4qvg - Revision history

OCA at 15:10, 8 November 2023

OCA — Wed, 08 Nov 2023 15:10:41 GMT

←Older revision		Revision as of 15:10, 8 November 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4qvg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptosporangium_sibiricum Streptosporangium sibiricum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QVG FirstGlance]. <br>		<table><tr><td colspan='2'>[[4qvg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptosporangium_sibiricum Streptosporangium sibiricum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QVG FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qvg OCA], [https://pdbe.org/4qvg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qvg RCSB], [https://www.ebi.ac.uk/pdbsum/4qvg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qvg ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.9Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qvg OCA], [https://pdbe.org/4qvg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qvg RCSB], [https://www.ebi.ac.uk/pdbsum/4qvg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qvg ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 13:54, 22 February 2023

OCA — Wed, 22 Feb 2023 13:54:19 GMT

←Older revision		Revision as of 13:54, 22 February 2023
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	<StructureSection load='4qvg' size='340' side='right'caption='[[4qvg]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='4qvg' size='340' side='right'caption='[[4qvg]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4qvg]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"streptosporangium_sibiricum"_gauze_et_al._1969 "streptosporangium~~ sibiricum~~" gauze et al. 1969~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QVG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4QVG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4qvg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptosporangium_sibiricum Streptosporangium sibiricum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QVG FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">sibL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=457432 "Streptosporangium sibiricum" Gauze et al. 1969])</td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qvg OCA], [https://pdbe.org/4qvg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qvg RCSB], [https://www.ebi.ac.uk/pdbsum/4qvg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qvg ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4qvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qvg OCA], [~~http~~://pdbe.org/4qvg PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4qvg RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4qvg PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4qvg ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/C0LTM6_STRSJ C0LTM6_STRSJ]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Streptosporangium sibiricum gauze et al. 1969]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Chen, S C~~]]	+	[[Category: Streptosporangium sibiricum]]
-	[[Category: Chen~~, Y~~]]	+	[[Category: Chen SC]]
-	[[Category: ~~Huang, C H~~]]	+	[[Category: Chen Y]]
-	[[Category: ~~Liu, J S~~]]	+	[[Category: Huang CH]]
-	[[Category: ~~Yang, C S~~]]	+	[[Category: Liu JS]]
-	[[Category: ~~Methyltransferase]]~~	+	[[Category: Yang CS]]
-	~~[[Category: Transferase~~]]	+

OCA at 09:02, 24 April 2019

OCA — Wed, 24 Apr 2019 09:02:42 GMT

←Older revision		Revision as of 09:02, 24 April 2019
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	==Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in its apo form==		==Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in its apo form==
-	<StructureSection load='4qvg' size='340' side='right' caption='[[4qvg]], [[Resolution\|resolution]] 2.90Å' scene=''>	+	<StructureSection load='4qvg' size='340' side='right'caption='[[4qvg]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4qvg]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QVG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QVG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4qvg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"streptosporangium_sibiricum"_gauze_et_al._1969 "streptosporangium sibiricum" gauze et al. 1969]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QVG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QVG FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qvg OCA], [http://pdbe.org/4qvg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qvg RCSB], [http://www.ebi.ac.uk/pdbsum/4qvg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qvg ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">sibL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=457432 "Streptosporangium sibiricum" Gauze et al. 1969])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qvg OCA], [http://pdbe.org/4qvg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qvg RCSB], [http://www.ebi.ac.uk/pdbsum/4qvg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qvg ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Streptosporangium sibiricum gauze et al. 1969]]
		+	[[Category: Large Structures]]
	[[Category: Chen, S C]]		[[Category: Chen, S C]]
	[[Category: Chen, Y]]		[[Category: Chen, Y]]

OCA at 17:34, 9 March 2017

OCA — Thu, 09 Mar 2017 17:34:35 GMT

←Older revision		Revision as of 17:34, 9 March 2017
Line 1:		Line 1:
		+
	==Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in its apo form==		==Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in its apo form==
	<StructureSection load='4qvg' size='340' side='right' caption='[[4qvg]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='4qvg' size='340' side='right' caption='[[4qvg]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4qvg]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QVG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QVG FirstGlance]. <br>		<table><tr><td colspan='2'>[[4qvg]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QVG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QVG FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qvg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qvg RCSB], [http://www.ebi.ac.uk/pdbsum/4qvg PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qvg OCA], [http://pdbe.org/4qvg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qvg RCSB], [http://www.ebi.ac.uk/pdbsum/4qvg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qvg ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4qvg" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 15:49, 27 May 2015

OCA — Wed, 27 May 2015 15:49:32 GMT

←Older revision		Revision as of 15:49, 27 May 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in its apo form==
		+	<StructureSection load='4qvg' size='340' side='right' caption='[[4qvg]], [[Resolution\|resolution]] 2.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4qvg]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QVG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QVG FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qvg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qvg RCSB], [http://www.ebi.ac.uk/pdbsum/4qvg PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Streptosporangium sibiricum SibL catalyzes the methyl transfer from S-adenosylmethionine (SAM) to 3-hydroxykynurenine (3-HK) to produce S-adenosylhomocysteine (SAH) and 3-hydroxy-4-methyl-kynurenine for sibiromycin biosynthesis. Here, we present the crystal structures of apo-form Ss-SibL, Ss-SibL/SAH binary complex and Ss-SibL/SAH/3-HK ternary complex. Ss-SibL is a homodimer. Each subunit comprises a helical N-terminal domain and a Rossmann-fold C-terminal domain. SAM (or SAH) binding alone results in domain movements, suggesting a two-step catalytic cycle. Analyses of the enzyme-ligand interactions and further mutant studies support a mechanism in which Tyr134 serves as the principal base in the transferase reaction of methyl group from SAM to 3-HK.

-	~~The entry 4qvg is ON HOLD until Paper Publication~~	+	Structure and mechanism of an antibiotics-synthesizing 3-hydroxykynurenine C-methyltransferase.,Chen SC, Huang CH, Lai SJ, Liu JS, Fu PK, Tseng ST, Yang CS, Lai MC, Ko TP, Chen Y Sci Rep. 2015 May 11;5:10100. doi: 10.1038/srep10100. PMID:25960001<ref>PMID:25960001</ref>

-	~~Authors: Liu~~, J.S.~~, Chen, S.C., Huang, C.H., Yang, C.S., Chen, Y~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description: Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in its apo form~~	+	== References ==
-	~~[[Category: Unreleased Structures]]~~	+	<references/>
-	[[Category: ~~Liu~~, J.S]]	+	__TOC__
		+	</StructureSection>
		+	[[Category: Chen, S C]]
	[[Category: Chen, Y]]		[[Category: Chen, Y]]
-	[[Category: Huang, C.H]]	+	[[Category: Huang, C H]]
-	[[Category: ~~Chen~~, S.C]]	+	[[Category: Liu, J S]]
-	[[Category: Yang, C.S]]	+	[[Category: Yang, C S]]
		+	[[Category: Methyltransferase]]
		+	[[Category: Transferase]]

OCA at 16:09, 24 December 2014

OCA — Wed, 24 Dec 2014 16:09:25 GMT

←Older revision		Revision as of 16:09, 24 December 2014
Line 6:		Line 6:

	Description: Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in its apo form		Description: Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in its apo form
		+	[[Category: Unreleased Structures]]
		+	[[Category: Liu, J.S]]
		+	[[Category: Chen, Y]]
		+	[[Category: Huang, C.H]]
		+	[[Category: Chen, S.C]]
		+	[[Category: Yang, C.S]]

OCA at 01:12, 7 August 2014

OCA — Thu, 07 Aug 2014 01:12:02 GMT

←Older revision		Revision as of 01:12, 7 August 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4qvg is ON HOLD	+	The entry 4qvg is ON HOLD until Paper Publication

	Authors: Liu, J.S., Chen, S.C., Huang, C.H., Yang, C.S., Chen, Y.		Authors: Liu, J.S., Chen, S.C., Huang, C.H., Yang, C.S., Chen, Y.

	Description: Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in its apo form		Description: Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in its apo form

OCA at 07:03, 30 July 2014

OCA — Wed, 30 Jul 2014 07:03:32 GMT

←Older revision		Revision as of 07:03, 30 July 2014
Line 3:		Line 3:
	The entry 4qvg is ON HOLD		The entry 4qvg is ON HOLD

-	Authors: Liu, J.S., Chen, S. C., Huang, C. H., Yang, C. S., Chen, Y.	+	Authors: Liu, J.S., Chen, S.C., Huang, C.H., Yang, C.S., Chen, Y.

	Description: Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in its apo form		Description: Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in its apo form

OCA: Protected "4qvg" [edit=sysop:move=sysop]

OCA — Wed, 23 Jul 2014 07:14:36 GMT

Protected "4qvg" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:14, 23 July 2014

OCA: New page: '''Unreleased structure''' The entry 4qvg is ON HOLD Authors: Liu, J.S., Chen, S. C., Huang, C. H., Yang, C. S., Chen, Y. Description: Crystal structure of S-adenosylmethionine-depende...

OCA — Wed, 23 Jul 2014 07:14:35 GMT

New page: '''Unreleased structure''' The entry 4qvg is ON HOLD Authors: Liu, J.S., Chen, S. C., Huang, C. H., Yang, C. S., Chen, Y. Description: Crystal structure of S-adenosylmethionine-depende...

New page

'''Unreleased structure'''

The entry 4qvg is ON HOLD

Authors: Liu, J.S., Chen, S. C., Huang, C. H., Yang, C. S., Chen, Y.

Description: Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in its apo form