4q92 - Revision history

OCA at 17:29, 20 September 2023

OCA — Wed, 20 Sep 2023 17:29:53 GMT

←Older revision		Revision as of 17:29, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4q92]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_COL Staphylococcus aureus subsp. aureus COL]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q92 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q92 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4q92]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_COL Staphylococcus aureus subsp. aureus COL]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q92 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q92 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q92 OCA], [https://pdbe.org/4q92 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q92 RCSB], [https://www.ebi.ac.uk/pdbsum/4q92 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q92 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q92 OCA], [https://pdbe.org/4q92 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q92 RCSB], [https://www.ebi.ac.uk/pdbsum/4q92 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q92 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 11:18, 15 February 2023

OCA — Wed, 15 Feb 2023 11:18:39 GMT

←Older revision		Revision as of 11:18, 15 February 2023
Line 1:		Line 1:

	==1.90 Angstrom resolution crystal structure of apo betaine aldehyde dehydrogenase (betB) G234S mutant from Staphylococcus aureus (IDP00699) with BME-modified Cys289==		==1.90 Angstrom resolution crystal structure of apo betaine aldehyde dehydrogenase (betB) G234S mutant from Staphylococcus aureus (IDP00699) with BME-modified Cys289==
-	<StructureSection load='4q92' size='340' side='right' caption='[[4q92]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='4q92' size='340' side='right'caption='[[4q92]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4q92]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Staac Staac~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q92 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4Q92 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4q92]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_COL Staphylococcus aureus subsp. aureus COL]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q92 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q92 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-	~~<tr~~ id~~='NonStdRes'><td class~~="~~sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat~~"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene><~~/td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q92 OCA], [https://pdbe.org/4q92 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q92 RCSB], [https://www.ebi.ac.uk/pdbsum/4q92 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q92 ProSAT]</span></td></tr>
-	~~<tr id~~='~~related'><td class~~=~~"sblockLbl"><b>[[Related_structure\|Related~~:~~]]</b~~></td>~~<td class="sblockDat">[[4mpb\|4mpb]]~~, ~~[[4mpy\|4mpy]], [[4nea\|4nea]], [[4ni4\|4ni4]], [[4nu9\|4nu9]]~~<~~/td></tr>~~	+
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b></td><td class="sblockDat">betB, SACOL2628~~ (~~[http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93062 STAAC]~~)~~</td></tr>~~	+
-	~~<tr id='activity~~'>~~<td class="sblockLbl"><b>Activity:~~</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Betaine-aldehyde_dehydrogenase Betaine-aldehyde dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.8 1.2.1.8] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4q92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q92 OCA], [~~http~~://pdbe.org/4q92 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4q92 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4q92 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4q92 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A0H2X0S3_STAAC A0A0H2X0S3_STAAC]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 4q92" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4q92" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Aldehyde dehydrogenase 3D structures\|Aldehyde dehydrogenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Betaine-aldehyde dehydrogenase~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Staac~~]]	+	[[Category: Staphylococcus aureus subsp. aureus COL]]
-	[[Category: Anderson~~, W F]]~~	+	[[Category: Anderson WF]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Chen C]]
-	[[Category: Chen, C]]	+	[[Category: Halavaty AS]]
-	[[Category: Halavaty~~, A S~~]]	+	[[Category: Joo JC]]
-	[[Category: Joo~~, J C~~]]	+	[[Category: Minasov G]]
-	[[Category: Minasov, G]]	+	[[Category: Yakunin AF]]
-	[[Category: Yakunin~~, A F]]~~	+
-	~~[[Category: Csgid]]~~	+
-	~~[[Category: Nad]]~~	+
-	~~[[Category: National institute of allergy and infectious disease]]~~	+
-	~~[[Category: Niaid]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Rossmann fold~~]]	+

OCA at 08:50, 22 November 2017

OCA — Wed, 22 Nov 2017 08:50:53 GMT

←Older revision		Revision as of 08:50, 22 November 2017
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	<StructureSection load='4q92' size='340' side='right' caption='[[4q92]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='4q92' size='340' side='right' caption='[[4q92]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4q92]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q92 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q92 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4q92]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staac Staac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q92 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q92 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4mpb\|4mpb]], [[4mpy\|4mpy]], [[4nea\|4nea]], [[4ni4\|4ni4]], [[4nu9\|4nu9]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4mpb\|4mpb]], [[4mpy\|4mpy]], [[4nea\|4nea]], [[4ni4\|4ni4]], [[4nu9\|4nu9]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">betB, SACOL2628 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93062 STAAC])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Betaine-aldehyde_dehydrogenase Betaine-aldehyde dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.8 1.2.1.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Betaine-aldehyde_dehydrogenase Betaine-aldehyde dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.8 1.2.1.8] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q92 OCA], [http://pdbe.org/4q92 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q92 RCSB], [http://www.ebi.ac.uk/pdbsum/4q92 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4q92 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q92 OCA], [http://pdbe.org/4q92 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q92 RCSB], [http://www.ebi.ac.uk/pdbsum/4q92 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4q92 ProSAT]</span></td></tr>
Line 19:		Line 20:
	</div>		</div>
	<div class="pdbe-citations 4q92" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4q92" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Aldehyde dehydrogenase\|Aldehyde dehydrogenase]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Betaine-aldehyde dehydrogenase]]		[[Category: Betaine-aldehyde dehydrogenase]]
		+	[[Category: Staac]]
	[[Category: Anderson, W F]]		[[Category: Anderson, W F]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]

OCA at 17:32, 9 March 2017

OCA — Thu, 09 Mar 2017 17:32:41 GMT

←Older revision		Revision as of 17:32, 9 March 2017
Line 1:		Line 1:
		+
	==1.90 Angstrom resolution crystal structure of apo betaine aldehyde dehydrogenase (betB) G234S mutant from Staphylococcus aureus (IDP00699) with BME-modified Cys289==		==1.90 Angstrom resolution crystal structure of apo betaine aldehyde dehydrogenase (betB) G234S mutant from Staphylococcus aureus (IDP00699) with BME-modified Cys289==
	<StructureSection load='4q92' size='340' side='right' caption='[[4q92]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='4q92' size='340' side='right' caption='[[4q92]], [[Resolution\|resolution]] 1.90Å' scene=''>
Line 7:		Line 8:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4mpb\|4mpb]], [[4mpy\|4mpy]], [[4nea\|4nea]], [[4ni4\|4ni4]], [[4nu9\|4nu9]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4mpb\|4mpb]], [[4mpy\|4mpy]], [[4nea\|4nea]], [[4ni4\|4ni4]], [[4nu9\|4nu9]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Betaine-aldehyde_dehydrogenase Betaine-aldehyde dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.8 1.2.1.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Betaine-aldehyde_dehydrogenase Betaine-aldehyde dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.8 1.2.1.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q92 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q92 RCSB], [http://www.ebi.ac.uk/pdbsum/4q92 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q92 OCA], [http://pdbe.org/4q92 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q92 RCSB], [http://www.ebi.ac.uk/pdbsum/4q92 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4q92 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4q92" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 06:46, 3 June 2015

OCA — Wed, 03 Jun 2015 06:46:20 GMT

←Older revision		Revision as of 06:46, 3 June 2015
Line 9:		Line 9:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q92 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q92 RCSB], [http://www.ebi.ac.uk/pdbsum/4q92 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q92 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q92 RCSB], [http://www.ebi.ac.uk/pdbsum/4q92 PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	When exposed to high osmolarity, methicillin-resistant Staphylococcus aureus (MRSA) restores its growth and establishes a new steady state by accumulating the osmoprotectant metabolite betaine. Effective osmoregulation has also been implicated in the acquirement of a profound antibiotic resistance by MRSA. Betaine can be obtained from the bacterial habitat or produced intracellularly from choline via the toxic betaine aldehyde (BA) employing the choline dehydrogenase and betaine aldehyde dehydrogenase (BADH) enzymes. Here, it is shown that the putative betaine aldehyde dehydrogenase SACOL2628 from the early MRSA isolate COL (SaBADH) utilizes betaine aldehyde as the primary substrate and nicotinamide adenine dinucleotide (NAD(+)) as the cofactor. Surface plasmon resonance experiments revealed that the affinity of NAD(+), NADH and BA for SaBADH is affected by temperature, pH and buffer composition. Five crystal structures of the wild type and three structures of the Gly234Ser mutant of SaBADH in the apo and holo forms provide details of the molecular mechanisms of activity and substrate specificity/inhibition of this enzyme.
		+
		+	Structural and functional analysis of betaine aldehyde dehydrogenase from Staphylococcus aureus.,Halavaty AS, Rich RL, Chen C, Joo JC, Minasov G, Dubrovska I, Winsor JR, Myszka DG, Duban M, Shuvalova L, Yakunin AF, Anderson WF Acta Crystallogr D Biol Crystallogr. 2015 May;71(Pt 5):1159-75. doi:, 10.1107/S1399004715004228. Epub 2015 Apr 25. PMID:25945581<ref>PMID:25945581</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Aldehyde dehydrogenase\|Aldehyde dehydrogenase]]		*[[Aldehyde dehydrogenase\|Aldehyde dehydrogenase]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 06:20, 13 May 2015

OCA — Wed, 13 May 2015 06:20:32 GMT

←Older revision		Revision as of 06:20, 13 May 2015
Line 9:		Line 9:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q92 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q92 RCSB], [http://www.ebi.ac.uk/pdbsum/4q92 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q92 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q92 RCSB], [http://www.ebi.ac.uk/pdbsum/4q92 PDBsum]</span></td></tr>
	</table>		</table>
		+
		+	==See Also==
		+	*[[Aldehyde dehydrogenase\|Aldehyde dehydrogenase]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 09:46, 5 January 2015

OCA — Mon, 05 Jan 2015 09:46:04 GMT

←Older revision		Revision as of 09:46, 5 January 2015
Line 2:		Line 2:
	<StructureSection load='4q92' size='340' side='right' caption='[[4q92]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='4q92' size='340' side='right' caption='[[4q92]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4q92]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q92 OCA]. <br>	+	<table><tr><td colspan='2'>[[4q92]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q92 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q92 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4mpb\|4mpb]], [[4mpy\|4mpy]], [[4nea\|4nea]], [[4ni4\|4ni4]], [[4nu9\|4nu9]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4mpb\|4mpb]], [[4mpy\|4mpy]], [[4nea\|4nea]], [[4ni4\|4ni4]], [[4nu9\|4nu9]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/~~Glucokinase Glucokinase~~], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Betaine-aldehyde_dehydrogenase Betaine-aldehyde dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.8 1.2.1.8] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q92 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q92 RCSB], [http://www.ebi.ac.uk/pdbsum/4q92 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q92 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q92 RCSB], [http://www.ebi.ac.uk/pdbsum/4q92 PDBsum]</span></td></tr>
-	<table>	+	</table>
-	~~== References ==~~	+
-	~~<references/~~>	+
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Betaine-aldehyde dehydrogenase]]		[[Category: Betaine-aldehyde dehydrogenase]]
-	[[Category: Anderson, W F.]]	+	[[Category: Anderson, W F]]
-	[[Category: ~~CSGID, Center for~~ Structural ~~Genomics of Infectious Diseases.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Chen, C.]]	+	[[Category: Chen, C]]
-	[[Category: Halavaty, A S.]]	+	[[Category: Halavaty, A S]]
-	[[Category: Joo, J C.]]	+	[[Category: Joo, J C]]
-	[[Category: Minasov, G.]]	+	[[Category: Minasov, G]]
-	[[Category: Yakunin, A F~~.]]~~	+	[[Category: Yakunin, A F]]
-	~~[[Category: Center for structural genomics of infectious~~]]	+
	[[Category: Csgid]]		[[Category: Csgid]]
	[[Category: Nad]]		[[Category: Nad]]
Line 28:		Line 25:
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: Rossmann fold]]		[[Category: Rossmann fold]]
-	[[Category: Structural genomic]]

OCA: Protected "4q92" [edit=sysop:move=sysop]

OCA — Wed, 07 May 2014 08:25:24 GMT

Protected "4q92" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:25, 7 May 2014

OCA: New page: ==1.90 Angstrom resolution crystal structure of apo betaine aldehyde dehydrogenase (betB) G234S mutant from Staphylococcus aureus (IDP00699) with BME-modified Cys289==
OCA — Wed, 07 May 2014 08:25:22 GMT

New page: ==1.90 Angstrom resolution crystal structure of apo betaine aldehyde dehydrogenase (betB) G234S mutant from Staphylococcus aureus (IDP00699) with BME-modified Cys289== <StructureSection lo...

New page
==1.90 Angstrom resolution crystal structure of apo betaine aldehyde dehydrogenase (betB) G234S mutant from Staphylococcus aureus (IDP00699) with BME-modified Cys289==
<StructureSection load='4q92' size='340' side='right' caption='[[4q92]], [[Resolution|resolution]] 1.90Å' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4q92]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q92 OCA]. 
</td></tr><tr><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene> 
<tr><td class="sblockLbl">[[Non-Standard_Residue|NonStd Res:]]</td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
<tr><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4mpb|4mpb]], [[4mpy|4mpy]], [[4nea|4nea]], [[4ni4|4ni4]], [[4nu9|4nu9]]</td></tr>
<tr><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </td></tr>
<tr><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q92 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q92 RCSB], [http://www.ebi.ac.uk/pdbsum/4q92 PDBsum]</td></tr>
<table>
== References ==
<references/>
TOC
</StructureSection>
[[Category: Betaine-aldehyde dehydrogenase]]
[[Category: Anderson, W F.]]
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
[[Category: Chen, C.]]
[[Category: Halavaty, A S.]]
[[Category: Joo, J C.]]
[[Category: Minasov, G.]]
[[Category: Yakunin, A F.]]
[[Category: Center for structural genomics of infectious]]
[[Category: Csgid]]
[[Category: Nad]]
[[Category: National institute of allergy and infectious disease]]
[[Category: Niaid]]
[[Category: Oxidoreductase]]
[[Category: Rossmann fold]]
[[Category: Structural genomic]]