4q3z - Revision history

OCA at 17:27, 20 September 2023

OCA — Wed, 20 Sep 2023 17:27:55 GMT

←Older revision		Revision as of 17:27, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4q3z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Chromobacterium_violaceum_ATCC_12472 Chromobacterium violaceum ATCC 12472]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q3Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q3Z FirstGlance]. <br>		<table><tr><td colspan='2'>[[4q3z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Chromobacterium_violaceum_ATCC_12472 Chromobacterium violaceum ATCC 12472]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q3Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q3Z FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.35Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q3z OCA], [https://pdbe.org/4q3z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q3z RCSB], [https://www.ebi.ac.uk/pdbsum/4q3z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q3z ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q3z OCA], [https://pdbe.org/4q3z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q3z RCSB], [https://www.ebi.ac.uk/pdbsum/4q3z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q3z ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:42, 8 February 2023

OCA — Wed, 08 Feb 2023 07:42:58 GMT

←Older revision		Revision as of 07:42, 8 February 2023
Line 3:		Line 3:
	<StructureSection load='4q3z' size='340' side='right'caption='[[4q3z]], [[Resolution\|resolution]] 1.35Å' scene=''>		<StructureSection load='4q3z' size='340' side='right'caption='[[4q3z]], [[Resolution\|resolution]] 1.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4q3z]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Chrvo Chrvo~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q3Z OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4Q3Z FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4q3z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Chromobacterium_violaceum_ATCC_12472 Chromobacterium violaceum ATCC 12472]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q3Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q3Z FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3tk4\|3tk4]], [[1ltv\|1ltv]], [[4q3w\|4q3w]], [[4q3x\|4q3x]], [[4q3y\|4q3y]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q3z OCA], [https://pdbe.org/4q3z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q3z RCSB], [https://www.ebi.ac.uk/pdbsum/4q3z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q3z ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">phhA, CV_3180 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243365 CHRVO])</td></tr>	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4q3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q3z OCA], [~~http~~://pdbe.org/4q3z PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4q3z RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4q3z PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4q3z ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PH4H_CHRVO PH4H_CHRVO]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Chrvo~~]]	+	[[Category: Chromobacterium violaceum ATCC 12472]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Phenylalanine 4-monooxygenase]]~~	+	[[Category: Abu-Omar MM]]
-	[[Category: Abu-Omar~~, M M~~]]	+	[[Category: Das C]]
-	[[Category: Das, C]]	+	[[Category: Ronau JA]]
-	[[Category: Ronau~~, J A]]~~	+
-	~~[[Category: Biopterin]]~~	+
-	~~[[Category: Chromobacterium]]~~	+
-	~~[[Category: Hydroxylase]]~~	+
-	~~[[Category: Kinetic]]~~	+
-	~~[[Category: Metal]]~~	+
-	~~[[Category: Mixed alpha helix-beta sheet]]~~	+
-	~~[[Category: Mutation]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Phenylalanine hydroxylase]]~~	+
-	~~[[Category: Phenylketonuria~~]]	+

OCA at 16:00, 20 November 2019

OCA — Wed, 20 Nov 2019 16:00:28 GMT

←Older revision		Revision as of 16:00, 20 November 2019
Line 21:		Line 21:

	==See Also==		==See Also==
-	*[[~~Hydroxylase~~\|~~Hydroxylase~~]]	+	*[[Hydroxylases 3D structures\|Hydroxylases 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:21, 24 April 2019

OCA — Wed, 24 Apr 2019 09:21:48 GMT

←Older revision		Revision as of 09:21, 24 April 2019
Line 1:		Line 1:

	==Crystal structure of C. violaceum phenylalanine hydroxylase D139K mutation==		==Crystal structure of C. violaceum phenylalanine hydroxylase D139K mutation==
-	<StructureSection load='4q3z' size='340' side='right' caption='[[4q3z]], [[Resolution\|resolution]] 1.35Å' scene=''>	+	<StructureSection load='4q3z' size='340' side='right'caption='[[4q3z]], [[Resolution\|resolution]] 1.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4q3z]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q3Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q3Z FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4q3z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chrvo Chrvo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q3Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q3Z FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3tk4\|3tk4]], [[1ltv\|1ltv]], [[4q3w\|4q3w]], [[4q3x\|4q3x]], [[4q3y\|4q3y]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3tk4\|3tk4]], [[1ltv\|1ltv]], [[4q3w\|4q3w]], [[4q3x\|4q3x]], [[4q3y\|4q3y]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">phhA, CV_3180 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243365 CHRVO])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q3z OCA], [http://pdbe.org/4q3z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q3z RCSB], [http://www.ebi.ac.uk/pdbsum/4q3z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4q3z ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q3z OCA], [http://pdbe.org/4q3z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q3z RCSB], [http://www.ebi.ac.uk/pdbsum/4q3z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4q3z ProSAT]</span></td></tr>
Line 25:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Chrvo]]
		+	[[Category: Large Structures]]
	[[Category: Phenylalanine 4-monooxygenase]]		[[Category: Phenylalanine 4-monooxygenase]]
	[[Category: Abu-Omar, M M]]		[[Category: Abu-Omar, M M]]

OCA at 17:05, 4 January 2017

OCA — Wed, 04 Jan 2017 17:05:37 GMT

←Older revision		Revision as of 17:05, 4 January 2017
Line 1:		Line 1:
		+
	==Crystal structure of C. violaceum phenylalanine hydroxylase D139K mutation==		==Crystal structure of C. violaceum phenylalanine hydroxylase D139K mutation==
	<StructureSection load='4q3z' size='340' side='right' caption='[[4q3z]], [[Resolution\|resolution]] 1.35Å' scene=''>		<StructureSection load='4q3z' size='340' side='right' caption='[[4q3z]], [[Resolution\|resolution]] 1.35Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3tk4\|3tk4]], [[1ltv\|1ltv]], [[4q3w\|4q3w]], [[4q3x\|4q3x]], [[4q3y\|4q3y]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3tk4\|3tk4]], [[1ltv\|1ltv]], [[4q3w\|4q3w]], [[4q3x\|4q3x]], [[4q3y\|4q3y]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q3z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q3z RCSB], [http://www.ebi.ac.uk/pdbsum/4q3z PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q3z OCA], [http://pdbe.org/4q3z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q3z RCSB], [http://www.ebi.ac.uk/pdbsum/4q3z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4q3z ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4q3z" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Hydroxylase\|Hydroxylase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:00, 18 February 2015

OCA — Wed, 18 Feb 2015 13:00:38 GMT

←Older revision		Revision as of 13:00, 18 February 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal structure of C. violaceum phenylalanine hydroxylase D139K mutation==
		+	<StructureSection load='4q3z' size='340' side='right' caption='[[4q3z]], [[Resolution\|resolution]] 1.35Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4q3z]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q3Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q3Z FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3tk4\|3tk4]], [[1ltv\|1ltv]], [[4q3w\|4q3w]], [[4q3x\|4q3x]], [[4q3y\|4q3y]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q3z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q3z RCSB], [http://www.ebi.ac.uk/pdbsum/4q3z PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The catalytic domains of aromatic amino acid hydroxylases (AAAHs) contain a non-heme iron coordinated to a 2-His-1-carboxylate facial triad and two water molecules. Asp139 from Chromobacterium violaceum PAH (cPAH) resides within the second coordination sphere and contributes key hydrogen bonds with three active site waters that mediate its interaction with an oxidized form of the cofactor, 7,8-dihydro-l-biopterin, in crystal structures. To determine the catalytic role of this residue, various point mutants were prepared and characterized. Our isothermal titration calorimetry (ITC) analysis of iron binding implies that polarity at position 139 is not the sole criterion for metal affinity, as binding studies with D139E suggest that the size of the amino acid side chain also appears to be important. High-resolution crystal structures of the mutants reveal that Asp139 may not be essential for holding the bridging water molecules together, because many of these waters are retained even in the Ala mutant. However, interactions via the bridging waters contribute to cofactor binding at the active site, interactions for which charge of the residue is important, as the D139N mutant shows a 5-fold decrease in its affinity for pterin as revealed by ITC (compared to a 16-fold loss of affinity in the case of the Ala mutant). The Asn and Ala mutants show a much more pronounced defect in their kcat values, with nearly 16- and 100-fold changes relative to that of the wild type, respectively, indicating a substantial role of this residue in stabilization of the transition state by aligning the cofactor in a productive orientation, most likely through direct binding with the cofactor, supported by data from molecular dynamics simulations of the complexes. Our results indicate that the intervening water structure between the cofactor and the acidic residue masks direct interaction between the two, possibly to prevent uncoupled hydroxylation of the cofactor before the arrival of phenylalanine. It thus appears that the second-coordination sphere Asp residue in cPAH, and, by extrapolation, the equivalent residue in other AAAHs, plays a role in fine-tuning pterin affinity in the ground state via deformable interactions with bridging waters and assumes a more significant role in the transition state by aligning the cofactor through direct hydrogen bonding.

-	~~The entry 4q3z is ON HOLD until Paper Publication~~	+	A conserved acidic residue in phenylalanine hydroxylase contributes to cofactor affinity and catalysis.,Ronau JA, Paul LN, Fuchs JE, Liedl KR, Abu-Omar MM, Das C Biochemistry. 2014 Nov 4;53(43):6834-48. doi: 10.1021/bi500734h. Epub 2014 Oct, 23. PMID:25295853<ref>PMID:25295853</ref>

-	~~Authors: Ronau~~, J.A.~~, Abu-Omar, M.M., Das, C~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description: Crystal structure of C. violaceum phenylalanine hydroxylase D139K mutation~~	+	== References ==
-	[[Category: ~~Unreleased Structures~~]]	+	<references/>
-	[[Category: ~~Ronau~~, ~~J.A~~]]	+	__TOC__
		+	</StructureSection>
		+	[[Category: Phenylalanine 4-monooxygenase]]
		+	[[Category: Abu-Omar, M M]]
	[[Category: Das, C]]		[[Category: Das, C]]
-	[[Category: ~~Abu-Omar~~, ~~M.M~~]]	+	[[Category: Ronau, J A]]
		+	[[Category: Biopterin]]
		+	[[Category: Chromobacterium]]
		+	[[Category: Hydroxylase]]
		+	[[Category: Kinetic]]
		+	[[Category: Metal]]
		+	[[Category: Mixed alpha helix-beta sheet]]
		+	[[Category: Mutation]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Phenylalanine hydroxylase]]
		+	[[Category: Phenylketonuria]]

OCA at 15:24, 24 December 2014

OCA — Wed, 24 Dec 2014 15:24:38 GMT

←Older revision		Revision as of 15:24, 24 December 2014
Line 6:		Line 6:

	Description: Crystal structure of C. violaceum phenylalanine hydroxylase D139K mutation		Description: Crystal structure of C. violaceum phenylalanine hydroxylase D139K mutation
		+	[[Category: Unreleased Structures]]
		+	[[Category: Ronau, J.A]]
		+	[[Category: Das, C]]
		+	[[Category: Abu-Omar, M.M]]

OCA at 08:05, 24 September 2014

OCA — Wed, 24 Sep 2014 08:05:54 GMT

←Older revision		Revision as of 08:05, 24 September 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4q3z is ON HOLD	+	The entry 4q3z is ON HOLD until Paper Publication

	Authors: Ronau, J.A., Abu-Omar, M.M., Das, C.		Authors: Ronau, J.A., Abu-Omar, M.M., Das, C.

	Description: Crystal structure of C. violaceum phenylalanine hydroxylase D139K mutation		Description: Crystal structure of C. violaceum phenylalanine hydroxylase D139K mutation

OCA: Protected "4q3z" [edit=sysop:move=sysop]

OCA — Wed, 23 Apr 2014 07:29:17 GMT

Protected "4q3z" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:29, 23 April 2014

OCA: New page: '''Unreleased structure''' The entry 4q3z is ON HOLD Authors: Ronau, J.A., Abu-Omar, M.M., Das, C. Description: Crystal structure of C. violaceum phenylalanine hydroxylase D139K mutati...

OCA — Wed, 23 Apr 2014 07:29:16 GMT

New page: '''Unreleased structure''' The entry 4q3z is ON HOLD Authors: Ronau, J.A., Abu-Omar, M.M., Das, C. Description: Crystal structure of C. violaceum phenylalanine hydroxylase D139K mutati...

New page

'''Unreleased structure'''

The entry 4q3z is ON HOLD

Authors: Ronau, J.A., Abu-Omar, M.M., Das, C.

Description: Crystal structure of C. violaceum phenylalanine hydroxylase D139K mutation