4r0v - Revision history

OCA at 17:41, 20 September 2023

OCA — Wed, 20 Sep 2023 17:41:57 GMT

←Older revision		Revision as of 17:41, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4r0v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R0V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R0V FirstGlance]. <br>		<table><tr><td colspan='2'>[[4r0v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R0V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R0V FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARS:ARSENIC'>ARS</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.29Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARS:ARSENIC'>ARS</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r0v OCA], [https://pdbe.org/4r0v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r0v RCSB], [https://www.ebi.ac.uk/pdbsum/4r0v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r0v ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r0v OCA], [https://pdbe.org/4r0v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r0v RCSB], [https://www.ebi.ac.uk/pdbsum/4r0v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r0v ProSAT]</span></td></tr>
	</table>		</table>

OCA at 14:03, 22 February 2023

OCA — Wed, 22 Feb 2023 14:03:45 GMT

←Older revision		Revision as of 14:03, 22 February 2023
Line 1:		Line 1:

	==[FeFe]-hydrogenase Oxygen Inactivation is Initiated by the Modification and Degradation of the H cluster 2Fe Subcluster==		==[FeFe]-hydrogenase Oxygen Inactivation is Initiated by the Modification and Degradation of the H cluster 2Fe Subcluster==
-	<StructureSection load='4r0v' size='340' side='right' caption='[[4r0v]], [[Resolution\|resolution]] 2.29Å' scene=''>	+	<StructureSection load='4r0v' size='340' side='right'caption='[[4r0v]], [[Resolution\|resolution]] 2.29Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4r0v]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Chlre Chlre~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R0V OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4R0V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4r0v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R0V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R0V FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARS:ARSENIC'>ARS</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, ~~<scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARS:ARSENIC'>ARS</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>~~</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r0v OCA], [https://pdbe.org/4r0v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r0v RCSB], [https://www.ebi.ac.uk/pdbsum/4r0v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r0v ProSAT]</span></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3lx4\|3lx4]]~~, ~~[[3c8y\|3c8y]]~~<~~/td></tr>~~	+
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]<~~/~~b></td><td class="sblockDat">CHLREDRAFT_183963, hyd1, hydA, hydA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3055 CHLRE])</td></tr>~~	+
-	~~<tr id='activity~~'>~~<td class="sblockLbl"><b>Activity:~~</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferredoxin_hydrogenase Ferredoxin hydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.12.7.2 1.12.7.2] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4r0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r0v OCA], [~~http~~://pdbe.org/4r0v PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4r0v RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4r0v PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4r0v ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9FYU1_CHLRE Q9FYU1_CHLRE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Chlre~~]]	+	[[Category: Chlamydomonas reinhardtii]]
-	[[Category: ~~Ferredoxin hydrogenase~~]]	+	[[Category: Large Structures]]
-	[[Category: Artz~~, J H~~]]	+	[[Category: Artz JH]]
-	[[Category: Bothner, B]]	+	[[Category: Bothner B]]
-	[[Category: Broderick~~, J B~~]]	+	[[Category: Broderick JB]]
-	[[Category: Ghose, S]]	+	[[Category: Ghose S]]
-	[[Category: Hoffman, A]]	+	[[Category: Hoffman A]]
-	[[Category: King~~, P W~~]]	+	[[Category: King PW]]
-	[[Category: Mulder~~, D W~~]]	+	[[Category: Mulder DW]]
-	[[Category: Peters~~, J W~~]]	+	[[Category: Peters JW]]
-	[[Category: Ratzloff~~, M W~~]]	+	[[Category: Ratzloff MW]]
-	[[Category: Swanson~~, S D~~]]	+	[[Category: Swanson SD]]
-	[[Category: White, S]]	+	[[Category: White S]]
-	[[Category: Zadvornyy~~, O A]]~~	+	[[Category: Zadvornyy OA]]
-	~~[[Category: Cys oxidation]]~~	+
-	~~[[Category: Cysteine-s-dioxide]]~~	+
-	~~[[Category: Fes cluster]]~~	+
-	~~[[Category: H-cluster]]~~	+
-	~~[[Category: Hyda1 monomer]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: S-hydroxycysteine~~]]	+

OCA at 09:00, 22 November 2017

OCA — Wed, 22 Nov 2017 09:00:02 GMT

←Older revision		Revision as of 09:00, 22 November 2017
Line 3:		Line 3:
	<StructureSection load='4r0v' size='340' side='right' caption='[[4r0v]], [[Resolution\|resolution]] 2.29Å' scene=''>		<StructureSection load='4r0v' size='340' side='right' caption='[[4r0v]], [[Resolution\|resolution]] 2.29Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4r0v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R0V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R0V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4r0v]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chlre Chlre]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R0V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R0V FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARS:ARSENIC'>ARS</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARS:ARSENIC'>ARS</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3lx4\|3lx4]], [[3c8y\|3c8y]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3lx4\|3lx4]], [[3c8y\|3c8y]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CHLREDRAFT_183963, hyd1, hydA, hydA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3055 CHLRE])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferredoxin_hydrogenase Ferredoxin hydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.12.7.2 1.12.7.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferredoxin_hydrogenase Ferredoxin hydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.12.7.2 1.12.7.2] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r0v OCA], [http://pdbe.org/4r0v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r0v RCSB], [http://www.ebi.ac.uk/pdbsum/4r0v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r0v ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r0v OCA], [http://pdbe.org/4r0v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r0v RCSB], [http://www.ebi.ac.uk/pdbsum/4r0v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r0v ProSAT]</span></td></tr>
Line 23:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Chlre]]
	[[Category: Ferredoxin hydrogenase]]		[[Category: Ferredoxin hydrogenase]]
	[[Category: Artz, J H]]		[[Category: Artz, J H]]

OCA at 17:32, 18 January 2017

OCA — Wed, 18 Jan 2017 17:32:12 GMT

←Older revision		Revision as of 17:32, 18 January 2017
Line 1:		Line 1:
		+
	==[FeFe]-hydrogenase Oxygen Inactivation is Initiated by the Modification and Degradation of the H cluster 2Fe Subcluster==		==[FeFe]-hydrogenase Oxygen Inactivation is Initiated by the Modification and Degradation of the H cluster 2Fe Subcluster==
	<StructureSection load='4r0v' size='340' side='right' caption='[[4r0v]], [[Resolution\|resolution]] 2.29Å' scene=''>		<StructureSection load='4r0v' size='340' side='right' caption='[[4r0v]], [[Resolution\|resolution]] 2.29Å' scene=''>
Line 7:		Line 8:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3lx4\|3lx4]], [[3c8y\|3c8y]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3lx4\|3lx4]], [[3c8y\|3c8y]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferredoxin_hydrogenase Ferredoxin hydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.12.7.2 1.12.7.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferredoxin_hydrogenase Ferredoxin hydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.12.7.2 1.12.7.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r0v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r0v RCSB], [http://www.ebi.ac.uk/pdbsum/4r0v PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r0v OCA], [http://pdbe.org/4r0v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r0v RCSB], [http://www.ebi.ac.uk/pdbsum/4r0v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r0v ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4r0v" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 16:38, 28 January 2015

OCA — Wed, 28 Jan 2015 16:38:43 GMT

←Older revision		Revision as of 16:38, 28 January 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==[FeFe]-hydrogenase Oxygen Inactivation is Initiated by the Modification and Degradation of the H cluster 2Fe Subcluster==
		+	<StructureSection load='4r0v' size='340' side='right' caption='[[4r0v]], [[Resolution\|resolution]] 2.29Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4r0v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R0V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R0V FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARS:ARSENIC'>ARS</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3lx4\|3lx4]], [[3c8y\|3c8y]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferredoxin_hydrogenase Ferredoxin hydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.12.7.2 1.12.7.2] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r0v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r0v RCSB], [http://www.ebi.ac.uk/pdbsum/4r0v PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The [FeFe]-hydrogenase catalytic site H cluster is a complex iron sulfur cluster assembly that is sensitive to oxygen (O2). The O2 sensitivity is a significant barrier for production of hydrogen as an energy source in water-splitting, oxygenic systems. Oxygen reacts directly with the H cluster, which results in rapid enzyme inactivation and eventual degradation. To investigate the progression of O2-dependent [FeFe]-hydrogenase inactivation and the process of H cluster degradation, the highly O2 sensitive [FeFe]-hydrogenase HydA1 from the green algae Chlamydomonas reinhardtii was exposed to defined concentrations of O2 while monitoring the loss of activity and accompanying changes in H cluster spectroscopic properties. The results indicate that H cluster degradation proceeds through a series of reactions, the extent of which depend on the initial enzyme reduction/oxidation state. The degradation process begins with O2 interacting and reacting with the 2Fe subcluster, leading to degradation of the 2Fe subcluster and leaving an inactive [4Fe-4S] subcluster state. This final inactive degradation product could be reactivated in vitro by incubation with 2Fe subcluster maturation machinery, specifically HydFEG, which was observed by recovery of enzyme activity.

-	~~The entry 4r0v~~ is ~~ON HOLD until Paper Publication~~	+	[FeFe]-hydrogenase oxygen inactivation is initiated at the H cluster 2Fe subcluster.,Swanson KD, Ratzloff MW, Mulder DW, Artz JH, Ghose S, Hoffman A, White S, Zadvornyy OA, Broderick JB, Bothner B, King PW, Peters JW J Am Chem Soc. 2015 Jan 12. PMID:25579778<ref>PMID:25579778</ref>

-	~~Authors: Swanson~~, S.~~D., Ratzloff, M.W., Mulder, D.W., Artz, J.H., Ghose,~~ S.~~, Hoffman, A., White, S., Zadvornyy, O.A., Broderick, J.B., Bothner, B., King, P.W., Peters, J.W~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description: [FeFe]-hydrogenase Oxygen Inactivation is Initiated by the Modification and Degradation of the H cluster 2Fe Subcluster~~	+	== References ==
-	[[Category: ~~Unreleased Structures~~]]	+	<references/>
-	[[Category: ~~Swanson~~, ~~S.D~~]]	+	__TOC__
-	[[Category: ~~King~~, ~~P.W~~]]	+	</StructureSection>
-	[[Category: ~~Ratzloff~~, ~~M.W~~]]	+	[[Category: Ferredoxin hydrogenase]]
		+	[[Category: Artz, J H]]
		+	[[Category: Bothner, B]]
		+	[[Category: Broderick, J B]]
	[[Category: Ghose, S]]		[[Category: Ghose, S]]
		+	[[Category: Hoffman, A]]
		+	[[Category: King, P W]]
		+	[[Category: Mulder, D W]]
		+	[[Category: Peters, J W]]
		+	[[Category: Ratzloff, M W]]
		+	[[Category: Swanson, S D]]
	[[Category: White, S]]		[[Category: White, S]]
-	[[Category: ~~Peters~~, ~~J.W~~]]	+	[[Category: Zadvornyy, O A]]
-	[[Category: ~~Hoffman, A~~]]	+	[[Category: Cys oxidation]]
-	[[Category: ~~Zadvornyy, O.A~~]]	+	[[Category: Cysteine-s-dioxide]]
-	[[Category: ~~Mulder, D.W~~]]	+	[[Category: Fes cluster]]
-	[[Category: ~~Artz, J.~~H]]	+	[[Category: H-cluster]]
-	[[Category: ~~Bothner, B~~]]	+	[[Category: Hyda1 monomer]]
-	[[Category: ~~Broderick, J.B~~]]	+	[[Category: Oxidoreductase]]
		+	[[Category: S-hydroxycysteine]]

OCA at 16:21, 24 December 2014

OCA — Wed, 24 Dec 2014 16:21:04 GMT

←Older revision		Revision as of 16:21, 24 December 2014
Line 6:		Line 6:

	Description: [FeFe]-hydrogenase Oxygen Inactivation is Initiated by the Modification and Degradation of the H cluster 2Fe Subcluster		Description: [FeFe]-hydrogenase Oxygen Inactivation is Initiated by the Modification and Degradation of the H cluster 2Fe Subcluster
		+	[[Category: Unreleased Structures]]
		+	[[Category: Swanson, S.D]]
		+	[[Category: King, P.W]]
		+	[[Category: Ratzloff, M.W]]
		+	[[Category: Ghose, S]]
		+	[[Category: White, S]]
		+	[[Category: Peters, J.W]]
		+	[[Category: Hoffman, A]]
		+	[[Category: Zadvornyy, O.A]]
		+	[[Category: Mulder, D.W]]
		+	[[Category: Artz, J.H]]
		+	[[Category: Bothner, B]]
		+	[[Category: Broderick, J.B]]

OCA at 08:19, 24 September 2014

OCA — Wed, 24 Sep 2014 08:19:35 GMT

←Older revision		Revision as of 08:19, 24 September 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4r0v is ON HOLD	+	The entry 4r0v is ON HOLD until Paper Publication

	Authors: Swanson, S.D., Ratzloff, M.W., Mulder, D.W., Artz, J.H., Ghose, S., Hoffman, A., White, S., Zadvornyy, O.A., Broderick, J.B., Bothner, B., King, P.W., Peters, J.W.		Authors: Swanson, S.D., Ratzloff, M.W., Mulder, D.W., Artz, J.H., Ghose, S., Hoffman, A., White, S., Zadvornyy, O.A., Broderick, J.B., Bothner, B., King, P.W., Peters, J.W.

	Description: [FeFe]-hydrogenase Oxygen Inactivation is Initiated by the Modification and Degradation of the H cluster 2Fe Subcluster		Description: [FeFe]-hydrogenase Oxygen Inactivation is Initiated by the Modification and Degradation of the H cluster 2Fe Subcluster

OCA: Protected "4r0v" [edit=sysop:move=sysop]

OCA — Wed, 13 Aug 2014 07:47:21 GMT

Protected "4r0v" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:47, 13 August 2014

OCA: New page: '''Unreleased structure''' The entry 4r0v is ON HOLD Authors: Swanson, S.D., Ratzloff, M.W., Mulder, D.W., Artz, J.H., Ghose, S., Hoffman, A., White, S., Zadvornyy, O.A., Broderick, J.B...

OCA — Wed, 13 Aug 2014 07:47:19 GMT

New page: '''Unreleased structure''' The entry 4r0v is ON HOLD Authors: Swanson, S.D., Ratzloff, M.W., Mulder, D.W., Artz, J.H., Ghose, S., Hoffman, A., White, S., Zadvornyy, O.A., Broderick, J.B...

New page

'''Unreleased structure'''

The entry 4r0v is ON HOLD

Authors: Swanson, S.D., Ratzloff, M.W., Mulder, D.W., Artz, J.H., Ghose, S., Hoffman, A., White, S., Zadvornyy, O.A., Broderick, J.B., Bothner, B., King, P.W., Peters, J.W.

Description: [FeFe]-hydrogenase Oxygen Inactivation is Initiated by the Modification and Degradation of the H cluster 2Fe Subcluster