4q8r - Revision history

OCA at 17:29, 20 September 2023

OCA — Wed, 20 Sep 2023 17:29:40 GMT

←Older revision		Revision as of 17:29, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4q8r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q8R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q8R FirstGlance]. <br>		<table><tr><td colspan='2'>[[4q8r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q8R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q8R FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.65Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q8r OCA], [https://pdbe.org/4q8r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q8r RCSB], [https://www.ebi.ac.uk/pdbsum/4q8r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q8r ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q8r OCA], [https://pdbe.org/4q8r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q8r RCSB], [https://www.ebi.ac.uk/pdbsum/4q8r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q8r ProSAT]</span></td></tr>
	</table>		</table>

OCA at 11:18, 15 February 2023

OCA — Wed, 15 Feb 2023 11:18:08 GMT

←Older revision		Revision as of 11:18, 15 February 2023
Line 3:		Line 3:
	<StructureSection load='4q8r' size='340' side='right'caption='[[4q8r]], [[Resolution\|resolution]] 1.65Å' scene=''>		<StructureSection load='4q8r' size='340' side='right'caption='[[4q8r]], [[Resolution\|resolution]] 1.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4q8r]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_perfringens"_veillon_and_zuber_1898 "bacillus~~ perfringens~~" veillon and zuber 1898~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q8R OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4Q8R FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4q8r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q8R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q8R FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4gd5\|4gd5]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q8r OCA], [https://pdbe.org/4q8r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q8r RCSB], [https://www.ebi.ac.uk/pdbsum/4q8r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q8r ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pstS, CPF_0617 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1502 "Bacillus perfringens" Veillon and Zuber 1898])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4q8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q8r OCA], [~~http~~://pdbe.org/4q8r PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4q8r RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4q8r PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4q8r ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A0H2YSI2_CLOP1 A0A0H2YSI2_CLOP1]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4q8r" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4q8r" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[ABC transporter 3D structures\|ABC transporter 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ perfringens ~~veillon and zuber 1898~~]]	+	[[Category: Clostridium perfringens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bergonzi, C]]	+	[[Category: Bergonzi C]]
-	[[Category: Chabriere, E]]	+	[[Category: Chabriere E]]
-	[[Category: Elias, M]]	+	[[Category: Elias M]]
-	[[Category: Gonzalez, D]]	+	[[Category: Gonzalez D]]
-	[[Category: Richez, M]]	+	[[Category: Richez M]]
-	~~[[Category: Periplasmic high affinity phosphate binding protein]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 09:13, 24 April 2019

OCA — Wed, 24 Apr 2019 09:13:47 GMT

←Older revision		Revision as of 09:13, 24 April 2019
Line 1:		Line 1:

	==Crystal structure of a Phosphate Binding Protein (PBP-1) from Clostridium perfringens==		==Crystal structure of a Phosphate Binding Protein (PBP-1) from Clostridium perfringens==
-	<StructureSection load='4q8r' size='340' side='right' caption='[[4q8r]], [[Resolution\|resolution]] 1.65Å' scene=''>	+	<StructureSection load='4q8r' size='340' side='right'caption='[[4q8r]], [[Resolution\|resolution]] 1.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4q8r]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q8R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q8R FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4q8r]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_perfringens"_veillon_and_zuber_1898 "bacillus perfringens" veillon and zuber 1898]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q8R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q8R FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4gd5\|4gd5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4gd5\|4gd5]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pstS, CPF_0617 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1502 "Bacillus perfringens" Veillon and Zuber 1898])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q8r OCA], [http://pdbe.org/4q8r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q8r RCSB], [http://www.ebi.ac.uk/pdbsum/4q8r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4q8r ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q8r OCA], [http://pdbe.org/4q8r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q8r RCSB], [http://www.ebi.ac.uk/pdbsum/4q8r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4q8r ProSAT]</span></td></tr>
	</table>		</table>
Line 21:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacillus perfringens veillon and zuber 1898]]
		+	[[Category: Large Structures]]
	[[Category: Bergonzi, C]]		[[Category: Bergonzi, C]]
	[[Category: Chabriere, E]]		[[Category: Chabriere, E]]

OCA at 15:30, 11 August 2016

OCA — Thu, 11 Aug 2016 15:30:21 GMT

←Older revision		Revision as of 15:30, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of a Phosphate Binding Protein (PBP-1) from Clostridium perfringens==		==Crystal structure of a Phosphate Binding Protein (PBP-1) from Clostridium perfringens==
	<StructureSection load='4q8r' size='340' side='right' caption='[[4q8r]], [[Resolution\|resolution]] 1.65Å' scene=''>		<StructureSection load='4q8r' size='340' side='right' caption='[[4q8r]], [[Resolution\|resolution]] 1.65Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4gd5\|4gd5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4gd5\|4gd5]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q8r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q8r RCSB], [http://www.ebi.ac.uk/pdbsum/4q8r PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q8r OCA], [http://pdbe.org/4q8r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q8r RCSB], [http://www.ebi.ac.uk/pdbsum/4q8r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4q8r ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4q8r" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:52, 25 January 2015

OCA — Sun, 25 Jan 2015 09:52:05 GMT

←Older revision		Revision as of 09:52, 25 January 2015
Line 19:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bergonzi, C.]]	+	[[Category: Bergonzi, C]]
-	[[Category: Chabriere, E.]]	+	[[Category: Chabriere, E]]
-	[[Category: Elias, M.]]	+	[[Category: Elias, M]]
-	[[Category: Gonzalez, D.]]	+	[[Category: Gonzalez, D]]
-	[[Category: Richez, M.]]	+	[[Category: Richez, M]]
	[[Category: Periplasmic high affinity phosphate binding protein]]		[[Category: Periplasmic high affinity phosphate binding protein]]
	[[Category: Transport protein]]		[[Category: Transport protein]]

OCA at 08:44, 5 November 2014

OCA — Wed, 05 Nov 2014 08:44:46 GMT

←Older revision		Revision as of 08:44, 5 November 2014
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal structure of a Phosphate Binding Protein (PBP-1) from Clostridium perfringens==
		+	<StructureSection load='4q8r' size='340' side='right' caption='[[4q8r]], [[Resolution\|resolution]] 1.65Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4q8r]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q8R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q8R FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4gd5\|4gd5]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q8r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q8r RCSB], [http://www.ebi.ac.uk/pdbsum/4q8r PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Phosphate limitation is an important environmental stress that affects the metabolism of various organisms and, in particular, can trigger the virulence of numerous bacterial pathogens. Clostridium perfringens, a human pathogen, is one of the most common causes of enteritis necroticans, gas gangrene and food poisoning. Here, we focused on the high affinity phosphate-binding protein (PBP-1) of an ABC-type transporter, responsible for cellular phosphate uptake. We report the crystal structure (1.65 A resolution) of the protein in complex with phosphate. Interestingly, PBP-1 does not form the short, low-barrier hydrogen bond with phosphate that is typical of previously characterized phosphate-binding proteins, but rather a canonical hydrogen bond. In its unique binding configuration, PBP-1 forms an unusually high number of hydrogen bonds (14) with the phosphate anion. Discrimination experiments reveal that PBP-1 is the least selective PBP characterised so far and is able to discriminate phosphate from its close competing anion, arsenate, by ~150-fold.

-	~~The entry 4q8r is ON HOLD until Paper Publication~~	+	Crystal structure of the phosphate-binding protein (PBP-1) of an ABC-type phosphate transporter from Clostridium perfringens.,Gonzalez D, Richez M, Bergonzi C, Chabriere E, Elias M Sci Rep. 2014 Oct 16;4:6636. doi: 10.1038/srep06636. PMID:25338617<ref>PMID:25338617</ref>

-	~~Authors: Gonzalez~~, D.~~, Richez, M~~., Bergonzi, C., Chabriere, E., Elias, M.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Crystal structure of a Phosphate Binding Protein (PBP-1) from Clostridium perfringens~~	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Bergonzi, C.]]
		+	[[Category: Chabriere, E.]]
		+	[[Category: Elias, M.]]
		+	[[Category: Gonzalez, D.]]
		+	[[Category: Richez, M.]]
		+	[[Category: Periplasmic high affinity phosphate binding protein]]
		+	[[Category: Transport protein]]

OCA at 08:06, 24 September 2014

OCA — Wed, 24 Sep 2014 08:06:54 GMT

←Older revision		Revision as of 08:06, 24 September 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4q8r is ON HOLD	+	The entry 4q8r is ON HOLD until Paper Publication

	Authors: Gonzalez, D., Richez, M., Bergonzi, C., Chabriere, E., Elias, M.		Authors: Gonzalez, D., Richez, M., Bergonzi, C., Chabriere, E., Elias, M.

	Description: Crystal structure of a Phosphate Binding Protein (PBP-1) from Clostridium perfringens		Description: Crystal structure of a Phosphate Binding Protein (PBP-1) from Clostridium perfringens

OCA: Protected "4q8r" [edit=sysop:move=sysop]

OCA — Wed, 07 May 2014 07:51:10 GMT

Protected "4q8r" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:51, 7 May 2014

OCA: New page: '''Unreleased structure''' The entry 4q8r is ON HOLD Authors: Gonzalez, D., Richez, M., Bergonzi, C., Chabriere, E., Elias, M. Description: Crystal structure of a Phosphate Binding Pro...

OCA — Wed, 07 May 2014 07:51:09 GMT

New page: '''Unreleased structure''' The entry 4q8r is ON HOLD Authors: Gonzalez, D., Richez, M., Bergonzi, C., Chabriere, E., Elias, M. Description: Crystal structure of a Phosphate Binding Pro...

New page

'''Unreleased structure'''

The entry 4q8r is ON HOLD

Authors: Gonzalez, D., Richez, M., Bergonzi, C., Chabriere, E., Elias, M.

Description: Crystal structure of a Phosphate Binding Protein (PBP-1) from Clostridium perfringens