4qf9 - Revision history

OCA at 17:31, 20 September 2023

OCA — Wed, 20 Sep 2023 17:31:25 GMT

←Older revision		Revision as of 17:31, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4qf9]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QF9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QF9 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4qf9]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QF9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QF9 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=35K:(2S)-2-AMINO-4-(2,3-DIOXO-1,2,3,4-TETRAHYDROQUINOXALIN-6-YL)BUTANOIC+ACID'>35K</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.28Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=35K:(2S)-2-AMINO-4-(2,3-DIOXO-1,2,3,4-TETRAHYDROQUINOXALIN-6-YL)BUTANOIC+ACID'>35K</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qf9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qf9 OCA], [https://pdbe.org/4qf9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qf9 RCSB], [https://www.ebi.ac.uk/pdbsum/4qf9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qf9 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qf9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qf9 OCA], [https://pdbe.org/4qf9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qf9 RCSB], [https://www.ebi.ac.uk/pdbsum/4qf9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qf9 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 11:27, 15 February 2023

OCA — Wed, 15 Feb 2023 11:27:37 GMT

←Older revision		Revision as of 11:27, 15 February 2023
Line 3:		Line 3:
	<StructureSection load='4qf9' size='340' side='right'caption='[[4qf9]], [[Resolution\|resolution]] 2.28Å' scene=''>		<StructureSection load='4qf9' size='340' side='right'caption='[[4qf9]], [[Resolution\|resolution]] 2.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4qf9]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QF9 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4QF9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4qf9]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QF9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QF9 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=35K:(2S)-2-AMINO-4-(2,3-DIOXO-1,2,3,4-TETRAHYDROQUINOXALIN-6-YL)BUTANOIC+ACID'>35K</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=35K:(2S)-2-AMINO-4-(2,3-DIOXO-1,2,3,4-TETRAHYDROQUINOXALIN-6-YL)BUTANOIC+ACID'>35K</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4qf9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qf9 OCA], [~~http~~://pdbe.org/4qf9 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4qf9 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4qf9 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4qf9 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qf9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qf9 OCA], [https://pdbe.org/4qf9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qf9 RCSB], [https://www.ebi.ac.uk/pdbsum/4qf9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qf9 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/GRIK1_RAT GRIK1_RAT]] Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.<ref>PMID:16540562</ref>	+	[https://www.uniprot.org/uniprot/GRIK1_RAT GRIK1_RAT] Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.<ref>PMID:16540562</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Frydenvang, K~~]]	+	[[Category: Rattus norvegicus]]
-	[[Category: ~~Kastrup, J S~~]]	+	[[Category: Frydenvang K]]
-	[[Category: ~~Kristensen, C M~~]]	+	[[Category: Kastrup JS]]
-	[[Category: ~~Antagonist]]~~	+	[[Category: Kristensen CM]]
-	~~[[Category: Gluk1-s1s2]]~~	+
-	~~[[Category: Kainate receptor ligand-binding domain]]~~	+
-	~~[[Category: Membrane protein~~]]	+

OCA at 08:05, 19 February 2020

OCA — Wed, 19 Feb 2020 08:05:50 GMT

←Older revision		Revision as of 08:05, 19 February 2020
Line 1:		Line 1:

	==Structure of GluK1 ligand-binding domain (S1S2) in complex with (S)-2-amino-4-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)butanoic acid at 2.28 A resolution==		==Structure of GluK1 ligand-binding domain (S1S2) in complex with (S)-2-amino-4-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)butanoic acid at 2.28 A resolution==
-	<StructureSection load='4qf9' size='340' side='right' caption='[[4qf9]], [[Resolution\|resolution]] 2.28Å' scene=''>	+	<StructureSection load='4qf9' size='340' side='right'caption='[[4qf9]], [[Resolution\|resolution]] 2.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4qf9]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QF9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QF9 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4qf9]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QF9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QF9 FirstGlance]. <br>
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4qf9" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4qf9" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Glutamate receptor 3D structures\|Glutamate receptor 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Frydenvang, K]]		[[Category: Frydenvang, K]]
	[[Category: Kastrup, J S]]		[[Category: Kastrup, J S]]

OCA at 05:48, 16 November 2017

OCA — Thu, 16 Nov 2017 05:48:48 GMT

←Older revision		Revision as of 05:48, 16 November 2017
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4qf9" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4qf9" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Ionotropic Glutamate Receptors\|Ionotropic Glutamate Receptors]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:08, 7 October 2017

OCA — Sat, 07 Oct 2017 12:08:16 GMT

←Older revision		Revision as of 12:08, 7 October 2017
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4qf9" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4qf9" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Ionotropic Glutamate Receptors\|Ionotropic Glutamate Receptors]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:11, 12 April 2017

OCA — Wed, 12 Apr 2017 12:11:47 GMT

←Older revision		Revision as of 12:11, 12 April 2017
Line 1:		Line 1:
		+
	==Structure of GluK1 ligand-binding domain (S1S2) in complex with (S)-2-amino-4-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)butanoic acid at 2.28 A resolution==		==Structure of GluK1 ligand-binding domain (S1S2) in complex with (S)-2-amino-4-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)butanoic acid at 2.28 A resolution==
	<StructureSection load='4qf9' size='340' side='right' caption='[[4qf9]], [[Resolution\|resolution]] 2.28Å' scene=''>		<StructureSection load='4qf9' size='340' side='right' caption='[[4qf9]], [[Resolution\|resolution]] 2.28Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4qf9]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QF9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QF9 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4qf9]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QF9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QF9 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=35K:(2S)-2-AMINO-4-(2,3-DIOXO-1,2,3,4-TETRAHYDROQUINOXALIN-6-YL)BUTANOIC+ACID'>35K</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=35K:(2S)-2-AMINO-4-(2,3-DIOXO-1,2,3,4-TETRAHYDROQUINOXALIN-6-YL)BUTANOIC+ACID'>35K</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qf9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qf9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qf9 RCSB], [http://www.ebi.ac.uk/pdbsum/4qf9 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qf9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qf9 OCA], [http://pdbe.org/4qf9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qf9 RCSB], [http://www.ebi.ac.uk/pdbsum/4qf9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qf9 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4qf9" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:48, 22 April 2015

OCA — Wed, 22 Apr 2015 12:48:38 GMT

←Older revision		Revision as of 12:48, 22 April 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Structure of GluK1 ligand-binding domain (S1S2) in complex with (S)-2-amino-4-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)butanoic acid at 2.28 A resolution==
		+	<StructureSection load='4qf9' size='340' side='right' caption='[[4qf9]], [[Resolution\|resolution]] 2.28Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4qf9]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QF9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QF9 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=35K:(2S)-2-AMINO-4-(2,3-DIOXO-1,2,3,4-TETRAHYDROQUINOXALIN-6-YL)BUTANOIC+ACID'>35K</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qf9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qf9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qf9 RCSB], [http://www.ebi.ac.uk/pdbsum/4qf9 PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/GRIK1_RAT GRIK1_RAT]] Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.<ref>PMID:16540562</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Two alpha-amino acid-functionalized quinoxalines, 1a (CNG-10301) and 1b (CNG-10300), of a quinoxaline moiety coupled to an amino acid moiety were designed, synthesized, and characterized pharmacologically. While 1a displayed low affinity at native AMPA, KA, and NMDA receptors, and at homomeric GluK1,3 receptors, the affinity for GluK2 was in the midmicromolar range (Ki = 136 muM), 1b displayed low to midmicromolar range binding affinity at all the iGluRs (Ki = 9-126 muM). In functional experiments (outside-out patches excised from transfected HEK293T cells), 100 muM 1a partially blocked GluK1 (33% peak response), while GluK2 was unaffected (96% peak response). Furthermore, 1a was shown not to be an agonist at GluK1 and GluK2 at 100 muM. On the other hand, 100 muM 1b fully antagonized GluK1 (8% peak response) but only partially blocked GluK2 (33% peak response). An X-ray structure at 2.3 A resolution of 1b in the GluK1-LBD (ligand-binding domain) disclosed an unexpected binding mode compared to the predictions made during the design phase; the quinoxaline moiety remains to act as an amino acid bioisostere, but the amino acid moiety is oriented into a new area within the GluK1 receptor. The structure of the GluK1-LBD with 1b showed a large variation in domain openings of the three molecules from 25 degrees to 49 degrees , demonstrating that the GluK1-LBD is capable of undergoing major domain movements.

-	~~The entry 4qf9 is ON HOLD until Paper Publication~~	+	Binding Mode of an alpha-Amino Acid-Linked Quinoxaline-2,3-dione Analogue at Glutamate Receptor Subtype GluK1.,Demmer CS, Moller C, Brown PM, Han L, Pickering DS, Nielsen B, Bowie D, Frydenvang K, Kastrup JS, Bunch L ACS Chem Neurosci. 2015 Apr 9. PMID:25856736<ref>PMID:25856736</ref>

-	~~Authors: Kristensen~~, ~~C.M., Frydenvang, K., Kastrup, J~~.S.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description: Structure~~ of ~~GluK1 ligand-binding domain (S1S2) in complex with (S)-2-amino-4-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)butanoic acid at 2~~.~~28 A resolution~~	+	== References ==
-	~~[[Category: Unreleased Structures]]~~	+	<references/>
-	~~[[Category: Kristensen, C.M]]~~	+	__TOC__
		+	</StructureSection>
	[[Category: Frydenvang, K]]		[[Category: Frydenvang, K]]
-	[[Category: Kastrup, J.S]]	+	[[Category: Kastrup, J S]]
		+	[[Category: Kristensen, C M]]
		+	[[Category: Antagonist]]
		+	[[Category: Gluk1-s1s2]]
		+	[[Category: Kainate receptor ligand-binding domain]]
		+	[[Category: Membrane protein]]

OCA at 15:44, 24 December 2014

OCA — Wed, 24 Dec 2014 15:44:10 GMT

←Older revision		Revision as of 15:44, 24 December 2014
Line 6:		Line 6:

	Description: Structure of GluK1 ligand-binding domain (S1S2) in complex with (S)-2-amino-4-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)butanoic acid at 2.28 A resolution		Description: Structure of GluK1 ligand-binding domain (S1S2) in complex with (S)-2-amino-4-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)butanoic acid at 2.28 A resolution
		+	[[Category: Unreleased Structures]]
		+	[[Category: Kristensen, C.M]]
		+	[[Category: Frydenvang, K]]
		+	[[Category: Kastrup, J.S]]

OCA at 08:09, 24 September 2014

OCA — Wed, 24 Sep 2014 08:09:27 GMT

←Older revision		Revision as of 08:09, 24 September 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4qf9 is ON HOLD	+	The entry 4qf9 is ON HOLD until Paper Publication

	Authors: Kristensen, C.M., Frydenvang, K., Kastrup, J.S.		Authors: Kristensen, C.M., Frydenvang, K., Kastrup, J.S.

	Description: Structure of GluK1 ligand-binding domain (S1S2) in complex with (S)-2-amino-4-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)butanoic acid at 2.28 A resolution		Description: Structure of GluK1 ligand-binding domain (S1S2) in complex with (S)-2-amino-4-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)butanoic acid at 2.28 A resolution

OCA: Protected "4qf9" [edit=sysop:move=sysop]

OCA — Wed, 28 May 2014 08:32:44 GMT

Protected "4qf9" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:32, 28 May 2014