4qqi - Revision history

OCA at 17:35, 20 September 2023

OCA — Wed, 20 Sep 2023 17:35:37 GMT

←Older revision		Revision as of 17:35, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4qqi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QQI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QQI FirstGlance]. <br>		<table><tr><td colspan='2'>[[4qqi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QQI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QQI FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.03Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qqi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qqi OCA], [https://pdbe.org/4qqi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qqi RCSB], [https://www.ebi.ac.uk/pdbsum/4qqi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qqi ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qqi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qqi OCA], [https://pdbe.org/4qqi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qqi RCSB], [https://www.ebi.ac.uk/pdbsum/4qqi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qqi ProSAT]</span></td></tr>
	</table>		</table>

OCA at 13:47, 22 February 2023

OCA — Wed, 22 Feb 2023 13:47:08 GMT

←Older revision		Revision as of 13:47, 22 February 2023
Line 3:		Line 3:
	<StructureSection load='4qqi' size='340' side='right'caption='[[4qqi]], [[Resolution\|resolution]] 2.03Å' scene=''>		<StructureSection load='4qqi' size='340' side='right'caption='[[4qqi]], [[Resolution\|resolution]] 2.03Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4qqi]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QQI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4QQI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4qqi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QQI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QQI FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ANKRA2, ANKRA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qqi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qqi OCA], [https://pdbe.org/4qqi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qqi RCSB], [https://www.ebi.ac.uk/pdbsum/4qqi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qqi ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4qqi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qqi OCA], [~~http~~://pdbe.org/4qqi PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4qqi RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4qqi PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4qqi ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/ANRA2_HUMAN ANRA2_HUMAN]] May facilitate endocytosis by linking megalin to components of the cytoskeleton or endocytic machinery.	+	[https://www.uniprot.org/uniprot/ANRA2_HUMAN ANRA2_HUMAN] May facilitate endocytosis by linking megalin to components of the cytoskeleton or endocytic machinery.
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	Peptide motifs are often used for protein-protein interactions. We have recently demonstrated that ankyrin repeats of ANKRA2 and the paralogous bare lymphocyte syndrome transcription factor RFXANK recognize PxLPxL/I motifs shared by megalin, three histone deacetylases, and RFX5. We show here that that CCDC8 is a major partner of ANKRA2 but not RFXANK in cells. The CCDC8 gene is mutated in 3M syndrome, a short-stature disorder with additional facial and skeletal abnormalities. Two other genes mutated in this syndrome encode CUL7 and OBSL1. While CUL7 is a ubiquitin ligase and OBSL1 associates with the cytoskeleton, little is known about CCDC8. Binding and structural analyses reveal that the ankyrin repeats of ANKRA2 recognize a PxLPxL motif at the C-terminal region of CCDC8. The N-terminal part interacts with OBSL1 to form a CUL7 ligase complex. These results link ANKRA2 unexpectedly to 3M syndrome and suggest novel regulatory mechanisms for histone deacetylases and RFX7.	+
-		+
-	Ankyrin Repeats of ANKRA2 Recognize a PxLPxL Motif on the 3M Syndrome Protein CCDC8.,Nie J, Xu C, Jin J, Aka JA, Tempel W, Nguyen V, You L, Weist R, Min J, Pawson T, Yang XJ Structure. 2015 Feb 26. pii: S0969-2126(15)00046-5. doi:, 10.1016/j.str.2015.02.001. PMID:25752541<ref>PMID:25752541</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 4qqi" style="background-color:#fffaf0;"></div>~~	+

	==See Also==		==See Also==
	*[[Ankyrin 3D structures\|Ankyrin 3D structures]]		*[[Ankyrin 3D structures\|Ankyrin 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Arrowsmith~~, C H~~]]	+	[[Category: Arrowsmith CH]]
-	[[Category: Bountra, C]]	+	[[Category: Bountra C]]
-	[[Category: Dong, A]]	+	[[Category: Dong A]]
-	[[Category: Edwards~~, A M~~]]	+	[[Category: Edwards AM]]
-	[[Category: Mackenzie, F]]	+	[[Category: Mackenzie F]]
-	[[Category: Min, J]]	+	[[Category: Min J]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Tempel W]]
-	[[Category: Tempel, W]]	+	[[Category: Xu C]]
-	[[Category: Xu, C]]	+
-	~~[[Category: Sgc]]~~	+
-	~~[[Category: Structural protein~~]]	+

OCA at 08:38, 24 April 2019

OCA — Wed, 24 Apr 2019 08:38:55 GMT

←Older revision		Revision as of 08:38, 24 April 2019
Line 1:		Line 1:

	==Crystal structure of ANKRA2-RFX7 complex==		==Crystal structure of ANKRA2-RFX7 complex==
-	<StructureSection load='4qqi' size='340' side='right' caption='[[4qqi]], [[Resolution\|resolution]] 2.03Å' scene=''>	+	<StructureSection load='4qqi' size='340' side='right'caption='[[4qqi]], [[Resolution\|resolution]] 2.03Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4qqi]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QQI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QQI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4qqi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QQI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QQI FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ANKRA2, ANKRA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qqi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qqi OCA], [http://pdbe.org/4qqi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qqi RCSB], [http://www.ebi.ac.uk/pdbsum/4qqi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qqi ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qqi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qqi OCA], [http://pdbe.org/4qqi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qqi RCSB], [http://www.ebi.ac.uk/pdbsum/4qqi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qqi ProSAT]</span></td></tr>
	</table>		</table>
Line 18:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 4qqi" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4qqi" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Ankyrin 3D structures\|Ankyrin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]
	[[Category: Bountra, C]]		[[Category: Bountra, C]]

OCA at 18:37, 1 February 2017

OCA — Wed, 01 Feb 2017 18:37:38 GMT

←Older revision		Revision as of 18:37, 1 February 2017
Line 1:		Line 1:
		+
	==Crystal structure of ANKRA2-RFX7 complex==		==Crystal structure of ANKRA2-RFX7 complex==
	<StructureSection load='4qqi' size='340' side='right' caption='[[4qqi]], [[Resolution\|resolution]] 2.03Å' scene=''>		<StructureSection load='4qqi' size='340' side='right' caption='[[4qqi]], [[Resolution\|resolution]] 2.03Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4qqi]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QQI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QQI FirstGlance]. <br>		<table><tr><td colspan='2'>[[4qqi]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QQI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QQI FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qqi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qqi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qqi RCSB], [http://www.ebi.ac.uk/pdbsum/4qqi PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qqi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qqi OCA], [http://pdbe.org/4qqi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qqi RCSB], [http://www.ebi.ac.uk/pdbsum/4qqi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qqi ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4qqi" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:02, 18 March 2015

OCA — Wed, 18 Mar 2015 12:02:00 GMT

←Older revision		Revision as of 12:02, 18 March 2015
Line 8:		Line 8:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/ANRA2_HUMAN ANRA2_HUMAN]] May facilitate endocytosis by linking megalin to components of the cytoskeleton or endocytic machinery.		[[http://www.uniprot.org/uniprot/ANRA2_HUMAN ANRA2_HUMAN]] May facilitate endocytosis by linking megalin to components of the cytoskeleton or endocytic machinery.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Peptide motifs are often used for protein-protein interactions. We have recently demonstrated that ankyrin repeats of ANKRA2 and the paralogous bare lymphocyte syndrome transcription factor RFXANK recognize PxLPxL/I motifs shared by megalin, three histone deacetylases, and RFX5. We show here that that CCDC8 is a major partner of ANKRA2 but not RFXANK in cells. The CCDC8 gene is mutated in 3M syndrome, a short-stature disorder with additional facial and skeletal abnormalities. Two other genes mutated in this syndrome encode CUL7 and OBSL1. While CUL7 is a ubiquitin ligase and OBSL1 associates with the cytoskeleton, little is known about CCDC8. Binding and structural analyses reveal that the ankyrin repeats of ANKRA2 recognize a PxLPxL motif at the C-terminal region of CCDC8. The N-terminal part interacts with OBSL1 to form a CUL7 ligase complex. These results link ANKRA2 unexpectedly to 3M syndrome and suggest novel regulatory mechanisms for histone deacetylases and RFX7.
		+
		+	Ankyrin Repeats of ANKRA2 Recognize a PxLPxL Motif on the 3M Syndrome Protein CCDC8.,Nie J, Xu C, Jin J, Aka JA, Tempel W, Nguyen V, You L, Weist R, Min J, Pawson T, Yang XJ Structure. 2015 Feb 26. pii: S0969-2126(15)00046-5. doi:, 10.1016/j.str.2015.02.001. PMID:25752541<ref>PMID:25752541</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 21:32, 24 December 2014

OCA — Wed, 24 Dec 2014 21:32:56 GMT

←Older revision		Revision as of 21:32, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4qqi]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QQI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QQI FirstGlance]. <br>		<table><tr><td colspan='2'>[[4qqi]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QQI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QQI FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qqi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qqi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qqi RCSB], [http://www.ebi.ac.uk/pdbsum/4qqi PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qqi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qqi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qqi RCSB], [http://www.ebi.ac.uk/pdbsum/4qqi PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ANRA2_HUMAN ANRA2_HUMAN]] May facilitate endocytosis by linking megalin to components of the cytoskeleton or endocytic machinery.
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Arrowsmith, C H.]]	+	[[Category: Arrowsmith, C H]]
-	[[Category: Bountra, C.]]	+	[[Category: Bountra, C]]
-	[[Category: Dong, A.]]	+	[[Category: Dong, A]]
-	[[Category: Edwards, A M.]]	+	[[Category: Edwards, A M]]
-	[[Category: Mackenzie, F.]]	+	[[Category: Mackenzie, F]]
-	[[Category: Min, J.]]	+	[[Category: Min, J]]
-	[[Category: ~~SGC,~~ Structural ~~Genomics Consortium.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Tempel, W.]]	+	[[Category: Tempel, W]]
-	[[Category: Xu, C.]]	+	[[Category: Xu, C]]
	[[Category: Sgc]]		[[Category: Sgc]]
-	[[Category: Structural genomics consortium]]
	[[Category: Structural protein]]		[[Category: Structural protein]]

OCA at 06:14, 4 September 2014

OCA — Thu, 04 Sep 2014 06:14:35 GMT

←Older revision		Revision as of 06:14, 4 September 2014
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Crystal structure of ANKRA2-RFX7 complex==
-		+	<StructureSection load='4qqi' size='340' side='right' caption='[[4qqi]], [[Resolution\|resolution]] 2.03Å' scene=''>
-	~~The entry~~ 4qqi is ~~ON HOLD~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4qqi]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QQI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QQI FirstGlance]. <br>
-	~~Authors~~: ~~Xu, C~~.~~, Tempel, W~~., ~~Dong~~, A.~~, Mackenzie, F~~., ~~Bountra~~, C., Arrowsmith, C.H., ~~Edwards~~, A.M., Min, J., Structural Genomics Consortium ~~(SGC)~~	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene><br>
-		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qqi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qqi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qqi RCSB], [http://www.ebi.ac.uk/pdbsum/4qqi PDBsum]</span></td></tr>
-	~~Description~~: ~~Crystal structure of ANKRA2-RFX7 complex~~	+	<table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Arrowsmith, C H.]]
		+	[[Category: Bountra, C.]]
		+	[[Category: Dong, A.]]
		+	[[Category: Edwards, A M.]]
		+	[[Category: Mackenzie, F.]]
		+	[[Category: Min, J.]]
		+	[[Category: SGC, Structural Genomics Consortium.]]
		+	[[Category: Tempel, W.]]
		+	[[Category: Xu, C.]]
		+	[[Category: Sgc]]
		+	[[Category: Structural genomics consortium]]
		+	[[Category: Structural protein]]

OCA at 07:11, 23 July 2014

OCA — Wed, 23 Jul 2014 07:11:48 GMT

←Older revision		Revision as of 07:11, 23 July 2014
Line 3:		Line 3:
	The entry 4qqi is ON HOLD		The entry 4qqi is ON HOLD

-	Authors: Xu, C., Tempel, W., Dong, A., Mackenzie, F., Bountra, C., Arrowsmith, C. H., Edwards, A. M., Min, J., Structural Genomics Consortium (SGC)	+	Authors: Xu, C., Tempel, W., Dong, A., Mackenzie, F., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)

	Description: Crystal structure of ANKRA2-RFX7 complex		Description: Crystal structure of ANKRA2-RFX7 complex

OCA: Protected "4qqi" [edit=sysop:move=sysop]

OCA — Wed, 09 Jul 2014 06:52:38 GMT

Protected "4qqi" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:52, 9 July 2014

OCA: New page: '''Unreleased structure''' The entry 4qqi is ON HOLD Authors: Xu, C., Tempel, W., Dong, A., Mackenzie, F., Bountra, C., Arrowsmith, C. H., Edwards, A. M., Min, J., Structural Genomics C...

OCA — Wed, 09 Jul 2014 06:52:37 GMT

New page: '''Unreleased structure''' The entry 4qqi is ON HOLD Authors: Xu, C., Tempel, W., Dong, A., Mackenzie, F., Bountra, C., Arrowsmith, C. H., Edwards, A. M., Min, J., Structural Genomics C...

New page

'''Unreleased structure'''

The entry 4qqi is ON HOLD

Authors: Xu, C., Tempel, W., Dong, A., Mackenzie, F., Bountra, C., Arrowsmith, C. H., Edwards, A. M., Min, J., Structural Genomics Consortium (SGC)

Description: Crystal structure of ANKRA2-RFX7 complex