4r64 - Revision history

OCA at 17:44, 20 September 2023

OCA — Wed, 20 Sep 2023 17:44:43 GMT

←Older revision		Revision as of 17:44, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4r64]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R64 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R64 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4r64]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R64 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R64 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r64 OCA], [https://pdbe.org/4r64 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r64 RCSB], [https://www.ebi.ac.uk/pdbsum/4r64 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r64 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r64 OCA], [https://pdbe.org/4r64 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r64 RCSB], [https://www.ebi.ac.uk/pdbsum/4r64 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r64 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 06:41, 2 March 2023

OCA — Thu, 02 Mar 2023 06:41:50 GMT

←Older revision		Revision as of 06:41, 2 March 2023
Line 1:		Line 1:

	==Binary complex crystal structure of E295K mutant of DNA polymerase Beta==		==Binary complex crystal structure of E295K mutant of DNA polymerase Beta==
-	<StructureSection load='4r64' size='340' side='right' caption='[[4r64]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='4r64' size='340' side='right'caption='[[4r64]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4r64]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R64 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4R64 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4r64]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R64 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R64 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4r63\|4r63]], [[4r65\|4r65]], [[4r66\|4r66]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r64 OCA], [https://pdbe.org/4r64 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r64 RCSB], [https://www.ebi.ac.uk/pdbsum/4r64 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r64 ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">POLB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4r64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r64 OCA], [~~http~~://pdbe.org/4r64 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4r64 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4r64 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4r64 ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/DPOLB_HUMAN DPOLB_HUMAN]] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<ref>PMID:9207062</ref> <ref>PMID:9572863</ref> <ref>PMID:11805079</ref> <ref>PMID:21362556</ref>	+	[https://www.uniprot.org/uniprot/DPOLB_HUMAN DPOLB_HUMAN] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<ref>PMID:9207062</ref> <ref>PMID:9572863</ref> <ref>PMID:11805079</ref> <ref>PMID:21362556</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4r64" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4r64" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[DNA polymerase 3D structures\|DNA polymerase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: ~~Batra, V K~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Beard, W A~~]]	+	[[Category: Synthetic construct]]
-	[[Category: ~~Wilson, S H~~]]	+	[[Category: Batra VK]]
-	[[Category: ~~Conformational change~~]]	+	[[Category: Beard WA]]
-	[[Category: ~~Dna polymerase beta]]~~	+	[[Category: Wilson SH]]
-	~~[[Category: Enzyme mechanism]]~~	+
-	~~[[Category: Transferase-dna complex~~]]	+

OCA at 09:01, 22 November 2017

OCA — Wed, 22 Nov 2017 09:01:57 GMT

←Older revision		Revision as of 09:01, 22 November 2017
Line 3:		Line 3:
	<StructureSection load='4r64' size='340' side='right' caption='[[4r64]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='4r64' size='340' side='right' caption='[[4r64]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4r64]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R64 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R64 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4r64]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R64 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R64 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4r63\|4r63]], [[4r65\|4r65]], [[4r66\|4r66]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4r63\|4r63]], [[4r65\|4r65]], [[4r66\|4r66]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">POLB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r64 OCA], [http://pdbe.org/4r64 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r64 RCSB], [http://www.ebi.ac.uk/pdbsum/4r64 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r64 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r64 OCA], [http://pdbe.org/4r64 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r64 RCSB], [http://www.ebi.ac.uk/pdbsum/4r64 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r64 ProSAT]</span></td></tr>
	</table>		</table>
Line 19:		Line 20:
	</div>		</div>
	<div class="pdbe-citations 4r64" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4r64" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[DNA polymerase\|DNA polymerase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Batra, V K]]		[[Category: Batra, V K]]
	[[Category: Beard, W A]]		[[Category: Beard, W A]]

OCA at 07:19, 4 August 2016

OCA — Thu, 04 Aug 2016 07:19:45 GMT

←Older revision		Revision as of 07:19, 4 August 2016
Line 1:		Line 1:
		+
	==Binary complex crystal structure of E295K mutant of DNA polymerase Beta==		==Binary complex crystal structure of E295K mutant of DNA polymerase Beta==
	<StructureSection load='4r64' size='340' side='right' caption='[[4r64]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='4r64' size='340' side='right' caption='[[4r64]], [[Resolution\|resolution]] 2.20Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4r63\|4r63]], [[4r65\|4r65]], [[4r66\|4r66]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4r63\|4r63]], [[4r65\|4r65]], [[4r66\|4r66]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r64 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r64 RCSB], [http://www.ebi.ac.uk/pdbsum/4r64 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r64 OCA], [http://pdbe.org/4r64 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r64 RCSB], [http://www.ebi.ac.uk/pdbsum/4r64 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r64 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4r64" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[DNA polymerase\|DNA polymerase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:51, 25 December 2014

OCA — Thu, 25 Dec 2014 06:51:46 GMT

←Older revision		Revision as of 06:51, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r64 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r64 RCSB], [http://www.ebi.ac.uk/pdbsum/4r64 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r64 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r64 RCSB], [http://www.ebi.ac.uk/pdbsum/4r64 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/DPOLB_HUMAN DPOLB_HUMAN]] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<ref>PMID:9207062</ref> <ref>PMID:9572863</ref> <ref>PMID:11805079</ref> <ref>PMID:21362556</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 05:59, 26 November 2014

OCA — Wed, 26 Nov 2014 05:59:02 GMT

←Older revision		Revision as of 05:59, 26 November 2014
Line 19:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Batra, V K.]]	+	[[Category: Batra, V K]]
-	[[Category: Beard, W A.]]	+	[[Category: Beard, W A]]
-	[[Category: Wilson, S H.]]	+	[[Category: Wilson, S H]]
	[[Category: Conformational change]]		[[Category: Conformational change]]
	[[Category: Dna polymerase beta]]		[[Category: Dna polymerase beta]]
	[[Category: Enzyme mechanism]]		[[Category: Enzyme mechanism]]
	[[Category: Transferase-dna complex]]		[[Category: Transferase-dna complex]]

OCA at 08:37, 20 October 2014

OCA — Mon, 20 Oct 2014 08:37:30 GMT

←Older revision		Revision as of 08:37, 20 October 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r64 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r64 RCSB], [http://www.ebi.ac.uk/pdbsum/4r64 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r64 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r64 RCSB], [http://www.ebi.ac.uk/pdbsum/4r64 PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	DNA polymerases and substrates undergo conformational changes upon forming protein-ligand complexes. These conformational adjustments can hasten or deter DNA synthesis and influence substrate discrimination. From structural comparison of binary DNA and ternary DNA/dNTP complexes of DNA polymerase beta, several side-chains have been implicated in facilitating formation of an active ternary complex poised for chemistry. Site-directed mutagenesis of these highly conserved residues (Asp192, Arg258, Phe272, Glu295, and Tyr296) and kinetic characterization provides insight into the role these residues play during correct and incorrect insertion as well as their role in conformational activation. The catalytic efficiencies for correct nucleotide insertion for alanine mutants was wild type approximately R258A > F272A approximately Y296A > E295A > D192. Since the efficiencies for incorrect insertion was affected to about the same extent for each mutant, effects on fidelity were modest (<5-fold). The R258A mutant exhibited an increase in the single-turnover rate of correct nucleotide insertion. This suggests that the wild-type Arg258 side-chain generates a population of non-productive ternary complexes. Structures of binary and ternary substrate complexes of the R258A mutant and a mutant associated with gastric carcinomas, E295K, provide molecular insight into intermediate structural conformations not appreciated previously. While the R258A mutant crystal structures were similar to wild-type enzyme, the open ternary complex structure of E295K indicates that Arg258 stabilizes a non-productive conformation of the primer terminus that would decrease catalysis. Significantly, the open E295K ternary complex binds two metal ions indicating that metal binding cannot overcome the modified interactions that have interrupted the closure of the N-subdomain.
		+
		+	Substrate-Induced DNA Polymerase beta Activation.,Beard WA, Shock DD, Batra VK, Prasad R, Wilson SH J Biol Chem. 2014 Sep 26. pii: jbc.M114.607432. PMID:25261471<ref>PMID:25261471</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 07:54, 8 October 2014

OCA — Wed, 08 Oct 2014 07:54:45 GMT

←Older revision		Revision as of 07:54, 8 October 2014
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Binary complex crystal structure of E295K mutant of DNA polymerase Beta==
-		+	<StructureSection load='4r64' size='340' side='right' caption='[[4r64]], [[Resolution\|resolution]] 2.20Å' scene=''>
-	~~The entry~~ 4r64 is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4r64]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R64 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R64 FirstGlance]. <br>
-	~~Authors~~: Batra, V.K., Beard, W.A., Wilson, S.H.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4r63\|4r63]], [[4r65\|4r65]], [[4r66\|4r66]]</td></tr>
-	~~Description~~: ~~Binary complex crystal structure of E295K mutant of DNA~~ polymerase ~~Beta~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r64 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r64 RCSB], [http://www.ebi.ac.uk/pdbsum/4r64 PDBsum]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Batra, V K.]]
		+	[[Category: Beard, W A.]]
		+	[[Category: Wilson, S H.]]
		+	[[Category: Conformational change]]
		+	[[Category: Dna polymerase beta]]
		+	[[Category: Enzyme mechanism]]
		+	[[Category: Transferase-dna complex]]

OCA at 08:23, 24 September 2014

OCA — Wed, 24 Sep 2014 08:23:49 GMT

←Older revision		Revision as of 08:23, 24 September 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4r64 is ON HOLD	+	The entry 4r64 is ON HOLD until Paper Publication

	Authors: Batra, V.K., Beard, W.A., Wilson, S.H.		Authors: Batra, V.K., Beard, W.A., Wilson, S.H.

	Description: Binary complex crystal structure of E295K mutant of DNA polymerase Beta		Description: Binary complex crystal structure of E295K mutant of DNA polymerase Beta

OCA at 08:23, 10 September 2014

OCA — Wed, 10 Sep 2014 08:23:10 GMT

←Older revision		Revision as of 08:23, 10 September 2014
Line 3:		Line 3:
	The entry 4r64 is ON HOLD		The entry 4r64 is ON HOLD

-	Authors: Batra, V. K., Beard, W.A., Wilson, S.H.	+	Authors: Batra, V.K., Beard, W.A., Wilson, S.H.

	Description: Binary complex crystal structure of E295K mutant of DNA polymerase Beta		Description: Binary complex crystal structure of E295K mutant of DNA polymerase Beta