4run - Revision history

OCA at 17:56, 20 September 2023

OCA — Wed, 20 Sep 2023 17:56:09 GMT

←Older revision		Revision as of 17:56, 20 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4run]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RUN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RUN FirstGlance]. <br>		<table><tr><td colspan='2'>[[4run]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RUN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RUN FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.6Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4run FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4run OCA], [https://pdbe.org/4run PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4run RCSB], [https://www.ebi.ac.uk/pdbsum/4run PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4run ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4run FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4run OCA], [https://pdbe.org/4run PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4run RCSB], [https://www.ebi.ac.uk/pdbsum/4run PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4run ProSAT]</span></td></tr>
	</table>		</table>

OCA at 08:28, 8 March 2023

OCA — Wed, 08 Mar 2023 08:28:48 GMT

←Older revision		Revision as of 08:28, 8 March 2023
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	==Crystal structure of human odorant binding protein OBPIIa==		==Crystal structure of human odorant binding protein OBPIIa==
-	<StructureSection load='4run' size='340' side='right' caption='[[4run]], [[Resolution\|resolution]] 2.60Å' scene=''>	+	<StructureSection load='4run' size='340' side='right'caption='[[4run]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4run]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RUN OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4RUN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4run]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RUN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RUN FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">OBP2A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4run FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4run OCA], [https://pdbe.org/4run PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4run RCSB], [https://www.ebi.ac.uk/pdbsum/4run PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4run ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4run FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4run OCA], [~~http~~://pdbe.org/4run PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4run RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4run PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4run ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/OBP2A_HUMAN OBP2A_HUMAN]] Probably binds and transports small hydrophobic volatile molecules with a higher affinity for aldehydes and large fatty acids.<ref>PMID:12044155</ref>	+	[https://www.uniprot.org/uniprot/OBP2A_HUMAN OBP2A_HUMAN] Probably binds and transports small hydrophobic volatile molecules with a higher affinity for aldehydes and large fatty acids.<ref>PMID:12044155</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 4run" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4run" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Odorant binding protein 3D structures\|Odorant binding protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: ~~Schiefner, A~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Skerra,~~ A]]	+	[[Category: Schiefner A]]
-	[[Category: ~~Aliphatic aldehyde]]~~	+	[[Category: Skerra A]]
-	~~[[Category: Fatty acid]]~~	+
-	~~[[Category: Human lipocalin]]~~	+
-	~~[[Category: Lilial]]~~	+
-	~~[[Category: Lipid binding protein]]~~	+
-	~~[[Category: Nasal mucus]]~~	+
-	~~[[Category: Odorant-binding protein]]~~	+
-	~~[[Category: Transport protein]]~~	+
-	~~[[Category: Vanillin~~]]	+

OCA at 09:10, 22 November 2017

OCA — Wed, 22 Nov 2017 09:10:19 GMT

←Older revision		Revision as of 09:10, 22 November 2017
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	<StructureSection load='4run' size='340' side='right' caption='[[4run]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='4run' size='340' side='right' caption='[[4run]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4run]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RUN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RUN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4run]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RUN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RUN FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">OBP2A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4run FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4run OCA], [http://pdbe.org/4run PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4run RCSB], [http://www.ebi.ac.uk/pdbsum/4run PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4run ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4run FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4run OCA], [http://pdbe.org/4run PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4run RCSB], [http://www.ebi.ac.uk/pdbsum/4run PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4run ProSAT]</span></td></tr>
	</table>		</table>
Line 18:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 4run" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4run" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Odorant binding protein\|Odorant binding protein]]
-	*[[Odorant binding protein 3D structures\|Odorant binding protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Schiefner, A]]		[[Category: Schiefner, A]]
	[[Category: Skerra, A]]		[[Category: Skerra, A]]

OCA at 02:01, 11 March 2017

OCA — Sat, 11 Mar 2017 02:01:32 GMT

←Older revision		Revision as of 02:01, 11 March 2017
Line 1:		Line 1:
		+
	==Crystal structure of human odorant binding protein OBPIIa==		==Crystal structure of human odorant binding protein OBPIIa==
	<StructureSection load='4run' size='340' side='right' caption='[[4run]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='4run' size='340' side='right' caption='[[4run]], [[Resolution\|resolution]] 2.60Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4run]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RUN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RUN FirstGlance]. <br>		<table><tr><td colspan='2'>[[4run]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RUN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RUN FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4run FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4run OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4run RCSB], [http://www.ebi.ac.uk/pdbsum/4run PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4run FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4run OCA], [http://pdbe.org/4run PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4run RCSB], [http://www.ebi.ac.uk/pdbsum/4run PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4run ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4run" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
		+	*[[Odorant binding protein\|Odorant binding protein]]
	*[[Odorant binding protein 3D structures\|Odorant binding protein 3D structures]]		*[[Odorant binding protein 3D structures\|Odorant binding protein 3D structures]]
	== References ==		== References ==

OCA at 07:27, 10 June 2015

OCA — Wed, 10 Jun 2015 07:27:40 GMT

←Older revision		Revision as of 07:27, 10 June 2015
Line 16:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+
		+	==See Also==
		+	*[[Odorant binding protein 3D structures\|Odorant binding protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:02, 8 April 2015

OCA — Wed, 08 Apr 2015 11:02:20 GMT

←Older revision		Revision as of 11:02, 8 April 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal structure of human odorant binding protein OBPIIa==
		+	<StructureSection load='4run' size='340' side='right' caption='[[4run]], [[Resolution\|resolution]] 2.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4run]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RUN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RUN FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4run FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4run OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4run RCSB], [http://www.ebi.ac.uk/pdbsum/4run PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/OBP2A_HUMAN OBP2A_HUMAN]] Probably binds and transports small hydrophobic volatile molecules with a higher affinity for aldehydes and large fatty acids.<ref>PMID:12044155</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Human odorant-binding protein, OBPIIa , is expressed by nasal epithelia to facilitate transport of hydrophobic odorant molecules across the aqueous mucus. Here, we report its crystallographic analysis at 2.6 A resolution. OBPIIa is a monomeric protein that exhibits the classical lipocalin fold with a conserved eight-stranded beta-barrel harboring a remarkably large hydrophobic pocket. Basic residues within the four loops that shape the entrance to this ligand-binding site evoke a positive electrostatic potential. Human OBPIIa shows distinct features compared with other mammalian OBPs, including a potentially reactive Cys side chain within its pocket similar to human tear lipocalin. Proteins 2015. (c) 2015 Wiley Periodicals, Inc.

-	~~The entry 4run is ON HOLD until Paper Publication~~	+	Crystal structure of the human odorant binding protein, OBP.,Schiefner A, Freier R, Eichinger A, Skerra A Proteins. 2015 Mar 21. doi: 10.1002/prot.24797. PMID:25810031<ref>PMID:25810031</ref>

-	~~Authors: Schiefner~~, A.~~, Skerra, A~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description: Crystal structure of human odorant binding protein OBPIIa~~	+	== References ==
-	[[Category: ~~Unreleased Structures~~]]	+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Schiefner, A]]
	[[Category: Skerra, A]]		[[Category: Skerra, A]]
-	[[Category: ~~Schiefner, A~~]]	+	[[Category: Aliphatic aldehyde]]
		+	[[Category: Fatty acid]]
		+	[[Category: Human lipocalin]]
		+	[[Category: Lilial]]
		+	[[Category: Lipid binding protein]]
		+	[[Category: Nasal mucus]]
		+	[[Category: Odorant-binding protein]]
		+	[[Category: Transport protein]]
		+	[[Category: Vanillin]]

OCA at 12:09, 31 December 2014

OCA — Wed, 31 Dec 2014 12:09:19 GMT

←Older revision		Revision as of 12:09, 31 December 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4run is ON HOLD	+	The entry 4run is ON HOLD until Paper Publication

	Authors: Schiefner, A., Skerra, A.		Authors: Schiefner, A., Skerra, A.

OCA at 17:23, 24 December 2014

OCA — Wed, 24 Dec 2014 17:23:16 GMT

←Older revision		Revision as of 17:23, 24 December 2014
Line 6:		Line 6:

	Description: Crystal structure of human odorant binding protein OBPIIa		Description: Crystal structure of human odorant binding protein OBPIIa
		+	[[Category: Unreleased Structures]]
		+	[[Category: Skerra, A]]
		+	[[Category: Schiefner, A]]

OCA: Protected "4run" [edit=sysop:move=sysop]

OCA — Wed, 03 Dec 2014 08:19:10 GMT

Protected "4run" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:19, 3 December 2014

OCA: New page: '''Unreleased structure''' The entry 4run is ON HOLD Authors: Schiefner, A., Skerra, A. Description: Crystal structure of human odorant binding protein OBPIIa

OCA — Wed, 03 Dec 2014 08:19:09 GMT

New page: '''Unreleased structure''' The entry 4run is ON HOLD Authors: Schiefner, A., Skerra, A. Description: Crystal structure of human odorant binding protein OBPIIa

New page

'''Unreleased structure'''

The entry 4run is ON HOLD

Authors: Schiefner, A., Skerra, A.

Description: Crystal structure of human odorant binding protein OBPIIa