4plm - Revision history

OCA at 00:45, 28 December 2023

OCA — Thu, 28 Dec 2023 00:45:24 GMT

←Older revision		Revision as of 00:45, 28 December 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4plm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PLM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PLM FirstGlance]. <br>		<table><tr><td colspan='2'>[[4plm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PLM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PLM FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.801Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4plm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4plm OCA], [https://pdbe.org/4plm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4plm RCSB], [https://www.ebi.ac.uk/pdbsum/4plm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4plm ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4plm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4plm OCA], [https://pdbe.org/4plm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4plm RCSB], [https://www.ebi.ac.uk/pdbsum/4plm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4plm ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:17, 8 February 2023

OCA — Wed, 08 Feb 2023 07:17:36 GMT

←Older revision		Revision as of 07:17, 8 February 2023
Line 3:		Line 3:
	<StructureSection load='4plm' size='340' side='right'caption='[[4plm]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='4plm' size='340' side='right'caption='[[4plm]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4plm]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Chick Chick~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PLM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4PLM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4plm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PLM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PLM FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4pln\|4pln]], [[4plo\|4plo]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4plm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4plm OCA], [https://pdbe.org/4plm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4plm RCSB], [https://www.ebi.ac.uk/pdbsum/4plm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4plm ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NTN1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4plm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4plm OCA], [~~http~~://pdbe.org/4plm PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4plm RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4plm PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4plm ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/NET1_CHICK NET1_CHICK]] Netrins control guidance of CNS commissural axons and peripheral motor axons. Promotes neurite outgrowth from commissural axons but acts as a chemorepellent for trochlear motor axons. These effects are mediated by distinct receptors.	+	[https://www.uniprot.org/uniprot/NET1_CHICK NET1_CHICK] Netrins control guidance of CNS commissural axons and peripheral motor axons. Promotes neurite outgrowth from commissural axons but acts as a chemorepellent for trochlear motor axons. These effects are mediated by distinct receptors.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 27:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Chick~~]]	+	[[Category: Gallus gallus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Nikolov~~, D B~~]]	+	[[Category: Nikolov DB]]
-	[[Category: Xu, K]]	+	[[Category: Xu K]]
-	~~[[Category: Cysteine rich]]~~	+
-	~~[[Category: Elongated]]~~	+
-	~~[[Category: Glycoprotein]]~~	+
-	~~[[Category: Protein binding~~]]	+

OCA at 08:35, 4 December 2019

OCA — Wed, 04 Dec 2019 08:35:32 GMT

←Older revision		Revision as of 08:35, 4 December 2019
Line 1:		Line 1:

	==Crystal Structure of Chicken Netrin-1 (LN-LE3)==		==Crystal Structure of Chicken Netrin-1 (LN-LE3)==
-	<StructureSection load='4plm' size='340' side='right' caption='[[4plm]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='4plm' size='340' side='right'caption='[[4plm]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4plm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PLM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PLM FirstGlance]. <br>		<table><tr><td colspan='2'>[[4plm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PLM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PLM FirstGlance]. <br>
Line 20:		Line 20:
	</div>		</div>
	<div class="pdbe-citations 4plm" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4plm" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Netrin\|Netrin]]
	== References ==		== References ==
	<references/>		<references/>
Line 25:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Chick]]		[[Category: Chick]]
		+	[[Category: Large Structures]]
	[[Category: Nikolov, D B]]		[[Category: Nikolov, D B]]
	[[Category: Xu, K]]		[[Category: Xu, K]]

OCA at 12:01, 6 November 2017

OCA — Mon, 06 Nov 2017 12:01:52 GMT

←Older revision		Revision as of 12:01, 6 November 2017
Line 3:		Line 3:
	<StructureSection load='4plm' size='340' side='right' caption='[[4plm]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='4plm' size='340' side='right' caption='[[4plm]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4plm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PLM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PLM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4plm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PLM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PLM FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4pln\|4pln]], [[4plo\|4plo]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4pln\|4pln]], [[4plo\|4plo]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NTN1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4plm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4plm OCA], [http://pdbe.org/4plm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4plm RCSB], [http://www.ebi.ac.uk/pdbsum/4plm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4plm ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4plm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4plm OCA], [http://pdbe.org/4plm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4plm RCSB], [http://www.ebi.ac.uk/pdbsum/4plm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4plm ProSAT]</span></td></tr>
	</table>		</table>
Line 19:		Line 20:
	</div>		</div>
	<div class="pdbe-citations 4plm" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4plm" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Netrin\|Netrin]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Chick]]
	[[Category: Nikolov, D B]]		[[Category: Nikolov, D B]]
	[[Category: Xu, K]]		[[Category: Xu, K]]

OCA at 17:17, 4 January 2017

OCA — Wed, 04 Jan 2017 17:17:06 GMT

←Older revision		Revision as of 17:17, 4 January 2017
Line 1:		Line 1:
		+
	==Crystal Structure of Chicken Netrin-1 (LN-LE3)==		==Crystal Structure of Chicken Netrin-1 (LN-LE3)==
	<StructureSection load='4plm' size='340' side='right' caption='[[4plm]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='4plm' size='340' side='right' caption='[[4plm]], [[Resolution\|resolution]] 2.80Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4pln\|4pln]], [[4plo\|4plo]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4pln\|4pln]], [[4plo\|4plo]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4plm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4plm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4plm RCSB], [http://www.ebi.ac.uk/pdbsum/4plm PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4plm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4plm OCA], [http://pdbe.org/4plm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4plm RCSB], [http://www.ebi.ac.uk/pdbsum/4plm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4plm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4plm" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Netrin\|Netrin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 14:56, 24 December 2014

OCA — Wed, 24 Dec 2014 14:56:18 GMT

←Older revision		Revision as of 14:56, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4plm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PLM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PLM FirstGlance]. <br>		<table><tr><td colspan='2'>[[4plm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PLM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PLM FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4pln\|4pln]], [[4plo\|4plo]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4pln\|4pln]], [[4plo\|4plo]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4plm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4plm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4plm RCSB], [http://www.ebi.ac.uk/pdbsum/4plm PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4plm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4plm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4plm RCSB], [http://www.ebi.ac.uk/pdbsum/4plm PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NET1_CHICK NET1_CHICK]] Netrins control guidance of CNS commissural axons and peripheral motor axons. Promotes neurite outgrowth from commissural axons but acts as a chemorepellent for trochlear motor axons. These effects are mediated by distinct receptors.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Nikolov, D B.]]	+	[[Category: Nikolov, D B]]
-	[[Category: Xu, K.]]	+	[[Category: Xu, K]]
	[[Category: Cysteine rich]]		[[Category: Cysteine rich]]
	[[Category: Elongated]]		[[Category: Elongated]]
	[[Category: Glycoprotein]]		[[Category: Glycoprotein]]
	[[Category: Protein binding]]		[[Category: Protein binding]]

OCA at 07:59, 18 June 2014

OCA — Wed, 18 Jun 2014 07:59:42 GMT

←Older revision		Revision as of 07:59, 18 June 2014
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal Structure of Chicken Netrin-1 (LN-LE3)==
		+	<StructureSection load='4plm' size='340' side='right' caption='[[4plm]], [[Resolution\|resolution]] 2.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4plm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PLM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PLM FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4pln\|4pln]], [[4plo\|4plo]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4plm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4plm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4plm RCSB], [http://www.ebi.ac.uk/pdbsum/4plm PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Netrins are secreted proteins that regulate axon guidance and neuronal migration. Deleted in colorectal cancer (DCC) is a well-established netrin-1 receptor mediating attractive responses. We provide evidence that its close relative neogenin is also a functional netrin-1 receptor that acts with DCC to mediate guidance in vivo. We determined the structures of a functional netrin-1 region, alone and in complexes with neogenin or DCC. Netrin-1 has a rigid elongated structure containing two receptor-binding sites at opposite ends through which it brings together receptor molecules. The ligand/receptor complexes reveal two distinct architectures: a 2:2 heterotetramer and a continuous ligand/receptor assembly. The differences result from different lengths of the linker connecting receptor domains fibronectin type III domain 4 (FN4) and FN5, which differs among DCC and neogenin splice variants, providing a basis for diverse signaling outcomes.

-	~~The entry 4plm is ON HOLD~~	+	Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism.,Xu K, Wu Z, Renier N, Antipenko A, Tzvetkova-Robev D, Xu Y, Minchenko M, Nardi-Dei V, Rajashankar KR, Himanen J, Tessier-Lavigne M, Nikolov DB Science. 2014 Jun 13;344(6189):1275-9. doi: 10.1126/science.1255149. Epub 2014, May 29. PMID:24876346<ref>PMID:24876346</ref>

-	~~Authors~~: Xu, K.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~:	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Nikolov, D B.]]
		+	[[Category: Xu, K.]]
		+	[[Category: Cysteine rich]]
		+	[[Category: Elongated]]
		+	[[Category: Glycoprotein]]
		+	[[Category: Protein binding]]

OCA: Protected "4plm" [edit=sysop:move=sysop]

OCA — Wed, 28 May 2014 08:15:56 GMT

Protected "4plm" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:15, 28 May 2014

OCA: New page: '''Unreleased structure''' The entry 4plm is ON HOLD Authors: Xu, K. Description:

OCA — Wed, 28 May 2014 08:15:54 GMT

New page: '''Unreleased structure''' The entry 4plm is ON HOLD Authors: Xu, K. Description:

New page

'''Unreleased structure'''

The entry 4plm is ON HOLD

Authors: Xu, K.

Description: