4rgq - Revision history

OCA at 17:50, 20 September 2023

OCA — Wed, 20 Sep 2023 17:50:06 GMT

←Older revision		Revision as of 17:50, 20 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4rgq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_DSM_2661 Methanocaldococcus jannaschii DSM 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RGQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RGQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[4rgq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_DSM_2661 Methanocaldococcus jannaschii DSM 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RGQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RGQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=13P:1,3-DIHYDROXYACETONEPHOSPHATE'>13P</scene>, <scene name='pdbligand=1GP:SN-GLYCEROL-1-PHOSPHATE'>1GP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.23Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=13P:1,3-DIHYDROXYACETONEPHOSPHATE'>13P</scene>, <scene name='pdbligand=1GP:SN-GLYCEROL-1-PHOSPHATE'>1GP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rgq OCA], [https://pdbe.org/4rgq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rgq RCSB], [https://www.ebi.ac.uk/pdbsum/4rgq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rgq ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rgq OCA], [https://pdbe.org/4rgq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rgq RCSB], [https://www.ebi.ac.uk/pdbsum/4rgq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rgq ProSAT]</span></td></tr>
	</table>		</table>

OCA at 06:55, 2 March 2023

OCA — Thu, 02 Mar 2023 06:55:22 GMT

←Older revision		Revision as of 06:55, 2 March 2023
Line 1:		Line 1:

	==Crystal structure of the Methanocaldococcus jannaschii G1PDH with NADPH and DHAP==		==Crystal structure of the Methanocaldococcus jannaschii G1PDH with NADPH and DHAP==
-	<StructureSection load='4rgq' size='340' side='right' caption='[[4rgq]], [[Resolution\|resolution]] 2.23Å' scene=''>	+	<StructureSection load='4rgq' size='340' side='right'caption='[[4rgq]], [[Resolution\|resolution]] 2.23Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4rgq]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Metja Metja~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RGQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4RGQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4rgq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_DSM_2661 Methanocaldococcus jannaschii DSM 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RGQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RGQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=13P:1,3-DIHYDROXYACETONEPHOSPHATE'>13P</scene>, <scene name='pdbligand=1GP:SN-GLYCEROL-1-PHOSPHATE'>1GP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=13P:1,3-DIHYDROXYACETONEPHOSPHATE'>13P</scene>, <scene name='pdbligand=1GP:SN-GLYCEROL-1-PHOSPHATE'>1GP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4rfl\|4rfl]], [[4rgv\|4rgv]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rgq OCA], [https://pdbe.org/4rgq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rgq RCSB], [https://www.ebi.ac.uk/pdbsum/4rgq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rgq ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">egsA, MJ0712 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 METJA])</td></tr>	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/sn-glycerol-1-phosphate_dehydrogenase sn-glycerol-1-phosphate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.261 1.1.1.261] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4rgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rgq OCA], [~~http~~://pdbe.org/4rgq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4rgq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4rgq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4rgq ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/G1PDH_METJA G1PDH_METJA]] Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.	+	[https://www.uniprot.org/uniprot/G1PDH_METJA G1PDH_METJA] Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Metja~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Sn-glycerol-1-phosphate dehydrogenase~~]]	+	[[Category: Methanocaldococcus jannaschii DSM 2661]]
-	[[Category: Carbone, V]]	+	[[Category: Carbone V]]
-	[[Category: Ronimus~~, R S~~]]	+	[[Category: Ronimus RS]]
-	[[Category: Schofield~~, L R~~]]	+	[[Category: Schofield LR]]
-	[[Category: Sutherland-Smith~~, A J]]~~	+	[[Category: Sutherland-Smith AJ]]
-	~~[[Category: Dehydrogenase]]~~	+
-	~~[[Category: Metal ion binding]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Rossmann fold]]~~	+
-	~~[[Category: Zn~~]]	+

OCA at 16:09, 16 November 2017

OCA — Thu, 16 Nov 2017 16:09:53 GMT

←Older revision		Revision as of 16:09, 16 November 2017
Line 1:		Line 1:
		+
	==Crystal structure of the Methanocaldococcus jannaschii G1PDH with NADPH and DHAP==		==Crystal structure of the Methanocaldococcus jannaschii G1PDH with NADPH and DHAP==
	<StructureSection load='4rgq' size='340' side='right' caption='[[4rgq]], [[Resolution\|resolution]] 2.23Å' scene=''>		<StructureSection load='4rgq' size='340' side='right' caption='[[4rgq]], [[Resolution\|resolution]] 2.23Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4rgq]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RGQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RGQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4rgq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Metja Metja]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RGQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RGQ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=13P:1,3-DIHYDROXYACETONEPHOSPHATE'>13P</scene>, <scene name='pdbligand=1GP:SN-GLYCEROL-1-PHOSPHATE'>1GP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=13P:1,3-DIHYDROXYACETONEPHOSPHATE'>13P</scene>, <scene name='pdbligand=1GP:SN-GLYCEROL-1-PHOSPHATE'>1GP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4rfl\|4rfl]], [[4rgv\|4rgv]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4rfl\|4rfl]], [[4rgv\|4rgv]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">egsA, MJ0712 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 METJA])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/sn-glycerol-1-phosphate_dehydrogenase sn-glycerol-1-phosphate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.261 1.1.1.261] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/sn-glycerol-1-phosphate_dehydrogenase sn-glycerol-1-phosphate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.261 1.1.1.261] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rgq OCA], [http://pdbe.org/4rgq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rgq RCSB], [http://www.ebi.ac.uk/pdbsum/4rgq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rgq OCA], [http://pdbe.org/4rgq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rgq RCSB], [http://www.ebi.ac.uk/pdbsum/4rgq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rgq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 23:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Metja]]
	[[Category: Sn-glycerol-1-phosphate dehydrogenase]]		[[Category: Sn-glycerol-1-phosphate dehydrogenase]]
	[[Category: Carbone, V]]		[[Category: Carbone, V]]

OCA at 07:31, 30 September 2015

OCA — Wed, 30 Sep 2015 07:31:01 GMT

←Older revision		Revision as of 07:31, 30 September 2015
Line 6:		Line 6:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4rfl\|4rfl]], [[4rgv\|4rgv]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4rfl\|4rfl]], [[4rgv\|4rgv]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/sn-glycerol-1-phosphate_dehydrogenase sn-glycerol-1-phosphate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.261 1.1.1.261] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/sn-glycerol-1-phosphate_dehydrogenase sn-glycerol-1-phosphate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.261 1.1.1.261] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rgq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rgq RCSB], [http://www.ebi.ac.uk/pdbsum/4rgq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rgq OCA], [http://pdbe.org/4rgq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rgq RCSB], [http://www.ebi.ac.uk/pdbsum/4rgq PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4rgq" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:36, 2 September 2015

OCA — Wed, 02 Sep 2015 06:36:40 GMT

←Older revision		Revision as of 06:36, 2 September 2015
Line 10:		Line 10:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/G1PDH_METJA G1PDH_METJA]] Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.		[[http://www.uniprot.org/uniprot/G1PDH_METJA G1PDH_METJA]] Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	One of the most critical events in the origins of cellular life was the development of lipid membranes. Archaea use isoprenoid chains linked via ether bonds to sn-glycerol 1-phosphate (G1P), whereas bacteria and eukaryotes use fatty acids attached via ester bonds to enantiomeric sn-glycerol 3-phosphate. NAD(P)H-dependent G1P dehydrogenase (G1PDH) forms G1P and has been proposed to have played a crucial role in the speciation of the Archaea. We present here, to our knowledge, the first structures of archaeal G1PDH from the hyperthermophilic methanogen Methanocaldococcus jannaschii with bound substrate dihydroxyacetone phosphate, product G1P, NADPH, and Zn(2+) cofactor. We also biochemically characterized the enzyme with respect to pH optimum, cation specificity, and kinetic parameters for dihydroxyacetone phosphate and NAD(P)H. The structures provide key evidence for the reaction mechanism in the stereospecific addition for the NAD(P)H-based pro-R hydrogen transfer and the coordination of the Zn(2+) cofactor during catalysis. Structure-based phylogenetic analyses also provide insight into the origins of G1PDH.
		+
		+	Structure and Evolution of the Archaeal Lipid Synthesis Enzyme sn-Glycerol-1-phosphate Dehydrogenase.,Carbone V, Schofield LR, Zhang Y, Sang C, Dey D, Hannus IM, Martin WF, Sutherland-Smith AJ, Ronimus RS J Biol Chem. 2015 Aug 28;290(35):21690-704. doi: 10.1074/jbc.M115.647461. Epub, 2015 Jul 14. PMID:26175150<ref>PMID:26175150</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 14:14, 22 July 2015

OCA — Wed, 22 Jul 2015 14:14:13 GMT

←Older revision		Revision as of 14:14, 22 July 2015
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Crystal structure of the Methanocaldococcus jannaschii G1PDH with NADPH and DHAP==
-		+	<StructureSection load='4rgq' size='340' side='right' caption='[[4rgq]], [[Resolution\|resolution]] 2.23Å' scene=''>
-	~~The entry~~ 4rgq is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4rgq]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RGQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RGQ FirstGlance]. <br>
-	~~Authors~~: ~~Carbone~~, V., ~~Ronimus~~, ~~R.S.~~, ~~Schofield~~, ~~L.R.~~, ~~Sutherland~~-~~Smith~~, ~~A.J.~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=13P:1,3-DIHYDROXYACETONEPHOSPHATE'>13P</scene>, <scene name='pdbligand=1GP:SN-GLYCEROL-1-PHOSPHATE'>1GP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4rfl\|4rfl]], [[4rgv\|4rgv]]</td></tr>
-	~~Description~~: ~~Crystal structure of the Methanocaldococcus jannaschii G1PDH~~ with ~~NADPH and DHAP~~	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/sn-glycerol-1-phosphate_dehydrogenase sn-glycerol-1-phosphate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.261 1.1.1.261] </span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rgq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rgq RCSB], [http://www.ebi.ac.uk/pdbsum/4rgq PDBsum]</span></td></tr>
-	[[~~Category~~: ~~Ronimus, R~~.S]]	+	</table>
-	[[Category: ~~Schofield, L.R~~]]	+	== Function ==
		+	[[http://www.uniprot.org/uniprot/G1PDH_METJA G1PDH_METJA]] Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Sn-glycerol-1-phosphate dehydrogenase]]
	[[Category: Carbone, V]]		[[Category: Carbone, V]]
-	[[Category: Sutherland-Smith, A.J]]	+	[[Category: Ronimus, R S]]
		+	[[Category: Schofield, L R]]
		+	[[Category: Sutherland-Smith, A J]]
		+	[[Category: Dehydrogenase]]
		+	[[Category: Metal ion binding]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Rossmann fold]]
		+	[[Category: Zn]]

OCA at 16:51, 24 December 2014

OCA — Wed, 24 Dec 2014 16:51:37 GMT

←Older revision		Revision as of 16:51, 24 December 2014
Line 6:		Line 6:

	Description: Crystal structure of the Methanocaldococcus jannaschii G1PDH with NADPH and DHAP		Description: Crystal structure of the Methanocaldococcus jannaschii G1PDH with NADPH and DHAP
		+	[[Category: Unreleased Structures]]
		+	[[Category: Ronimus, R.S]]
		+	[[Category: Schofield, L.R]]
		+	[[Category: Carbone, V]]
		+	[[Category: Sutherland-Smith, A.J]]

OCA at 09:28, 20 October 2014

OCA — Mon, 20 Oct 2014 09:28:06 GMT

←Older revision		Revision as of 09:28, 20 October 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4rgq is ON HOLD	+	The entry 4rgq is ON HOLD until Paper Publication

-	Authors: Carbone, V. , Ronimus, R. S. , Schofield, L. R. , Sutherland-Smith, A. J.	+	Authors: Carbone, V., Ronimus, R.S., Schofield, L.R., Sutherland-Smith, A.J.

	Description: Crystal structure of the Methanocaldococcus jannaschii G1PDH with NADPH and DHAP		Description: Crystal structure of the Methanocaldococcus jannaschii G1PDH with NADPH and DHAP

OCA: Protected "4rgq" [edit=sysop:move=sysop]

OCA — Wed, 08 Oct 2014 06:34:35 GMT

Protected "4rgq" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:34, 8 October 2014

OCA: New page: '''Unreleased structure''' The entry 4rgq is ON HOLD Authors: Carbone, V. , Ronimus, R. S. , Schofield, L. R. , Sutherland-Smith, A. J. Description: Crystal structure of the Methanocal...

OCA — Wed, 08 Oct 2014 06:34:34 GMT

New page: '''Unreleased structure''' The entry 4rgq is ON HOLD Authors: Carbone, V. , Ronimus, R. S. , Schofield, L. R. , Sutherland-Smith, A. J. Description: Crystal structure of the Methanocal...

New page

'''Unreleased structure'''

The entry 4rgq is ON HOLD

Authors: Carbone, V. , Ronimus, R. S. , Schofield, L. R. , Sutherland-Smith, A. J.

Description: Crystal structure of the Methanocaldococcus jannaschii G1PDH with NADPH and DHAP