←Older revision		Revision as of 08:15, 20 January 2021
Line 3:		Line 3:
	<StructureSection load='4pgy' size='340' side='right'caption='[[4pgy]], [[Resolution\|resolution]] 2.26Å' scene=''>		<StructureSection load='4pgy' size='340' side='right'caption='[[4pgy]], [[Resolution\|resolution]] 2.26Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4pgy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PGY OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4PGY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4pgy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PGY OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4PGY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">POLB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">POLB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4pgy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pgy OCA], [http://pdbe.org/4pgy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pgy RCSB], [http://www.ebi.ac.uk/pdbsum/4pgy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pgy ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4pgy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pgy OCA], [http://pdbe.org/4pgy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pgy RCSB], [http://www.ebi.ac.uk/pdbsum/4pgy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pgy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 08:22, 18 December 2019

OCA — Wed, 18 Dec 2019 08:22:02 GMT

←Older revision		Revision as of 08:22, 18 December 2019
Line 1:		Line 1:

	==Structure of human DNA polymerase beta complexed with a nicked DNA containing a GT at N-1 position and GC at N position==		==Structure of human DNA polymerase beta complexed with a nicked DNA containing a GT at N-1 position and GC at N position==
-	<StructureSection load='4pgy' size='340' side='right' caption='[[4pgy]], [[Resolution\|resolution]] 2.26Å' scene=''>	+	<StructureSection load='4pgy' size='340' side='right'caption='[[4pgy]], [[Resolution\|resolution]] 2.26Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4pgy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PGY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PGY FirstGlance]. <br>		<table><tr><td colspan='2'>[[4pgy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PGY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PGY FirstGlance]. <br>
Line 10:		Line 10:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/DPOLB_HUMAN DPOLB_HUMAN]] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<ref>PMID:9207062</ref> <ref>PMID:9572863</ref> <ref>PMID:11805079</ref> <ref>PMID:21362556</ref>		[[http://www.uniprot.org/uniprot/DPOLB_HUMAN DPOLB_HUMAN]] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<ref>PMID:9207062</ref> <ref>PMID:9572863</ref> <ref>PMID:11805079</ref> <ref>PMID:21362556</ref>
		+
		+	==See Also==
		+	*[[DNA polymerase 3D structures\|DNA polymerase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 15:		Line 18:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Koag, M C]]		[[Category: Koag, M C]]
	[[Category: Lee, S]]		[[Category: Lee, S]]

OCA at 14:52, 15 November 2017

OCA — Wed, 15 Nov 2017 14:52:10 GMT

←Older revision		Revision as of 14:52, 15 November 2017
Line 3:		Line 3:
	<StructureSection load='4pgy' size='340' side='right' caption='[[4pgy]], [[Resolution\|resolution]] 2.26Å' scene=''>		<StructureSection load='4pgy' size='340' side='right' caption='[[4pgy]], [[Resolution\|resolution]] 2.26Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4pgy]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PGY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PGY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4pgy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PGY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PGY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">POLB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pgy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pgy OCA], [http://pdbe.org/4pgy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pgy RCSB], [http://www.ebi.ac.uk/pdbsum/4pgy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pgy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pgy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pgy OCA], [http://pdbe.org/4pgy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pgy RCSB], [http://www.ebi.ac.uk/pdbsum/4pgy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pgy ProSAT]</span></td></tr>
	</table>		</table>
Line 13:		Line 14:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Koag, M C]]		[[Category: Koag, M C]]
	[[Category: Lee, S]]		[[Category: Lee, S]]
	[[Category: Human dna polymerase beta]]		[[Category: Human dna polymerase beta]]
		+	[[Category: Lyase-dna complex]]
	[[Category: Nucleotidyl transfer]]		[[Category: Nucleotidyl transfer]]
		+	[[Category: Transferase]]

OCA at 17:37, 9 March 2017

OCA — Thu, 09 Mar 2017 17:37:44 GMT

←Older revision		Revision as of 17:37, 9 March 2017
Line 1:		Line 1:
		+
	==Structure of human DNA polymerase beta complexed with a nicked DNA containing a GT at N-1 position and GC at N position==		==Structure of human DNA polymerase beta complexed with a nicked DNA containing a GT at N-1 position and GC at N position==
	<StructureSection load='4pgy' size='340' side='right' caption='[[4pgy]], [[Resolution\|resolution]] 2.26Å' scene=''>		<StructureSection load='4pgy' size='340' side='right' caption='[[4pgy]], [[Resolution\|resolution]] 2.26Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4pgy]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PGY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PGY FirstGlance]. <br>		<table><tr><td colspan='2'>[[4pgy]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PGY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PGY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pgy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pgy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pgy RCSB], [http://www.ebi.ac.uk/pdbsum/4pgy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pgy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pgy OCA], [http://pdbe.org/4pgy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pgy RCSB], [http://www.ebi.ac.uk/pdbsum/4pgy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pgy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 12:57, 6 May 2015

OCA — Wed, 06 May 2015 12:57:30 GMT

←Older revision		Revision as of 12:57, 6 May 2015
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	==Structure of human DNA polymerase beta complexed with a nicked DNA containing a GT at N-1 position and GC at N position==
-		+	<StructureSection load='4pgy' size='340' side='right' caption='[[4pgy]], [[Resolution\|resolution]] 2.26Å' scene=''>
-	~~The entry 4pgy is ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4pgy]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PGY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PGY FirstGlance]. <br>
-	~~Authors: Koag, M.C., Lee, S.~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pgy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pgy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pgy RCSB], [http://www.ebi.ac.uk/pdbsum/4pgy PDBsum]</span></td></tr>
-	~~Description:~~ Structure of human DNA polymerase beta complexed with a nicked DNA containing a GT at N-1 position and GC at N position	+	</table>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	== Function ==
-	[[Category: Koag, M.C]]	+	[[http://www.uniprot.org/uniprot/DPOLB_HUMAN DPOLB_HUMAN]] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<ref>PMID:9207062</ref> <ref>PMID:9572863</ref> <ref>PMID:11805079</ref> <ref>PMID:21362556</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Koag, M C]]
	[[Category: Lee, S]]		[[Category: Lee, S]]
		+	[[Category: Human dna polymerase beta]]
		+	[[Category: Nucleotidyl transfer]]

OCA at 15:02, 24 December 2014

OCA — Wed, 24 Dec 2014 15:02:07 GMT

←Older revision		Revision as of 15:02, 24 December 2014
Line 6:		Line 6:

	Description: Structure of human DNA polymerase beta complexed with a nicked DNA containing a GT at N-1 position and GC at N position		Description: Structure of human DNA polymerase beta complexed with a nicked DNA containing a GT at N-1 position and GC at N position
		+	[[Category: Unreleased Structures]]
		+	[[Category: Koag, M.C]]
		+	[[Category: Lee, S]]

OCA at 09:40, 16 July 2014

OCA — Wed, 16 Jul 2014 09:40:49 GMT

←Older revision		Revision as of 09:40, 16 July 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4pgy is ON HOLD	+	The entry 4pgy is ON HOLD until Paper Publication

-	Authors: Koag, M.C, Lee, S	+	Authors: Koag, M.C., Lee, S.

	Description: Structure of human DNA polymerase beta complexed with a nicked DNA containing a GT at N-1 position and GC at N position		Description: Structure of human DNA polymerase beta complexed with a nicked DNA containing a GT at N-1 position and GC at N position

OCA: Protected "4pgy" [edit=sysop:move=sysop]

OCA — Wed, 14 May 2014 07:08:01 GMT

Protected "4pgy" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:08, 14 May 2014