4rph - Revision history

OCA at 17:53, 20 September 2023

OCA — Wed, 20 Sep 2023 17:53:24 GMT

←Older revision		Revision as of 17:53, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4rph]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RPH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RPH FirstGlance]. <br>		<table><tr><td colspan='2'>[[4rph]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RPH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RPH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GDU:GALACTOSE-URIDINE-5-DIPHOSPHATE'>GDU</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.6Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GDU:GALACTOSE-URIDINE-5-DIPHOSPHATE'>GDU</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rph OCA], [https://pdbe.org/4rph PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rph RCSB], [https://www.ebi.ac.uk/pdbsum/4rph PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rph ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rph OCA], [https://pdbe.org/4rph PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rph RCSB], [https://www.ebi.ac.uk/pdbsum/4rph PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rph ProSAT]</span></td></tr>
	</table>		</table>

OCA at 08:23, 8 March 2023

OCA — Wed, 08 Mar 2023 08:23:09 GMT

←Older revision		Revision as of 08:23, 8 March 2023
Line 1:		Line 1:

	==Crystal structure of Micobacterium tuberculosis UDP-Galactopyranose mutase in complex with substrate UDP-Galp (reduced)==		==Crystal structure of Micobacterium tuberculosis UDP-Galactopyranose mutase in complex with substrate UDP-Galp (reduced)==
-	<StructureSection load='4rph' size='340' side='right' caption='[[4rph]], [[Resolution\|resolution]] 2.60Å' scene=''>	+	<StructureSection load='4rph' size='340' side='right'caption='[[4rph]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4rph]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Myctu Myctu~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RPH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4RPH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4rph]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RPH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RPH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GDU:GALACTOSE-URIDINE-5-DIPHOSPHATE'>GDU</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GDU:GALACTOSE-URIDINE-5-DIPHOSPHATE'>GDU</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v0j\|1v0j]], [[4rpg\|4rpg]], [[4rpj\|4rpj]], [[4rpk\|4rpk]], [[4rpl\|4rpl]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rph OCA], [https://pdbe.org/4rph PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rph RCSB], [https://www.ebi.ac.uk/pdbsum/4rph PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rph ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glf, glfA, Rv3809c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-galactopyranose_mutase UDP-galactopyranose mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.9 5.4.99.9] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4rph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rph OCA], [~~http~~://pdbe.org/4rph PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4rph RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4rph PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4rph ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/GLF_MYCTU GLF_MYCTU]] Catalyzes the interconversion through a 2-keto intermediate of uridine diphosphogalactopyranose (UDP-GalP) into uridine diphosphogalactofuranose (UDP-GalF) which is a key building block for cell wall construction in Mycobacterium tuberculosis.<ref>PMID:9692181</ref>	+	[https://www.uniprot.org/uniprot/GLF_MYCTU GLF_MYCTU] Catalyzes the interconversion through a 2-keto intermediate of uridine diphosphogalactopyranose (UDP-GalP) into uridine diphosphogalactofuranose (UDP-GalF) which is a key building block for cell wall construction in Mycobacterium tuberculosis.<ref>PMID:9692181</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4rph" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4rph" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[UDP-galactopyranose mutase 3D structures\|UDP-galactopyranose mutase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Myctu~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~UDP-galactopyranose mutase~~]]	+	[[Category: Mycobacterium tuberculosis H37Rv]]
-	[[Category: Sanders~~, D A.R~~]]	+	[[Category: Sanders DAR]]
-	[[Category: Straaten~~, K E.Van]]~~	+	[[Category: Van Straaten KE]]
-	~~[[Category: Fad]]~~	+
-	~~[[Category: Flavoenzyme]]~~	+
-	~~[[Category: Isomerase]]~~	+
-	~~[[Category: Mtugm]]~~	+
-	~~[[Category: Udp-galactopyranose mutase~~]]	+

OCA at 09:08, 22 November 2017

OCA — Wed, 22 Nov 2017 09:08:02 GMT

←Older revision		Revision as of 09:08, 22 November 2017
Line 3:		Line 3:
	<StructureSection load='4rph' size='340' side='right' caption='[[4rph]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='4rph' size='340' side='right' caption='[[4rph]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4rph]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RPH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RPH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4rph]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RPH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RPH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GDU:GALACTOSE-URIDINE-5-DIPHOSPHATE'>GDU</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GDU:GALACTOSE-URIDINE-5-DIPHOSPHATE'>GDU</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[~~1voj~~\|~~1voj~~]], [[4rpg\|4rpg]], [[4rpj\|4rpj]], [[4rpk\|4rpk]], [[4rpl\|4rpl]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v0j\|1v0j]], [[4rpg\|4rpg]], [[4rpj\|4rpj]], [[4rpk\|4rpk]], [[4rpl\|4rpl]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glf, glfA, Rv3809c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-galactopyranose_mutase UDP-galactopyranose mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.9 5.4.99.9] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-galactopyranose_mutase UDP-galactopyranose mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.9 5.4.99.9] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rph OCA], [http://pdbe.org/4rph PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rph RCSB], [http://www.ebi.ac.uk/pdbsum/4rph PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rph ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rph OCA], [http://pdbe.org/4rph PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rph RCSB], [http://www.ebi.ac.uk/pdbsum/4rph PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rph ProSAT]</span></td></tr>
Line 20:		Line 21:
	</div>		</div>
	<div class="pdbe-citations 4rph" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4rph" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[UDP-galactopyranose mutase\|UDP-galactopyranose mutase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Myctu]]
	[[Category: UDP-galactopyranose mutase]]		[[Category: UDP-galactopyranose mutase]]
	[[Category: Sanders, D A.R]]		[[Category: Sanders, D A.R]]

OCA at 17:26, 18 January 2017

OCA — Wed, 18 Jan 2017 17:26:19 GMT

←Older revision		Revision as of 17:26, 18 January 2017
Line 1:		Line 1:
		+
	==Crystal structure of Micobacterium tuberculosis UDP-Galactopyranose mutase in complex with substrate UDP-Galp (reduced)==		==Crystal structure of Micobacterium tuberculosis UDP-Galactopyranose mutase in complex with substrate UDP-Galp (reduced)==
	<StructureSection load='4rph' size='340' side='right' caption='[[4rph]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='4rph' size='340' side='right' caption='[[4rph]], [[Resolution\|resolution]] 2.60Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1voj\|1voj]], [[4rpg\|4rpg]], [[4rpj\|4rpj]], [[4rpk\|4rpk]], [[4rpl\|4rpl]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1voj\|1voj]], [[4rpg\|4rpg]], [[4rpj\|4rpj]], [[4rpk\|4rpk]], [[4rpl\|4rpl]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-galactopyranose_mutase UDP-galactopyranose mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.9 5.4.99.9] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-galactopyranose_mutase UDP-galactopyranose mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.9 5.4.99.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rph OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rph RCSB], [http://www.ebi.ac.uk/pdbsum/4rph PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rph OCA], [http://pdbe.org/4rph PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rph RCSB], [http://www.ebi.ac.uk/pdbsum/4rph PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rph ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4rph" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[UDP-galactopyranose mutase\|UDP-galactopyranose mutase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 16:45, 21 January 2015

OCA — Wed, 21 Jan 2015 16:45:23 GMT

←Older revision		Revision as of 16:45, 21 January 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal structure of Micobacterium tuberculosis UDP-Galactopyranose mutase in complex with substrate UDP-Galp (reduced)==
		+	<StructureSection load='4rph' size='340' side='right' caption='[[4rph]], [[Resolution\|resolution]] 2.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4rph]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RPH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RPH FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GDU:GALACTOSE-URIDINE-5-DIPHOSPHATE'>GDU</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1voj\|1voj]], [[4rpg\|4rpg]], [[4rpj\|4rpj]], [[4rpk\|4rpk]], [[4rpl\|4rpl]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-galactopyranose_mutase UDP-galactopyranose mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.9 5.4.99.9] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rph OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rph RCSB], [http://www.ebi.ac.uk/pdbsum/4rph PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/GLF_MYCTU GLF_MYCTU]] Catalyzes the interconversion through a 2-keto intermediate of uridine diphosphogalactopyranose (UDP-GalP) into uridine diphosphogalactofuranose (UDP-GalF) which is a key building block for cell wall construction in Mycobacterium tuberculosis.<ref>PMID:9692181</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	UDP-Galactopyranose mutase (UGM) is a flavin-containing enzyme that catalyzes the reversible conversion of UDP-galactopyranose (UDP-Galp) to UDP-galactofuranose (UDP-Galf) and plays a key role in the biosynthesis of the mycobacterial cell wall galactofuran. A soluble, active form of UGM from Mycobacterium tuberculosis (MtUGM) was obtained from a dual His6-MBP-tagged MtUGM construct. We present the first complex structures of MtUGM with bound substrate UDP-Galp (both oxidized flavin and reduced flavin). In addition, we have determined the complex structures of MtUGM with inhibitors (UDP and the dideoxy-tetrafluorinated analogues of both UDP-Galp (UDP-F4-Galp) and UDP-Galf (UDP-F4-Galf)), which represent the first complex structures of UGM with an analogue in the furanose form, as well as the first structures of dideoxy-tetrafluorinated sugar analogues bound to a protein. These structures provide detailed insight into ligand recognition by MtUGM and show an overall binding mode similar to those reported for other prokaryotic UGMs. The binding of the ligand induces conformational changes in the enzyme, allowing ligand binding and active-site closure. In addition, the complex structure of MtUGM with UDP-F4-Galf reveals the first detailed insight into how the furanose moiety binds to UGM. In particular, this study confirmed that the furanoside adopts a high-energy conformation (4E) within the catalytic pocket. Moreover, these investigations provide structural insights into the enhanced binding of the dideoxy-tetrafluorinated sugars compared to unmodified analogues. These results will help in the design of carbohydrate mimetics and drug development, and show the enormous possibilities for the use of polyfluorination in the design of carbohydrate mimetics.

-	~~The entry 4rph is ON HOLD until Paper Publication~~	+	Structural Basis of Ligand Binding to UDP-Galactopyranose Mutase from Mycobacterium tuberculosis Using Substrate and Tetrafluorinated Substrate Analogues.,van Straaten KE, Kuttiyatveetil JR, Sevrain CM, Villaume SA, Jimenez-Barbero J, Linclau B, Vincent SP, Sanders DA J Am Chem Soc. 2015 Jan 16. PMID:25562380<ref>PMID:25562380</ref>

-	~~Authors: Van Straaten~~, K.E.~~, Sanders, D.A.R~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Crystal structure of Micobacterium tuberculosis~~ UDP-~~Galactopyranose~~ mutase ~~in complex with substrate UDP-Galp (reduced)~~	+	== References ==
-	[[Category: ~~Unreleased Structures~~]]	+	<references/>
-	[[Category: ~~Van~~ Straaten, K.E]]	+	__TOC__
-	[[Category: ~~Sanders, D.A.R~~]]	+	</StructureSection>
		+	[[Category: UDP-galactopyranose mutase]]
		+	[[Category: Sanders, D A.R]]
		+	[[Category: Straaten, K E.Van]]
		+	[[Category: Fad]]
		+	[[Category: Flavoenzyme]]
		+	[[Category: Isomerase]]
		+	[[Category: Mtugm]]
		+	[[Category: Udp-galactopyranose mutase]]

OCA at 17:10, 24 December 2014

OCA — Wed, 24 Dec 2014 17:10:13 GMT

←Older revision		Revision as of 17:10, 24 December 2014
Line 6:		Line 6:

	Description: Crystal structure of Micobacterium tuberculosis UDP-Galactopyranose mutase in complex with substrate UDP-Galp (reduced)		Description: Crystal structure of Micobacterium tuberculosis UDP-Galactopyranose mutase in complex with substrate UDP-Galp (reduced)
		+	[[Category: Unreleased Structures]]
		+	[[Category: Van Straaten, K.E]]
		+	[[Category: Sanders, D.A.R]]

OCA at 11:28, 19 November 2014

OCA — Wed, 19 Nov 2014 11:28:50 GMT

←Older revision		Revision as of 11:28, 19 November 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4rph is ON HOLD	+	The entry 4rph is ON HOLD until Paper Publication

	Authors: Van Straaten, K.E., Sanders, D.A.R.		Authors: Van Straaten, K.E., Sanders, D.A.R.

	Description: Crystal structure of Micobacterium tuberculosis UDP-Galactopyranose mutase in complex with substrate UDP-Galp (reduced)		Description: Crystal structure of Micobacterium tuberculosis UDP-Galactopyranose mutase in complex with substrate UDP-Galp (reduced)

OCA: Protected "4rph" [edit=sysop:move=sysop]

OCA — Wed, 05 Nov 2014 07:43:23 GMT

Protected "4rph" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:43, 5 November 2014

OCA: New page: '''Unreleased structure''' The entry 4rph is ON HOLD Authors: Van Straaten, K.E., Sanders, D.A.R. Description: Crystal structure of Micobacterium tuberculosis UDP-Galactopyranose mutas...

OCA — Wed, 05 Nov 2014 07:43:21 GMT

New page: '''Unreleased structure''' The entry 4rph is ON HOLD Authors: Van Straaten, K.E., Sanders, D.A.R. Description: Crystal structure of Micobacterium tuberculosis UDP-Galactopyranose mutas...

New page

'''Unreleased structure'''

The entry 4rph is ON HOLD

Authors: Van Straaten, K.E., Sanders, D.A.R.

Description: Crystal structure of Micobacterium tuberculosis UDP-Galactopyranose mutase in complex with substrate UDP-Galp (reduced)