4ppr - Revision history

OCA at 17:20, 20 September 2023

OCA — Wed, 20 Sep 2023 17:20:20 GMT

←Older revision		Revision as of 17:20, 20 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4ppr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PPR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PPR FirstGlance]. <br>		<table><tr><td colspan='2'>[[4ppr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PPR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PPR FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MER:(4R,5S)-3-{[(3S,5S)-5-(DIMETHYLCARBAMOYL)PYRROLIDIN-3-YL]SULFANYL}-5-[(2S,3R)-3-HYDROXY-1-OXOBUTAN-2-YL]-4-METHYL-4,5-DIHYDRO-1H-PYRROLE-2-CARBOXYLIC+ACID'>MER</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MER:(4R,5S)-3-{[(3S,5S)-5-(DIMETHYLCARBAMOYL)PYRROLIDIN-3-YL]SULFANYL}-5-[(2S,3R)-3-HYDROXY-1-OXOBUTAN-2-YL]-4-METHYL-4,5-DIHYDRO-1H-PYRROLE-2-CARBOXYLIC+ACID'>MER</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ppr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ppr OCA], [https://pdbe.org/4ppr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ppr RCSB], [https://www.ebi.ac.uk/pdbsum/4ppr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ppr ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ppr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ppr OCA], [https://pdbe.org/4ppr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ppr RCSB], [https://www.ebi.ac.uk/pdbsum/4ppr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ppr ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:23, 8 February 2023

OCA — Wed, 08 Feb 2023 07:23:57 GMT

←Older revision		Revision as of 07:23, 8 February 2023
Line 3:		Line 3:
	<StructureSection load='4ppr' size='340' side='right'caption='[[4ppr]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4ppr' size='340' side='right'caption='[[4ppr]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ppr]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Myctu Myctu~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PPR OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4PPR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ppr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PPR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PPR FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MER:(4R,5S)-3-{[(3S,5S)-5-(DIMETHYLCARBAMOYL)PYRROLIDIN-3-YL]SULFANYL}-5-[(2S,3R)-3-HYDROXY-1-OXOBUTAN-2-YL]-4-METHYL-4,5-DIHYDRO-1H-PYRROLE-2-CARBOXYLIC+ACID'>MER</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MER:(4R,5S)-3-{[(3S,5S)-5-(DIMETHYLCARBAMOYL)PYRROLIDIN-3-YL]SULFANYL}-5-[(2S,3R)-3-HYDROXY-1-OXOBUTAN-2-YL]-4-METHYL-4,5-DIHYDRO-1H-PYRROLE-2-CARBOXYLIC+ACID'>MER</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4p0m\|4p0m]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ppr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ppr OCA], [https://pdbe.org/4ppr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ppr RCSB], [https://www.ebi.ac.uk/pdbsum/4ppr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ppr ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">rv3330, RVBD_3330 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ppr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ppr OCA], [~~http~~://pdbe.org/4ppr PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4ppr RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4ppr PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4ppr ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/DACB1_MYCTU DACB1_MYCTU] Probably cleaves the terminal D-Ala-D-Ala dipeptide of the peptidoglycan stem peptide (Probable). Shows weak D,D-carboxypeptidase activity in vitro (PubMed:22906310). Acts on the synthetic penta-peptide substrate Penta-DAP (L-Ala-gamma-D-Gln-DAP-D-Ala-D-Ala) (PubMed:22906310). The catalytic domain binds weakly to peptidoglycan in vitro (PubMed:25551456).<ref>PMID:22906310</ref> <ref>PMID:25551456</ref> <ref>PMID:22906310</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 4ppr" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4ppr" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Penicillin-binding protein 3D structures\|Penicillin-binding protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 23:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Myctu~~]]	+	[[Category: Mycobacterium tuberculosis H37Rv]]
-	[[Category: Alber, T]]	+	[[Category: Alber T]]
-	[[Category: Huizar~~, J P~~]]	+	[[Category: Huizar JP]]
-	[[Category: Mavrici, D]]	+	[[Category: Mavrici D]]
-	[[Category: Prigozhin~~, D M]]~~	+	[[Category: Prigozhin DM]]
-	~~[[Category: Structural genomic]]~~	+
-	~~[[Category: D-peptidase]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: National institute of allergy and infectious disease]]~~	+
-	~~[[Category: Niaid]]~~	+
-	~~[[Category: Penicillin-binding protein]]~~	+
-	~~[[Category: Peptidoglycan d]]~~	+
-	~~[[Category: Tbsgc~~]]	+

OCA at 07:15, 17 April 2019

OCA — Wed, 17 Apr 2019 07:15:59 GMT

←Older revision		Revision as of 07:15, 17 April 2019
Line 1:		Line 1:

	==Crystal structure of Mycobacterium tuberculosis D,D-peptidase Rv3330 in complex with meropenem==		==Crystal structure of Mycobacterium tuberculosis D,D-peptidase Rv3330 in complex with meropenem==
-	<StructureSection load='4ppr' size='340' side='right' caption='[[4ppr]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='4ppr' size='340' side='right'caption='[[4ppr]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ppr]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PPR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PPR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ppr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PPR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PPR FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MER:(4R,5S)-3-{[(3S,5S)-5-(DIMETHYLCARBAMOYL)PYRROLIDIN-3-YL]SULFANYL}-5-[(2S,3R)-3-HYDROXY-1-OXOBUTAN-2-YL]-4-METHYL-4,5-DIHYDRO-1H-PYRROLE-2-CARBOXYLIC+ACID'>MER</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MER:(4R,5S)-3-{[(3S,5S)-5-(DIMETHYLCARBAMOYL)PYRROLIDIN-3-YL]SULFANYL}-5-[(2S,3R)-3-HYDROXY-1-OXOBUTAN-2-YL]-4-METHYL-4,5-DIHYDRO-1H-PYRROLE-2-CARBOXYLIC+ACID'>MER</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4p0m\|4p0m]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4p0m\|4p0m]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">rv3330, RVBD_3330 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ppr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ppr OCA], [http://pdbe.org/4ppr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ppr RCSB], [http://www.ebi.ac.uk/pdbsum/4ppr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ppr ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ppr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ppr OCA], [http://pdbe.org/4ppr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ppr RCSB], [http://www.ebi.ac.uk/pdbsum/4ppr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ppr ProSAT]</span></td></tr>
	</table>		</table>
Line 21:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Myctu]]
	[[Category: Alber, T]]		[[Category: Alber, T]]
	[[Category: Huizar, J P]]		[[Category: Huizar, J P]]

OCA at 16:57, 4 January 2017

OCA — Wed, 04 Jan 2017 16:57:49 GMT

←Older revision		Revision as of 16:57, 4 January 2017
Line 1:		Line 1:
		+
	==Crystal structure of Mycobacterium tuberculosis D,D-peptidase Rv3330 in complex with meropenem==		==Crystal structure of Mycobacterium tuberculosis D,D-peptidase Rv3330 in complex with meropenem==
	<StructureSection load='4ppr' size='340' side='right' caption='[[4ppr]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4ppr' size='340' side='right' caption='[[4ppr]], [[Resolution\|resolution]] 2.00Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MER:(4R,5S)-3-{[(3S,5S)-5-(DIMETHYLCARBAMOYL)PYRROLIDIN-3-YL]SULFANYL}-5-[(2S,3R)-3-HYDROXY-1-OXOBUTAN-2-YL]-4-METHYL-4,5-DIHYDRO-1H-PYRROLE-2-CARBOXYLIC+ACID'>MER</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MER:(4R,5S)-3-{[(3S,5S)-5-(DIMETHYLCARBAMOYL)PYRROLIDIN-3-YL]SULFANYL}-5-[(2S,3R)-3-HYDROXY-1-OXOBUTAN-2-YL]-4-METHYL-4,5-DIHYDRO-1H-PYRROLE-2-CARBOXYLIC+ACID'>MER</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4p0m\|4p0m]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4p0m\|4p0m]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ppr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ppr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ppr RCSB], [http://www.ebi.ac.uk/pdbsum/4ppr PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ppr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ppr OCA], [http://pdbe.org/4ppr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ppr RCSB], [http://www.ebi.ac.uk/pdbsum/4ppr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ppr ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4ppr" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:19, 4 March 2015

OCA — Wed, 04 Mar 2015 11:19:01 GMT

←Older revision		Revision as of 11:19, 4 March 2015
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ppr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ppr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ppr RCSB], [http://www.ebi.ac.uk/pdbsum/4ppr PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ppr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ppr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ppr RCSB], [http://www.ebi.ac.uk/pdbsum/4ppr PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Beta-lactam antibiotics target penicillin-binding proteins including several enzyme classes essential for bacterial cell-wall homeostasis. To better understand the functional and inhibitor-binding specificities of penicillin-binding proteins from the pathogen, Mycobacterium tuberculosis, we carried out structural and phylogenetic analysis of two predicted D,D-carboxypeptidases, Rv2911 and Rv3330. Optimization of Rv2911 for crystallization using directed evolution and the GFP folding reporter method yielded a soluble quadruple mutant. Structures of optimized Rv2911 bound to phenylmethylsulfonyl fluoride and Rv3330 bound to meropenem show that, in contrast to the nonspecific inhibitor, meropenem forms an extended interaction with the enzyme along a conserved surface. Phylogenetic analysis shows that Rv2911 and Rv3330 belong to different clades that emerged in Actinobacteria and are not represented in model organisms such as Escherichia coli and Bacillus subtilis. Clade-specific adaptations allow these enzymes to fulfill distinct physiological roles despite strict conservation of core catalytic residues. The characteristic differences include potential protein-protein interaction surfaces and specificity-determining residues surrounding the catalytic site. Overall, these structural insights lay the groundwork to develop improved beta-lactam therapeutics for tuberculosis.
		+
		+	Subfamily-Specific Adaptations in the Structures of Two Penicillin-Binding Proteins from Mycobacterium tuberculosis.,Prigozhin DM, Krieger IV, Huizar JP, Mavrici D, Waldo GS, Hung LW, Sacchettini JC, Terwilliger TC, Alber T PLoS One. 2014 Dec 31;9(12):e116249. doi: 10.1371/journal.pone.0116249., eCollection 2014. PMID:25551456<ref>PMID:25551456</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 09:31, 25 January 2015

OCA — Sun, 25 Jan 2015 09:31:03 GMT

←Older revision		Revision as of 09:31, 25 January 2015
Line 9:		Line 9:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Alber, T.]]	+	[[Category: Alber, T]]
-	[[Category: Huizar, J P.]]	+	[[Category: Huizar, J P]]
-	[[Category: Mavrici, D.]]	+	[[Category: Mavrici, D]]
-	[[Category: Prigozhin, D M.]]	+	[[Category: Prigozhin, D M]]
-	[[Category: ~~TBSGC, TB~~ Structural ~~Genomics Consortium.~~]]	+	[[Category: Structural genomic]]
	[[Category: D-peptidase]]		[[Category: D-peptidase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
Line 20:		Line 20:
	[[Category: Penicillin-binding protein]]		[[Category: Penicillin-binding protein]]
	[[Category: Peptidoglycan d]]		[[Category: Peptidoglycan d]]
-	[[Category: Structural genomic]]
-	[[Category: Tb structural genomics consortium]]
	[[Category: Tbsgc]]		[[Category: Tbsgc]]

OCA at 08:56, 5 November 2014

OCA — Wed, 05 Nov 2014 08:56:44 GMT

←Older revision		Revision as of 08:56, 5 November 2014
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Crystal structure of Mycobacterium tuberculosis D,D-peptidase Rv3330 in complex with meropenem==
-		+	<StructureSection load='4ppr' size='340' side='right' caption='[[4ppr]], [[Resolution\|resolution]] 2.00Å' scene=''>
-	~~The entry~~ 4ppr is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4ppr]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PPR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PPR FirstGlance]. <br>
-	~~Authors~~: ~~Prigozhin~~, D.M., Huizar, J.P., Mavrici, D., ~~Alber, T~~., TB Structural Genomics Consortium ~~(TBSGC)~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MER:(4R,5S)-3-{[(3S,5S)-5-(DIMETHYLCARBAMOYL)PYRROLIDIN-3-YL]SULFANYL}-5-[(2S,3R)-3-HYDROXY-1-OXOBUTAN-2-YL]-4-METHYL-4,5-DIHYDRO-1H-PYRROLE-2-CARBOXYLIC+ACID'>MER</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4p0m\|4p0m]]</td></tr>
-	~~Description~~: ~~Crystal structure of Mycobacterium tuberculosis D,~~D-peptidase ~~Rv3330 in complex with meropenem~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ppr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ppr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ppr RCSB], [http://www.ebi.ac.uk/pdbsum/4ppr PDBsum]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Alber, T.]]
		+	[[Category: Huizar, J P.]]
		+	[[Category: Mavrici, D.]]
		+	[[Category: Prigozhin, D M.]]
		+	[[Category: TBSGC, TB Structural Genomics Consortium.]]
		+	[[Category: D-peptidase]]
		+	[[Category: Hydrolase]]
		+	[[Category: National institute of allergy and infectious disease]]
		+	[[Category: Niaid]]
		+	[[Category: Penicillin-binding protein]]
		+	[[Category: Peptidoglycan d]]
		+	[[Category: Structural genomic]]
		+	[[Category: Tb structural genomics consortium]]
		+	[[Category: Tbsgc]]

OCA at 07:27, 23 April 2014

OCA — Wed, 23 Apr 2014 07:27:05 GMT

←Older revision		Revision as of 07:27, 23 April 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4ppr is ON HOLD	+	The entry 4ppr is ON HOLD until Paper Publication

	Authors: Prigozhin, D.M., Huizar, J.P., Mavrici, D., Alber, T., TB Structural Genomics Consortium (TBSGC)		Authors: Prigozhin, D.M., Huizar, J.P., Mavrici, D., Alber, T., TB Structural Genomics Consortium (TBSGC)

	Description: Crystal structure of Mycobacterium tuberculosis D,D-peptidase Rv3330 in complex with meropenem		Description: Crystal structure of Mycobacterium tuberculosis D,D-peptidase Rv3330 in complex with meropenem

OCA: Protected "4ppr" [edit=sysop:move=sysop]

OCA — Wed, 12 Mar 2014 12:34:21 GMT

Protected "4ppr" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:34, 12 March 2014

OCA: New page: '''Unreleased structure''' The entry 4ppr is ON HOLD Authors: Prigozhin, D.M., Huizar, J.P., Mavrici, D., Alber, T., TB Structural Genomics Consortium (TBSGC) Description: Crystal stru...

OCA — Wed, 12 Mar 2014 12:34:20 GMT

New page: '''Unreleased structure''' The entry 4ppr is ON HOLD Authors: Prigozhin, D.M., Huizar, J.P., Mavrici, D., Alber, T., TB Structural Genomics Consortium (TBSGC) Description: Crystal stru...

New page

'''Unreleased structure'''

The entry 4ppr is ON HOLD

Authors: Prigozhin, D.M., Huizar, J.P., Mavrici, D., Alber, T., TB Structural Genomics Consortium (TBSGC)

Description: Crystal structure of Mycobacterium tuberculosis D,D-peptidase Rv3330 in complex with meropenem