4rxy - Revision history

OCA at 12:56, 1 March 2024

OCA — Fri, 01 Mar 2024 12:56:46 GMT

←Older revision		Revision as of 12:56, 1 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4rxy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RXY FirstGlance]. <br>		<table><tr><td colspan='2'>[[4rxy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RXY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.901Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rxy OCA], [https://pdbe.org/4rxy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rxy RCSB], [https://www.ebi.ac.uk/pdbsum/4rxy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rxy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rxy OCA], [https://pdbe.org/4rxy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rxy RCSB], [https://www.ebi.ac.uk/pdbsum/4rxy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rxy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/Q9HVB9_PSEAE Q9HVB9_PSEAE]		[https://www.uniprot.org/uniprot/Q9HVB9_PSEAE Q9HVB9_PSEAE]
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Carbonic anhydrases (CAs) are metallo-enzymes that catalyze the reversible hydration of carbon dioxide into bicarbonate and a proton. The beta-class CAs (beta-CAs) are expressed in prokaryotes, fungi, plants, and more recently have been isolated in some animals. The beta-CA class is divided into two subclasses, termed type I and II, defined by pH catalytic activity profile and active site structural configuration. Type I beta-CAs display catalytic activity over a broad pH range (6.5-9.0) with the active site zinc tetrahedrally coordinated by three amino acids and a hydroxide/water. In contrast, type II beta-CAs are catalytically active only at a pH 8 and higher where they adopt a functional active site configuration like that of type I. However, below pH 8 they are conformationally self-inactivated by the addition of a fourth amino acid coordinating the zinc and thereby displacing the zinc bound solvent. We have determined the structure of psCA3, a type II beta-CA, isolated from Pseudomonas aeruginosa (P. aeruginosa) PAO1 at pH 8.3, in its open active state to a resolution of 1.9A. The active site zinc is coordinated by Cys42, His98, Cys101 and a water/hydroxide molecule. P. aeruginosa is a multi-drug resistant bacterium and displays intrinsic resistance to most of the currently used antibiotics; therefore, there is a need for new antibacterial targets. Kinetic data confirm that psCA3 belongs to the type II subclass and that sulfamide, sulfamic acid, phenylboronic acid and phenylarsonic acid are micromolar inhibitors. In vivo studies identified that among six tested inhibitors representing sulfonamides, inorganic anions, and small molecules, acetazolamide has the most significant dose-dependent inhibitory effect on P. aeruginosa growth.
-
-	Structure and inhibition studies of a type II beta-carbonic anhydrase psCA3 from Pseudomonas aeruginosa.,Pinard MA, Lotlikar SR, Boone CD, Vullo D, Supuran CT, Patrauchan MA, McKenna R Bioorg Med Chem. 2015 Jun 8. pii: S0968-0896(15)00429-0. doi:, 10.1016/j.bmc.2015.05.029. PMID:26068018<ref>PMID:26068018</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4rxy" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Carbonic anhydrase 3D structures\|Carbonic anhydrase 3D structures]]		*[[Carbonic anhydrase 3D structures\|Carbonic anhydrase 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 10:33, 15 March 2023

OCA — Wed, 15 Mar 2023 10:33:13 GMT

←Older revision		Revision as of 10:33, 15 March 2023
Line 1:		Line 1:

	==Crystal Structure of the Beta Carbonic Anhydrase psCA3 isolated from Pseudomonas aeruginosa==		==Crystal Structure of the Beta Carbonic Anhydrase psCA3 isolated from Pseudomonas aeruginosa==
-	<StructureSection load='4rxy' size='340' side='right' caption='[[4rxy]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='4rxy' size='340' side='right'caption='[[4rxy]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4rxy]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Pseae Pseae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RXY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4RXY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4rxy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RXY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PA4676 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rxy OCA], [https://pdbe.org/4rxy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rxy RCSB], [https://www.ebi.ac.uk/pdbsum/4rxy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rxy ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4rxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rxy OCA], [~~http~~://pdbe.org/4rxy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4rxy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4rxy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4rxy ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9HVB9_PSEAE Q9HVB9_PSEAE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4rxy" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4rxy" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Carbonic anhydrase 3D structures\|Carbonic anhydrase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Carbonate dehydratase~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Pseae~~]]	+	[[Category: Pseudomonas aeruginosa PAO1]]
-	[[Category: Mckenna, R]]	+	[[Category: Mckenna R]]
-	[[Category: Pinard~~, M A]]~~	+	[[Category: Pinard MA]]
-	~~[[Category: Lyase]]~~	+
-	~~[[Category: Reversible hydration~~]]	+

OCA at 09:12, 22 November 2017

OCA — Wed, 22 Nov 2017 09:12:04 GMT

←Older revision		Revision as of 09:12, 22 November 2017
Line 3:		Line 3:
	<StructureSection load='4rxy' size='340' side='right' caption='[[4rxy]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='4rxy' size='340' side='right' caption='[[4rxy]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4rxy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RXY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RXY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4rxy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RXY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RXY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PA4676 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rxy OCA], [http://pdbe.org/4rxy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rxy RCSB], [http://www.ebi.ac.uk/pdbsum/4rxy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rxy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rxy OCA], [http://pdbe.org/4rxy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rxy RCSB], [http://www.ebi.ac.uk/pdbsum/4rxy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rxy ProSAT]</span></td></tr>
Line 17:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4rxy" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4rxy" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Carbonic anhydrase\|Carbonic anhydrase]]
	== References ==		== References ==
	<references/>		<references/>
Line 25:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Carbonate dehydratase]]		[[Category: Carbonate dehydratase]]
		+	[[Category: Pseae]]
	[[Category: Mckenna, R]]		[[Category: Mckenna, R]]
	[[Category: Pinard, M A]]		[[Category: Pinard, M A]]
	[[Category: Lyase]]		[[Category: Lyase]]
	[[Category: Reversible hydration]]		[[Category: Reversible hydration]]

OCA at 16:09, 17 May 2017

OCA — Wed, 17 May 2017 16:09:01 GMT

←Older revision		Revision as of 16:09, 17 May 2017
Line 1:		Line 1:
		+
	==Crystal Structure of the Beta Carbonic Anhydrase psCA3 isolated from Pseudomonas aeruginosa==		==Crystal Structure of the Beta Carbonic Anhydrase psCA3 isolated from Pseudomonas aeruginosa==
	<StructureSection load='4rxy' size='340' side='right' caption='[[4rxy]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='4rxy' size='340' side='right' caption='[[4rxy]], [[Resolution\|resolution]] 1.90Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rxy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rxy RCSB], [http://www.ebi.ac.uk/pdbsum/4rxy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rxy OCA], [http://pdbe.org/4rxy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rxy RCSB], [http://www.ebi.ac.uk/pdbsum/4rxy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rxy ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4rxy" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Carbonic anhydrase\|Carbonic anhydrase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:54, 24 June 2015

OCA — Wed, 24 Jun 2015 12:54:27 GMT

←Older revision		Revision as of 12:54, 24 June 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal Structure of the Beta Carbonic Anhydrase psCA3 isolated from Pseudomonas aeruginosa==
		+	<StructureSection load='4rxy' size='340' side='right' caption='[[4rxy]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4rxy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RXY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RXY FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rxy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rxy RCSB], [http://www.ebi.ac.uk/pdbsum/4rxy PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Carbonic anhydrases (CAs) are metallo-enzymes that catalyze the reversible hydration of carbon dioxide into bicarbonate and a proton. The beta-class CAs (beta-CAs) are expressed in prokaryotes, fungi, plants, and more recently have been isolated in some animals. The beta-CA class is divided into two subclasses, termed type I and II, defined by pH catalytic activity profile and active site structural configuration. Type I beta-CAs display catalytic activity over a broad pH range (6.5-9.0) with the active site zinc tetrahedrally coordinated by three amino acids and a hydroxide/water. In contrast, type II beta-CAs are catalytically active only at a pH 8 and higher where they adopt a functional active site configuration like that of type I. However, below pH 8 they are conformationally self-inactivated by the addition of a fourth amino acid coordinating the zinc and thereby displacing the zinc bound solvent. We have determined the structure of psCA3, a type II beta-CA, isolated from Pseudomonas aeruginosa (P. aeruginosa) PAO1 at pH 8.3, in its open active state to a resolution of 1.9A. The active site zinc is coordinated by Cys42, His98, Cys101 and a water/hydroxide molecule. P. aeruginosa is a multi-drug resistant bacterium and displays intrinsic resistance to most of the currently used antibiotics; therefore, there is a need for new antibacterial targets. Kinetic data confirm that psCA3 belongs to the type II subclass and that sulfamide, sulfamic acid, phenylboronic acid and phenylarsonic acid are micromolar inhibitors. In vivo studies identified that among six tested inhibitors representing sulfonamides, inorganic anions, and small molecules, acetazolamide has the most significant dose-dependent inhibitory effect on P. aeruginosa growth.

-	~~The entry 4rxy is ON HOLD until Paper Publication~~	+	Structure and inhibition studies of a type II beta-carbonic anhydrase psCA3 from Pseudomonas aeruginosa.,Pinard MA, Lotlikar SR, Boone CD, Vullo D, Supuran CT, Patrauchan MA, McKenna R Bioorg Med Chem. 2015 Jun 8. pii: S0968-0896(15)00429-0. doi:, 10.1016/j.bmc.2015.05.029. PMID:26068018<ref>PMID:26068018</ref>

-	~~Authors: Pinard~~, M.A.~~, Mckenna, R~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description: Crystal Structure of the Beta Carbonic Anhydrase psCA3 isolated from Pseudomonas aeruginosa~~	+	== References ==
-	~~[[Category: Unreleased Structures]]~~	+	<references/>
-	[[Category: ~~Pinard, M.A~~]]	+	__TOC__
		+	</StructureSection>
		+	[[Category: Carbonate dehydratase]]
	[[Category: Mckenna, R]]		[[Category: Mckenna, R]]
		+	[[Category: Pinard, M A]]
		+	[[Category: Lyase]]
		+	[[Category: Reversible hydration]]

OCA at 14:05, 21 January 2015

OCA — Wed, 21 Jan 2015 14:05:11 GMT

←Older revision		Revision as of 14:05, 21 January 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4rxy is ON HOLD	+	The entry 4rxy is ON HOLD until Paper Publication

	Authors: Pinard, M.A., Mckenna, R.		Authors: Pinard, M.A., Mckenna, R.

OCA at 17:35, 24 December 2014

OCA — Wed, 24 Dec 2014 17:35:50 GMT

←Older revision		Revision as of 17:35, 24 December 2014
Line 6:		Line 6:

	Description: Crystal Structure of the Beta Carbonic Anhydrase psCA3 isolated from Pseudomonas aeruginosa		Description: Crystal Structure of the Beta Carbonic Anhydrase psCA3 isolated from Pseudomonas aeruginosa
		+	[[Category: Unreleased Structures]]
		+	[[Category: Pinard, M.A]]
		+	[[Category: Mckenna, R]]

OCA: Protected "4rxy" [edit=sysop:move=sysop]

OCA — Wed, 24 Dec 2014 09:32:06 GMT

Protected "4rxy" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:32, 24 December 2014

OCA: New page: '''Unreleased structure''' The entry 4rxy is ON HOLD Authors: Pinard, M.A., Mckenna, R. Description: Crystal Structure of the Beta Carbonic Anhydrase psCA3 isolated from Pseudomonas ae...

OCA — Wed, 24 Dec 2014 09:32:05 GMT

New page: '''Unreleased structure''' The entry 4rxy is ON HOLD Authors: Pinard, M.A., Mckenna, R. Description: Crystal Structure of the Beta Carbonic Anhydrase psCA3 isolated from Pseudomonas ae...

New page

'''Unreleased structure'''

The entry 4rxy is ON HOLD

Authors: Pinard, M.A., Mckenna, R.

Description: Crystal Structure of the Beta Carbonic Anhydrase psCA3 isolated from Pseudomonas aeruginosa