4qva - Revision history

OCA at 08:59, 20 March 2024

OCA — Wed, 20 Mar 2024 08:59:21 GMT

←Older revision		Revision as of 08:59, 20 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4qva]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Norovirus_cat/GIV.2/CU081210E/USA/2010 Norovirus cat/GIV.2/CU081210E/USA/2010]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QVA FirstGlance]. <br>		<table><tr><td colspan='2'>[[4qva]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Norovirus_cat/GIV.2/CU081210E/USA/2010 Norovirus cat/GIV.2/CU081210E/USA/2010]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QVA FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qva OCA], [https://pdbe.org/4qva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qva RCSB], [https://www.ebi.ac.uk/pdbsum/4qva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qva ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.18Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qva OCA], [https://pdbe.org/4qva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qva RCSB], [https://www.ebi.ac.uk/pdbsum/4qva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qva ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/H8YRY9_9CALI H8YRY9_9CALI]		[https://www.uniprot.org/uniprot/H8YRY9_9CALI H8YRY9_9CALI]
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Norovirus infects different animals, including humans, mice, dogs, and cats. Here, we show an X-ray crystal structure of a feline GIV.2 norovirus capsid-protruding (P) domain to 2.35A resolution. The feline GIV.2 P domain was reminiscent of human norovirus P domains, except for a novel P2 subdomain alpha-helix and an extended P1 subdomain interface loop. These new structural features likely obstructed histo-blood group antigens, which are attachment factors for human norovirus, from binding at the equivalent sites on the feline GIV.2 P domain. Additionally, an ELISA showed that the feline GIV.2 was antigenically distinct from a human GII.10 norovirus.
-
-	Structural analysis of a feline norovirus protruding domain.,Singh BK, Glatt S, Ferrer JL, Koromyslova AD, Leuthold MM, Dunder J, Hansman GS Virology. 2015 Jan 1;474:181-5. doi: 10.1016/j.virol.2014.10.028. Epub 2014 Nov, 19. PMID:25463616<ref>PMID:25463616</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4qva" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Virus coat proteins 3D structures\|Virus coat proteins 3D structures]]		*[[Virus coat proteins 3D structures\|Virus coat proteins 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 13:54, 22 February 2023

OCA — Wed, 22 Feb 2023 13:54:08 GMT

←Older revision		Revision as of 13:54, 22 February 2023
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	<StructureSection load='4qva' size='340' side='right'caption='[[4qva]], [[Resolution\|resolution]] 2.18Å' scene=''>		<StructureSection load='4qva' size='340' side='right'caption='[[4qva]], [[Resolution\|resolution]] 2.18Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4qva]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Norovirus_cat/~~giv~~.2/~~cu081210e~~/~~usa~~/2010 Norovirus cat/~~giv~~.2/~~cu081210e~~/~~usa~~/2010]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QVA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4QVA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4qva]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Norovirus_cat/GIV.2/CU081210E/USA/2010 Norovirus cat/GIV.2/CU081210E/USA/2010]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QVA FirstGlance]. <br>
-	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4qv2\|4qv2]], [[4quz\|4quz]]</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qva OCA], [https://pdbe.org/4qva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qva RCSB], [https://www.ebi.ac.uk/pdbsum/4qva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qva ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">JF781268 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1160949 Norovirus cat/GIV.2/CU081210E/USA/2010])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qva OCA], [~~http~~://pdbe.org/4qva PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4qva RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4qva PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4qva ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/H8YRY9_9CALI H8YRY9_9CALI]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 17:		Line 17:
	</div>		</div>
	<div class="pdbe-citations 4qva" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4qva" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Virus coat proteins 3D structures\|Virus coat proteins 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 22:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Norovirus cat/~~giv~~ 2/~~cu081210e~~/~~usa~~/2010]]	+	[[Category: Norovirus cat/GIV 2/CU081210E/USA/2010]]
-	[[Category: Hansman~~, G S~~]]	+	[[Category: Hansman GS]]
-	[[Category: Singh~~, B K]]~~	+	[[Category: Singh BK]]
-	~~[[Category: Feline norovirus]]~~	+
-	~~[[Category: P domain]]~~	+
-	~~[[Category: Protruding domain]]~~	+
-	~~[[Category: Viral capsid protein]]~~	+
-	~~[[Category: Viral protein~~]]	+

OCA at 08:39, 24 April 2019

OCA — Wed, 24 Apr 2019 08:39:13 GMT

←Older revision		Revision as of 08:39, 24 April 2019
Line 1:		Line 1:

	==Unliganded crystal structure of Feline Norovirus P Domain co-crystallized with N-glycolylneuraminic acid==		==Unliganded crystal structure of Feline Norovirus P Domain co-crystallized with N-glycolylneuraminic acid==
-	<StructureSection load='4qva' size='340' side='right' caption='[[4qva]], [[Resolution\|resolution]] 2.18Å' scene=''>	+	<StructureSection load='4qva' size='340' side='right'caption='[[4qva]], [[Resolution\|resolution]] 2.18Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4qva]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QVA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4qva]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Norovirus_cat/giv.2/cu081210e/usa/2010 Norovirus cat/giv.2/cu081210e/usa/2010]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QVA FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4qv2\|4qv2]], [[4quz\|4quz]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4qv2\|4qv2]], [[4quz\|4quz]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">JF781268 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1160949 Norovirus cat/GIV.2/CU081210E/USA/2010])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qva OCA], [http://pdbe.org/4qva PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qva RCSB], [http://www.ebi.ac.uk/pdbsum/4qva PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qva ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qva OCA], [http://pdbe.org/4qva PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qva RCSB], [http://www.ebi.ac.uk/pdbsum/4qva PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qva ProSAT]</span></td></tr>
	</table>		</table>
Line 20:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Norovirus cat/giv 2/cu081210e/usa/2010]]
	[[Category: Hansman, G S]]		[[Category: Hansman, G S]]
	[[Category: Singh, B K]]		[[Category: Singh, B K]]

OCA at 17:01, 4 January 2017

OCA — Wed, 04 Jan 2017 17:01:22 GMT

←Older revision		Revision as of 17:01, 4 January 2017
Line 1:		Line 1:
		+
	==Unliganded crystal structure of Feline Norovirus P Domain co-crystallized with N-glycolylneuraminic acid==		==Unliganded crystal structure of Feline Norovirus P Domain co-crystallized with N-glycolylneuraminic acid==
	<StructureSection load='4qva' size='340' side='right' caption='[[4qva]], [[Resolution\|resolution]] 2.18Å' scene=''>		<StructureSection load='4qva' size='340' side='right' caption='[[4qva]], [[Resolution\|resolution]] 2.18Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4qva]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QVA FirstGlance]. <br>		<table><tr><td colspan='2'>[[4qva]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QVA FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4qv2\|4qv2]], [[4quz\|4quz]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4qv2\|4qv2]], [[4quz\|4quz]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qva RCSB], [http://www.ebi.ac.uk/pdbsum/4qva PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qva OCA], [http://pdbe.org/4qva PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qva RCSB], [http://www.ebi.ac.uk/pdbsum/4qva PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qva ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4qva" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:22, 4 March 2015

OCA — Wed, 04 Mar 2015 11:22:59 GMT

←Older revision		Revision as of 11:22, 4 March 2015
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qva RCSB], [http://www.ebi.ac.uk/pdbsum/4qva PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qva RCSB], [http://www.ebi.ac.uk/pdbsum/4qva PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Norovirus infects different animals, including humans, mice, dogs, and cats. Here, we show an X-ray crystal structure of a feline GIV.2 norovirus capsid-protruding (P) domain to 2.35A resolution. The feline GIV.2 P domain was reminiscent of human norovirus P domains, except for a novel P2 subdomain alpha-helix and an extended P1 subdomain interface loop. These new structural features likely obstructed histo-blood group antigens, which are attachment factors for human norovirus, from binding at the equivalent sites on the feline GIV.2 P domain. Additionally, an ELISA showed that the feline GIV.2 was antigenically distinct from a human GII.10 norovirus.
		+
		+	Structural analysis of a feline norovirus protruding domain.,Singh BK, Glatt S, Ferrer JL, Koromyslova AD, Leuthold MM, Dunder J, Hansman GS Virology. 2015 Jan 1;474:181-5. doi: 10.1016/j.virol.2014.10.028. Epub 2014 Nov, 19. PMID:25463616<ref>PMID:25463616</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 12:55, 19 November 2014

OCA — Wed, 19 Nov 2014 12:55:25 GMT

←Older revision		Revision as of 12:55, 19 November 2014
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Unliganded crystal structure of Feline Norovirus P Domain co-crystallized with N-glycolylneuraminic acid==
-		+	<StructureSection load='4qva' size='340' side='right' caption='[[4qva]], [[Resolution\|resolution]] 2.18Å' scene=''>
-	~~The entry~~ 4qva is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4qva]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QVA FirstGlance]. <br>
-	~~Authors~~: ~~Singh~~, B.K., Hansman, G.S.	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4qv2\|4qv2]], [[4quz\|4quz]]</td></tr>
-		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qva RCSB], [http://www.ebi.ac.uk/pdbsum/4qva PDBsum]</span></td></tr>
-	~~Description~~: ~~Unliganded crystal structure of~~ Feline ~~Norovirus~~ P ~~Domain co-crystallized with N-glycolylneuraminic acid~~	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Hansman, G S]]
		+	[[Category: Singh, B K]]
		+	[[Category: Feline norovirus]]
		+	[[Category: P domain]]
		+	[[Category: Protruding domain]]
		+	[[Category: Viral capsid protein]]
		+	[[Category: Viral protein]]

OCA at 08:17, 24 September 2014

OCA — Wed, 24 Sep 2014 08:17:00 GMT

←Older revision		Revision as of 08:17, 24 September 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4qva is ON HOLD	+	The entry 4qva is ON HOLD until Paper Publication

	Authors: Singh, B.K., Hansman, G.S.		Authors: Singh, B.K., Hansman, G.S.

	Description: Unliganded crystal structure of Feline Norovirus P Domain co-crystallized with N-glycolylneuraminic acid		Description: Unliganded crystal structure of Feline Norovirus P Domain co-crystallized with N-glycolylneuraminic acid

OCA: Protected "4qva" [edit=sysop:move=sysop]

OCA — Wed, 23 Jul 2014 07:14:24 GMT

Protected "4qva" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:14, 23 July 2014

OCA: New page: '''Unreleased structure''' The entry 4qva is ON HOLD Authors: Singh, B.K., Hansman, G.S. Description: Unliganded crystal structure of Feline Norovirus P Domain co-crystallized with N-g...

OCA — Wed, 23 Jul 2014 07:14:23 GMT

New page: '''Unreleased structure''' The entry 4qva is ON HOLD Authors: Singh, B.K., Hansman, G.S. Description: Unliganded crystal structure of Feline Norovirus P Domain co-crystallized with N-g...

New page

'''Unreleased structure'''

The entry 4qva is ON HOLD

Authors: Singh, B.K., Hansman, G.S.

Description: Unliganded crystal structure of Feline Norovirus P Domain co-crystallized with N-glycolylneuraminic acid