4r5u - Revision history

OCA at 06:41, 2 March 2023

OCA — Thu, 02 Mar 2023 06:41:28 GMT

←Older revision		Revision as of 06:41, 2 March 2023
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	==Crystal structure of Rhodostomin R46E mutant==		==Crystal structure of Rhodostomin R46E mutant==
-	<StructureSection load='4r5u' size='340' side='right' caption='[[4r5u]], [[Resolution\|resolution]] 1.81Å' scene=''>	+	<StructureSection load='4r5u' size='340' side='right'caption='[[4r5u]], [[Resolution\|resolution]] 1.81Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4r5u]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Agkistrodon_rhodostoma Agkistrodon~~ rhodostoma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R5U OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4R5U FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4r5u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R5U FirstGlance]. <br>
-	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4r5r\|4r5r]]</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r5u OCA], [https://pdbe.org/4r5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r5u RCSB], [https://www.ebi.ac.uk/pdbsum/4r5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r5u ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RHOD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=8717 Agkistrodon rhodostoma])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4r5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r5u OCA], [~~http~~://pdbe.org/4r5u PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4r5u RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4r5u PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4r5u ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH]] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity). Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).	+	[https://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity). Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).
		+
		+	==See Also==
		+	*[[Disintegrin\|Disintegrin]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Agkistrodon~~ rhodostoma]]	+	[[Category: Calloselasma rhodostoma]]
-	[[Category: ~~Chang, Y T~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Chuang, W J~~]]	+	[[Category: Chang YT]]
-	[[Category: ~~Huang, C H~~]]	+	[[Category: Chuang WJ]]
-	[[Category: ~~Jeng, W Y~~]]	+	[[Category: Huang CH]]
-	[[Category: ~~Shiu, J H~~]]	+	[[Category: Jeng WY]]
-	[[Category: ~~Disintegrin]]~~	+	[[Category: Shiu JH]]
-	~~[[Category: Integrin]]~~	+
-	~~[[Category: Linker region]]~~	+
-	~~[[Category: Rgd motif]]~~	+
-	~~[[Category: Rhodostomin]]~~	+
-	~~[[Category: Toxin~~]]	+

OCA at 09:01, 22 November 2017

OCA — Wed, 22 Nov 2017 09:01:43 GMT

←Older revision		Revision as of 09:01, 22 November 2017
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		+
	==Crystal structure of Rhodostomin R46E mutant==		==Crystal structure of Rhodostomin R46E mutant==
	<StructureSection load='4r5u' size='340' side='right' caption='[[4r5u]], [[Resolution\|resolution]] 1.81Å' scene=''>		<StructureSection load='4r5u' size='340' side='right' caption='[[4r5u]], [[Resolution\|resolution]] 1.81Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4r5u]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R5U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R5U FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4r5u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Agkistrodon_rhodostoma Agkistrodon rhodostoma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R5U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R5U FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4r5r\|4r5r]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4r5r\|4r5r]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r5u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r5u RCSB], [http://www.ebi.ac.uk/pdbsum/4r5u PDBsum]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RHOD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=8717 Agkistrodon rhodostoma])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r5u OCA], [http://pdbe.org/4r5u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r5u RCSB], [http://www.ebi.ac.uk/pdbsum/4r5u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r5u ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 10:		Line 12:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Agkistrodon rhodostoma]]
	[[Category: Chang, Y T]]		[[Category: Chang, Y T]]
	[[Category: Chuang, W J]]		[[Category: Chuang, W J]]

OCA at 13:32, 26 August 2015

OCA — Wed, 26 Aug 2015 13:32:19 GMT

←Older revision		Revision as of 13:32, 26 August 2015
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-	'''~~Unreleased structure~~'''	+	==Crystal structure of Rhodostomin R46E mutant==
-		+	<StructureSection load='4r5u' size='340' side='right' caption='[[4r5u]], [[Resolution\|resolution]] 1.81Å' scene=''>
-	~~The entry~~ 4r5u is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4r5u]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R5U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R5U FirstGlance]. <br>
-	~~Authors~~: ~~Huang, C~~.H.~~, Shiu, J~~.H., ~~Chang, Y~~.T., ~~Jeng, W~~.Y., ~~Chuang, W~~.J.	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4r5r\|4r5r]]</td></tr>
-		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r5u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r5u RCSB], [http://www.ebi.ac.uk/pdbsum/4r5u PDBsum]</span></td></tr>
-	~~Description: Crystal structure of Rhodostomin R46E mutant~~	+	</table>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	== Function ==
-	~~[[Category~~: ~~Jeng~~, W.~~Y]]~~	+	[[http://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH]] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity). Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).
-	[[Category: Chang, Y.T]]	+	__TOC__
-	[[Category: Chuang, W.J]]	+	</StructureSection>
-	[[Category: Huang, C.H]]	+	[[Category: Chang, Y T]]
-	[[Category: Shiu, J.H]]	+	[[Category: Chuang, W J]]
		+	[[Category: Huang, C H]]
		+	[[Category: Jeng, W Y]]
		+	[[Category: Shiu, J H]]
		+	[[Category: Disintegrin]]
		+	[[Category: Integrin]]
		+	[[Category: Linker region]]
		+	[[Category: Rgd motif]]
		+	[[Category: Rhodostomin]]
		+	[[Category: Toxin]]

OCA at 16:31, 24 December 2014

OCA — Wed, 24 Dec 2014 16:31:02 GMT

←Older revision		Revision as of 16:31, 24 December 2014
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	Description: Crystal structure of Rhodostomin R46E mutant		Description: Crystal structure of Rhodostomin R46E mutant
		+	[[Category: Unreleased Structures]]
		+	[[Category: Jeng, W.Y]]
		+	[[Category: Chang, Y.T]]
		+	[[Category: Chuang, W.J]]
		+	[[Category: Huang, C.H]]
		+	[[Category: Shiu, J.H]]

OCA at 08:22, 10 September 2014

OCA — Wed, 10 Sep 2014 08:22:57 GMT

←Older revision		Revision as of 08:22, 10 September 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4r5u is ON HOLD	+	The entry 4r5u is ON HOLD until Paper Publication

	Authors: Huang, C.H., Shiu, J.H., Chang, Y.T., Jeng, W.Y., Chuang, W.J.		Authors: Huang, C.H., Shiu, J.H., Chang, Y.T., Jeng, W.Y., Chuang, W.J.

	Description: Crystal structure of Rhodostomin R46E mutant		Description: Crystal structure of Rhodostomin R46E mutant

OCA: Protected "4r5u" [edit=sysop:move=sysop]

OCA — Wed, 27 Aug 2014 07:03:16 GMT

Protected "4r5u" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:03, 27 August 2014

OCA: New page: '''Unreleased structure''' The entry 4r5u is ON HOLD Authors: Huang, C.H., Shiu, J.H., Chang, Y.T., Jeng, W.Y., Chuang, W.J. Description: Crystal structure of Rhodostomin R46E mutant

OCA — Wed, 27 Aug 2014 07:03:14 GMT

New page: '''Unreleased structure''' The entry 4r5u is ON HOLD Authors: Huang, C.H., Shiu, J.H., Chang, Y.T., Jeng, W.Y., Chuang, W.J. Description: Crystal structure of Rhodostomin R46E mutant

New page

'''Unreleased structure'''

The entry 4r5u is ON HOLD

Authors: Huang, C.H., Shiu, J.H., Chang, Y.T., Jeng, W.Y., Chuang, W.J.

Description: Crystal structure of Rhodostomin R46E mutant