4qgx - Revision history

OCA at 17:32, 20 September 2023

OCA — Wed, 20 Sep 2023 17:32:07 GMT

←Older revision		Revision as of 17:32, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4qgx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QGX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QGX FirstGlance]. <br>		<table><tr><td colspan='2'>[[4qgx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QGX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QGX FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LMC:(2E,4E,6E)-3-METHYL-6-(1,3,3-TRIMETHYL-1,3-DIHYDRO-2H-INDOL-2-YLIDENE)HEXA-2,4-DIENAL'>LMC</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.471Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LMC:(2E,4E,6E)-3-METHYL-6-(1,3,3-TRIMETHYL-1,3-DIHYDRO-2H-INDOL-2-YLIDENE)HEXA-2,4-DIENAL'>LMC</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qgx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qgx OCA], [https://pdbe.org/4qgx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qgx RCSB], [https://www.ebi.ac.uk/pdbsum/4qgx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qgx ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qgx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qgx OCA], [https://pdbe.org/4qgx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qgx RCSB], [https://www.ebi.ac.uk/pdbsum/4qgx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qgx ProSAT]</span></td></tr>
	</table>		</table>

OCA at 11:29, 15 February 2023

OCA — Wed, 15 Feb 2023 11:29:36 GMT

←Older revision		Revision as of 11:29, 15 February 2023
Line 3:		Line 3:
	<StructureSection load='4qgx' size='340' side='right'caption='[[4qgx]], [[Resolution\|resolution]] 1.47Å' scene=''>		<StructureSection load='4qgx' size='340' side='right'caption='[[4qgx]], [[Resolution\|resolution]] 1.47Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4qgx]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QGX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=4QGX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4qgx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QGX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QGX FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LMC:(2E,4E,6E)-3-METHYL-6-(1,3,3-TRIMETHYL-1,3-DIHYDRO-2H-INDOL-2-YLIDENE)HEXA-2,4-DIENAL'>LMC</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LMC:(2E,4E,6E)-3-METHYL-6-(1,3,3-TRIMETHYL-1,3-DIHYDRO-2H-INDOL-2-YLIDENE)HEXA-2,4-DIENAL'>LMC</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4qgw\|4qgw]], [[4qgv\|4qgv]], [[3fep\|3fep]], [[4exz\|4exz]], [[4eej\|4eej]], [[3f8a\|3f8a]], [[2g7b\|2g7b]], [[4i9s\|4i9s]]</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qgx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qgx OCA], [https://pdbe.org/4qgx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qgx RCSB], [https://www.ebi.ac.uk/pdbsum/4qgx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qgx ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CRABP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>~~	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=4qgx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qgx OCA], [~~http~~://pdbe.org/4qgx PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4qgx RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4qgx PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4qgx ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/RABP2_HUMAN RABP2_HUMAN]] Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.	+	[https://www.uniprot.org/uniprot/RABP2_HUMAN RABP2_HUMAN] Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 27:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Geiger~~, J H~~]]	+	[[Category: Geiger JH]]
-	[[Category: Nosrati, M]]	+	[[Category: Nosrati M]]
-	[[Category: Yapici, I]]	+	[[Category: Yapici I]]
-	~~[[Category: Fluorescent protein tag]]~~	+
-	~~[[Category: Merocyanine dyes for fluorescent protein labeling]]~~	+
-	~~[[Category: Merocyanine protonated schiff base iminium]]~~	+
-	~~[[Category: Protein binding]]~~	+
-	~~[[Category: Protein engineering]]~~	+
-	~~[[Category: Protein fluorescence~~]]	+

OCA at 09:44, 9 September 2020

OCA — Wed, 09 Sep 2020 09:44:15 GMT

←Older revision		Revision as of 09:44, 9 September 2020
Line 1:		Line 1:

-	==Crystal ~~sturcture~~ of the R132K:R111L:L121E mutant of Cellular Retinoic Acid Binding ProteinII complexed with a synthetic ligand (Merocyanine) at 1.47 angstrom resolution==	+	==Crystal structure of the R132K:R111L:L121E mutant of Cellular Retinoic Acid Binding ProteinII complexed with a synthetic ligand (Merocyanine) at 1.47 angstrom resolution==
	<StructureSection load='4qgx' size='340' side='right'caption='[[4qgx]], [[Resolution\|resolution]] 1.47Å' scene=''>		<StructureSection load='4qgx' size='340' side='right'caption='[[4qgx]], [[Resolution\|resolution]] 1.47Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4qgx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QGX OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4QGX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4qgx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QGX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4QGX FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LMC:(2E,4E,6E)-3-METHYL-6-(1,3,3-TRIMETHYL-1,3-DIHYDRO-2H-INDOL-2-YLIDENE)HEXA-2,4-DIENAL'>LMC</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LMC:(2E,4E,6E)-3-METHYL-6-(1,3,3-TRIMETHYL-1,3-DIHYDRO-2H-INDOL-2-YLIDENE)HEXA-2,4-DIENAL'>LMC</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4qgw\|4qgw]], [[4qgv\|4qgv]], [[3fep\|3fep]], [[4exz\|4exz]], [[4eej\|4eej]], [[3f8a\|3f8a]], [[2g7b\|2g7b]], [[4i9s\|4i9s]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4qgw\|4qgw]], [[4qgv\|4qgv]], [[3fep\|3fep]], [[4exz\|4exz]], [[4eej\|4eej]], [[3f8a\|3f8a]], [[2g7b\|2g7b]], [[4i9s\|4i9s]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CRABP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CRABP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4qgx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qgx OCA], [http://pdbe.org/4qgx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qgx RCSB], [http://www.ebi.ac.uk/pdbsum/4qgx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qgx ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4qgx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qgx OCA], [http://pdbe.org/4qgx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qgx RCSB], [http://www.ebi.ac.uk/pdbsum/4qgx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qgx ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 22:		Line 22:

	==See Also==		==See Also==
-	*[[Cellular retinoic acid-binding protein\|Cellular retinoic acid-binding protein]]	+	*[[Cellular retinoic acid-binding protein 3D structures\|Cellular retinoic acid-binding protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:08, 24 April 2019

OCA — Wed, 24 Apr 2019 09:08:38 GMT

←Older revision		Revision as of 09:08, 24 April 2019
Line 1:		Line 1:

	==Crystal sturcture of the R132K:R111L:L121E mutant of Cellular Retinoic Acid Binding ProteinII complexed with a synthetic ligand (Merocyanine) at 1.47 angstrom resolution==		==Crystal sturcture of the R132K:R111L:L121E mutant of Cellular Retinoic Acid Binding ProteinII complexed with a synthetic ligand (Merocyanine) at 1.47 angstrom resolution==
-	<StructureSection load='4qgx' size='340' side='right' caption='[[4qgx]], [[Resolution\|resolution]] 1.47Å' scene=''>	+	<StructureSection load='4qgx' size='340' side='right'caption='[[4qgx]], [[Resolution\|resolution]] 1.47Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4qgx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QGX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QGX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4qgx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QGX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QGX FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LMC:(2E,4E,6E)-3-METHYL-6-(1,3,3-TRIMETHYL-1,3-DIHYDRO-2H-INDOL-2-YLIDENE)HEXA-2,4-DIENAL'>LMC</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LMC:(2E,4E,6E)-3-METHYL-6-(1,3,3-TRIMETHYL-1,3-DIHYDRO-2H-INDOL-2-YLIDENE)HEXA-2,4-DIENAL'>LMC</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4qgw\|4qgw]], [[4qgv\|4qgv]], [[3fep\|3fep]], [[4exz\|4exz]], [[4eej\|4eej]], [[3f8a\|3f8a]], [[2g7b\|2g7b]], [[4i9s\|4i9s]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4qgw\|4qgw]], [[4qgv\|4qgv]], [[3fep\|3fep]], [[4exz\|4exz]], [[4eej\|4eej]], [[3f8a\|3f8a]], [[2g7b\|2g7b]], [[4i9s\|4i9s]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CRABP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qgx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qgx OCA], [http://pdbe.org/4qgx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qgx RCSB], [http://www.ebi.ac.uk/pdbsum/4qgx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qgx ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qgx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qgx OCA], [http://pdbe.org/4qgx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qgx RCSB], [http://www.ebi.ac.uk/pdbsum/4qgx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qgx ProSAT]</span></td></tr>
	</table>		</table>
Line 26:		Line 27:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Geiger, J H]]		[[Category: Geiger, J H]]
	[[Category: Nosrati, M]]		[[Category: Nosrati, M]]

OCA at 17:17, 4 January 2017

OCA — Wed, 04 Jan 2017 17:17:05 GMT

←Older revision		Revision as of 17:17, 4 January 2017
Line 1:		Line 1:
		+
	==Crystal sturcture of the R132K:R111L:L121E mutant of Cellular Retinoic Acid Binding ProteinII complexed with a synthetic ligand (Merocyanine) at 1.47 angstrom resolution==		==Crystal sturcture of the R132K:R111L:L121E mutant of Cellular Retinoic Acid Binding ProteinII complexed with a synthetic ligand (Merocyanine) at 1.47 angstrom resolution==
	<StructureSection load='4qgx' size='340' side='right' caption='[[4qgx]], [[Resolution\|resolution]] 1.47Å' scene=''>		<StructureSection load='4qgx' size='340' side='right' caption='[[4qgx]], [[Resolution\|resolution]] 1.47Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LMC:(2E,4E,6E)-3-METHYL-6-(1,3,3-TRIMETHYL-1,3-DIHYDRO-2H-INDOL-2-YLIDENE)HEXA-2,4-DIENAL'>LMC</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LMC:(2E,4E,6E)-3-METHYL-6-(1,3,3-TRIMETHYL-1,3-DIHYDRO-2H-INDOL-2-YLIDENE)HEXA-2,4-DIENAL'>LMC</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4qgw\|4qgw]], [[4qgv\|4qgv]], [[3fep\|3fep]], [[4exz\|4exz]], [[4eej\|4eej]], [[3f8a\|3f8a]], [[2g7b\|2g7b]], [[4i9s\|4i9s]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4qgw\|4qgw]], [[4qgv\|4qgv]], [[3fep\|3fep]], [[4exz\|4exz]], [[4eej\|4eej]], [[3f8a\|3f8a]], [[2g7b\|2g7b]], [[4i9s\|4i9s]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qgx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qgx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qgx RCSB], [http://www.ebi.ac.uk/pdbsum/4qgx PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qgx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qgx OCA], [http://pdbe.org/4qgx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qgx RCSB], [http://www.ebi.ac.uk/pdbsum/4qgx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qgx ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4qgx" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Cellular retinoic acid-binding protein\|Cellular retinoic acid-binding protein]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 16:40, 28 January 2015

OCA — Wed, 28 Jan 2015 16:40:39 GMT

←Older revision		Revision as of 16:40, 28 January 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal sturcture of the R132K:R111L:L121E mutant of Cellular Retinoic Acid Binding ProteinII complexed with a synthetic ligand (Merocyanine) at 1.47 angstrom resolution==
		+	<StructureSection load='4qgx' size='340' side='right' caption='[[4qgx]], [[Resolution\|resolution]] 1.47Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4qgx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QGX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QGX FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LMC:(2E,4E,6E)-3-METHYL-6-(1,3,3-TRIMETHYL-1,3-DIHYDRO-2H-INDOL-2-YLIDENE)HEXA-2,4-DIENAL'>LMC</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4qgw\|4qgw]], [[4qgv\|4qgv]], [[3fep\|3fep]], [[4exz\|4exz]], [[4eej\|4eej]], [[3f8a\|3f8a]], [[2g7b\|2g7b]], [[4i9s\|4i9s]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qgx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qgx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qgx RCSB], [http://www.ebi.ac.uk/pdbsum/4qgx PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RABP2_HUMAN RABP2_HUMAN]] Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Protein reengineering of cellular retinoic acid binding protein II (CRABPII) has yielded a genetically addressable system, capable of binding a profluorophoric chromophore that results in fluorescent protein/chromophore complexes. These complexes exhibit far-red emission, with high quantum efficiencies and brightness and also exhibit excellent pH stability spanning the range of 2-11. In the course of this study, it became evident that single mutations of L121E and R59W were most effective in improving the fluorescent characteristics of CRABPII mutants as well as the kinetics of complex formation. The readily crystallizable nature of these proteins was invaluable to provide clues for the observed spectroscopic behavior that results from single mutation of key residues.

-	~~The entry 4qgx is ON HOLD until Paper Publication~~	+	"Turn-On" Protein Fluorescence: In Situ Formation of Cyanine Dyes.,Yapici I, Lee KS, Berbasova T, Nosrati M, Jia X, Vasileiou C, Wang W, Santos EM, Geiger JH, Borhan B J Am Chem Soc. 2015 Jan 14. PMID:25534273<ref>PMID:25534273</ref>

-	~~Authors: Nosrati~~, M.~~, Yapici, I~~., Geiger, J.H.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description: Crystal sturcture of the R132K:R111L:L121E mutant of Cellular Retinoic Acid Binding ProteinII complexed with a synthetic ligand (Merocyanine) at 1.47 angstrom resolution~~	+	== References ==
-	[[Category: ~~Unreleased Structures~~]]	+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Geiger, J H]]
		+	[[Category: Nosrati, M]]
	[[Category: Yapici, I]]		[[Category: Yapici, I]]
-	[[Category: ~~Geiger, J.H~~]]	+	[[Category: Fluorescent protein tag]]
-	[[Category: ~~Nosrati, M~~]]	+	[[Category: Merocyanine dyes for fluorescent protein labeling]]
		+	[[Category: Merocyanine protonated schiff base iminium]]
		+	[[Category: Protein binding]]
		+	[[Category: Protein engineering]]
		+	[[Category: Protein fluorescence]]

OCA at 15:47, 24 December 2014

OCA — Wed, 24 Dec 2014 15:47:47 GMT

←Older revision		Revision as of 15:47, 24 December 2014
Line 6:		Line 6:

	Description: Crystal sturcture of the R132K:R111L:L121E mutant of Cellular Retinoic Acid Binding ProteinII complexed with a synthetic ligand (Merocyanine) at 1.47 angstrom resolution		Description: Crystal sturcture of the R132K:R111L:L121E mutant of Cellular Retinoic Acid Binding ProteinII complexed with a synthetic ligand (Merocyanine) at 1.47 angstrom resolution
		+	[[Category: Unreleased Structures]]
		+	[[Category: Yapici, I]]
		+	[[Category: Geiger, J.H]]
		+	[[Category: Nosrati, M]]

OCA at 08:05, 11 June 2014

OCA — Wed, 11 Jun 2014 08:05:32 GMT

←Older revision		Revision as of 08:05, 11 June 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4qgx is ON HOLD	+	The entry 4qgx is ON HOLD until Paper Publication

	Authors: Nosrati, M., Yapici, I., Geiger, J.H.		Authors: Nosrati, M., Yapici, I., Geiger, J.H.

	Description: Crystal sturcture of the R132K:R111L:L121E mutant of Cellular Retinoic Acid Binding ProteinII complexed with a synthetic ligand (Merocyanine) at 1.47 angstrom resolution		Description: Crystal sturcture of the R132K:R111L:L121E mutant of Cellular Retinoic Acid Binding ProteinII complexed with a synthetic ligand (Merocyanine) at 1.47 angstrom resolution

OCA: Protected "4qgx" [edit=sysop:move=sysop]

OCA — Wed, 04 Jun 2014 04:58:39 GMT

Protected "4qgx" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:58, 4 June 2014

OCA: New page: '''Unreleased structure''' The entry 4qgx is ON HOLD Authors: Nosrati, M., Yapici, I., Geiger, J.H. Description: Crystal sturcture of the R132K:R111L:L121E mutant of Cellular Retinoic ...

OCA — Wed, 04 Jun 2014 04:58:38 GMT

New page: '''Unreleased structure''' The entry 4qgx is ON HOLD Authors: Nosrati, M., Yapici, I., Geiger, J.H. Description: Crystal sturcture of the R132K:R111L:L121E mutant of Cellular Retinoic ...

New page

'''Unreleased structure'''

The entry 4qgx is ON HOLD

Authors: Nosrati, M., Yapici, I., Geiger, J.H.

Description: Crystal sturcture of the R132K:R111L:L121E mutant of Cellular Retinoic Acid Binding ProteinII complexed with a synthetic ligand (Merocyanine) at 1.47 angstrom resolution